LOCUS       NM_001017385            1476 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus KDEL endoplasmic reticulum protein retention
            receptor 1 (Kdelr1), mRNA.
ACCESSION   NM_001017385 XM_341860
VERSION     NM_001017385.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1476)
  AUTHORS   Siggs,O.M., Popkin,D.L., Krebs,P., Li,X., Tang,M., Zhan,X.,
            Zeng,M., Lin,P., Xia,Y., Oldstone,M.B., Cornall,R.J. and Beutler,B.
  TITLE     Mutation of the ER retention receptor KDELR1 leads to
            cell-intrinsic lymphopenia and a failure to control chronic viral
            infection
  JOURNAL   Proc Natl Acad Sci U S A 112 (42), E5706-E5714 (2015)
   PUBMED   26438836
REFERENCE   2  (bases 1 to 1476)
  AUTHORS   Rockich,B.E., Hrycaj,S.M., Shih,H.P., Nagy,M.S., Ferguson,M.A.,
            Kopp,J.L., Sander,M., Wellik,D.M. and Spence,J.R.
  TITLE     Sox9 plays multiple roles in the lung epithelium during branching
            morphogenesis
  JOURNAL   Proc Natl Acad Sci U S A 110 (47), E4456-E4464 (2013)
   PUBMED   24191021
REFERENCE   3  (bases 1 to 1476)
  AUTHORS   Valkova,C., Albrizio,M., Roder,I.V., Schwake,M., Betto,R.,
            Rudolf,R. and Kaether,C.
  TITLE     Sorting receptor Rer1 controls surface expression of muscle
            acetylcholine receptors by ER retention of unassembled
            alpha-subunits
  JOURNAL   Proc Natl Acad Sci U S A 108 (2), 621-625 (2011)
   PUBMED   21187406
REFERENCE   4  (bases 1 to 1476)
  AUTHORS   Rezvani,K., Teng,Y., Pan,Y., Dani,J.A., Lindstrom,J., Garcia
            Gras,E.A., McIntosh,J.M. and De Biasi,M.
  TITLE     UBXD4, a UBX-containing protein, regulates the cell surface number
            and stability of alpha3-containing nicotinic acetylcholine
            receptors
  JOURNAL   J Neurosci 29 (21), 6883-6896 (2009)
   PUBMED   19474315
REFERENCE   5  (bases 1 to 1476)
  AUTHORS   Raykhel,I., Alanen,H., Salo,K., Jurvansuu,J., Nguyen,V.D.,
            Latva-Ranta,M. and Ruddock,L.
  TITLE     A molecular specificity code for the three mammalian KDEL receptors
  JOURNAL   J Cell Biol 179 (6), 1193-1204 (2007)
   PUBMED   18086916
  REMARK    Erratum:[J Cell Biol. 2008 Feb 11;180(3):645]
REFERENCE   6  (bases 1 to 1476)
  AUTHORS   Breuza,L., Halbeisen,R., Jeno,P., Otte,S., Barlowe,C., Hong,W. and
            Hauri,H.P.
  TITLE     Proteomics of endoplasmic reticulum-Golgi intermediate compartment
            (ERGIC) membranes from brefeldin A-treated HepG2 cells identifies
            ERGIC-32, a new cycling protein that interacts with human Erv46
  JOURNAL   J Biol Chem 279 (45), 47242-47253 (2004)
   PUBMED   15308636
REFERENCE   7  (bases 1 to 1476)
  AUTHORS   Butkevich,E., Hulsmann,S., Wenzel,D., Shirao,T., Duden,R. and
            Majoul,I.
  TITLE     Drebrin is a novel connexin-43 binding partner that links gap
            junctions to the submembrane cytoskeleton
  JOURNAL   Curr Biol 14 (8), 650-658 (2004)
   PUBMED   15084279
REFERENCE   8  (bases 1 to 1476)
  AUTHORS   Townsley,F.M., Wilson,D.W. and Pelham,H.R.
  TITLE     Mutational analysis of the human KDEL receptor: distinct structural
            requirements for Golgi retention, ligand binding and retrograde
            transport
  JOURNAL   EMBO J 12 (7), 2821-2829 (1993)
   PUBMED   8392934
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC092600.1.
