LOCUS       XM_039102982           10226 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus potassium calcium-activated channel
            subfamily N member 3 (Kcnn3), transcript variant X1, mRNA.
ACCESSION   XM_039102982
VERSION     XM_039102982.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051337.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10226
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..10226
                     /gene="Kcnn3"
                     /gene_synonym="KCa2.3; SK3"
                     /note="potassium calcium-activated channel subfamily N
                     member 3; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 mRNA, 21 ESTs, 4 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 62 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:54263"
                     /db_xref="RGD:2964"
     CDS             345..2444
                     /gene="Kcnn3"
                     /gene_synonym="KCa2.3; SK3"
                     /codon_start=1
                     /product="small conductance calcium-activated potassium
                     channel protein 3 isoform X1"
                     /protein_id="XP_038958910.1"
                     /db_xref="GeneID:54263"
                     /db_xref="RGD:2964"
                     /translation="MDTSGHFHDSGVGDLDEDPKCPCPSSGDEQQQQQQPPPPSAPPA
                     VPQQPPGPLLQPQPPQLQQQQQQQQQQQQQQQQQQAPLHPLPQLAQLQSQLVHPGLLH
                     SSPTAFRAPNSANSTAILHPSSRQGSQLNLNDHLLGHSPSSTATSGPGGGSRHRQASP
                     LVHRRDSNPFTEIAMSSCKYSGGVMKPLSRLSASRRNLIEAEPEGQPLQLFSPSNPPE
                     IIISSREDNHAHQTLLHHPNATHNHQHAGTTAGSTTFPKANKRKNQNIGYKLGHRRAL
                     FEKRKRLSDYALIFGMFGIVVMVIETELSWGLYSKLFVIDNGADDWRIAMTYERILYI
                     SLEMLVCAIHPIPGEYKFFWTARLAFSYTPSRAEADVDIILSIPMFLRLYLIARVMLL
                     HSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCE
                     RYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVA
                     VVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVR
                     KHQRKFLQAIHQLRGVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQI
                     GSLESKLEHLTASFNSLPLLIADTLRQQQQQLLTAFVEARGISVAVGTSHAPPSDSPI
                     GISSTSFPTPYTSSSSC"
ORIGIN      
        1 cttgccatat aacagtgtca ggaggaggag agcgaagcga ttgagccagc gaggagtgaa
       61 gctgagtctg cctcatacac tcctagagga ccgccttcag aatagagttc ttttcgcccc
      121 ttcctccttc tcccagctcc tctcctggct tttctatccg cccaatacaa tgcacactcg
      181 agtggcagcc ccagagaact gaagcaaacc aaagagagag gactggagcc aagacacttc
      241 tggtggggaa gcttggatgc ctggctttct ttgaggtcat ctttggaacg agggtggctt
      301 tggggtggag ggtcgtgctg cagggaaccc agccaggccc caagatggac acttctgggc
      361 acttccatga ctcgggggtg ggggatctgg atgaagaccc caagtgtccc tgtccatctt
      421 ctggggacga gcaacagcag caacagcaac cgccaccacc gtcagcgcca ccagcagtcc
      481 cccagcagcc tccgggaccc ttgctgcagc ctcagcctcc gcagcttcag cagcagcagc
