LOCUS       NM_001106370            5201 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus potassium voltage-gated channel modifier
            subfamily V member 2 (Kcnv2), mRNA.
ACCESSION   NM_001106370 XM_001079202 XM_220024
VERSION     NM_001106370.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5201)
  AUTHORS   Holter,P., Kunst,S., Wolloscheck,T., Kelleher,D.K., Sticht,C.,
            Wolfrum,U. and Spessert,R.
  TITLE     The retinal clock drives the expression of Kcnv2, a channel
            essential for visual function and cone survival
  JOURNAL   Invest Ophthalmol Vis Sci 53 (11), 6947-6954 (2012)
   PUBMED   22969075
  REMARK    GeneRIF: The present data provide evidence that the transcriptional
            regulation of Kcnv2 and Kv2.1 is a way through which the retinal
            clock system drives the functional adaptation of visual function to
            the marked daily changes in environmental lighting conditions.
            Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473953.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_220024.2, XM_001079202.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CK229772.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..5201
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q52"
     gene            1..5201
                     /gene="Kcnv2"
                     /note="potassium voltage-gated channel modifier subfamily
                     V member 2"
                     /db_xref="GeneID:294065"
                     /db_xref="RGD:1309271"
     exon            1..1514
                     /gene="Kcnv2"
                     /inference="alignment:Splign:2.1.0"
     CDS             111..1796
                     /gene="Kcnv2"
                     /note="potassium channel, subfamily V, member 2; potassium
                     channel, voltage-gated modifier subfamily V, member 2"
                     /codon_start=1
                     /product="potassium voltage-gated channel subfamily V
                     member 2"
                     /protein_id="NP_001099840.1"
                     /db_xref="GeneID:294065"
                     /db_xref="RGD:1309271"
                     /translation="MLKQSTERRWSLSYKLWNTSETEDVPNTGSNQHRKSICSMGART
                     GSQASIAPQWTEGNYNYYIEEDEDCGEEEDWKDDLAEENQKPEGPPAPLDGHTDTPTQ
                     LSTLKVNVGGHSYQLECCELANYPKTRLGRLVTSTSRNCQLGLCDDYEAKTDEYFFDR
                     DPAVFQLIYNFYTSGVLLVRDELCPRSFLEELGYWGVRLKYTPRCCRICFEERRDELS
                     EQLKIQRELRAQAQAEEAEELFRDMRFYGPQRQRLWNLMEKPFSSVAAKAMGVASNLF
                     VLISVVALALNTVEEMQHQAEQGTGGGDPRPILEHVEMLCVAFFTLEFLLRLASTPNL
                     RRFARSALNLVDLVAILPFYLQLLLECFTSEDQRHGKGSPREHDLETVGRVGKVGQVL
                     RIMRLMRIFRILKLARHSTGLRAFGFTLRQCYQQVGCLMLFITMGIFSFSAAVYSVEH
                     DVPGTNFTSILHAWWWAAVSISTVGYGDMYPETHLGRLFAFLCIAFGIILNGMPISIL
                     YNKFSDYYSKLKAYEYTAIRRERGKVNFMQRATKKMAECLSGSNAQSATRQEN"
     exon            1515..5201
                     /gene="Kcnv2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agaaagagca gctttgagag taatgcctgg ggccccagtc tgctggtctc tctaaaacag
       61 tacagggcag tgaacgctag agacaggcaa ggggtctgac tccgaacgcc atgctgaaac
