LOCUS       NM_023966               5476 bp    mRNA    linear   ROD 08-DEC-2024
DEFINITION  Rattus norvegicus potassium voltage-gated channel, modifier
            subfamily S, member 2 (Kcns2), mRNA.
ACCESSION   NM_023966
VERSION     NM_023966.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5476)
  AUTHORS   Davies,A.R. and Kozlowski,R.Z.
  TITLE     Kv channel subunit expression in rat pulmonary arteries
  JOURNAL   Lung 179 (3), 147-161 (2001)
   PUBMED   11891605
REFERENCE   2  (bases 1 to 5476)
  AUTHORS   Salinas,M., Duprat,F., Heurteaux,C., Hugnot,J.P. and Lazdunski,M.
  TITLE     New modulatory alpha subunits for mammalian Shab K+ channels
  JOURNAL   J Biol Chem 272 (39), 24371-24379 (1997)
   PUBMED   9305895
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Nov 24, 2020 this sequence version replaced NM_023966.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ296090.1, SRR26643298.39588.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-499               JAXUCZ010000007.1  67907492-67907990
            500-5476            JAXUCZ010000007.1  67908586-67913562
FEATURES             Location/Qualifiers
     source          1..5476
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q22"
     gene            1..5476
                     /gene="Kcns2"
                     /note="potassium voltage-gated channel, modifier subfamily
                     S, member 2"
                     /db_xref="GeneID:66022"
                     /db_xref="RGD:621525"
     exon            1..499
                     /gene="Kcns2"
                     /inference="alignment:Splign:2.1.0"
     exon            500..5476
                     /gene="Kcns2"
                     /inference="alignment:Splign:2.1.0"
     CDS             543..1976
                     /gene="Kcns2"
                     /note="potassium voltage-gated channel subfamily S member
                     2; delayed-rectifier potassium channel subunit Kv9.2;
                     voltage-gated potassium channel subunit Kv9.2; potassium
                     voltage-gated channel, delayed-rectifier, subfamily S,
                     member 2; delayed-rectifier K(+) channel alpha subunit 2;
                     potassium channel, alpha subunit (kv9.2 gene)"
                     /codon_start=1
                     /product="delayed-rectifier potassium channel regulatory
                     subunit KCNS2"
                     /protein_id="NP_076456.1"
                     /db_xref="GeneID:66022"
                     /db_xref="RGD:621525"
                     /translation="MTRQSLWDLSETDVEDGEIRINVGGFKRRLRSHTLLRFPETRLG
                     RLLLCHSREAILELCDDYDDVQREFYFDRNPELFPYVLHFYHTGKLHVMAELCVFSFS
                     QEIEYWGINEFFIDSCCSYSYHGRKVEPEQEKWDEQSDQESTTSSFDEILAFYNDASK
                     FDGQPLGNFRRQLWLALDNPGYSVLSRVFSVLSILVVLGSIITMCLNSLPDFQIPDSQ
                     GNPGEDPRFEIVEHFGIAWFTFELVARFAVAPDFLKFFKNALNLIDLMSIVPFYITLV
                     VNLVVESSPTLANLGRVAQVLRLMRIFRILKLARHSTGLRSLGATLKYSYKEVGLLLL
                     YLSVGISIFSVVAYTIEKEENEGLATIPACWWWATVSMTTVGYGDVVPGTTAGKLTAS
                     ACILAGILVVVLPITLIFNKFSHFYRRQKQLESAMRSCDFGDGMKEVPSVNLRDYYAH
                     KVKSLMASLTNMSRSSPSELSLDDSLH"
ORIGIN      
        1 aagctggggg ggcgcccgaa gaacagaatg acgccccgga acgtcttggg agtctgggcg
       61 gcgactgtgc cccaggctgg agcactcgga gctgtccgtt cagcaccaca gcgcagcgcg
