LOCUS       NM_001395732            1740 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus potassium channel tetramerization domain
            containing 17 (Kctd17), transcript variant 1, mRNA.
ACCESSION   NM_001395732 XM_008765710
VERSION     NM_001395732.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1740)
  AUTHORS   Mencacci,N.E., Rubio-Agusti,I., Zdebik,A., Asmus,F., Ludtmann,M.H.,
            Ryten,M., Plagnol,V., Hauser,A.K., Bandres-Ciga,S., Bettencourt,C.,
            Forabosco,P., Hughes,D., Soutar,M.M., Peall,K., Morris,H.R.,
            Trabzuni,D., Tekman,M., Stanescu,H.C., Kleta,R., Carecchio,M.,
            Zorzi,G., Nardocci,N., Garavaglia,B., Lohmann,E., Weissbach,A.,
            Klein,C., Hardy,J., Pittman,A.M., Foltynie,T., Abramov,A.Y.,
            Gasser,T., Bhatia,K.P. and Wood,N.W.
  TITLE     A missense mutation in KCTD17 causes autosomal dominant
            myoclonus-dystonia
  JOURNAL   Am J Hum Genet 96 (6), 938-947 (2015)
   PUBMED   25983243
REFERENCE   2  (bases 1 to 1740)
  AUTHORS   Kasahara,K., Kawakami,Y., Kiyono,T., Yonemura,S., Kawamura,Y.,
            Era,S., Matsuzaki,F., Goshima,N. and Inagaki,M.
  TITLE     Ubiquitin-proteasome system controls ciliogenesis at the initial
            step of axoneme extension
  JOURNAL   Nat Commun 5, 5081 (2014)
   PUBMED   25270598
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Aug 3, 2021 this sequence version replaced XM_008765710.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.40785.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-258               JAXUCZ010000007.1  111859556-111859813
            259-367             JAXUCZ010000007.1  111860910-111861018
            368-459             JAXUCZ010000007.1  111864088-111864179
            460-555             JAXUCZ010000007.1  111865010-111865105
            556-681             JAXUCZ010000007.1  111866638-111866763
            682-775             JAXUCZ010000007.1  111867942-111868035
            776-850             JAXUCZ010000007.1  111868199-111868273
            851-938             JAXUCZ010000007.1  111868625-111868712
            939-1740            JAXUCZ010000007.1  111869528-111870329
FEATURES             Location/Qualifiers
     source          1..1740
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..1740
                     /gene="Kctd17"
                     /gene_synonym="RGD1311154"
                     /note="potassium channel tetramerization domain containing
                     17"
                     /db_xref="GeneID:300317"
                     /db_xref="RGD:1311154"
     exon            1..258
                     /gene="Kctd17"
                     /gene_synonym="RGD1311154"
                     /inference="alignment:Splign:2.1.0"
     CDS             49..1008
                     /gene="Kctd17"
                     /gene_synonym="RGD1311154"
                     /note="isoform 1 is encoded by transcript variant 1;
                     BTB/POZ domain-containing protein KCTD17; potassium
                     channel tetramerisation domain containing 17"
                     /codon_start=1
                     /product="BTB/POZ domain-containing protein KCTD17 isoform
                     1"
                     /protein_id="NP_001382661.1"
                     /db_xref="GeneID:300317"
                     /db_xref="RGD:1311154"
                     /translation="MQTPRPAMRMEAGEAAPPVGAGGRSGGGWGKWVRLNVGGTVFLT
                     TRQTLCREQKSFLSRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFLRHGKLVLDKD
                     MAEEGVLEEAEFYNIGPLIRIIKDRMEEKDYTVTQVPPKHVYRVLQCQEEELTQMVST
                     MSDGWRFEQLVNIGSSYNYGSEDQAEFLCVVSKELHSSPHGLSSESTRKTKSTDEQLE
