LOCUS       NM_001108515            6807 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus lysine demethylase 2A (Kdm2a), mRNA.
ACCESSION   NM_001108515 XM_001068749 XM_341983
VERSION     NM_001108515.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6807)
  AUTHORS   Zuo,Y., Zhan,L., Wen,H., Xue,J., Tan,Y., Sun,W. and Xu,E.
  TITLE     Stabilization of nuclear beta-catenin by inhibiting KDM2A mediates
            cerebral ischemic tolerance
  JOURNAL   FASEB J 37 (3), e22796 (2023)
   PUBMED   36723950
  REMARK    GeneRIF: Stabilization of nuclear beta-catenin by inhibiting KDM2A
            mediates cerebral ischemic tolerance.
REFERENCE   2  (bases 1 to 6807)
  AUTHORS   Xu,C., Liu,K., Lei,M., Yang,A., Li,Y., Hughes,T.R. and Min,J.
  TITLE     DNA Sequence Recognition of Human CXXC Domains and Their Structural
            Determinants
  JOURNAL   Structure 26 (1), 85-95 (2018)
   PUBMED   29276034
REFERENCE   3  (bases 1 to 6807)
  AUTHORS   Tumber,A., Nuzzi,A., Hookway,E.S., Hatch,S.B., Velupillai,S.,
            Johansson,C., Kawamura,A., Savitsky,P., Yapp,C., Szykowska,A.,
            Wu,N., Bountra,C., Strain-Damerell,C., Burgess-Brown,N.A.,
            Ruda,G.F., Fedorov,O., Munro,S., England,K.S., Nowak,R.P.,
            Schofield,C.J., La Thangue,N.B., Pawlyn,C., Davies,F., Morgan,G.,
            Athanasou,N., Muller,S., Oppermann,U. and Brennan,P.E.
  TITLE     Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of
            H3K4me3 at Transcription Start Sites and Proliferation of MM1S
            Myeloma Cells
  JOURNAL   Cell Chem Biol 24 (3), 371-380 (2017)
   PUBMED   28262558
REFERENCE   4  (bases 1 to 6807)
  AUTHORS   Reischl,S. and Kramer,A.
  TITLE     Fbxl11 Is a Novel Negative Element of the Mammalian Circadian Clock
  JOURNAL   J Biol Rhythms 30 (4), 291-301 (2015)
   PUBMED   26037310
REFERENCE   5  (bases 1 to 6807)
  AUTHORS   Kawakami,E., Tokunaga,A., Ozawa,M., Sakamoto,R. and Yoshida,N.
  TITLE     The histone demethylase Fbxl11/Kdm2a plays an essential role in
            embryonic development by repressing cell-cycle regulators
  JOURNAL   Mech Dev 135, 31-42 (2015)
   PUBMED   25463925
REFERENCE   6  (bases 1 to 6807)
  AUTHORS   Wagner,K.W., Alam,H., Dhar,S.S., Giri,U., Li,N., Wei,Y., Giri,D.,
            Cascone,T., Kim,J.H., Ye,Y., Multani,A.S., Chan,C.H., Erez,B.,
            Saigal,B., Chung,J., Lin,H.K., Wu,X., Hung,M.C., Heymach,J.V. and
            Lee,M.G.
  TITLE     KDM2A promotes lung tumorigenesis by epigenetically enhancing
            ERK1/2 signaling
  JOURNAL   J Clin Invest 123 (12), 5231-5246 (2013)
   PUBMED   24200691
REFERENCE   7  (bases 1 to 6807)
  AUTHORS   Long,H.K., Blackledge,N.P. and Klose,R.J.
  TITLE     ZF-CxxC domain-containing proteins, CpG islands and the chromatin
            connection
  JOURNAL   Biochem Soc Trans 41 (3), 727-740 (2013)
   PUBMED   23697932
  REMARK    Review article
REFERENCE   8  (bases 1 to 6807)
  AUTHORS   Black,J.C., Van Rechem,C. and Whetstine,J.R.
