LOCUS       NM_057200               6031 bp    mRNA    linear   ROD 28-JUL-2024
DEFINITION  Rattus norvegicus kinesin family member 1B (Kif1b), mRNA.
ACCESSION   NM_057200
VERSION     NM_057200.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6031)
  AUTHORS   Gumy,L.F., Katrukha,E.A., Grigoriev,I., Jaarsma,D., Kapitein,L.C.,
            Akhmanova,A. and Hoogenraad,C.C.
  TITLE     MAP2 Defines a Pre-axonal Filtering Zone to Regulate KIF1- versus
            KIF5-Dependent Cargo Transport in Sensory Neurons
  JOURNAL   Neuron 94 (2), 347-362 (2017)
   PUBMED   28426968
REFERENCE   2  (bases 1 to 6031)
  AUTHORS   Chen,J.H., Wang,Y.Y., Lv,W.B., Gan,Y., Chang,W., Tian,N.N.,
            Huang,X.H., Liu,L., Yu,X.F. and Chen,S.D.
  TITLE     Effects of interactions between environmental factors and KIF1B
            genetic variants on the risk of hepatocellular carcinoma in a
            Chinese cohort
  JOURNAL   World J Gastroenterol 22 (16), 4183-4190 (2016)
   PUBMED   27122668
REFERENCE   3  (bases 1 to 6031)
  AUTHORS   Shi,T.Y., Jiang,Z., Jiang,R., Yin,S., Wang,M.Y., Yu,K.D.,
            Shao,Z.M., Sun,M.H., Zang,R. and Wei,Q.
  TITLE     Polymorphisms in the kinesin-like factor 1 B gene and risk of
            epithelial ovarian cancer in Eastern Chinese women
  JOURNAL   Tumour Biol 36 (9), 6919-6927 (2015)
   PUBMED   25854172
REFERENCE   4  (bases 1 to 6031)
  AUTHORS   Yang,S.Z., Wang,J.T., Yu,W.W., Liu,Q., Wu,Y.F. and Chen,S.G.
  TITLE     Downregulation of KIF1B mRNA in hepatocellular carcinoma tissues
            correlates with poor prognosis
  JOURNAL   World J Gastroenterol 21 (27), 8418-8424 (2015)
   PUBMED   26217094
REFERENCE   5  (bases 1 to 6031)
  AUTHORS   Lin,M.Y. and Sheng,Z.H.
  TITLE     Regulation of mitochondrial transport in neurons
  JOURNAL   Exp Cell Res 334 (1), 35-44 (2015)
   PUBMED   25612908
  REMARK    Review article
REFERENCE   6  (bases 1 to 6031)
  AUTHORS   Mok,H., Shin,H., Kim,S., Lee,J.R., Yoon,J. and Kim,E.
  TITLE     Association of the kinesin superfamily motor protein KIF1Balpha
            with postsynaptic density-95 (PSD-95), synapse-associated
            protein-97, and synaptic scaffolding molecule PSD-95/discs
            large/zona occludens-1 proteins
  JOURNAL   J Neurosci 22 (13), 5253-5258 (2002)
   PUBMED   12097473
REFERENCE   7  (bases 1 to 6031)
  AUTHORS   Zhao,C., Takita,J., Tanaka,Y., Setou,M., Nakagawa,T., Takeda,S.,
            Yang,H.W., Terada,S., Nakata,T., Takei,Y., Saito,M., Tsuji,S.,
            Hayashi,Y. and Hirokawa,N.
  TITLE     Charcot-Marie-Tooth disease type 2A caused by mutation in a
            microtubule motor KIF1Bbeta
  JOURNAL   Cell 105 (5), 587-597 (2001)
   PUBMED   11389829
  REMARK    Erratum:[Cell 2001 Jul 13;106(1):127]
REFERENCE   8  (bases 1 to 6031)
  AUTHORS   Faire,K., Gruber,D. and Bulinski,J.C.
  TITLE     Identification of kinesin-like molecules in myogenic cells
  JOURNAL   Eur J Cell Biol 77 (1), 27-34 (1998)
   PUBMED   9808286
REFERENCE   9  (bases 1 to 6031)
  AUTHORS   Kim,E., Niethammer,M., Rothschild,A., Jan,Y.N. and Sheng,M.