      121 gggctcaggg ccctctgcaa ggcgcaccgg ctcggttccc gcccccgctc cgcgggcgcc
      181 tgcggcgtgg gctcctgtct ctcgtggtgg gtgaggggcg cgcggatcgg aagagggggg
      241 ctccacgagc gttggagcca cgcagccacc tgtgagcctc tcgcggaccc gggcggcggt
      301 gtgtggggcc ggagaccgaa ggaggcgcac gccggacccc gcctgcccgg tggcggtgca
      361 cacacacagg cgcacacatc tacattctcg cacccgcgcg cactcgcgca gccagccagc
      421 ggcggccacc gcggcgatgc tcgccagcag gtttgggaag tttcccgccg gcctcggccg
      481 cgggctccgg tgcacccagg tgtagcgccc ccgcgcggcg cgggcgcctg ggcatctcca
      541 gcatgacccg ccagagcctg tgggacctgt ctgagaccga cgtcgaggat ggagagatcc
      601 gaatcaatgt aggcggcttc aagagacggc tgcgttccca cacgctgctg cgcttccctg
      661 agacacgcct gggccgtctg ctcctctgcc actcgagaga ggccattctg gaactctgcg
      721 atgactacga cgatgtccag cgtgagttct acttcgaccg taaccctgag ctcttcccct
      781 acgtgttgca tttctaccac accggcaagc tccatgtcat ggccgagctg tgcgtcttct
      841 ccttcagcca ggagatcgag tactggggta tcaacgagtt ctttattgac tcttgctgca
      901 gctacagcta tcacggccgc aaagtggaac ctgagcagga gaagtgggac gagcagagtg
      961 accaggaaag cactacttcc tccttcgacg agatcttagc cttctataat gatgcttcca
     1021 agttcgatgg gcaacccctg ggcaacttcc gcaggcagct gtggctggcg ttggataacc
     1081 cgggctactc agtcctgagc agggtcttca gcgtcctttc catcttggtg gtgttgggct
     1141 ccatcatcac catgtgcctc aacagcctgc cagacttcca gatccccgat agccagggta
     1201 accctggcga agaccccagg ttcgaaatcg tggagcactt tggcattgcc tggttcacgt
     1261 ttgagttggt ggccaggttc gctgtggccc ctgactttct caagttcttc aagaatgccc
     1321 taaaccttat tgacctcatg tccattgtcc cgttttacat aactctagtg gtgaacctgg
     1381 tggtggagag ttcgcctacc ttggctaact tgggcagggt ggctcaagtc ctgaggctga
     1441 tgagaatctt ccgaattctc aagctggcca gacactccac tggcctccgg tccttggggg
     1501 ccaccctgaa gtacagctac aaggaagtgg ggttgctctt gctctacctc tcggtgggga
     1561 tttccatctt ctctgtggtg gcctacacca ttgaaaagga agagaacgag ggcctggcca
     1621 ccattcctgc ctgctggtgg tgggccacgg tcagcatgac taccgttggg tatggagacg
     1681 tggtcccagg gaccacagct gggaagctga ctgcctctgc ctgcatcttg gcaggtatcc
     1741 tggtggtggt cttgcccatc actttgatct tcaataagtt ctcccacttt tatcggcgcc
     1801 agaagcaact tgagagcgcc atgcgcagct gtgactttgg ggatggaatg aaggaggtcc
     1861 cctccgtcaa tttaagggac tactatgctc ataaagttaa gtccctcatg gcaagcctga
     1921 caaatatgag taggagttca cccagtgaac tgagtttaga cgactctcta cattagttgg
     1981 gacccaggct tccattgctg atctgctgcc tgtgcttcta gcacagccag aggaatttta
     2041 gggctatggc ctaagaagtc atccgaccct agaggtagca ctgcatggga tataagccct
     2101 agattgcttt tgcaatgttt agagtatttt ttttattttg aggatggtgt atccaaaaag
     2161 atgcctttgc acctttcaat gaaacgacac tcactggtgt ttgcttcata ggcatataat
     2221 gttcatcttc ctgccagatg agtatttaga atgccaattt ctctgttcac tgtgtacagt
     2281 atcctaatgc tcacacccca gtatggcctg tgagctgagt tgtctgtgct cctatttctg
     2341 aggttgctgt atgagttcca gtgagaacgt atctgtctat gagggcagca aggctatcat
     2401 gagatttgga tcacagccat gtgaaaataa tctcggttac gtatcctgtg ctttcattta
     2461 cccttaatac caaaacagag agagagcaaa gcacacctga ccaatgcaag tcttcaagtt
     2521 gtctttctgc ctggtcctgt cctagtgatg tgcatgagtg cacccgtctt cttacagaaa
     2581 gatgtggact gatgtgtatc tcctaagtgt cagtgtaaga gaatgtaact cagtcaatat
     2641 gtagtaaaga ctgaatgttt tccccctaac agataagtct aggggcaggg actttagctg
     2701 aacatggact aaaccccagg atgctgtaag cagagttcat gtaggctaaa cccttttatt
     2761 gatggtcagg cctctttttt cctgggggaa ttacagagac atttatttct ggctgagatt