  TITLE     Histone lysine methylation dynamics: establishment, regulation, and
            biological impact
  JOURNAL   Mol Cell 48 (4), 491-507 (2012)
   PUBMED   23200123
  REMARK    Review article
REFERENCE   9  (bases 1 to 6807)
  AUTHORS   Fnu,S., Williamson,E.A., De Haro,L.P., Brenneman,M., Wray,J.,
            Shaheen,M., Radhakrishnan,K., Lee,S.H., Nickoloff,J.A. and
            Hromas,R.
  TITLE     Methylation of histone H3 lysine 36 enhances DNA repair by
            nonhomologous end-joining
  JOURNAL   Proc Natl Acad Sci U S A 108 (2), 540-545 (2011)
   PUBMED   21187428
REFERENCE   10 (bases 1 to 6807)
  AUTHORS   Blackledge,N.P., Zhou,J.C., Tolstorukov,M.Y., Farcas,A.M.,
            Park,P.J. and Klose,R.J.
  TITLE     CpG islands recruit a histone H3 lysine 36 demethylase
  JOURNAL   Mol Cell 38 (2), 179-190 (2010)
   PUBMED   20417597
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473953.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_341983.3, XM_001068749.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..6807
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..6807
                     /gene="Kdm2a"
                     /gene_synonym="Fbxl11"
                     /note="lysine demethylase 2A"
                     /db_xref="GeneID:361700"
                     /db_xref="RGD:1309419"
     exon            1..334
                     /gene="Kdm2a"
                     /gene_synonym="Fbxl11"
                     /inference="alignment:Splign:2.1.0"
     exon            335..429
                     /gene="Kdm2a"
                     /gene_synonym="Fbxl11"
                     /inference="alignment:Splign:2.1.0"
     CDS             388..3873
                     /gene="Kdm2a"
                     /gene_synonym="Fbxl11"
                     /EC_number="1.14.11.27"
                     /note="F-box and leucine-rich repeat protein 11; lysine
                     (K)-specific demethylase 2A"
                     /codon_start=1
                     /product="lysine-specific demethylase 2A"
                     /protein_id="NP_001101985.1"
                     /db_xref="GeneID:361700"
                     /db_xref="RGD:1309419"
                     /translation="MEPEEERIRYSQRLRGTMRRRYEDDGISDDEIEGKRTFDLEEKL
                     HTNKYNANFVTFMEGKDFNVEYIQRGGLRDPLIFKNSDGLGIKMPDPDFTVNDVKMCV
                     GSRRMVDVMDVNTQKGIEMTMAQWTRYYETPEEEREKLYNVISLEFSHTRLENMVQRP
                     STVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGT
                     SVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTF
                     VIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCW
                     YVLERYVYCITNRSHLTKEFQKESLSMDMELNELESGNGDEEGADKEARRMNSKRSVL
                     TSPVANGVNLDYDGLGKACRSLPNLKKTLSGDSSSDSSRGSHNGQVWDPQCSPRKDRQ
                     VHLTHFELEGLRCLVDKLESLPLHKKCVPTGIEDEDALIADVKILLEELASSDPKLAL
                     TGVPIVQWPKRDKLKFPTRPKVRVPTIPITKPHTMKPAPRLTPVRPAAASPIVSGARR
                     RRVRCRKCKACVQGECGVCHYCRDMKKFGGPGRMKQSCVLRQCLAPRLPHSVTCSLCG
                     EVDQNEETQDFEKKLMECCICNEIVHPGCLQMDGEGLLNEELPNCWECPKCYQEDSSE