  TITLE     Clustering of Shaker-type K+ channels by interaction with a family
            of membrane-associated guanylate kinases
  JOURNAL   Nature 378 (6552), 85-88 (1995)
   PUBMED   7477295
REFERENCE   10 (bases 1 to 6031)
  AUTHORS   Nangaku,M., Sato-Yoshitake,R., Okada,Y., Noda,Y., Takemura,R.,
            Yamazaki,H. and Hirokawa,N.
  TITLE     KIF1B, a novel microtubule plus end-directed monomeric motor
            protein for transport of mitochondria
  JOURNAL   Cell 79 (7), 1209-1220 (1994)
   PUBMED   7528108
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB070355.1.
            
            On Feb 21, 2013 this sequence version replaced NM_057200.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB070355.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-6031              AB070355.1         1-6031
FEATURES             Location/Qualifiers
     source          1..6031
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..6031
                     /gene="Kif1b"
                     /note="kinesin family member 1B"
                     /db_xref="GeneID:117548"
                     /db_xref="RGD:621520"
     exon            1..285
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            286..460
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     CDS             355..5805
                     /gene="Kif1b"
                     /EC_number="5.6.1.3"
                     /note="kinesin-family protein KIF1Bbeta3"
                     /codon_start=1
                     /product="kinesin-like protein KIF1B"
                     /protein_id="NP_476548.1"
                     /db_xref="GeneID:117548"
                     /db_xref="RGD:621520"
                     /translation="MSGASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPK
                     EAPKSFSFDYSYWSHTSPEDPCFASQSRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAG
                     KSYTMMGKQEESQAGIIPQLCEELFEKINDNCNEDMSYSVEVSYMEIYCERVRDLLNP
                     KNKGNLRVREHPLLGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSH
                     AVFTIVFTQKKQDPETNLSTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLT
                     TLGKVISALAEVDNCTSKSKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPA
                     DINYDETLSTLRYADRAKQIKCNAVINEDPNAKLVRELKEEVTRLKDLLRAQGLGDII
                     DIDPLMDDYSGSGGKYLKDFQNNKHRYLLASENQRPGNFSTASMGSLTSSPSSCSLNS
                     QAGLTSVTSIQERIMSTPGGEEAIERLKESEKIIAELNETWEEKLRKTEAIRMEREAL
                     LAEMGVAIREDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGITRVGQADAERR
                     QDIVLSGAHIKEEHCIFRSERNNTGEVIVTLEPCERSETYVNGKRVAHPVQLRSGNRI
                     IMGKNHVFRFNHPEQARAEREKTPSAETPSEPVDWTFAQRELLEKQGIDMKQEMEKRL
                     QEMEILYKREKEEADLLLEQQRLDYESKLQALQKQVETRSLAAETTEEEEEEEEVPWT
                     QHEFELAQWAFRKWKSHQFTSLRDLLWGNAVYLKEANAISVELKKKVQFQFVLLTDTL
                     YSPVPPELLPTEMGKTHEDRPFPRTVVAVEVQDLKNGATHYWSLDKLKQRLDLMREMY
                     DRAGEVGSNAQDDSETTMTGSDPFYDRFHWFKLVGSSPIFHGCVNERLADRTPSPTFS
                     TADSDITELADEQQDAMEDFDDEAFVDDTGSDAGTEEGSELFSDGHDPFYDRSPWFIL
                     VGRAFVYLSNLLYPVPLIHRVAIVSEKGEVRGFLRVAVQAIAADEEAPDYGSGIRQSG
                     TAKISFDNEYFNQSDFPSAAMTRSGLSLEELRIVEGQGQSSEVISPPEEVNRMNDLDL
                     KSGTLLDGKMVMEGFSEEIGNHLKLGSAFTFRVTVLQASGILPEYADIFCQFNFLHRH
                     DEAFSTEPLKNNGRGSPLGFYHVQNIAVEVTESFVDYIKTKPIVFEVFGHYQQHPLHL
                     QGQELNSPPQPSRRFFPPPMPLSRPVPATKLNTMNKTSLGQSMSKYDLLVWFEISELE
                     PTGEYIPAVVDHTAGLPCQGTFLLHQGIQRRITVTIIHEKGSELHWKDVRELVVGRIR
                     NKPEVDEAAVDAILSLNIISAKSLKSSHSSSRTFYRFEAVWDSSLHNSLLLNRVTPYG
                     EKIYMTLSAYLELDHCIQPAVITKDVCMVFYSRDAKISPPRSLRNLFGSGYSKSPDSN
                     RVTGIYELSLCKMADTGSPGMQRRRRKVLDTSVAYVRGEENLAGWRPRGDSLILEHQW
