LOCUS       NM_001109141            2418 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus potassium channel tetramerization domain
            containing 15 (Kctd15), mRNA.
ACCESSION   NM_001109141 XM_001077040 XM_001077060 XM_001077071 XM_574422
VERSION     NM_001109141.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2418)
  AUTHORS   Smaldone,G., Pirone,L., Pedone,E., Marlovits,T., Vitagliano,L. and
            Ciccarelli,L.
  TITLE     The BTB domains of the potassium channel tetramerization domain
            proteins prevalently assume pentameric states
  JOURNAL   FEBS Lett 590 (11), 1663-1671 (2016)
   PUBMED   27152988
REFERENCE   2  (bases 1 to 2418)
  AUTHORS   Gutierrez-Aguilar,R., Kim,D.H., Woods,S.C. and Seeley,R.J.
  TITLE     Expression of new loci associated with obesity in diet-induced
            obese rats: from genetics to physiology
  JOURNAL   Obesity (Silver Spring) 20 (2), 306-312 (2012)
   PUBMED   21779089
  REMARK    GeneRIF: Long-Evans rats maintained on chow or a high-fat diet
            (HFD) for 6 weeks. From a total of 19 genes analyzed, seven genes
            (ETV5, FTO, GNPDA2, KCTD15, TMEM18, MC4R, and SH2B1) were
            down-regulated in the hypothalamus of HFD compared to chow-fed rats
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473979.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_574422.2, XM_001077040.1, XM_001077060.1, XM_001077071.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2418
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..2418
                     /gene="Kctd15"
                     /note="potassium channel tetramerization domain containing
                     15"
                     /db_xref="GeneID:499129"
                     /db_xref="RGD:1583737"
     exon            1..261
                     /gene="Kctd15"
                     /inference="alignment:Splign:2.1.0"
     exon            262..354
                     /gene="Kctd15"
                     /inference="alignment:Splign:2.1.0"
     CDS             289..1140
                     /gene="Kctd15"
                     /note="potassium channel tetramerisation domain containing
                     15"
                     /codon_start=1
                     /product="BTB/POZ domain-containing protein KCTD15"
                     /protein_id="NP_001102611.1"
                     /db_xref="GeneID:499129"
                     /db_xref="RGD:1583737"
                     /translation="MPHRKERPSGSSLNAHGSSGTAEGGNMSRLSLTRSPVSPLAAQG
                     IPLPAQLTKANAPVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYF
                     IDRDGEIFRYILSFLRTSKLLLPDDFKDFNLLYEEARYYQLQPMVRELERWQQEQEQR
                     RRSRACDCLVVRVTPDLGERIALSGEKALIEEVFPETGDVMCNSVNAGWNQDPTHVIR
                     FPLNGYCRLNSVQVLERLFQRGFSVAASCGGGVDSSQFSEYVLCREERRPQPTPTAVR
                     IKQEPLD"
     exon            355..530
                     /gene="Kctd15"
                     /inference="alignment:Splign:2.1.0"
     exon            531..675
                     /gene="Kctd15"
                     /inference="alignment:Splign:2.1.0"
     exon            676..981
                     /gene="Kctd15"
