LOCUS       NM_181635               4214 bp    mRNA    linear   ROD 29-JUN-2024
DEFINITION  Rattus norvegicus kinesin family member 15 (Kif15), mRNA.
ACCESSION   NM_181635
VERSION     NM_181635.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4214)
  AUTHORS   Wu,S., Lv,L., Li,L., Wang,L., Mao,B., Li,J., Shen,X., Ge,R.,
            Wong,C.K.C., Sun,F. and Cheng,C.Y.
  TITLE     KIF15 supports spermatogenesis via its effects on Sertoli cell
            microtubule, actin, vimentin, and septin cytoskeletons
  JOURNAL   Endocrinology 162 (4) (2021)
   PUBMED   33453102
  REMARK    GeneRIF: KIF15 supports spermatogenesis via its effects on Sertoli
            cell microtubule, actin, vimentin, and septin cytoskeletons.
REFERENCE   2  (bases 1 to 4214)
  AUTHORS   Feng,J., Hu,Z., Chen,H., Hua,J., Wu,R., Dong,Z., Qiang,L., Liu,Y.,
            Baas,P.W. and Liu,M.
  TITLE     Depletion of kinesin-12, a myosin-IIB-interacting protein, promotes
            migration of cortical astrocytes
  JOURNAL   J Cell Sci 129 (12), 2438-2447 (2016)
   PUBMED   27170353
  REMARK    GeneRIF: kinesin-12 depletion from cultured rat cortical astrocytes
            decreases cell proliferation but increases migration.
REFERENCE   3  (bases 1 to 4214)
  AUTHORS   Liu,M., Nadar,V.C., Kozielski,F., Kozlowska,M., Yu,W. and Baas,P.W.
  TITLE     Kinesin-12, a mitotic microtubule-associated motor protein, impacts
            axonal growth, navigation, and branching
  JOURNAL   J Neurosci 30 (44), 14896-14906 (2010)
   PUBMED   21048148
  REMARK    GeneRIF: Kinesin-12 shares functions with kinesin-5 related to
            microtubule-microtubule interactions, but kinesin-12 has other
            functions not shared by kinesin-5 that are related to the ability
            of kinesin-12 to interact with actin.
REFERENCE   4  (bases 1 to 4214)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY291580.1.
            
            On Jun 17, 2003 this sequence version replaced NM_181635.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY291580.1, AY291581.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132291, SAMD00132292
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4214
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..4214
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /note="kinesin family member 15"
                     /db_xref="GeneID:353302"
                     /db_xref="RGD:727790"
     exon            1..45
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     CDS             27..4184
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /note="kinesin-like protein 2; kinesin-like 7"
                     /codon_start=1
                     /product="kinesin-like protein KIF15"
                     /protein_id="NP_853666.1"
                     /db_xref="GeneID:353302"
                     /db_xref="RGD:727790"
                     /translation="MAPGCKSELRNVTNSHSNQPSNEDDAIKVFVRIRPAEEGARSAD
                     GEQSLCLSVLSQTALRLHSNPDPKTFVFDYVAGMDTTQESVFSTVAKSIVESCMSGYN
                     GTIFAYGQTGSGKTFTMMGPSDSDNFSHNLRGVIPRSFEYLFSLIDREKEKAGAGKSF
                     LCKCSFIEVYNEQIYDLLDSASVGLYLREHIKKGVFVVGAVEQVVASAAEAYQVLSRG
                     WRNRRVASTSMNRESSRSHAVFTITIESMEKSSEAVNIRTSLLNLVDLAGSERQKDTH
                     AEGMRLKEAGNINRSLSCLGQVITALVDVGNGKQRHVCYRDSKLTFLLRDSLGGNAKT
                     AIIANVHPGSRCFGETLSTLNFAQRAKLIKNKAVVNEDTQGNVSQLQAEVKRLREQLS
                     QFTSGQLTPGSSLARDKEKANYMEYFLEAMLFFKKSEQEKKSLVEKITQLEDLTLKKE
                     KFIQSNKMIVKFREDQIMRLERRQKEARGSFLPEEQDRLLSELRDEIRTLREQVEHHP
                     RLAKYAMENHSLREENRKLKLLAPVKRAHELDAQAIARLEQAFSEVSSTETNDIGLQG
                     LPPKAIKEPSFFTSTEKLKVQLLQIQTELNNSKQEYEEFKELTRKKQLELESELQSLQ
                     KANLNLENLLEATKVCKRQEVSQLNKIHAETLKIITTPTKAYQLCSRLVPKSSPEVGS
                     FGFLRSQSAPDNDILNEPVPPEMSEQALEAISEELRTVQEQLSVLQVKLDEEEHKNLK
                     LQQNVDRLEHHSTQMQELFSSERSDWSKQQQDYLTQLSDLEKQLQDAQTKNDFLKCEV
                     HDLRIVLNSADKELSLVKLEYSTFKESQEKELSQLSDRHVQVQLQLDNARLENEKLLE
                     SQACLQDSYDNLQEVMKFEVDQLSKNLQNCKQENETLKSDLHNLVELFEAEKERNNKL
                     SLQFEEDKENSSKEILKALETVRQEKQEEMARCEKQMAKVQELEESLLAAENVVSCLE
                     KSRESDKELVTNLMNQIQELRTSAGEKSEAIDTLKQELQDISCKYTAAVADKEESKEL
