LOCUS       NM_001107253            1420 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus potassium channel tetramerization domain
            containing 6 (Kctd6), mRNA.
ACCESSION   NM_001107253 XM_001070711 XM_223921
VERSION     NM_001107253.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1420)
  AUTHORS   Smaldone,G., Pirone,L., Pedone,E., Marlovits,T., Vitagliano,L. and
            Ciccarelli,L.
  TITLE     The BTB domains of the potassium channel tetramerization domain
            proteins prevalently assume pentameric states
  JOURNAL   FEBS Lett 590 (11), 1663-1671 (2016)
   PUBMED   27152988
REFERENCE   2  (bases 1 to 1420)
  AUTHORS   Lange,S., Perera,S., Teh,P. and Chen,J.
  TITLE     Obscurin and KCTD6 regulate cullin-dependent small ankyrin-1
            (sAnk1.5) protein turnover
  JOURNAL   Mol Biol Cell 23 (13), 2490-2504 (2012)
   PUBMED   22573887
REFERENCE   3  (bases 1 to 1420)
  AUTHORS   De Smaele,E., Di Marcotullio,L., Moretti,M., Pelloni,M.,
            Occhione,M.A., Infante,P., Cucchi,D., Greco,A., Pietrosanti,L.,
            Todorovic,J., Coni,S., Canettieri,G., Ferretti,E., Bei,R.,
            Maroder,M., Screpanti,I. and Gulino,A.
  TITLE     Identification and characterization of KCASH2 and KCASH3, 2 novel
            Cullin3 adaptors suppressing histone deacetylase and Hedgehog
            activity in medulloblastoma
  JOURNAL   Neoplasia 13 (4), 374-385 (2011)
   PUBMED   21472142
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474010.1.
            
            [WARNING] On Jul 16, 2024 this sequence was replaced by
            NM_001107253.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001070711.1, XM_223921.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC158799.1, CO397427.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760494, SAMN06680441
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1420
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p14"
     gene            1..1420
                     /gene="Kctd6"
                     /note="potassium channel tetramerization domain containing
                     6"
                     /db_xref="GeneID:305792"
                     /db_xref="RGD:1308208"
     exon            1..72
                     /gene="Kctd6"
                     /inference="alignment:Splign:2.1.0"
     CDS             46..759
                     /gene="Kctd6"
                     /note="potassium channel tetramerisation domain containing
                     6"
                     /codon_start=1
                     /product="BTB/POZ domain-containing protein KCTD6"
                     /protein_id="NP_001100723.1"
                     /db_xref="GeneID:305792"
                     /db_xref="RGD:1308208"
                     /translation="MDNGDWSYMMTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGG
                     DFPTARDPQGNYFIDRDGPLFRYVLNFLRTSELTLPLDFKEFDLLRKEADFYQIEPLI
                     QCLNDPKPLYPMDTFEEVVELSSTRKLSKYSNPVAVIITQLTITTKVHSLLEGISNYF
                     TKWNKHMMDTRDCQVSFTFGPCDYHQEVSLRVHLMEYITKQGFTIRNTRVHHMSERAN
                     ENTVEHNWTFCRLARKTDD"
     exon            73..1420
                     /gene="Kctd6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtttccctg gcttctgagc tcctggagac gcagtgctgg agcagatgga taatggagac
       61 tggagctata tgatgactga cccagtcacg ttaaatgtag gcggacactt gtacacgaca
      121 tctcttacca cgttgacacg ctacccggat tctatgcttg gagctatgtt tggaggtgac
      181 ttccccacag ccagagaccc tcaaggcaat tacttcatcg atcgagacgg accgcttttc
      241 cgttacgtcc tcaacttctt acggacttca gaattgacgc tccccctgga cttcaaggag
      301 tttgatctgc ttcggaaaga ggccgacttc taccagatcg agcccctgat tcagtgtctc
      361 aatgacccta agcctttgta tcctatggat acttttgaag aagttgtaga gctgtccagt
      421 actcggaagc tttctaaata ctccaatccc gtggctgtca tcataaccca gttgaccatc
      481 accaccaagg tccattccct actggaaggc atctcaaact attttaccaa gtggaataaa
      541 cacatgatgg ataccagaga ctgtcaggtc tctttcacct ttggaccgtg cgattaccac
      601 caggaagtct cccttcgggt ccacctgatg gagtacatta cgaagcaagg cttcacgatc
      661 cgcaatactc gggtgcatca catgagcgag cgggccaatg agaacacagt agagcacaac
      721 tggactttct gtagactggc ccgcaagacg gacgactgac tggcggccag ccctcagaga
      781 atttcctgca agctcacgtt tcgggacatg gaagagactt gttgtttagt gtgggccctc
      841 ctttttcctt tttttttttt cccctccagt ctttgtattt atttgaaggc actgaggacc
      901 agaaggaagt tttgtgtgtg agcggtcccc tccctgtttt gttcccaagt atgcatgtgc
      961 ctgttccgag tctctagaaa ccttttttat aaaaagagat ctgaaaatca ttatggtata
     1021 taatccaccc ttaacagtgc taaaatgatt tatgataacg tggtccgtga ctcgacagga
     1081 aggctaaaaa tacaggaata caagattaaa gagggtgttg ctctgactag tttccagacc
     1141 agtaggccgt attgcagtat taaaggaaga ctggccagcc atctaaaggt actcgttaag
     1201 gactgctctc tacagttttg acaactgttt ctttctatgc acataaatca agcaaccaaa
     1261 tatctgtagc catggaaatg tctgactaga aatatttata ttggagtctc agtacaaatg
     1321 tccctgtggt agaaacctta tgcctgctac agtttcattc ccaagggtac tgcctaccag
     1381 gaaagaaaat ctaataaaaa aaaatggaat atgaacatta
//
