LOCUS       NM_001100172            2840 bp    mRNA    linear   ROD 17-JUL-2023
DEFINITION  Rattus norvegicus potassium channel tetramerization domain
            containing 8 (Kctd8), mRNA.
ACCESSION   NM_001100172 XM_001070098 XM_344237
VERSION     NM_001100172.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2840)
  AUTHORS   Schwenk J, Metz M, Zolles G, Turecek R, Fritzius T, Bildl W,
            Tarusawa E, Kulik A, Unger A, Ivankova K, Seddik R, Tiao JY, Rajalu
            M, Trojanova J, Rohde V, Gassmann M, Schulte U, Fakler B and
            Bettler B.
  TITLE     Native GABA(B) receptors are heteromultimers with a family of
            auxiliary subunits
  JOURNAL   Nature 465 (7295), 231-235 (2010)
   PUBMED   20400944
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from EF043041.1.
            
            On or before Jul 29, 2007 this sequence version replaced
            XM_344237.3, XM_001070098.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EF043041.1, EV767897.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132272, SAMD00132285
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2840
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p11"
     gene            1..2840
                     /gene="Kctd8"
                     /note="potassium channel tetramerization domain containing
                     8"
                     /db_xref="GeneID:364148"
                     /db_xref="RGD:1312020"
     exon            1..1338
                     /gene="Kctd8"
                     /inference="alignment:Splign:2.1.0"
     CDS             369..1799
                     /gene="Kctd8"
                     /note="potassium channel tetramerisation domain containing
                     8"
                     /codon_start=1
                     /product="BTB/POZ domain-containing protein KCTD8"
                     /protein_id="NP_001093642.1"
                     /db_xref="GeneID:364148"
                     /db_xref="RGD:1312020"
                     /translation="MALKDTGSGGSTILPISEMVSASSSPGAPLAAAPGPCAPSPFPE
                     VVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGDLPRDSRARFFIDRD
                     GFLFRYVLDYLRDKQLALPEHFPEKERLLREAEFFQLTDLVKLLSPKVTKQNSLNDEG
                     CQSDLEDNLSQGSSDALLLRGAAAGAPSSSGAHGVSGVVSGGSAPDKRSGFLTLGYRG
                     SYTTVRDNQADAKFRRVARIMVCGRIALAKEVFGDTLNESRDPDRQPEKYTSRFYLKF
                     TYLEQAFDRLSEAGFHMVACNSSGTAAFVNQYRDDKIWSSYTEYIFFRPPQKIVSPKQ
                     EHEDRKCDKVTDKGSESGTSCNELSTSSCDSHSEASTPQDNLVNTQQAVSQQPNTLTL
                     DRPSRKAPVQWMPPPDKRRNSELFQSLISKSRETNLSKKKVCEKLSVEEEMKKCIQDF
                     KKIHIPDCFPERKRQWQSELLQKYGL"
     exon            1339..2840
                     /gene="Kctd8"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2181..2186
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kctd8"
     regulatory      2281..2286
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kctd8"
     regulatory      2340..2345
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Kctd8"
ORIGIN      
        1 aggcgcgctg gctcacaagc agccgggggt gagttttctt cgctcgggcc ccgcctcctg
       61 ccctcccctc ccagagccgc gcgcagcccc cgaacctctc caagtctctt gtacacttgc
      121 agtcggtcgc cccaaaggag cagccgagct cgcggagctc cattcctgag agtctctccc