                     IRRQEVDILELKETLRLRILSEDIERDMLCEDLAHATEQLNMLTEASKKHSGLLQSAQ
                     EELTKKEALIQELQHKLNQEKEEVEQKKSEYNLKMKQLEHVMGSAPEYPQSPKTPPHF
                     QTHLAKLLETQEQEIEDGRASKMSLQHLVTKLNEDREVKNAEILRMKDQLCEMENLRL
                     ESQQLRERTWLLQTQLDDMKRQGESSSQSRPDSQQLKNEYEEEIIRERLAKNKLIEEM
                     LKMKTDLEEVQSALDSKEKFCHRMSEEVERTRTLESRAFQEKEQLRSKLEEMYEERER
                     TCQEMEMLRKQLEFLAEENGKLIGHQNLHQKIQYVVRLKKENIRLAEETEKLRAENVF
                     LKERKKE"
     exon            46..88
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            89..272
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            273..349
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            350..387
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            388..485
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            486..665
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            666..875
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            876..1001
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            1002..1124
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            1125..1248
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            1249..1325
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            1326..1535
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            1536..1713
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            1714..1855
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            1856..1997
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            1998..2189
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            2190..2297
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            2298..2403
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            2404..2569
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            2570..2720
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            2721..2806
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            2807..2876
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            2877..2963
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            2964..3068
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            3069..3191
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            3192..3338
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            3339..3440
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            3441..3605
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            3606..3715
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            3716..3791
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            3792..3829
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            3830..3995
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            3996..4127
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
     exon            4128..4214
                     /gene="Kif15"
                     /gene_synonym="Knsl7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtaagcaaat ctcggacggg gtctccatgg ctcctggctg caaatctgag ttacggaatg
       61 tgacaaattc tcattctaac cagccaagta acgaagatga tgccatcaaa gtttttgtgc
      121 ggattcgccc tgctgaagag ggcgctaggt cagctgatgg agagcagagc ctctgcttgt
      181 ctgtgctctc ccagactgct ctccggctgc actccaaccc agaccccaag acctttgtat
      241 tcgattatgt tgcaggcatg gacaccactc aggagtctgt attttcaaca gtggctaaaa
      301 gcattgtgga gtcttgcatg agtggttaca acgggaccat ctttgcatat gggcagactg
      361 gctctgggaa gacatttact atgatgggac catcggactc tgataatttt tctcataatc
      421 taagaggagt aattccacga agttttgaat atttgttttc cttaattgat cgtgaaaaag
      481 aaaaggctgg agctgggaag agtttccttt gtaagtgctc cttcattgag gtctacaatg
      541 agcagatata cgacctgctg gactctgcat cggtcggact gtatttaaga gagcacataa
      601 agaagggcgt cttcgtggtt ggtgcagtgg agcaggtggt ggcctcagct gctgaagcct
      661 accaggtctt atctagaggc tggaggaaca ggcgtgtagc atcaacatct atgaacagag
      721 aatcttccag gtctcatgca gtctttacaa tcacaataga atcaatggag aaaagcagtg
      781 aggctgtgaa cattcggacc tccttactca acctggtgga cttagcagga tctgagaggc
