LOCUS       XM_039100359            5609 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus lysine demethylase 6A (Kdm6a),
            transcript variant X1, mRNA.
ACCESSION   XM_039100359
VERSION     XM_039100359.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051356.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039100359.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5609
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..5609
                     /gene="Kdm6a"
                     /note="lysine demethylase 6A; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 24
                     ESTs, 1 long SRA read, 7 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 59 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:103689969"
                     /db_xref="RGD:9275041"
     CDS             391..4818
                     /gene="Kdm6a"
                     /codon_start=1
                     /product="lysine-specific demethylase 6A isoform X1"
                     /protein_id="XP_038956287.1"
                     /db_xref="GeneID:103689969"
                     /db_xref="RGD:9275041"
                     /translation="MKSCGVSLATAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEE
                     REALGGLDSRLFGFVRFHEDGARMKALLGKAVRCYESLILKAEGKVESDFFCQLGHFN
                     LLLEEYPKALSAYQRYYSLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDP
                     SFCRAKEIHLRLGLMFKVNTDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQR
                     KYHSAKEAYEQLLQLENLSAQVKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSL
                     EADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPM
                     DALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNATRSKNCSNTSGLAAR
                     IKYLQAQLCNLPQGSLQNKTKLLPSIEEAWSLPIPAELTSRQGAMNTAQQACKPHHPN
                     TEPVLGLSQTPISQQSLPLHMIPPSQVDDLSSPAKRKRTSSPTKNTSDNWSGGNAVPH
                     PPVQQQTHSWCLTPQKLQHLEQLRANRNNLNPAQKLMLEQLESQFVLMQQHQMRQTGV
                     AQVRPTGIPNGPTADSSLPTNSASGQQPQLPLTRMPSVSQPGVQPACPRQALANGPFS
                     AGHVPCSTSRTLGSTDTILIGNNHVTGSGSNGNVPYLQRNAPTLPHNRTNLTSSTEEP
                     WKNQLSNSTQGLHKGQSSHLAGPNGERPLSSTGPSQHLQAAGSGIQNQNGHPTLPSNS
                     VTQGAALNHLSSHTATSGGQQGITLTKESKPSGNTLTLPETNRQTGETPNSTASVEGL
                     PNHVHQVMADAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGPGTCDIVNNIHP
                     TVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQ
                     SPIKTDLLLVSHRPSPQIIPSVSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPP
                     RPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKL
                     DLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKIWHCESNRSHTTIAKYAQ
                     YQASSFQESLREENEKRSHHKDHSDSESTSSDNSGKRRRGPFKTIKFGTNIDLSDDKK
                     WKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFC
                     SVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDLYEANVPVYRFI
                     QRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNKLQSVKSIVP
                     MVHLSWNMARNIKVSDPKLFEMVKYCLLRTLKQCQTLREALIAAGKEIIWHGRTKEEP
                     AHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCAWKTSGNLENFVVLEQYKMEDLMQ
                     VYDQFTLVSEINMLLHYHPPHLDIVPWTLNMRPFLLFRK"
ORIGIN      
        1 cggcgtgggg tttgctgtgt gacacaatta caacaacttt gtgctggtgc cggggaagtt