                     EQRRQEVEEVEVAQVQVEADAQEKALSSQDPANLFSLPPPPPPPPLPAGGPCPHPPRP
                     KPELAVRAPRPRARPQSCRPCYYKPEAPGCEPPDHLQGLGVPI"
     exon            259..367
                     /gene="Kctd17"
                     /gene_synonym="RGD1311154"
                     /inference="alignment:Splign:2.1.0"
     exon            368..459
                     /gene="Kctd17"
                     /gene_synonym="RGD1311154"
                     /inference="alignment:Splign:2.1.0"
     exon            460..555
                     /gene="Kctd17"
                     /gene_synonym="RGD1311154"
                     /inference="alignment:Splign:2.1.0"
     exon            556..681
                     /gene="Kctd17"
                     /gene_synonym="RGD1311154"
                     /inference="alignment:Splign:2.1.0"
     exon            682..775
                     /gene="Kctd17"
                     /gene_synonym="RGD1311154"
                     /inference="alignment:Splign:2.1.0"
     exon            776..850
                     /gene="Kctd17"
                     /gene_synonym="RGD1311154"
                     /inference="alignment:Splign:2.1.0"
     exon            851..938
                     /gene="Kctd17"
                     /gene_synonym="RGD1311154"
                     /inference="alignment:Splign:2.1.0"
     exon            939..1740
                     /gene="Kctd17"
                     /gene_synonym="RGD1311154"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccggcatgcc ccacacctgg tacccgcccg ctgcgtgcgg agggaaggat gcagacaccg
       61 cggccggcga tgaggatgga ggccggggag gcagcgccac cggtgggggc gggcggccgc
      121 tctgggggcg gctggggcaa gtgggtgcgg ctgaatgtgg ggggcacggt gttcctgacc
      181 acccgccaga cgctgtgccg ggagcagaag tccttcctca gccgcctgtg ccaaggcgaa
      241 gagctgcaat cggacaggga tgagaccggg gcctacctca ttgaccgtga ccccacctac
      301 ttcgggccca tattgaactt cctcaggcat ggcaaattgg tgctggacaa ggacatggct
      361 gaggaggggg tcctggagga agctgagttc tacaacatcg gtcctctgat tcgaatcatc
      421 aaagacagga tggaggaaaa agactacaca gtgacccagg tgccacccaa gcacgtgtac
      481 cgagtgctgc agtgccagga ggaggaactc acacagatgg tctccactat gtccgatggc
      541 tggcgcttcg agcagctggt gaacatcggt tcctcctaca actatgggag tgaggaccag
      601 gccgagttcc tgtgtgtggt gtctaaggaa ctccacagct ccccccacgg cctgagttcg
      661 gagtccactc gcaagaccaa gagcacggac gagcagctgg aggagcagcg gcggcaggag
      721 gtggaggagg tggaggtggc ccaggtgcag gtggaggcgg atgcccagga gaaagccctg
      781 tcatctcagg atcccgctaa ccttttctcc ctcccaccac cgcctcctcc tcctccgctt
      841 cctgctggag gtccctgtcc gcaccctccc agacccaagc ctgagcttgc tgtgagagct
      901 cctcggcccc gcgcccgccc ccagagctgc cgcccctgct attacaagcc agaggcaccc
      961 ggatgtgagc ccccagatca cctccaggga cttggggttc cgatctgaaa tcctttattt
     1021 ttgtaccacg gggtgggccc ctggcccgag gaggaagact tgtcctccgc cttgtcaatg
     1081 ctgcctgcat ctgccgggct gagactcact cctgcctcgg ggcccgggcc tggggccctc
     1141 tgggaccttg gaaggcctga ggtgggccct ggggtctcca ggcagagtca ccatggccaa
     1201 actgtggcac tgcccaccca tatctcccag gcccttctgt cccctcacct gggccccctt
     1261 gctgcatggc ggatacactc cctcccagct cagtcatagc acctcctaga gcctcagtct
     1321 ccatggcacc acagggtcac ctcctcctcc cacctacctc acagggttgt tgtgagaatc
     1381 agagaggacc atggggttcc tggaagccct aagtgtgctg gggctgcaat cattacctgc
     1441 tgaggggagg tactctctag cccagcccct gtatgggaca ctatggcctc agatactggt
     1501 gggggacaat gtgaggactt agccaggcag gaaggaaagt acagacttga cagcaccttg
     1561 gccacccctc ccctctgcca ctgtgtgttt gccagcagag tatggtgtcc aggaacttgg
     1621 gatggggaag gggacaggtg taaagggctg agctgcccca cccgggatgg ggacatgtct
     1681 atcagttgtg tcctgcccac catgaaataa acctgaatga acaggcttga cctggctgcc
//