                     KAQKRKIEESDEEAVQAKVLRPLRSCEEPLTPPPHSPTSMLQLIHDPVSPRGMVTRSS
                     PGAGPSDHHSASRDERFKRRQLLRLQATERTMVREKENNPSGKKELSEVEKAKIRGSY
                     LTVTLQRPTKELHGTSIVPKLQAITASSANLRPNPRVLMQHCPARNPQRGDEEGLGGE
                     EEEEEEEEEDDSAEEGGAARLNGRGSWAQDGDESWMQREVWMSVFRYLSRRELCECMR
                     VCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSGIIKRQPVSLDLSWTNISKKQLTWLV
                     NRLPGLKDLLLAGCSWSAVSALSTSSCPLLRTLDLRWAVGIKDPQIRDLLTPPTDKPG
                     QDNRSKLRNMTDFRLAGLDITDATLRLIIRHMPLLSRLDLSHCSHLTDQSSNLLTAVG
                     SSTRYSLTELNMAGCNKLTDQTLFFLRRIANVTLIDLRGCKQITRKACEHFISDLSIN
                     SLYCLSDEKLIQKIS"
     exon            430..568
                     /gene="Kdm2a"
                     /gene_synonym="Fbxl11"
                     /inference="alignment:Splign:2.1.0"
     exon            569..647
                     /gene="Kdm2a"
                     /gene_synonym="Fbxl11"
                     /inference="alignment:Splign:2.1.0"
     exon            648..694
                     /gene="Kdm2a"
                     /gene_synonym="Fbxl11"
                     /inference="alignment:Splign:2.1.0"
     exon            695..873
                     /gene="Kdm2a"
                     /gene_synonym="Fbxl11"
                     /inference="alignment:Splign:2.1.0"
     exon            874..980
                     /gene="Kdm2a"
                     /gene_synonym="Fbxl11"
                     /inference="alignment:Splign:2.1.0"
     exon            981..1074
                     /gene="Kdm2a"
                     /gene_synonym="Fbxl11"
                     /inference="alignment:Splign:2.1.0"
     exon            1075..1228
                     /gene="Kdm2a"
                     /gene_synonym="Fbxl11"
                     /inference="alignment:Splign:2.1.0"
     exon            1229..1344
                     /gene="Kdm2a"
                     /gene_synonym="Fbxl11"
                     /inference="alignment:Splign:2.1.0"
     exon            1345..1471
                     /gene="Kdm2a"
                     /gene_synonym="Fbxl11"
                     /inference="alignment:Splign:2.1.0"
     exon            1472..1866
                     /gene="Kdm2a"
                     /gene_synonym="Fbxl11"
                     /inference="alignment:Splign:2.1.0"
     exon            1867..1950
                     /gene="Kdm2a"
                     /gene_synonym="Fbxl11"
                     /inference="alignment:Splign:2.1.0"
     exon            1951..2220
                     /gene="Kdm2a"
                     /gene_synonym="Fbxl11"
                     /inference="alignment:Splign:2.1.0"
     exon            2221..2352
                     /gene="Kdm2a"
                     /gene_synonym="Fbxl11"
                     /inference="alignment:Splign:2.1.0"
     exon            2353..2442
                     /gene="Kdm2a"
                     /gene_synonym="Fbxl11"
                     /inference="alignment:Splign:2.1.0"
     exon            2443..3152
                     /gene="Kdm2a"