      121 agagcaccga gaggagatgg tccttgagct acaagctctg gaatacctca gagactgagg
      181 atgtgcccaa cactggaagc aaccaacacc gtaagagcat ctgctccatg ggagcccgca
      241 ctggctctca ggccagcatc gcaccacagt ggaccgaggg caactacaat tactacatcg
      301 aggaagatga ggactgcggg gaggaggagg attggaagga tgatcttgct gaagagaacc
      361 agaagcccga gggcccccca gctccactgg atggccacac tgacactcca acccagctgt
      421 ctacgctaaa agtaaacgta ggcggccaca gctatcagct ggaatgctgt gagctggcca
      481 actaccccaa aacgcgcctg ggtcgcctgg tcacctccac cagccgcaac tgccagctgg
      541 gcctgtgcga tgactacgag gcaaagactg acgagtactt ctttgaccgt gacccggcgg
      601 tcttccagct catctacaac ttctacacat caggggtgtt gctggtgcga gacgagctgt
      661 gtccacgaag cttcctggag gagctgggct actggggcgt gaggctcaag tacacgccac
      721 gctgctgtcg catctgcttc gaggagcgga gggacgaact gagcgagcaa ctgaagatcc
      781 aaagggagct gcgtgcgcag gcgcaggccg aggaggccga ggaactcttt cgggacatgc
      841 gcttctatgg accacagcgt cagcgcctct ggaaccttat ggagaagccc ttctcttccg
      901 tagccgccaa ggccatgggg gtggcctcca atctcttcgt cctcatctcc gtagtggccc
      961 tggcgctcaa cacggtggag gagatgcagc accaggcgga gcagggcaca ggtggtgggg
     1021 accccaggcc catattggag cacgtggaga tgctgtgcgt ggctttcttc actctggagt
     1081 tcctgctgcg cctcgcctcc acccccaacc tgcggcgctt tgcacgcagc gccctcaacc
     1141 tggtggacct ggtggccatt ctgcctttct acctgcagct gctgctggag tgcttcacga
     1201 gcgaggacca gaggcatggc aagggctccc cacgggaaca cgacctggag accgtgggcc
     1261 gtgtgggcaa ggtgggccag gtcctgcgca tcatgcgcct catgcgcatc ttccgcatcc
     1321 tcaagctagc ccgccactcc acaggtttgc gggccttcgg cttcacgctg cgccagtgct
     1381 accagcaggt tggctgcctg atgctcttca tcactatggg catcttttcc ttctctgcag
     1441 cggtctactc ggtggagcac gacgtgcctg gtaccaactt caccagcatc ctccatgcct
     1501 ggtggtgggc tgcggtaagc atctctaccg tgggctatgg agacatgtat ccagagaccc
     1561 acctgggcag gctttttgcc ttcctctgca tcgcttttgg gattattctc aacgggatgc
     1621 ccatttccat cctctacaac aagttctccg attactacag caagctcaaa gcttacgagt
     1681 acaccgccat ccgtagggaa cggggaaaag tgaactttat gcagagagcc acgaagaaaa
     1741 tggctgaatg tttatctgga agtaatgcac agtccgccac aaggcaagag aattaaggct
     1801 tcattaggac acaaggctta tagaacccat gaatttcaaa gcttcgttgc ttcttttaaa
     1861 attatgcccc cccccgcccc tggcaacaga ggggcgtgtg aagcccacgc agacaaagag
     1921 cattcagttc aaagttctaa ctctaaaaat gctcatttgg gcccaaattc aaaactcctc
     1981 acatggccct ttagctagat tgtgtttatg tatgacgtca gtcctggaaa cggctgcaag
     2041 gaagcaacat cttagatttc tcttttagtt tctcatggca tcaagcttga tgcatatatt
     2101 tagacatgaa ttgactagag atgatttttc ctagttcaaa gcaggaggag gggcccttaa
     2161 ttttccagag aatggagcgt ctcagcagga gcaggagaaa ctttggaatc agaccaacct
     2221 ctcagccaga atcccagatc taccagctgg atggtttgta aggaacctac ttcaaccctc
     2281 tgagccttgg tctcttcaac tgtgagatgt agaatgagtt ttgatgattt gaaggatgag
     2341 ttttgggttt gaagataagt gctgtgtaca tgatagctgt tcaaagtgtc tgagtgagta
     2401 acatctgata tatcattctc agtggtttac aaccagaggc aagtcttctc cccaggccac
     2461 atttggagat gtttttgatc atcactatag ttaaaaagga tgaggcgggt tcctagcatc
     2521 tagtagatta gggaggcatg gggtgctaca gatccctaca gtatacaata gtgtctgccc
     2581 tacaaattac tagatgtcag taatgccaat gttgaggaat gtctagaatt actatgggaa
