LOCUS       NM_133318               1963 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus KH RNA binding domain containing, signal
            transduction associated 2 (Khdrbs2), mRNA.
ACCESSION   NM_133318
VERSION     NM_133318.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1963)
  AUTHORS   Iijima,T., Wu,K., Witte,H., Hanno-Iijima,Y., Glatter,T., Richard,S.
            and Scheiffele,P.
  TITLE     SAM68 regulates neuronal activity-dependent alternative splicing of
            neurexin-1
  JOURNAL   Cell 147 (7), 1601-1614 (2011)
   PUBMED   22196734
REFERENCE   2  (bases 1 to 1963)
  AUTHORS   Yu,H., Tardivo,L., Tam,S., Weiner,E., Gebreab,F., Fan,C.,
            Svrzikapa,N., Hirozane-Kishikawa,T., Rietman,E., Yang,X.,
            Sahalie,J., Salehi-Ashtiani,K., Hao,T., Cusick,M.E., Hill,D.E.,
            Roth,F.P., Braun,P. and Vidal,M.
  TITLE     Next-generation sequencing to generate interactome datasets
  JOURNAL   Nat Methods 8 (6), 478-480 (2011)
   PUBMED   21516116
REFERENCE   3  (bases 1 to 1963)
  AUTHORS   Heinrich,B., Zhang,Z., Raitskin,O., Hiller,M., Benderska,N.,
            Hartmann,A.M., Bracco,L., Elliott,D., Ben-Ari,S., Soreq,H.,
            Sperling,J., Sperling,R. and Stamm,S.
  TITLE     Heterogeneous nuclear ribonucleoprotein G regulates splice site
            selection by binding to CC(A/C)-rich regions in pre-mRNA
  JOURNAL   J Biol Chem 284 (21), 14303-14315 (2009)
   PUBMED   19282290
REFERENCE   4  (bases 1 to 1963)
  AUTHORS   Stoss,O., Novoyatleva,T., Gencheva,M., Olbrich,M., Benderska,N. and
            Stamm,S.
  TITLE     p59(fyn)-mediated phosphorylation regulates the activity of the
            tissue-specific splicing factor rSLM-1
  JOURNAL   Mol Cell Neurosci 27 (1), 8-21 (2004)
   PUBMED   15345239
  REMARK    GeneRIF: SLM-1 is a tissue-specific splicing factor whose activity
            is regulated by tyrosine phosphorylation signals emanating from
            p59(fyn).
REFERENCE   5  (bases 1 to 1963)
  AUTHORS   Di Fruscio,M., Chen,T. and Richard,S.
  TITLE     Characterization of Sam68-like mammalian proteins SLM-1 and SLM-2:
            SLM-1 is a Src substrate during mitosis
  JOURNAL   Proc Natl Acad Sci U S A 96 (6), 2710-2715 (1999)
   PUBMED   10077576
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Nov 26, 2020 this sequence version replaced NM_133318.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF305618.1, SRR26360176.2157540.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760433
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-242               JAXUCZ010000009.1  41943070-41943311
            243-370             JAXUCZ010000009.1  42014254-42014381
            371-487             JAXUCZ010000009.1  42091843-42091959
            488-634             JAXUCZ010000009.1  42155654-42155800
            635-762             JAXUCZ010000009.1  42228273-42228400
            763-961             JAXUCZ010000009.1  42231334-42231532
            962-1044            JAXUCZ010000009.1  42362668-42362750
            1045-1103           JAXUCZ010000009.1  42395819-42395877
            1104-1963           JAXUCZ010000009.1  42410686-42411545
FEATURES             Location/Qualifiers
     source          1..1963
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q21"
     gene            1..1963
                     /gene="Khdrbs2"
                     /gene_synonym="Slm1"
                     /note="KH RNA binding domain containing, signal
                     transduction associated 2"
                     /db_xref="GeneID:170843"
                     /db_xref="RGD:621738"
     exon            1..242
                     /gene="Khdrbs2"
                     /gene_synonym="Slm1"
                     /inference="alignment:Splign:2.1.0"
     CDS             152..1201
                     /gene="Khdrbs2"
                     /gene_synonym="Slm1"
                     /note="SLM-1; rSLM-1; Sam68-like mammalian protein 1; KH
                     domain containing, RNA binding, signal transduction
                     associated 2"
                     /codon_start=1
                     /product="KH domain-containing, RNA-binding, signal
                     transduction-associated protein 2"
                     /protein_id="NP_579852.1"
                     /db_xref="GeneID:170843"
                     /db_xref="RGD:621738"