                     ELEKLELLHEVEKTRHFLLLRERLGDSIPKSMSDSLSPSLSSGTLSTSTSISSQISTT
                     TFESAITPSESSGYDSADIESLVDREKELATKCLQLLTHTFNREFSQVHGSISDCKLS
                     DISPIGRDPSVSSFSSSTLTPSSTCPSLVDSRSSSMDQKTPEANSRASSPCQEFEQFQ
                     IIPTVETPYLARAGKNEFLNLVPDIEEVRAGSVVSKKGYLHFKEPLSSNWAKHFVVVR
                     RPYVFIYNSDKDPVERGIINLSTAQVEYSEDQQAMLKTPNTFAVCTKHRGVLLQALND
                     KDMNDWLYAFNPLLAGTIRSKLSRRCPSQPKY"
     exon            461..537
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            538..717
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            718..783
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            784..962
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            963..1074
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1075..1152
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1153..1218
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1219..1236
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1237..1312
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1313..1391
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1392..1534
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1535..1576
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1577..1788
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1789..1868
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1869..1944
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            1945..2024
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            2025..2131
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            2132..2215
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            2216..2396
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            2397..2469
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            2470..2563
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            2564..2712
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            2713..2891
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            2892..3029
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            3030..3278
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            3279..3397
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            3398..3483
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            3484..3613
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            3614..3776
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            3777..3867
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            3868..3986
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            3987..4042
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            4043..4151
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            4152..4218
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            4219..4303
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            4304..4409
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            4410..4524
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            4525..4658
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            4659..4720
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            4721..4866
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            4867..5106
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            5107..5178
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            5179..5300
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            5301..5450
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            5451..5643
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            5644..5762
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
     exon            5763..6031
