LOCUS       NM_001009973            2913 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus potassium channel tetramerization domain
            containing 10 (Kctd10), mRNA.
ACCESSION   NM_001009973
VERSION     NM_001009973.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2913)
  AUTHORS   Ren,K., Yuan,J., Yang,M., Gao,X., Ding,X., Zhou,J., Hu,X., Cao,J.,
            Deng,X., Xiang,S. and Zhang,J.
  TITLE     KCTD10 is involved in the cardiovascular system and Notch signaling
            during early embryonic development
  JOURNAL   PLoS One 9 (11), e112275 (2014)
   PUBMED   25401743
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2913)
  AUTHORS   Chih,B., Liu,P., Chinn,Y., Chalouni,C., Komuves,L.G., Hass,P.E.,
            Sandoval,W. and Peterson,A.S.
  TITLE     A ciliopathy complex at the transition zone protects the cilia as a
            privileged membrane domain
  JOURNAL   Nat Cell Biol 14 (1), 61-72 (2011)
   PUBMED   22179047
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2913)
  AUTHORS   Zhou,J., Ren,K., Liu,X., Xiong,X., Hu,X. and Zhang,J.
  TITLE     A novel PDIP1-related protein, KCTD10, that interacts with
            proliferating cell nuclear antigen and DNA polymerase delta
  JOURNAL   Biochim Biophys Acta 1729 (3), 200-203 (2005)
   PUBMED   15982757
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY318756.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY318756.2, FQ131040.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2913
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="W"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q16"
     gene            1..2913
                     /gene="Kctd10"
                     /note="potassium channel tetramerization domain containing
                     10"
                     /db_xref="GeneID:494521"
                     /db_xref="RGD:1591979"
     exon            1..30
                     /gene="Kctd10"
                     /inference="alignment:Splign:2.1.0"
     CDS             28..975
                     /gene="Kctd10"
                     /note="BTB/POZ domain-containing protein KCTD10"
                     /codon_start=1
                     /product="BTB/POZ domain-containing adapter for
                     CUL3-mediated RhoA degradation protein 3"
                     /protein_id="NP_001009973.1"
                     /db_xref="GeneID:494521"
                     /db_xref="RGD:1591979"
                     /translation="MEEMSGESVVTSAVPAAATRTTSFKGASPSSKYVKLNVGGALYY
                     TTMQTLTKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESR
                     REIEELLAEAKYYLVQGLLEECQAALQNKDTYEPFCKVPVITSSKEEQRLIATSDKPA
                     VKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYG
                     QGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYEAQDGRGPDNALLEATG
                     GAAGRSHHLDEDEERERERIERVRRIHIKRPDDRAHLHQ"
     exon            31..244
                     /gene="Kctd10"
                     /inference="alignment:Splign:2.1.0"
     exon            245..414
                     /gene="Kctd10"
                     /inference="alignment:Splign:2.1.0"
     exon            415..501
                     /gene="Kctd10"
                     /inference="alignment:Splign:2.1.0"
     exon            502..554
                     /gene="Kctd10"
                     /inference="alignment:Splign:2.1.0"
     exon            555..750
                     /gene="Kctd10"
                     /inference="alignment:Splign:2.1.0"
     exon            751..2895
                     /gene="Kctd10"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggagactccg gcgtcctccg acttttcatg gaagagatgt caggagaaag cgtggtgacc