      181 cgatggagct cgggcgactc cgacgccgct gctgcccgga accctgagca gcgccgggtg
      241 cctggaggac cgcgccggtc agccagagag tgccggttga ccgagcgcac gccgaggacc
      301 cgagacctcg aggctctggg aagcgcgctg tgcggctcgc ccgggtcacc tggccggtgg
      361 cggggaccat ggctttgaag gacacgggca gcggcggcag caccatcctc ccgatcagcg
      421 agatggtgtc cgcgtccagc tctccaggcg ctccgctggc cgccgcccca gggccctgcg
      481 ccccgtctcc cttcccggag gtagtagaac tgaatgttgg cggccaggtt tatgtgacca
      541 agcattcgac gttgctcagc gtcccggaca gcactctggc cagcatgttc tctccctcta
      601 gtccccgggg cggcgctcgg cgccggggcg acttgcccag ggacagccgc gcgcgcttct
      661 tcatcgaccg cgacggcttc ctctttaggt acgtgctgga ttacctgcgc gacaagcagc
      721 tggcgctgcc cgagcacttc cccgagaagg agaggctcct gcgcgaggca gagttcttcc
      781 agcttactga cctggtcaag ctgctgtcgc ccaaggtcac caagcagaac tcgctcaacg
      841 acgagggctg ccagagcgac ctggaggaca acctttccca gggcagcagc gacgcactgc
      901 tgctgcgtgg ggcggcggcc ggcgcgccct cgagttctgg ggcacacggt gtcagtggcg
      961 ttgtcagtgg cggcagcgct ccggacaagc gctctgggtt cctcacactg ggctaccgtg
     1021 gctcctacac cacagtgcga gacaaccagg cagatgccaa gtttaggcgt gtggcgcgca
     1081 tcatggtgtg cgggcgcata gccttggcca aggaggtctt tggggacact cttaatgaga
     1141 gtcgcgaccc tgaccgtcag cctgagaagt acacatcccg cttctacctc aagttcacct
     1201 acttggagca ggcattcgat cgactctctg aggctggctt ccacatggtg gcgtgcaact
     1261 cctctggcac tgccgccttt gtcaaccagt accgagacga caagatctgg agcagttata
     1321 ctgaatacat cttcttccga ccacctcaga aaatagtgtc acccaaacaa gaacatgaag
     1381 acaggaaatg tgacaaagtc acagacaaag gaagtgagag tgggacttcc tgcaatgagc
     1441 tctccacatc cagctgtgac agccactcag aggccagcac tccacaggac aacctggtca
     1501 acactcagca ggctgtatct cagcagccta acaccttaac cttggataga ccctcccgga
     1561 aagcccctgt tcagtggatg ccgccaccag acaagcgcag aaacagtgaa ctctttcagt
     1621 cactcatcag caagtcccga gagacaaatc tctccaaaaa gaaggtctgc gagaagctaa
     1681 gtgtggaaga agaaatgaaa aagtgtattc aggattttaa aaaaatccac attccagatt
     1741 gttttccaga gcgcaaacgc cagtggcaat ctgaactgct ccaaaaatat gggttgtagt
     1801 aatgatgatg ttctgggcgt gtttcgatgg cgttcaatgt ttactaccat gtcaccgcct
     1861 aactgatggc tggtgtgatt cttgctgctc ttcctttctg tgaacagtgg atgtgggaca
     1921 gtattttttt tcattacttt tattgttgtt tttagaaaga taattttaaa aatgaaacca
     1981 acaagtgtgt atcaaaatgg tttagctatc tgattcaagc cattttgtaa taatgagcgt
     2041 ataatgtgca tgatcaagaa acttagaatc ttgattttcg agctgtggtt gactggacat
     2101 gtttgtcatt ctgtaactca caaaacaaca agttatcata tcacaccgat tgagacaaga
     2161 atgtacatga aaagacatga aataaaaatt tcaacgatgg ttttaggacc caaatataca
     2221 actgtttaaa tgttaatgca ttaaaacaag tattattttt tgcatgaaca caatgttaca
     2281 aataaatctc aagaaatagg gaagaactgt ttgtggcttt gaaagaaaaa atattaaaaa
     2341 ataaagcaaa tatatatata tatgtaatat atataatagt ttcaggcaaa gcctgtaatt
     2401 gtaaactgtc taggattgaa cttttttgtt cccgatctgt ggttcttttg tgtaaatgta
     2461 aggtgtttcc gtatgttaag atggtgtaaa tatgctttat tctgttatgt tatagcatca
     2521 acattcatca atcaaaacta atcatgaata tttctgtgaa atgagtcttt ttacatcagg
     2581 ctgtgaaact cgtataatga tgatttaaaa gattccatta tcatgttaat caaaataatt
     2641 gaaggaaatg gcaaagagct ttatgtgttt attaaaaatg gaaaatgtat tagaattcct
     2701 taatttcttc tgacttttct ttaaaaaata ttttttatca tctttgatgt tcatttaaac
     2761 accatattag agaatggttg acaaattcaa atgttggaaa gattgaacat aattcaaact
     2821 gaggtagaga gccagatcgt
//