                     /inference="alignment:Splign:2.1.0"
     exon            982..2418
                     /gene="Kctd15"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acagcttgga gaagcgggtc aatgctgggc cagtttacaa acccgccgag gtatctgcaa
       61 caggctgctt ggccaaacct cagccgcgcc tgggtcctgg tgtctggtgc agtgaactcg
      121 tgtgtctctt atcaagtgca ctttctatgt ttgtgatctc agcagtgttc tgggaagaag
      181 ggtcgtggtc caccacagat gcgtttgtca gagggagcag tggagattcg ggtcaaggct
      241 taaggcctgg ggcttccaat gatactctgg gcagggatgg aagcctaaat gcctcaccgc
      301 aaggagcggc cgagcgggtc ctcgcttaac gcacacggca gcagcggcac cgcggaggga
      361 ggaaatatgt cccggctgtc actcacccgg tcgcctgtgt ctcccctggc tgcccagggg
      421 atcccactgc cagctcagct caccaaagcc aacgcacctg tgcacatcga cgtgggaggt
      481 cacatgtata ccagcagcct ggccacactc accaagtacc ctgactccag aataagccgt
      541 ctcttcaacg gcacggagcc cattgtccta gacagtctca agcaacatta tttcatcgac
      601 cgggatgggg agattttccg ctacatcctg agtttcctgc ggacgtccaa actgctgctt
      661 ccagatgact tcaaggactt caacctactg tatgaggaag cgaggtacta ccagctgcag
      721 cccatggtgc gtgagctgga gcgctggcag caagagcaag aacagcgacg tcgtagccgg
      781 gcctgtgact gcctggtggt gcgggtcacc cctgacctgg gcgaacggat cgcactcagt
      841 ggagagaagg ccctcattga ggaggtcttc ccggagaccg gagatgtcat gtgcaactct
      901 gtcaacgccg gctggaacca ggaccccacg cacgtcatcc gtttccctct caacggctac
      961 tgtcgactca actcggtgca ggtcttggaa aggctgtttc agagagggtt cagcgtggcc
     1021 gcctcctgtg ggggtggtgt ggactcttcc cagttcagcg agtacgtact ttgccgggaa
     1081 gagcggcgac cgcagcccac cccaactgct gtccggataa agcaggagcc cctggactag
     1141 gcaggcgctg cctcggtgcc cacctaagac ccctcggtcc tggggcaacc ccaaggacat
     1201 ggaaatagtg ctgaggagcc ctgcctgttt gcgctgcaca gtaggcccaa gactgagggc
     1261 gggaacggag ggtctgagct cacccccggg aatgccaggt gcggaggtaa ccggtcgagg
     1321 cgtgccggag gcatgcccac ggaaggactg ttaatgtgac cgggagatgc cgcggctgct
     1381 gcaacggtgc cgccagcttc ccagccctcc cactcctcag catcctctgg tacagcatcc
     1441 tctgctggcc cagtcactcc agagcagctg tttatcctcc acacttggca gacatatttt
     1501 tctacagtat ttaaaacagg actaactgtc actgcacagg tcggcaaggc taacgaggac
     1561 cattgctgct tttacctggt gctcagttct cagtccaact gttcagcaag caaaggatgg
     1621 gatgccggca ttcgggccca ggtgcctgct ggggctgtgg ggacagatgt ggggtggcgg
     1681 tgctacagga ggtggaacag ggtcctggag gggcagggca gccgggaaga gggcaatggg
     1741 gggtgggggc tgtgtgactc tgtgactttt atctgagaca ctctgctgcc acctgtgtcc
     1801 cagaatgcgc ttggtgcaca cctgacctgc taacgcccag gggcttccaa tcccaactga
     1861 ctgtgctcac atctgggttc ttggagaagt ctccacccac ccagtcagca tgggaatcac
     1921 agcttatctc aggaatgggt ctttctacca agggtcccat ctgtcagcat cactctctgg
     1981 gtccccagct cagggaacca ccctccaccc tagctccagt tttcccattc atatgcacat
     2041 caagtgttaa ttaaatgtcc taaaactagc ctgtctgtaa ggcccagacc cagacttacc
     2101 tagtgctctt aaccccagat ttccaacaag gactggtcct gagaggtcct cacagatctg
     2161 ccctctccca gaggacaggc ccaaaagatg gataccctgg ccttgtcaca tctcccctag
     2221 ctcctcccaa gtggaggaac cgcagagaac tgacagatgg ggtgccctgg ccggcacccc
     2281 cttgtgtaca gcgcctgtag aacttgtata tgactccttt aatattgtaa agacgctgat
     2341 gtacaattgt tccgtgtttg tgtgaacaca ccgcgttccc ggttcatgcc ataaaggacg
     2401 ctataaagca aaagactg
//