      541 agcagcagca gcagcagcag cagcagcagc agcagcagca ggctccactg caccccctgc
      601 ctcagcttgc ccaactccag agccagcttg tccatcctgg tctgttgcac tcttctccca
      661 cggctttcag ggctcccaat tcagccaact ccaccgccat cctccaccct tcctccaggc
      721 aaggcagcca gctaaatctc aatgaccact tgcttggcca ctctccaagt tccacagcca
      781 caagtgggcc tggtggaggc agccggcacc ggcaggccag ccccctggtg caccggcggg
      841 acagcaatcc cttcacggag atagctatga gctcctgcaa atacagcggt ggggtcatga
      901 agcccctcag ccgcctcagc gcctctcgga gaaaccttat cgaggccgag cctgagggcc
      961 aacccctcca gctcttcagt cccagcaacc ccccagagat tatcatctcc tccagggagg
     1021 ataaccatgc ccaccagact ctgctccatc accccaacgc tacccacaac caccagcatg
     1081 ccggcaccac tgctggcagc accaccttcc ccaaagccaa caagcggaaa aaccaaaaca
     1141 ttggctataa gctggggcac aggagggccc tgtttgaaaa gagaaagcga ctgagtgact
     1201 atgctctgat ttttgggatg tttggaattg ttgttatggt gatagagacc gaactgtctt
     1261 ggggtttgta ctcaaagctc tttgtgatcg acaatggtgc agatgactgg cggatagcca
     1321 tgacctatga gcgcatcctc tacatcagcc tggagatgct ggtgtgcgcc atccacccca
     1381 ttcctggaga gtacaagttc ttctggacgg cacgcctggc cttctcctac accccctctc
     1441 gggcagaggc tgacgtggac attattctgt ccatccccat gttcttgcgc ctatacctga
     1501 tcgcccgagt catgctgcta catagcaagc tcttcacgga tgcctcatcc cgaagcatcg
     1561 gggccctcaa caagatcaac ttcaacaccc gattcgtcat gaagacgctc atgaccatct
     1621 gcccgggcac ggtgctgctg gtgttcagca tctctctgtg gatcatcgct gcctggactg
     1681 tgagagtctg tgaaaggtac catgaccagc aggacgtaac tagtaacttt ctgggtgcca
     1741 tgtggctcat ctccatcacg ttcctttcca ttggctatgg ggacatggtg ccccacacat
     1801 actgtgggaa aggtgtctgt cttctcactg gcatcatggg tgcaggctgc actgccctcg
     1861 tggtagctgt ggttgcccga aagctcgaac tcaccaaagc agagaagcat gtgcacaact
     1921 tcatgatgga cactcagctc accaaacgga tcaagaacgc tgccgccaat gtcctccggg
     1981 aaacatggct gatctacaaa cacacaaagc tgctaaagaa gattgaccac gccaaagtca
     2041 ggaaacacca gaggaagttc ctccaagcta ttcaccaact gaggggtgtc aagatggaac
     2101 aaaggaagct gagtgaccaa gccaacaccc tggtggacct ttccaagatg cagaacgtca
     2161 tgtatgactt gatcacggag ctcaacgacc ggagtgaaga cctggaaaag cagattggca
     2221 gcctggaatc caagctggag cacctcacag ccagcttcaa ttccctgccc ctgctcatcg
     2281 cagacaccct gcgccaacag cagcagcagc tgctcactgc cttcgtggag gcccggggca
     2341 tcagtgtggc tgtgggaact agccacgccc ctccctctga cagccctatc gggatcagct
     2401 ccacctcttt cccaacccca tacacaagtt caagcagttg ctaaataaaa ctccccactc
     2461 cagaagcatt acccataggt cttaagatgc aaatcaactc tctcctggtc gctttgctgt
     2521 caaggaagtt tcagaccagg gaacagaacg aagagagatg gagcgatgag ccgactcatg
     2581 ttctttcagc gtgctttgtt cgatatgcct tgaaaccaga aatctaatct ctgtttaggt
     2641 gcctctactt gggagctgga agaggaggtg acgggaagca acgcctctgt cagggccctt
     2701 gctgcagagt tggcggagaa cagaaatccc tgctcaatct caggttttca cagggaggtg
     2761 ggggaggggc agccactctg aagcagagga gagggaagcc agccaaagag gggtgtgctg
     2821 ggcaagggtg gtatgaggtt tggggaatgg gttcctggtt gccttgggac cacagcacac
     2881 ctatcctttt gtctaaggaa gcctctgggt ggtaaaaata aaacagagct acccagaact