                     /gene_synonym="Fbxl11"
                     /inference="alignment:Splign:2.1.0"
     exon            3153..3316
                     /gene="Kdm2a"
                     /gene_synonym="Fbxl11"
                     /inference="alignment:Splign:2.1.0"
     exon            3317..3475
                     /gene="Kdm2a"
                     /gene_synonym="Fbxl11"
                     /inference="alignment:Splign:2.1.0"
     exon            3476..3691
                     /gene="Kdm2a"
                     /gene_synonym="Fbxl11"
                     /inference="alignment:Splign:2.1.0"
     exon            3692..6807
                     /gene="Kdm2a"
                     /gene_synonym="Fbxl11"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggcttcgga agcggctgtg accgtctgag ggtaccgaga agagggtgtt tcccgcggcc
       61 gggttggccc gggtttcggg ctggggctgc tgaccgccag cttgggggag tagccgagtg
      121 gtcttgctat cctgacgcct cagacgcgga gtctgtaaag ccagaagagg aggtttggtt
      181 cagtcactgt ttcctctttt ccgggtcgct ctgacccttc tctggatact gggttaatac
      241 acagaaatac cgaagacgac gtttgggatt ttattttttc tctgtttgga attttacttc
      301 tctcttggac aagaactcaa gaacaaaatc ctcggaagag gaaggcatcc gggagtggtt
      361 tctgtacttc catcagaaga gtaagagatg gaacctgaag aagaaaggat tcggtacagc
      421 cagagattgc gtggtaccat gcgacgtcgc tatgaagatg atggcatttc agatgatgaa
      481 attgaaggga aaagaacttt tgacttggaa gagaagctcc ataccaacaa atataatgcc
      541 aattttgtta cttttatgga gggaaaagat tttaatgtag agtatatcca gcggggtggc
      601 ttgagagacc ctctcatttt caagaattct gatggacttg gaataaagat gccggatcca
      661 gacttcacag tgaatgatgt caaaatgtgt gtggggagtc gtcggatggt ggatgtcatg
      721 gacgtgaaca cacagaaggg gattgaaatg accatggcgc aatggacacg atactatgag
      781 actccagagg aagagcgaga gaaactctat aatgttatca gcctagagtt tagccacacc
      841 aggcttgaga atatggtaca gcggccttcc acggtggatt tcattgactg ggtagataac
      901 atgtggccaa ggcacttgaa agaaagtcag actgaatcaa caaatgccat cttagagatg
      961 cagtacccta aagtgcaaaa gtactgtcta atgagtgttc gaggctgcta tactgacttc
     1021 catgtggatt ttggaggtac ttctgtttgg tatcacatcc accaaggtgg aaaggtcttc
     1081 tggctcatcc cccctacagc ccacaacctg gagctgtacg agaattggct gctatcaggg
     1141 aaacagggag acatctttct gggtgaccgg gtgtcagatt gccaacgaat tgagctcaag
     1201 cagggctata ccttcgttat tccctcaggt tggattcatg ctgtgtatac tcctacggac
     1261 acattagtgt ttggaggcaa ttttttgcat agctttaaca tccccatgca attaaagata
     1321 tatagtattg aagatcgaac acgggttcca aataaattcc gttacccatt ttactatgaa
     1381 atgtgttggt atgtgttgga gcgctatgta tactgcataa ccaaccgatc tcacctaact
     1441 aaggaatttc agaaagaatc ccttagcatg gatatggaat taaatgagtt ggagtctgga
     1501 aatggtgatg aggaaggggc ggacaaagaa gcccgacgca tgaacagtaa gcgatctgtg
     1561 cttaccagcc ctgtggctaa tggagtcaac ctggattatg atggacttgg caaagcctgc
     1621 cgaagtcttc caaatctgaa gaaaactctg tctggagact catcctcaga ctctagtcgg
     1681 ggatcccaca atggccaagt ttgggatccc caatgtagcc ctagaaagga taggcaagtg
     1741 catctgaccc actttgaact tgaaggtctt cgatgtcttg tagataagtt agagtcactg
     1801 ccactgcaca agaagtgtgt ccccacaggg atagaagacg aagatgctct gattgctgat