       61 tgtgtctcct acgaatcccc ccggagatcc cgctcctcgc gcgctccggc cattcccgtc
      121 gtccctgcct gtggctgtcc ccttcccacc cccgcgatgt gaccctacag ccgagtcgtc
      181 gctgctcccg acccagtggc tccacagcct gtgcggccgc tgccttcacc tctaccgcgt
      241 taggattttt cgccgccgcc tctcgcggca gaggaggagg cagagataaa gttggtgtgc
      301 cggtcccgtg cggagattga aagcgtcctt gcgggctccg gtccggggag gggggtgtcg
      361 gcgttggagt tgtgaattcg ctacgtttcc atgaaatcct gcggagtgtc gctcgctact
      421 gccgccgccg ccgccgcttt cggtgatgag gaaaagaaaa tggcggcggg aaaagcgagc
      481 ggcgagagcg aggaggcgtc ccctagcctg acagccgaag agagggaggc gctcggtgga
      541 ctggacagcc gccttttcgg gttcgtgagg tttcatgaag atggcgccag gatgaaggcc
      601 ctgctgggca aggctgttcg ctgctacgaa tctctgatct taaaagctga aggaaaagtg
      661 gagtctgatt tcttttgtca attaggtcac ttcaacctct tattggaaga gtatccaaaa
      721 gcattatctg cataccagag gtactacagt ttacagtctg actactggaa gaatgctgcc
      781 tttttatatg gtcttggttt ggtctacttc cattacaatg catttcagtg ggctattaaa
      841 gcatttcagg aggtgcttta tgttgatccc agcttttgtc gagccaagga aattcattta
      901 cgacttgggc ttatgttcaa agtgaataca gactatgagt ctagtttaaa gcattttcag
      961 ttagctttgg ttgactgcaa tccctgcact ttgtccaatg ctgaaattca gtttcacatt
     1021 gcccacttat atgaaaccca gaggaagtat cattctgcaa aagaagctta tgagcaactt
     1081 ttgcagctag aaaacctttc tgcacaagta aaagcaactg tcttacaaca attaggttgg
     1141 atgcatcaca ctgtggatct cctaggagat aaggccacca aggaaagtta tgctattcaa
     1201 tatctccaga agtccttgga agcagatcca aattctggcc agtcctggta tttccttgga
     1261 aggtgctatt caagtattgg gaaagttcag gatgccttta tatcttacag gcaatctatt
     1321 gataaatctg aagcaagtgc agatacatgg tgttcaatag gtgtgctcta tcaacagcaa
     1381 aatcagccta tggatgcttt acaagcttat atttgtgctg tacaattgga ccatggccat
     1441 gctgcagcct ggatggatct aggcactctc tatgaatcct gcaaccagcc tcaagatgct
     1501 attaaatgct atttaaatgc aactagaagc aaaaattgta gtaatacctc tggacttgca
     1561 gcacgaatta aatatttaca ggctcagttg tgtaaccttc cacaaggtag tctacagaat
     1621 aaaactaaat tacttcctag tattgaggag gcatggagcc taccaattcc cgcagagctt
     1681 acctccaggc agggtgccat gaacacagca cagcaggcat gtaaacctca tcatccaaat
     1741 actgaacctg tattaggcct cagtcaaaca ccaatttcac agcagtcctt gccactacac
     1801 atgattcctc ctagccaagt agatgacctg tccagtcctg ccaagaggaa aagaacatct
     1861 agtccaacaa agaatacttc tgataattgg agtggtggca atgctgtgcc acatcctcca
     1921 gtacaacaac aaactcattc atggtgtttg acaccacaga aattacagca cttggagcag
     1981 ctccgagcaa atagaaataa tttaaatcca gcacagaaac taatgctgga acagctggaa
     2041 agtcagtttg tcttaatgca gcaacaccaa atgagacaaa caggagttgc acaggttcgg
     2101 cctactggaa ttcctaatgg gccaacagct gactcatcac tgcctacaaa ttcagcttct
     2161 ggccagcagc cacagcttcc tttgaccaga atgcctagtg tctctcagcc tggagtccaa
     2221 cctgcctgtc ccagacaggc tttggccaat ggaccctttt ctgcaggcca tgttccctgt
     2281 agcacatcaa gaacactggg aagtacagac actattttga taggcaataa tcatgtaaca
     2341 ggaagtggaa gtaatggaaa cgtgccttac ctgcagcgaa acgcacccac tctacctcat
     2401 aaccgcacaa acctgaccag cagcacagag gagccgtgga aaaaccaact atctaactcc
     2461 actcaggggc ttcacaaagg tcagagttca catttggcag gtcctaatgg tgaacgacct
     2521 ctttcttcca ctgggccttc ccagcatctc caggcagctg gctctggtat tcagaatcag
     2581 aatggacatc ccaccctgcc tagcaattca gtaacacagg gggctgctct caatcacctc
     2641 tcctctcaca ctgctacctc aggtggacaa caaggcatta ccttaaccaa agagagcaag
     2701 ccttcaggaa acacattgac actgcctgaa acaaacaggc aaactggaga gacacctaac
     2761 agcactgcca gtgttgaggg acttcctaat catgtccatc aggtgatggc agatgctgtt
     2821 tgcagtccta gccatggaga ttctaagtca ccaggtttac taagttcaga caatcctcag