     2941 ttccaaaatg gacataccca aattagactg gggaggaggg tgatggagac aaataaaaag
     3001 ccagaatttc catccaatga tacgatccaa catatataca cacagatgtt caatccaggt
     3061 ccttttctgt ttgaattgag cccaaatgaa agggacctgg tacttcgcct tgcacacagt
     3121 aagcaagctc taattccgca ttgagatgat gtgtggggtg tgttttgttg aggaagttag
     3181 cggggattgg ccatattctg agcttcactg aagatgcagg tccctccctg acagtgtcct
     3241 ggttacccat gctgcctgat tcaagtgtag gccaagcccg cactgttggc attgtggaga
     3301 gataagcagc cttctaaaaa caaacaaaaa caaaaaaaag acagcttttg aagaattttc
     3361 tcccagccag ataatctgtg tgcccttgga acccacgttc ccaggtgtct gtgtgtagga
     3421 gaggaggaga caagtatgct cagtgccccc atagtgaaca ggactgatgt ctggggcgct
     3481 gtcaaagcat cttcacccgg cagcaggctc cggccagaca tgtaagagta cggaaggatc
     3541 agtgcctaac cctgctaggt tgggaggaga agggtgggga gtggctcctg tggccccttc
     3601 taccttacct gacatcatct caaaaatgaa acactgtgag aacacaaggc gccctaggga
     3661 cacttgtgtg taaagtgaga ggacacattt gttagaagcc tgtcctattg tgccacgttc
     3721 atcttggggt aaaacctact ccactgaatc tcagactcca agagactcca gagagaagca
     3781 gacccagtat aaggacaggc actccccacc cccacccccc attgctccgt gatctgaccg
     3841 cacacacagc cgtgcgggag agctattgag tcacctctca tttctccatc cagaggtctt
     3901 cgatttctgc ttataagaaa ttatatgtgg aacatttcat ctatcttttg gtaggcccaa
     3961 aggacgttgt ctgtgtatag ttgctgtccg gagagtagtc ctgtggcagg ttaccacagc
     4021 cccctggagg tatcgcctta ctctgtgcgt ttctcttgtg cactgctggg cctggtcctt
     4081 tcaggacagg gaaattgctg gacatcaagg cagacaactg tggcctggag gacatgcctt
     4141 ggttttttgt ttgtttgttg ctaagtctct tgtttgtctt tccgccttgc tgctgctgtc
     4201 tgtaccttgt ttctgcagtg ctggagagca ggctcgcggc ttcctgcatg ttagacaagt
     4261 gctgttccac tcaaccacac cccagcctac tgctgttgtc ttaatggcct atcctcttaa
     4321 tggtctatcc tgatcgctcc ctcgagcatt ttcattagct gttttgcaca ccagagaggc
     4381 cacatttgtc gttagcattt aattcttttt acttgttctt ttaattatta attatctgaa
     4441 agattatttt tatcccgaga atggtatccc tgttttcagt ttgaccgtac ctacaggcag
     4501 acgtgcagac agaggaaata ggcatgtacc ttctttgtgt cactgtttgc atttgacaaa
     4561 atgagggctg ctgatgggcc cacctcctcg tcatttgacc tacagccctc aagtgtttcc
     4621 tctgctctct gttgccgctt gctctgatcc tgtgctgtgt ggccatagca tggcacctct
     4681 aggatttagt tcccatttca cacaagtgac acgcaagatc ccaccacttc tcctgccatg
     4741 tatcaatccc ggacatagtc taaaatctgt ccttttgttt ttattcttgc ttagtaaacc
     4801 ctgaaggcca agctagaaat gcttcaagag gatggctaga actgtttcag gagggtacca
     4861 ctagcattag agagacacat gggcctttgt agggtggctt ggcccactgg tattgcaata
     4921 ggtctgggtg gtcttattgt tagcaaaaga atctacctcg agaaacgtga caggatcaga
     4981 aggctggctc tgtgagggta aatgaagtgc tgcttcttcg ccctactatt tccctaatat
     5041 gagggaagtg ataattctct tgcaaatata ttgacccttg atgacctagg tattgaggac
     5101 cctggctagc tcgcccagat gtatccttgc atcttttaga tgatcccatg tcacctaagc
     5161 atctcagttg agctaggaag gaggctagtg ggtgctcagg ctatgtggta gtgggagagg
     5221 tctgagtctc aggactgggc tgcaatttaa aaccatgaat tactgtaatt tcgctctagg