     1861 gtaaagattt tgctggaaga acttgccagt agtgatccca agttagccct cactggagtt
     1921 cccatagtac agtggccaaa aagggataag cttaaatttc cgaccaggcc aaaggtgagg
     1981 gttcctacaa ttcccatcac aaagcctcac accatgaagc cggctccgcg cctaacacct
     2041 gtaaggcctg ctgcagcctc ccccattgtg tcaggagcca ggcggagaag agtgcgctgc
     2101 aggaaatgca aagcctgtgt gcaaggagaa tgtggagtct gccactactg cagggacatg
     2161 aagaaatttg gtgggcctgg acgcatgaag cagtcctgtg tcctcagaca gtgcttagca
     2221 cctagactgc ctcattcagt tacatgttct ctctgtggag aagtagatca gaatgaagag
     2281 acacaggact ttgaaaagaa actcatggaa tgctgcatct gcaacgagat agttcatcct
     2341 ggctgcctcc agatggatgg agaggggttg cttaacgagg aattgccaaa ttgctgggag
     2401 tgtccaaagt gttatcagga agacagctcg gagaaagccc agaagcggaa aatagaagag
     2461 agtgatgaag aagctgtaca agccaaagtc ctacggcccc tgaggagctg cgaggagcct
     2521 ctcacacccc cgcctcactc acctacttcc atgctgcagc tcatccacga cccggtttct
     2581 ccccggggta tggtgactcg gtcatcccct ggggctggcc ccagcgacca ccacagtgcc
     2641 agccgtgatg aacgcttcaa acggcggcag ttgctgcggc tacaagccac agagcgcacc
     2701 atggtacggg aaaaggagaa caatcccagc ggcaaaaagg agctgtctga agttgagaaa
     2761 gccaagatcc ggggatcgta cctcactgtc acgctacaga ggcccaccaa agagctccac
     2821 gggacatcca ttgtgcccaa gctgcaggcc atcacggcct cctctgccaa ccttcgccct
     2881 aacccccgtg tgctaatgca gcactgccca gcccggaacc cccagcgtgg ggatgaggag
     2941 gggcttgggg gagaggagga ggaagaggag gaggaggagg aagatgacag tgcagaggag
     3001 gggggtgcag caaggctgaa tggccggggc agttgggctc aggatggaga cgaaagctgg
     3061 atgcagcggg aggtctggat gtctgtcttc cgctacctca gccgcagaga actttgtgaa
     3121 tgtatgcgag tgtgcaagac gtggtataaa tggtgctgtg acaaacgact ttggacaaaa
     3181 attgacttga gtaggtgtaa ggccatcgtg ccccaggctc tcagtggcat catcaagcgg
     3241 cagccagtaa gcctggacct tagttggact aacatctcca aaaagcagct gacatggctg
     3301 gtcaataggc tgccaggatt aaaagacctc ctcctagcag gctgttcctg gtctgcagta
     3361 tctgccctca gcacctccag ctgccccctt ctcaggaccc ttgatcttcg gtgggcagta
     3421 ggaattaaag accctcaaat tcgggacttg ctgactccac ccacagataa gccaggtcaa
     3481 gacaatcgaa gcaaactccg gaacatgact gacttccggc tggcaggcct tgacatcacc
     3541 gatgccactc tccgactcat tattcgccac atgccccttt tgtctcgact tgacctcagt
     3601 cactgcagcc accttacaga tcagtcctcc aacctgctca ctgctgtcgg gtcttccact
     3661 cgatactccc ttacagagct caacatggcg ggttgcaata aactgacaga ccagaccctg
     3721 ttcttcctaa ggagaattgc taatgtcacc ttgattgacc ttcgaggatg caaacagatc
     3781 acaagaaaag cctgtgagca cttcatctca gacttgtcca tcaacagcct ctactgcctg
     3841 tctgatgaga aactgataca gaagattagc taagacatgc tcagcccaga ctgaacagga
     3901 aaatcttccc ctgccttccc atcaaggaga gtctctccct gacccttcgc aggctctgag
     3961 gccaacgaca cattccctct ctgctctctt tttctctgag cccttctccc acaggtgggg
     4021 cagagagagg ttggtggaca ccaaggttat tgcctgctcc tctccctccc aaggaaaaga
     4081 gaggagaggt tgatcaagga gaaagcacag gctgtgctat cccagtacct tgcttgcttg
     4141 ctcgtctgcc agctaggatg ctgggctctc agtttggggg aatttgtgca tctttcacct
     4201 gcactgggct aagaaccctc ccttctcacc catagtcccc agcagtgcct ggttctgagc
     4261 aaactctagg gagaatggcc agattctcct catggtgtcc gttgcgtgtc tctcctccgt