            
            On Apr 22, 2005 this sequence version replaced XM_341860.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC092600.1, FQ213542.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1476
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..1476
                     /gene="Kdelr1"
                     /note="KDEL endoplasmic reticulum protein retention
                     receptor 1"
                     /db_xref="GeneID:361577"
                     /db_xref="RGD:1306764"
     exon            1..180
                     /gene="Kdelr1"
                     /inference="alignment:Splign:2.1.0"
     CDS             90..728
                     /gene="Kdelr1"
                     /note="KDEL receptor 1; KDEL (Lys-Asp-Glu-Leu) endoplasmic
                     reticulum protein retention receptor 1"
                     /codon_start=1
                     /product="ER lumen protein-retaining receptor 1"
                     /protein_id="NP_001017385.1"
                     /db_xref="GeneID:361577"
                     /db_xref="RGD:1306764"
                     /translation="MNLFRFLGDLSHLLAIILLLLKIWKSRSCAGISGKSQVLFAVVF
                     TARYLDLFTNYISLYNTCMKVVYIACSFTTVWMIYSKFKATYDGNHDTFRVEFLVVPT
                     AVLAFLVNHDFTPLEILWTFSIYLESVAILPQLFMVSKTGEAETITSHYLFALGVYRT
                     LYLFNWIWRYHFEGFFDLIAIVAGLVQTVLYCDFFYLYITKVLKGKKLSLPA"
     exon            181..281
                     /gene="Kdelr1"
                     /inference="alignment:Splign:2.1.0"
     exon            282..440
                     /gene="Kdelr1"
                     /inference="alignment:Splign:2.1.0"
     exon            441..693
                     /gene="Kdelr1"
                     /inference="alignment:Splign:2.1.0"
     exon            694..1441
                     /gene="Kdelr1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccgccctca gcccagcagc accacagctc cggggcagcc cggccggcca gcctcccccc
       61 cagctcagcc ctgcccgagt cctccagtca tgaacctctt ccgattcctg ggagacctct
      121 cccacctcct agctatcatc ttgttactgc tcaaaatctg gaagtcccga tcgtgtgcgg
      181 gcatttcagg gaagagccaa gtcctgtttg ctgtggtgtt cactgcccga tatctggacc
      241 tgttcaccaa ctacatttca ctctacaata cctgcatgaa ggtggtctac atagcttgtt
      301 cctttaccac ggtgtggatg atctacagca agttcaaagc tacgtatgat gggaaccacg
      361 acactttccg ggtggagttc ctcgttgttc ctactgctgt tttggcgttc ctggttaacc
      421 atgacttcac ccctctggag atcctctgga ctttctccat ctacctggag tcagtggcta
      481 tcttgccaca gctgttcatg gtgagcaaga cgggcgaggc agagaccatc accagccatt
      541 acctgttcgc actgggtgtc taccgtacac tctatctctt caactggatc tggcgctacc
      601 acttcgaggg cttctttgac ctcatcgcca ttgttgctgg cctggtccag acagtcctct
      661 actgcgattt cttctacctc tacatcacca aagtcctaaa ggggaagaag ctgagcttgc
      721 cggcgtaacc ctggcctcac cagccttctc cgaggcaggg caggaggcag agaagagaaa
      781 ggctgtggag accaagagcc ttcccatcca gagttgactt tgtgaagagc tcacctctcc
      841 tggctccctg cccctccagc tgggttttgg gtccatggaa gacccttctc ctggggagct
      901 caggacctga gctgtttgta gccttttgcc ttttagagaa gaaaaacaaa aaacaaatct
      961 ttccactatt tagtttttga ttctgatgac ttttttctct tctacctggc cctgattttt
     1021 tataaactgt gttttgagtg ttctctggac cagggccggt ggaggtctgt ccccttctcc
     1081 aaggtcccac cccagcccca tggttgccaa acactacgtc tgccaatgtc tgcctgccca
     1141 ccttggctgt gaccacgatg ttcccttcaa gttcctggat cggtggtaag aaggaagaaa
     1201 gttaaggagg gtctcctaat ttttcatgat ttccccccca gaatttgtta gctttttgtg
     1261 tggggggagg gaagggtagg cttgtcctgt ttttgataaa taaggggacg ctatgggctt
     1321 aggcaaggga aagaggttgg ctgacccagg tggtgaccta actacactct gacaccatgt
     1381 ttttgtacag aatttgatgg ctgactcttt gttctcttga aataaaccaa ggaaaactgt
     1441 caaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
//