     2881 ctctctgcct tgttgatggg aaaagctaat aacaatgtgg gtcctggaac ctgtgacata
     2941 gtcaataaca tccacccaac tgtccataca aagactgata attctgttgc ctcttcacca
     3001 tcttcagcca tttccacagc aacaccttct cctaaatcca ctgagcagac aaccacaaac
     3061 agtgttacca gccttaacag ccctcacagt gggctgcaca caattaatgg agaaggaatg
     3121 gaagaatctc agagccccat caaaacagat ctgcttctag ttagccacag acccagtcct
     3181 cagatcatac catcagtgtc tgtgtctata tatcccagct cagcagaagt tctgaaagct
     3241 tgcaggaatc taggtaaaaa tggcctgtct aatagtagca ttctgttgga taaatgtcca
     3301 cctccaagac caccatcctc accatatcct cccttgccaa aggacaagtt gaatccacct
     3361 acacctagta tttatttgga aaataaacgt gatgctttct ttccaccatt acatcaattt
     3421 tgtacaaatc caaacaaccc tgttacagta attcgtggcc ttgctggagc tcttaaatta
     3481 gacttgggac ttttctctac taaaactttg gtggaagcta acaatgaaca tatggtagaa
     3541 gtgaggacac agttgttaca accagcagat gaaaattggg accctactgg aaccaagaaa
     3601 atctggcact gtgaaagcaa tagatctcat actacaattg ctaaatatgc tcagtaccag
     3661 gcctcctcgt tccaagaatc attgagagaa gaaaatgaga aaagaagtca ccataaagac
     3721 cactcggaca gtgaatctac atcatcagat aattctggga aaaggagaag gggacccttt
     3781 aaaaccatta agtttgggac caacattgac ctgtctgatg acaaaaagtg gaagttacag
     3841 ctacatgagc tgactaaact tcctgccttt gtgagagttg tatcagcagg aaatcttcta
     3901 agccatgttg gtcatactat actgggcatg aacacagttc aactatacat gaaagttcca
     3961 ggaagcagaa caccaggtca tcaagaaaat aacaacttct gttcagttaa tataaatatt
     4021 ggcccaggtg actgtgaatg gtttgttgtt cctgaaggct actggggtgt tctgaacgac
     4081 ttctgtgaaa aaaataattt gaatttctta atgggttctt ggtggcccaa ccttgaagat
     4141 ctttatgaag caaatgttcc agtatatagg tttattcagc gacctggaga tctggtctgg
     4201 ataaatgcag gaactgttca ttgggttcaa gctattggct ggtgcaacaa cattgcttgg
     4261 aatgttggtc cacttacagc ctgtcagtat aagttagcag tggaacggta tgaatggaac
     4321 aaattgcaaa gtgtaaagtc aatagtaccc atggttcatc tttcctggaa tatggcacga
     4381 aatatcaagg tttcagatcc aaagcttttt gaaatggtta agtattgtct tctgagaacc
     4441 ctgaagcaat gtcagacatt gagggaagct ttaattgctg caggaaaaga gatcatatgg
     4501 cacgggcgga caaaagaaga accagctcat tattgtagca tttgtgaggt ggaggttttt
     4561 gatctgcttt ttgtcactaa tgagagtaat tctcgaaaga cctacatagt acattgccaa
     4621 gattgtgcat ggaaaacaag tgggaatctg gaaaattttg tggtgctaga acagtacaaa
     4681 atggaggatc tgatgcaagt ctatgaccaa tttacattag taagtgaaat caacatgctc
     4741 ctccattacc atccgcctca tcttgatatt gttccatgga cattaaacat gagacctttt
     4801 ctgctattca ggaagtaacc cagttctgca ccactgcttt ttgtagctct ctcgtaaggc
     4861 tgctggctga aaactgtgtc tatgcaacct tccaagtgtg gagtatcaac caactggatg
     4921 ggagagtact gctcctatac caggactctc gtaaagctaa ttagctgaac ttcagaaaga
     4981 aagaataatt tccacgtttt gtatatatct gacaaaactg gcaacatcat acagactact
     5041 gacttgaaga caacctcttt tatatttctc gatttatggg ctaatgaatt tgttttcacc
     5101 tatcttttcc ctttcagaat tttccttggg ggaaaaaata ctagtcattt ctttgttaag
     5161 gtagttagca atattaagtc tttctttggt caactttttt ttttaatgtg aaaagttaag
     5221 taagaaactt ttttactgct tttatgattt tctgtcttgt tttgaaacca tgatggttat
     5281 acttttggtt cccaaataaa acatttaaag aaaaattaat taacagcaaa gtcacaaaga
     5341 taatggattg cacatatact aagaaataaa cttcaaattt gtgatttttt gtttctaatc
     5401 ttgatgtaaa tttacactat ttataaatac atatttattg cctgaaaata tttgtgaatg
     5461 gaatgccgtt attttttcca gatttacctg ccattgaaat tttaaggagt tctgtaattt
     5521 caaacactac tcctattaca ttttctatgt gtaaataaaa ctgcttagca ttgtacagaa
     5581 acttttatta aaattgttta atctttaaa
//