     2641 cccaaacttg gtccatgaca tttttctgta tgtatgaatt tctctctccc ttgaaaggag
     2701 cccccaagtg acctctctct taatgcagac ttccgttctt tctgtttccc agagaagggg
     2761 tgggagagca gtgctgcctc cccaacaatg gctgtaaggc aagcgctgga agacctctct
     2821 aggctgaggg ttggaaacca gtgccctttg ggtcatttct cttcttgaga tctttctttt
     2881 aattcctttc tgagtccaca gggctcctgt aaattgaagt cttaaaatca aaggctcatt
     2941 tgaacagagc acacagagat ttgcccccta gaactggagt tcgtggtgct atagaatcct
     3001 tctcagggta tgactgcccc atctgaatca tatgtaagaa taattgtgct actgacagag
     3061 gcaaatgtta gtgactatac atctagtctt taacttcatt taaccctcag tacatcctta
     3121 agttagatgc tctggttcta tttaaggaga aatggagact tagagaggtt aaatggtcca
     3181 tccacactct cctagccact aaaatagtgg ctttaagcat aggttcatct gagggaggca
     3241 caaggctctg ttggaagtct aaacgtgtga ctttcataca tcggcatcag tgccggttag
     3301 ttcccatcgt cagcttgata caatctagag tcacctggga agtgggaacc tcagttgaga
     3361 gattgctctg accaaagtgg tctgtgacca tggctgtgtc tgtgaatagt tatcttgact
     3421 gatgattaca agaaattttg gcttgataag taagcactaa cacttagaga tgattattgt
     3481 tatgccaagc ccactgtggg tgacatcatc cctagcaagt aagcctaggc tatataagaa
     3541 ggctagatga atgtgagcca gggagcaggc cagagagtga gccatcaagc atcattcctc
     3601 caaggtttct gattcaagct cttgccctga tttctcttag tgatgaattt caacctagaa
     3661 aagtaagatg aaatataccc tttcctcccc aagttgcttt tggtcatggt gtttcacagc
     3721 aacaacaaat caaaagagtg tcttactctg ttttgcgggg ctgttacaga atactgtgga
     3781 ttgagcaaca tatagtactt atttccctca gctcagttag aactccaaga acaagacaca
     3841 ggccggttgg gttatatgtt caagctgctc tcttcagtca agttggtgtc ttcttggtgc
     3901 attctacaga ggagactgtg tcctaaaagc ataaggcgag cttcctgaac actgcctcca
     3961 agtatcttat aagggccgtg ataccataac tcatgaagga acagcctcat agcttaatca
     4021 gccctaaaca cttcagctct taatatgcca ttgtgacagc acacctgact tacagaggga
     4081 cctattcaag ccaaaacata gggtcaactt gaattttaga tgagcagcaa tttgtaatag
     4141 aaatatatct caaatattgc atagtatagg cttctaaaat tcaaatttaa ctacaagtct
     4201 ggcattttgc ttgctaaatc tgataatcct gtactgttgt ttttcagtgt caagttttct
     4261 tcatttagtt aacccccaag ccctaaacag cacacccttc agccaaggga gtcttttctc
     4321 ttgccagcta aaaggagggg ggatttttga acgagtctcc ttgccagaag taatcacatg
     4381 aactcagtca gctcacatat ccacacaacg caatcaacaa ggcggccgcc ctgctgtcca
     4441 tccccagccc tggagcactt caaactccag gaatggattt gctgatgaag tgaaacttct
     4501 gggctatcat ggggaccggg gaagacctaa tgatcataac actccttctg ctctgagaga
     4561 gcagacccag aactgcaaag cagaagaaac tccctgagag acaggatggg ggcacatggg
     4621 gtatgggggg aggcactgat aacaaatctg gaactttcca ggttcctggg atgcgatcta
     4681 gtcaacagca agaggcctcc tcccagtctc actggccaca tctgttcaga cagctgtgca
     4741 ctgcctcccc cagggagtaa gaatgtcagg cagaatacaa ttaacacaca caaaaagaac
     4801 attttgtgag cttgtgtacc aggcatagga acattattta atttaatact tcagttgcgt
     4861 tatcaaggtt tccctggtca ctcacaaagg cttaatcaca atcaacctac tcttgatttt
     4921 aaagctgatt ctgcaataga ctccacttag ttgaaccata tgaagctgac gttttcatca
     4981 aacatgactg aatattggca gcttcttctg gcatgaccta agagttatgt ggttgtaatt
     5041 tctctcaact tgttcccaca ttgttaacat agaaataata atggtgtttt cctcacaatg
     5101 tggatgacta ttaaatgaca ttgtgtatat ttaaaacttt agcatcctga cacatgttat
     5161 gtattaaata aaggctgatc gtcctcttcc tctttctctt c
//