       61 tcagcggtgc cagcggctgc tacccgcacc acttccttca agggcgccag ccccagctcc
      121 aagtacgtga agctaaacgt ggggggggcc ctctactaca ccaccatgca gacgctcacc
      181 aagcaggaca ccatgctgaa ggccatgttc agcgggcgca tggaagtgct caccgacagt
      241 gaaggctgga tcctcatcga ccgctgcggg aagcacttcg ggacaatcct caactacctt
      301 cgagacggcg ctgtgccctt gcccgagagc cgccgggaga tcgaggagct gctggcggag
      361 gccaagtact acctggtgca gggcctgctc gaagagtgcc aggcggccct acaaaataaa
      421 gacacttacg agcccttctg caaggtgcct gtcatcacat cctccaagga agagcagagg
      481 ctcatagcga cgtcagataa gccagccgtg aagctgctct acaatagaag taacaacaag
      541 tactcctaca ccagcaattc cgacgacaat atgttgaaaa acattgaact gtttgataag
      601 ctctccctgc gcttcaacgg gcgggtcctg ttcataaagg acgtcatcgg ggatgaaatc
      661 tgctgttggt cattttacgg ccagggccga aaaatcgctg aggtctgttg tacctccatt
      721 gtctacgcca ccgagaagaa gcagaccaag gttgaattcc ctgaagcccg catttatgag
      781 gagaccctga atatcttgct gtatgaggcc caggatggcc gaggacctga caatgccctc
      841 ctggaggcca cgggtggggc agctggacgc tcacatcacc tggatgagga cgaggagcgg
      901 gaacgggagc ggatcgagcg agtgcggagg atccacatca agcgcccaga cgaccgggcc
      961 cacctccacc agtgagccgg ggcaagcctg ccttctaccc tccctctgcc cctgccccct
     1021 cagacccttt gcaggctttg gggcacctcc cacttcccct ggagtctgag acacttttgt
     1081 aacaagtcag atgattattt tgttatttct tgacaaagca gattgcttct gtgttgaccc
     1141 aggtgtgcac cccttctgaa caagctgtgt ctaagggccc cacttccgaa cctggagcct
     1201 ggctttctgg gctcttggag gaaaagtatg agtgagtctg gcgtgtgtgt gagaaccttt
     1261 gttgcatatt tatttttatg gtgttgacta ttagggctcc ttcggcgact taaggactta
     1321 gtgtggcagt tttgagggac tgtggggttg gcagccagtc accaaggtgt ctgtgagcag
     1381 cctggcccgt tgctttcctg ggggtcagct ctgtatgcgg ctttgtgact ggtgcccctt
     1441 ggtcagcagt ggaaggggga ctgagtgtgc ccaagcctgt ccagggtccc tcagtgcagc
     1501 gggcgcgctg ccggccaggg agcagaccag ttcctggcag ggggctgctc tctcggctgg
     1561 ggtccttgtg tggcaccagg tcaggacact acggagtttg cagtgactcg tgtggtttcc
     1621 cctcagctcc cgtcaggtgg tttctgtgca gaatagagta ggtgtgcaga tacctttggg
     1681 tcttgtttgt gttcagggaa tgtgtatgac tgttggggac gtgtgactga ctgtagggcg
     1741 caggcgctca ggaggacgac tgcccgttag ctccagtctg ctctgcgcag aggagcctcg
     1801 gatgaagggc ggttgagtag acgagtctat ggttaggtga gtggtgggat ggattgctgc
     1861 ttgataggga aagtgttgct gtttttgacc aaaggtattg attgaggggg tgatctgaca
     1921 tgttttaaaa cgtttctatt ttgcgacgac ggtttgaaca gctcgctttg tatgtgacag
     1981 ttgtatgcct ttaaagcttt ttcttgtatc tgacagcaaa gcctacgtat gataaatgtt
     2041 cacacagtcc cgactggatc gaggaaccac atatggggta catgcttttt aacggtgtgg
     2101 ggtgaacttt tgtataaagc gccgagaaag ggagattaca gaccatgttt cctacatttt
     2161 tatactgttt gtcttcaacg tcagctaaac tgaatgtcag tcctggtgtc ttctgtagga
     2221 atggaaaagc catgatccac cctttaagtt catgtgcaga acagccgagc agcacaatct
     2281 gacttgcctg ggcctctggc cttaggttac tggtttggca gctctctcta ccttcctcta
     2341 gcctcaaacc ttgtgcctgt agctttgtgc ctccactccc aggggtagga acagacctag
     2401 cgaacattcc atggtgcctg aaaccactgg tggctgtgtc cagccaggcc caaccagcgc
     2461 ccatctccaa agctctgcct caggtcccac cgctggcgtg aagggcggta gtcagcgttt
     2521 ccaggtcacc atctagtgag tcgctgtgag aagagtgaac tttgcatgct aagggctcac
     2581 aattcactgt cgggtggcgg gctgcacccc agcaggtctg acacagcttc ctgttcctgc
     2641 tgtggaagat gggctgtttg acctctctgg aggctcagat cccactcaag ggccacgtcc
     2701 catacctgct tctcagtgtt ggtgttcagc cctccccaga gtgcgtgcag gccagagggc
     2761 tccattcagt ccctggtcac agaatcacat cactaccttc ctgcctctgc actataaaac
     2821 catgctggga gttttagaag tgctcactct tgtacaagcg tctgcggaca catgtaaaat
     2881 aaacgttaaa ctctgaaaaa aaaaaaaaaa aaa
//