                     /translation="MGEEKYLPELMAEKDSLDPSFVHASRLLAEEIEKFQGSDGRKED
                     EEKKYLDVISNKNIKLSERVLIPVKQYPKFNFVGKLLGPRGNSLKRLQEETGAKMSIL
                     GKGSMRDKAKEEELRKSGEAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIKKFLV
                     PDYNDEIRQEQLRELSYLNGSEESGRGRGIRGRGIRITPTAPSRGRGGAVPPPPPPGR
                     GVLTPRGTTVTRGALPVPPVARGVPTPRARGTAAVPGYRAPPPPAPEAYEEYGYDDGY
                     GGEYDDQTYEAYDNSYVTPTQSVPEYYDYGHGVNEDAYDSYAPEEWTTTRSSLKAPPP
                     RSARGGYREHPYGRY"
     exon            243..370
                     /gene="Khdrbs2"
                     /gene_synonym="Slm1"
                     /inference="alignment:Splign:2.1.0"
     exon            371..487
                     /gene="Khdrbs2"
                     /gene_synonym="Slm1"
                     /inference="alignment:Splign:2.1.0"
     exon            488..634
                     /gene="Khdrbs2"
                     /gene_synonym="Slm1"
                     /inference="alignment:Splign:2.1.0"
     exon            635..762
                     /gene="Khdrbs2"
                     /gene_synonym="Slm1"
                     /inference="alignment:Splign:2.1.0"
     exon            763..961
                     /gene="Khdrbs2"
                     /gene_synonym="Slm1"
                     /inference="alignment:Splign:2.1.0"
     exon            962..1044
                     /gene="Khdrbs2"
                     /gene_synonym="Slm1"
                     /inference="alignment:Splign:2.1.0"
     exon            1045..1103
                     /gene="Khdrbs2"
                     /gene_synonym="Slm1"
                     /inference="alignment:Splign:2.1.0"
     exon            1104..1963
                     /gene="Khdrbs2"
                     /gene_synonym="Slm1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgggagagg caggtaccag cgcggtctgc gcagcccgag gcgctagagc tgcgctcacc
       61 gcaggaagga cggttcctgg gggaaccagg gaccgaggcg tccgagcagg cgggatttgc
      121 gcctggccgg ccacggtccg aagtccgcgc tatgggagaa gagaaatact tgcctgagct
      181 gatggcagag aaggatagcc ttgatccatc ttttgtgcac gcgtcgcgcc ttctggcgga
      241 agaaattgag aaattccaag gctcggatgg aagaaaagaa gatgaggaaa agaagtatct
      301 cgatgtcatc agcaacaaaa acataaagct ctcggaaagg gtattgatcc ccgtgaaaca
      361 gtatccaaag ttcaattttg tggggaaatt gcttggacca agaggaaact ccttgaagag
      421 gctacaagaa gaaacgggtg ctaaaatgtc tatcctgggc aaaggatcga tgcgtgacaa
      481 ggcaaaggaa gaagagctga ggaagagtgg ggaggccaag tatgcccacc tgagtgacga
      541 actgcacgta ttaattgaag tgtttgctcc acccggggaa gcttactcac ggatgagtca
      601 tgctttggaa gagattaaaa aattcctggt tcctgactac aatgatgaaa ttcgtcaaga
      661 gcaactccgg gagttgtctt acttgaatgg ctcagaagag tctggccggg gccgaggtat
      721 tagaggcaga gggatcagaa taactcccac agctccttca aggggccgtg ggggtgctgt
      781 tccaccacca ccaccacctg gacgaggtgt tcttacccct cggggaacca ctgtgacccg
      841 cggagctctc ccagtacccc cagtagcaag aggtgtccca acacctcgag cccggggaac
      901 agcagcggtc ccaggataca gagcgccccc acctccagct cctgaggctt atgaagagta
      961 tgggtacgat gatggctatg ggggtgaata tgatgaccag acctatgagg cttatgataa
     1021 tagctacgtg accccgacac aaagtgtgcc tgaatactat gactatggtc atggagtaaa
     1081 tgaggatgcc tatgacagct acgcaccaga agaatggacc acaacccgct ccagcctgaa
     1141 ggcaccacca ccaaggtcag ccagaggggg atacagggaa cacccctatg gtagatattg
     1201 aaggtcctct tcacctgtga cctcctcaaa gacaattcat agcctgtgct cttcacataa
     1261 acagcaacaa gacaagtaat agtctttttt gtttgtttgt tttttctatc ctagggataa
     1321 ctgctcataa ttactcccac ctattcttgt attctcttat actgttaacg tgacatggac
     1381 attagtatta ttttataaaa cagactggaa aaaaaagaga ctggcaagca tagtttataa
     1441 accattctgt aggttgatat tctcttgatt gttttttttt ttaattgttg tgtgtaaacc
     1501 gccaacccct tccctttcct tttcggtttc ctttctcctt tttcttttgt agaaaaaaaa
     1561 agagcatgaa cctgttagat tttgagtctc aaccaactag ccgaaccttt gtttagggtt
     1621 gttaaaagac tgtaatatga ttttgaacta gctgataaca cagttgtaga taagatgttt
     1681 taacctgtct tttaatatct gttagtcaga tggagatgtt caatattaag ttgtaaattt
     1741 aatttttaaa tgctgtttta atggggtgga aaacaagcag ctactgtatg tatgtagcta
     1801 actgaatttg ttcagtgttt taacctgtat ttgttaaaaa aagaaaaaag aaaaaaacac
     1861 acatgaagtt ccatgtgtaa gcttctctaa ataggaacca caatttgtca aatatgtttg
     1921 ccataatttg tcaataaagc tgaaggcttt tgtaaaaact aaa
//