     2821 cttaatccag gccattttga ccaaagtctg tgtcttggta gtagcatgtt tttcaagcat
     2881 ttccttttta agatgtttag gaataaggtt gtgctgtctt tctccactag aagaggttag
     2941 tgttttgttg tttttgtgta gtaagcactg ttaggttgct ggcgagggca gtagcttaaa
     3001 ccttttcttg tctgctctga aagcccataa aatgaatgct cttttgtttc tgggcagagt
     3061 ttgctttagg tagttttgct tgtaggacac aggatagtat atgcacaggg tttcctgttt
     3121 cctgctgtgg aaaacataag tacagaagca gattcaacat acaagcacgc acgaaggcag
     3181 tgtgtttacc cagggtggaa acactgcagt ttttattctc attgcaattg cagtggggct
     3241 tggggagggc aggggtagag gtcagaagaa aagagttata aagccaaaaa ctgctactgt
     3301 atacaatata agtaactgtg agtttcttta aaggcttaaa actagtctta aaaaacaaaa
     3361 acaaaaaaac aaaaaaacaa aaaaaacaaa aaaactcctt tcaaccaacc attaagctgt
     3421 gttgaagggt tatctccatt ccctttccaa acactccatt cagttagcac aaaacattat
     3481 gaaggggaac ccttttaaga taattctttc ccatcatctc ctaagtaatc tgatggtttt
     3541 ccagtggctt tcgttattgt tgcgtctttg gcaaggctat agaatccagg gatccaaata
     3601 tggagataaa caggctttta atccaaagtt tgggcctact cttaattggt ccattttgtg
     3661 ttttagttgg tcaaggataa tccacacctc agagggcttt gtgtactagt agttgccatg
     3721 gtgactacag tgtgggcgat ttgttggatg aatgcactgg ccatttaatg cccttgagct
     3781 tccagttcag atctttcacc agactggagg ctcaatgagg ggcagcgggt ggcaacctcc
     3841 tagtgcctac gtgcagacac atctgtctct tattccaaag cagcagggat gtgaagtgac
     3901 ttccggaagg aaccccaccg tgaaccggaa ggaaggggtt ggtttgggga gtttgcacac
     3961 ggaactcttg ttgttggatg gatcttcagc cctggaaaga ctatgcattt ataaaactgt
     4021 acccagctgc actggtgtca ggggacatcg taaacctgtg aggactgttc agtttgctga
     4081 ggctgatggt atactgtaac tgagcatgat atccatggtc actcactgac catgaagttg
     4141 atggaaagaa gaaataggca agaggcagaa taacttagcc actctcctga ggattttttc
     4201 taaatgaaca tgtttaacac caaaaaagag ttacctctag tgcgtaccta caaggatatg
     4261 aaagctggaa aacttgactt ttcttttttt ggtaacgact tgctttatct ggtgcctttc
     4321 attgggggaa tcccaaagtg ctttagaaac tgtcttttta acatttcttg tacatatatg
     4381 tatacttgta aaagaatatt cctttgccca ccaagattta gttgcttctg agcatgaaaa
     4441 ggtcccagga gcattgattc cccaagcagt ggtttcagag accttgaggg agagcagccc
     4501 agatagctgg ggatctgcag tgattcccat agaccataaa gaagggtata agactctggg
     4561 acctttccct tatcactgaa ccacatgaag gtatgaagtt cacaagtcct agacagacac
     4621 aaggcctctg tttagccaag ttaggtaatg tctcccacgg tagtttcttg gtaaccaggg
     4681 gagggcagat tcatttttct gccctattct tgggaataac ggctacaaag ccgaatcgag
     4741 cccacagact atcaaagtag cctgtacaat tctttcttgg ggaaacagag tagaaacagg
     4801 ctcgctcatg cctagctggt ggctgaaact ccactcctgg gatttgacct gttcgatatt
     4861 cctgggacaa atacatgggc ggagcttcct caaagcatgt gggatggaca tttggaagtg
     4921 acacatgttc atcgcacaga tacattaacc ttgggctgtg tttcccatca aagccctgcg
     4981 cttcccaggt tagctgctga ggagggtcgt gtagagtgct gagcttatgc ttagctcatc
     5041 aggtcgtaat tgatgtttaa tatttggatt tgttatttct tcttactgta gcactcaaag
     5101 caccgagcta cctgttaatt cctgcttcgt ttcaatggaa gtgatttgtt ctgcactttg
     5161 ggagagcggc gatggggacc acaggctgtg tggtctctgc ttggaggctt aactggtatt
     5221 tcttgtatgt tttaacagca tgacttgttc cagagttgta attttaaaca tcgagaacac
     5281 tgtatttgcg atgtcagttt taacactcgt taacacacta ccgtgccagc gtcctggcag
     5341 ccccacacca ccattatgtc ggctgctgtg cttgagtttc ctgtgcctcg actccagagt
     5401 gaggcaaatg actgacatgc tcagaatgcc agccttgcaa atgtgcagat taaacagaaa
     5461 acaattattt cacttc
//