                     /gene="Kif1b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagcagcgac gcggtgtagt cagacggcag tggtcctggg aggcgacagc tcgggtccgg
       61 gcttctctct gcttctccgc cgcatccacc gccgcgcccc ggcctcccgc caatcctcga
      121 tgcagagctg ggcggccgcg tgatggggct gcggagcggc gccctgcggc tcgcggcggc
      181 cgctgcctgc gctgaggtgc gtcggtgccc ggcctcccgc gcccctgcgc gccgcggcgt
      241 cttctgactc ggccggctcg cccgtcggtc cgcagcgcgg ctgaggaacc ttgaacataa
      301 cttcaaaaga agatttgatt tttacttctg gactgcatat agaaggccat cagaatgtcg
      361 ggagcctctg tgaaggtagc cgttcgagtg aggcccttca attcccgaga gaccagcaag
      421 gagtccaagt gcatcattca gatgcagggc aactcgacca gtattatcaa cccaaagaac
      481 ccaaaggaag caccaaagtc cttcagcttt gactactctt actggtctca cacctcgcct
      541 gaagacccct gctttgcatc tcagagccgc gtgtacaatg acattgggaa ggagatgctc
      601 ttgcatgcct tcgaaggcta taatgtctgt atctttgcct atgggcagac cggtgctggg
      661 aaatcctaca cgatgatggg gaaacaagaa gagagccagg ccgggatcat cccacagttg
      721 tgtgaagaac tttttgagaa gatcaatgac aactgtaatg aagatatgtc ttactccgtg
      781 gaggtgagct acatggaaat ttactgtgag agagtacgag atttgctgaa tcccaaaaac
      841 aagggtaatt tgcgtgtgcg tgaacaccca cttctcggac cctatgtgga agatctgtcc
      901 aagctggcag tcacttccta cactgacatt gctgacctca tggatgctgg gaacaaagcc
      961 aggacggtgg cagctaccaa catgaacgag acgagtagcc gttcccacgc tgtgtttacc
     1021 attgttttta cccagaagaa acaggatcct gagacgaacc tttctactga gaaggtcagt
     1081 aaaatcagcc tggtggatct agcaggaagt gaacgagctg attcaactgg cgccaaagga
     1141 actcgattaa aggaaggtgc aaatattaac aagtctctta caactttggg caaagtcatt
     1201 tcggccttgg cagaggtgga taactgcaca agcaagagta aaaagaagaa gaaaactgat
     1261 tttattcctt acagggattc tgttcttact tggctccttc gagaaaatct aggtggcaac
     1321 tcccgaactg caatggtggc tgctctgagt cccgcagaca tcaactatga tgaaaccttg
     1381 agcacgctga gatatgcaga tcgtgcaaaa cagattaaat gcaacgctgt tatcaatgag
     1441 gacccgaatg ccaagctggt tcgggagctg aaggaggaag tgacccgact gaaggacctt
     1501 ctccgtgctc aggggctggg ggacattatc gatattgatc cattgatgga tgattactct
     1561 ggaagtggag gcaaatatct gaaagatttt cagaacaata agcataggta cttgctagcc
     1621 tctgagaatc aacgccctgg caatttctcc acagcatcca tggggtccct cacttcatcc
     1681 ccgtcttcat gctcacttaa tagtcaggcg ggcctaacct ctgtgaccag tattcaagag
     1741 aggattatgt ctacacctgg aggggaggaa gccattgaac gtctgaagga gtcagagaag
     1801 atcattgctg agttgaatga aacctgggaa gagaaacttc gtaaaacaga ggccatcaga
     1861 atggagagag aagccttgtt ggctgagatg ggagttgcca tacgggaaga tgggggaaca
     1921 cttggcgttt tctcacctaa aaagactcca caccttgtta acctcaatga agaccctcta
     1981 atgtcggagt gtttgcttta ttatatcaag gacggaatta caagggttgg ccaagcagat
     2041 gctgagcggc gccaggacat cgtgctgagt ggggcccaca ttaaagaaga gcattgtatc
     2101 tttcggagtg agagaaacaa cactggcgaa gttattgtga ccttagagcc ctgtgagcgc
     2161 tcagaaacct atgtgaatgg caagagggtg gcccatcctg ttcagctgcg ctcagggaac
     2221 cgtatcatca tgggtaaaaa tcatgttttc cgctttaacc accctgagca agctcgagca
     2281 gagcgggaga agactccctc tgctgagacc ccctctgagc ctgtggattg gacatttgct
     2341 cagagagaac ttcttgaaaa acaagggatt gatatgaaac aggagatgga gaaaaggctt
     2401 caggaaatgg agatccttta caaaagggag aaggaggaag ctgaccttct tctggagcag
     2461 cagaggctgg actatgagag taaattgcag gccttgcaga agcaggttga gactcgatct
     2521 ctggctgcag agaccacgga agaggaagag gaggaggagg aagttccttg gacacagcat
     2581 gaatttgagt tggcccagtg ggcgttccgg aaatggaagt ctcaccagtt tacttcgtta
     2641 agggacttac tctggggcaa tgcggtgtac ctgaaggaag ccaatgccat cagtgtggaa
     2701 ctgaagaaaa aggtgcagtt ccagttcgtt ctgctgactg acacactata ctcccctgtg
     2761 cctcccgaac tgcttcccac ggagatgggg aaaacccacg aggacaggcc tttccctcgg
     2821 acagtggtgg ctgtggaagt ccaggacctg aagaatggag caacacatta ttggtctttg
     2881 gataagctca agcagagact ggatctaatg cgagagatgt atgacagggc aggtgaggtg
     2941 ggctccaatg cccaagacga cagcgagacg accatgacag gcagcgaccc gttttacgat