     4321 taaactctcc cggcttccgc aggaggagcc agcagcccta gaaacaccag gcctggcagg
     4381 tctcaatggt gctgtgagtt gtctgaagct ttgctccatg tctatgatag cccttttttc
     4441 ttgtccctga gcttgatgct gtccaacact cattcatata atcagtccct attctgccat
     4501 cactccgtaa tttttccact agtcaccggt gcacttgtcc attgttgcac ttacttgggg
     4561 ttatcaaagg ctcttcagag gagctgaact ctgccccagg aatccccatg tcattgctcc
     4621 ccaggcatat tctaaggcag gcatcattat cccccccacc acgcccccca cccctgttac
     4681 tgcccaccaa ttgccccttc ccatttgtcc tgtctcctgc gtaagcaggg cttttccaga
     4741 ttttgtgtcc tcagaaggag cagcatgttt ctccaggtgg gggaaacaga agactggtcg
     4801 aatccccacc ttcctccaag ccaggctttt ttgggctctg gtttagcatg gccctctgag
     4861 cccaggcctg tgtataacct agcagctcac tgacctggtg ccttttaagg ggagtcctga
     4921 ttgaaaacct accctctgcc tgcagccttg gaagtgtgtg tgcatgtgcc tgtgtgtctg
     4981 gctaagtgtg ctgcacatat gtgcagggaa ggagaggagc atgatgtctc ccactcctcc
     5041 attgcccctc ttcaagcccc atcagctgcc cccttttact ttgcattgaa cggcctgtcc
     5101 aaagatcctc tctctagggc agcagagagc tttttgcact ttaaagaaag aaagaaagaa
     5161 aatggtcgga actattctgg gtcaatattt agagtatgag gagatgctca gcagaggcct
     5221 gtggccagag tttgtcagtg atacatgcaa atttgcactc tgctccccat ctccccatag
     5281 gagattgata attgatagca cagccttgcc ccgccttctc ttaaccctaa acatacccct
     5341 tcccacccca tttcctgtaa tctagcctca gactttccta aactccatca ggaggggaca
     5401 gagcccgggc accatgagtc tgaagtgtga actgcccaag gagagatgct aactgtaccc
     5461 ttgccactgc caaagcaata gaggcagaag tgtcccctct gccacccgac ccagctttga
     5521 ccctggcaat aaccagactt tttccaggaa aactgggttt ctggcaaggg gtggtattgg
     5581 ttcttccaat ctgctgattt ctcttggctg caccttaaaa acagcagtct gctcccttga
     5641 ccctctgcca ttccattggt cttcaggtcc cagaattctg ggactgaaat gttgaggaaa
     5701 cgccagtgac ttattccaga gtgcctccgt taggggaact tctgtaaaga accctgggtg
     5761 ttgagcaaaa actttattaa tactattaat gacctataat tagaagcttc ctgacttttt
     5821 tttctttttg gttgctcctg tggaaaatac taaaattact aagttttgtt tgttgtcttt
     5881 ttatgaaagg ggaggtggag agaccctttc agagcaggga ttgtgccggg agagtgcctc
     5941 tgacctttgg gacagttcat ccacagaaat ttctaagctg atggcttgtc tgggttttgg
     6001 tctttgcatt tggatttcga gaaaacaagc attttactgc acagaaattt gtcagttgaa
     6061 aagggagctc aggatggtgg cagatggact gaagcccttg ctgggtctta cttttcttta
     6121 agactatgag ggagaatggt ttttagaggt gagagttggt ccttgcaaaa gagagaagtg
     6181 tctctgagga catagaacat gcagatctat agtcctgcac ctactcttag ctgtggtctt
     6241 gccagagcct ggcctcagac tgcaggacca gatctctgcc ttcatctttc cacatactgg
     6301 ggcaaaaaac cacaaaggaa aggaagaaaa ttatatatat ataattatat atatataata
     6361 taaaatcact tggtgattaa aaaaaataac tgctcaataa ataaaactcc taaagtcact
     6421 atgtttaaag ggtttggttt tttggggggg cgggaaatat tgtaaatata tattttttgt
     6481 tgcttattta gagtcgatct ccaatgttgt gctaagattt ttaaattaaa tgtaagcatt
     6541 aagggaatga gtcttaggcc accagctgac acattggcat tattttgggt cagggaagga
     6601 gaaagctagt tggactttgt tttctaaaag ttccccactt ggttttagaa agagcaaaga
     6661 tgtctttctt ctgacactcg ggaatgggag atatttgtgt aataaaattt ttaaaagaca
     6721 aaaaaagaaa tagcctccaa tgggaaatat tttgatttgg ttttcttttt tgtttttgtt
     6781 tttaaataaa aagactttaa aaacaaa
//