      841 aaaaagacac ccatgcagaa gggatgaggt tgaaggaggc aggtaacata aaccgatcac
      901 tgagctgcct gggccaagtc atcactgccc ttgttgatgt gggcaatggg aaacagaggc
      961 atgtctgcta ccgggactcc aaacttacct tcttacttcg ggactccctt ggtggcaatg
     1021 ccaaaacagc cataattgca aatgttcatc caggatccag gtgttttggg gaaacactgt
     1081 caacacttaa ttttgctcaa agagccaagc tgattaaaaa caaggctgtg gtaaatgaag
     1141 acacccaagg aaatgtgagc cagctacaag ctgaagtgaa gagactcaga gaacaactgt
     1201 ctcagtttac gtctgggcag ctgacaccag gaagctcatt ggccagagat aaagagaagg
     1261 ctaattacat ggaatatttc ctggaagcaa tgttattctt taagaaatct gaacaggaaa
     1321 agaagtctct agtagaaaaa attacccaac tagaagacct caccctcaaa aaggaaaaat
     1381 ttattcagtc taataaaatg attgtgaagt tccgagagga ccaaatcatg cgtctggaaa
     1441 ggcgccagaa ggaggcgcga ggaagcttcc tgccggagga gcaggatcgc ctgctgtcag
     1501 aactgaggga tgagatccgg acgcttcgag agcaagtgga gcaccatccc agactcgcga
     1561 agtatgctat ggagaatcat tccctcaggg aagagaatag aaaactgaaa ttattagcac
     1621 ctgtgaaaag agcccatgaa ctcgatgccc aggctattgc tcgactagaa caggcttttt
     1681 ctgaagtgtc tagtacagag acaaatgaca taggtctgca aggacttcct cccaaagcaa
     1741 taaaagaacc aagtttcttc acaagcaccg agaagttaaa agtacaactc ctgcaaattc
     1801 agacagagct gaataattca aagcaagagt atgaagagtt caaagagtta actcggaaga
     1861 agcagctaga attagaatca gagcttcagt ccttgcaaaa agcaaacctc aatcttgaaa
     1921 accttttgga ggcaacaaaa gtctgcaaac gccaggaagt ttctcagctg aataaaatac
     1981 atgctgaaac actcaagata attaccactc caaccaaggc ttatcagctt tgttctagac
     2041 tagtaccaaa gtcaagccct gaggtgggga gctttggctt cctgcgctca cagagtgctc
     2101 cagataatga tatattgaat gagccagtgc cacctgagat gagtgaacaa gctctggagg
     2161 ccatttctga ggagcttcga actgtgcagg aacaactgag tgttcttcaa gtcaagctgg
     2221 atgaagaaga acataaaaac ctgaaacttc aacagaatgt tgacagacta gaacaccatt
     2281 ctacacaaat gcaggagctg ttctcatcag aaagaagcga ttggagcaaa caacagcagg
     2341 actacctcac acagctcagc gaccttgaga agcagctcca ggatgcgcag actaagaatg
     2401 actttttgaa atgtgaggta catgacctgc gaattgttct taattctgct gacaaagaac
     2461 tttctttggt gaaactggag tatagcacat tcaaagagag tcaagagaaa gaactaagcc
     2521 agctttctga cagacatgtg caggttcagc ttcagctgga caatgccaga ttagaaaatg
     2581 aaaaacttct tgagagccaa gcctgtctac aggattccta cgataactta caagaagtaa
     2641 tgaaattcga agttgaccaa ctttcaaaaa acctccaaaa ctgcaaacaa gagaatgaaa
     2701 ctttaaagtc tgatctgcat aacttggtgg agctttttga ggcagaaaaa gagcgcaaca
     2761 acaaattgtc actacagttt gaagaagata aagaaaacag ctctaaagaa atcttaaagg
     2821 ctcttgaaac tgtacgtcag gaaaaacagg aagagatggc cagatgtgaa aagcagatgg
     2881 caaaggtaca ggaactagaa gaaagcttgc ttgctgctga aaatgttgtc agctgtctgg
     2941 agaagtctag ggagtctgac aaggaacttg tcaccaacct catgaaccaa atccaggagt
     3001 taagaacatc agctggtgaa aaatcagaag ccatagacac cctgaaacaa gagctgcaag
     3061 acataagttg caaatacact gctgctgtgg ctgacaaaga agagagcaag gagttgatca
     3121 ggagacagga agtggatatc ctggaactga aagaaactct tagactgaga attctctcag
     3181 aggacatcga gagggatatg ctgtgtgaag atctggccca tgccactgag cagctgaaca
     3241 tgctcacaga ggcctccaaa aagcactctg gactactgca gtctgcccag gaagagctga
     3301 ccaagaagga ggctctgatc caggaacttc agcacaagtt aaaccaggag aaggaggaag
     3361 tggagcagaa gaagagtgag tacaacttga agatgaagca gctggagcac gtgatgggct
     3421 ctgctcctga gtatccacag agtccaaaaa caccacccca ttttcaaact catttggcaa
     3481 aactcttgga aacacaagaa caagagatag aagacggaag ggcatctaag atgtctttgc
     3541 aacacctcgt cacaaagcta aacgaagaca gagaagtcaa aaacgctgag atcctcagga
     3601 tgaaggatca gttgtgtgaa atggaaaatc tgcgcctgga gtctcagcag ttgagagaga
     3661 gaacctggct cctgcagact cagctggatg atatgaagag gcagggggag agcagcagtc
     3721 agagtcgtcc agacagccaa cagctgaaga atgaatatga agaggagatt atcagagaga
     3781 gacttgctaa aaataaactt attgaagaaa tgctaaaaat gaaaacagat ctagaggaag
     3841 tccagagtgc acttgacagc aaggagaagt tctgccacag aatgagcgag gaagttgagc
     3901 gaaccagaac tttggagtcc agagcatttc aggaaaagga gcaattgcgg tcaaagttgg
     3961 aagaaatgta tgaagagaga gagagaactt gccaggaaat ggaaatgctg agaaaacaac
     4021 tagagtttct tgctgaggaa aatgggaaat tgataggtca tcaaaaccta catcagaaga
     4081 ttcaatatgt agtgcgactg aagaaggaaa atatcaggct tgctgaggag acagaaaaat
     4141 tgcgtgctga aaatgtattt ttgaaagaaa ggaaaaaaga atgaatccta aggatgcccg
     4201 ctgtcttcct acac
//