     3001 cggttccact ggttcaaact tgtgggaagc tcccctattt tccacggctg tgtgaatgag
     3061 cgccttgccg accgcacacc ctcccccact ttttccacgg ccgattccga catcactgaa
     3121 ctggctgacg agcagcagga tgccatggag gactttgatg atgaggcctt cgtggatgac
     3181 accggctctg acgcagggac ggaggaggga tcagagctct tcagtgatgg gcatgaccca
     3241 ttttacgacc gatccccttg gttcatttta gtaggaaggg catttgtgta cttgagcaac
     3301 ctgctgtatc cagtgcccct gattcacagg gtggccatcg tcagtgagaa gggggaagtg
     3361 cggggcttcc ttcgagtggc tgtgcaggcc attgcagcgg atgaagaagc tcctgattat
     3421 ggctctggaa ttcgacagtc aggaacagct aaaatatctt ttgataatga gtactttaat
     3481 cagagtgact tcccttcagc tgcaatgact cgttctggtc tgtccttgga ggagctgagg
     3541 attgttgagg gacagggcca gagttctgaa gtcatcagtc ctccagaaga agtcaatcga
     3601 atgaatgact tggatttgaa gtcgggcact ctgctggacg ggaagatggt gatggaagga
     3661 ttttccgaag agattggtaa ccacctgaaa ctgggcagtg cgttcacttt ccgagtcact
     3721 gtgctccagg ccagtggcat cctgccggag tatgcagaca tcttttgtca gttcaacttt
     3781 ttgcatcggc atgacgaagc gttctccact gaacccctga agaacaacgg aagaggaagt
     3841 cccctgggct tttaccatgt acagaatatt gcagtggagg tcaccgagtc atttgtggac
     3901 tacatcaaaa ccaaacccat cgtgtttgag gtcttcgggc attaccagca gcacccactt
     3961 catctgcaag gacaagagct taacagtcca cctcagccat ctcgaagatt cttcccccca
     4021 cccatgccac tctccagacc agttccagcc actaagttaa acaccatgaa caaaaccagc
     4081 cttgggcaaa gcatgagcaa gtacgacctt ctggtttggt ttgagatcag tgaactggag
     4141 cctactggag agtatattcc agctgtggtt gaccatacag caggcttgcc ctgccagggg
     4201 acatttttgc tgcaccaggg catccagcga cggatcacag tgactattat ccatgagaag
     4261 ggcagtgagc tccactggaa agatgtccgt gagctggtgg taggtcggat taggaataaa
     4321 cctgaggtgg atgaagctgc agttgatgct atcctttccc taaacatcat ctctgctaag
     4381 tccctcaagt cttctcacag ctccagcagg accttctacc gctttgaggc tgtatgggac
     4441 agctccctac ataactccct ccttctgaac cgagtgacac cctatggaga aaagatctac
     4501 atgaccttat ctgcttatct ggagttggat cattgcatcc agccagccgt catcactaag
     4561 gatgtgtgca tggtcttcta ttcccgagat gccaagatct caccaccacg ttctctgaga
     4621 aacctctttg gtagtggcta ctcaaagtca ccagactcca accgagtaac tggaatctac
     4681 gagcttagct tatgcaaaat ggcagatact gggagcccag gcatgcagag gcggaggaga
     4741 aaagtcttgg atacctcggt ggcgtatgtt cggggagagg agaacctcgc aggctggcga
     4801 cctcgtggag acagcctcat cctggaacac caatgggagc tggagaagct ggagcttctg
     4861 catgaggtgg aaaaaactcg ccacttcttg ctgcttcggg agagacttgg tgacagcata
     4921 cccaagtcta tgagtgactc actgtccccc agcctcagca gtggaaccct tagcacctcg
     4981 accagcatct cttctcagat ctcaaccact acctttgaaa gcgccatcac accgagcgag
     5041 agcagtggct acgactcagc agacattgaa agcctggtag accgagagaa agaactggct
     5101 acaaagtgcc tgcagcttct cacccacact ttcaaccgag aattcagcca ggtacatggc
     5161 agcatcagtg actgtaagtt gtctgacatc tctccgattg gacgcgaccc ctcggtgtcc
     5221 agtttcagca gttccaccct cacgccctcc tccacatgcc cctccctggt ggactccagg
     5281 agcagctcta tggatcagaa gaccccagaa gccaactctc gtgcgtctag tccttgccag
     5341 gaatttgaac agtttcagat catcccaact gtggagacac cctatttggc ccgagcagga
     5401 aagaatgaat ttctcaatct tgttccagac attgaagaag ttagagcagg ctcagtggtg
     5461 tctaagaaag gatacctgca tttcaaagag ccactctcca gtaactgggc taaacatttc
     5521 gttgtggttc gtcgccctta cgtcttcatc tataacagtg acaaagaccc agtagagcgt
     5581 ggcatcatta acctgtccac agcacaggtg gagtacagcg aggaccagca ggccatgctg
     5641 aagacaccta acacttttgc tgtgtgcaca aagcaccgtg gggtccttct gcaagctctc
     5701 aatgacaaag acatgaatga ctggttatac gcctttaacc cactcctggc tggcacaata
     5761 aggtcaaaac tctctcgcag atgcccaagc cagccaaaat actaagcgac cctcctgagc
     5821 cttgctcacc ttcgacagat aaagaaagtg ttacctctca ttctctttgt gactcttgac
     5881 ggttattctt gtatgtaatc ctgtggctta acgactttcc ctcgtcatcc tgcacttctc
     5941 tagttctcct gctccctatc tccatggctc tgtcctctct tcattcttgt gctgacttgt
     6001 agcatgtggc ctaacaaagg ggaacaaatc c
//