     5281 cctgaactgg tccagttctg ctcactccta gaaggctgac cagtgacaga ggccctcctg
     5341 gcatcttccc aggaatgcag tagcagacag aagcactcca acatatcccc aaatatctgg
     5401 acacttgaat gaaaactgta gagccaccgt gtcattgctt aagccatatt actgcttcag
     5461 gtactgtgga gtcagggatg cactgtgata ctccaaggcc actgagctca gtgggatttc
     5521 aggacatagc atcagttggt aatttacgcc tgactagaag ctcatttctc cttagattga
     5581 catccaaata agaatctgca cctttggctc aaaggccacg tgtgtgatca ccatcaataa
     5641 accatcatga agtgtttgtg agccattctt accacctgca taatgtagaa ctccatgaca
     5701 tcatgcctcg agatatgacc caaatgaatg agaggggcta tagccatgca tcagcaggga
     5761 ctgtgacccc ggcagggtcc tacactgaga cagcaacctt gtaaattaga agatgtagaa
     5821 actgtacgtg aaagttagcc cccaagtgct gggaaagtta ttaaaggcca agaggggaca
     5881 gcgcagcctt gacaaataat gattttaatg tatccagagt ttccccttcg ctttgcagta
     5941 acttccttgc aaagaagtca tggaaagaag aaaactagtg acacaaaaat cagaataggt
     6001 aaaagcctga gactggagtc acatatccca ccaatatgtc tcagtttgcc tgtatttaaa
     6061 agtgaagatg agttaatatt aagttcaaag tattcagtag aagacaaaag gtattgcttg
     6121 actgactagc taacccgcac ttagatgtta catttgaatg tagtgatagt taccaaaagg
     6181 taattactgc acaggggata ggtagcgatt tgcagggaga accatggggt ctgtgcacag
     6241 ttcaggaagc ccccctcctc cggaggatga taaacagtgt atctcaaatt aagagtcagt
     6301 gtttcatctc caaatagaca ccctggctag agctagagaa acccccgctg agacactgtg
     6361 ataccattgt actgccagca ggtcagaact ttccaaacta ctgcttttaa atgctcaaat
     6421 aggttcccac ttcatccagt cactctactt cccccaaagc tactagaagc agattaagga
     6481 tccattagtg gtcatttcgc tgtccccgtt gacttcatgg tctttggttt cagtccttta
     6541 gatggctatc tggaggcttc ctggcagaca tgaacagttc gttctctccc ctgtagccag
     6601 ctggcttgtt cacgccttgg acagtatctc ttccttcttc actactgcca aagcaaacat
     6661 ttggggaatg ggattatagc tagccctaag acgggggcag gggggatgga gggtagtgat
     6721 agtgtctgcc tatagtaata ggaaacttgc accaggctgt atgaatagtc accaacggta
     6781 aacttctgcc agacaaggaa tgtgtagact tccgttgaaa taggccacag cttataaaca
     6841 tgtgttctgt gcagtggtct gtagacaacc acagaggggg atgtaactgt gatctttttg
     6901 tcttacacca ttactggaaa cgcccacaca tgaactggag ttccctcgga acaacattgt
     6961 caaatcttca acagacgacc tccgaaccag gtgccacgag ccctgcaaca gctgtttaca
     7021 cactgagaac catattctgg aagctgcaac cttgggcctg gactgacaag agacctgtaa
     7081 ccaatcaagc tggtggagga aaagcacaaa ttcaatacca acctctagtt aagatcccaa
     7141 agagatgctg acatttctgg caaaaataaa taaataaata aataataaat aatatataaa
     7201 taggaacagt gacaaataaa aaagtgaatc tgattggaac agctgacatc cagcttccca
     7261 gagggaggac ggggctaagt gacattctcc agctgtgtta cttttcggat cccaaccaga
     7321 gctgatccac cttcgtcata catggtgttt aatggcgcaa gagtgcaatc aatttagtcc
     7381 cagactctcc attctgtgct ggccacaaga gaacaagaaa cctgagagat aggatgttga
     7441 tggaggaacc gttttcatag caaactcaga aatggaggtg tttatattcc aaaccagatg
     7501 ggcttcagta tgaatttgca tcttgcctct gtactgcttg ctatttttta atgataggag
     7561 aaagcataac agtttatttt aaatatgaaa tatattgcta tattataaaa tatattgtaa
     7621 ctttcgatta acattttgta ttgagctagt ctttagcagg ttgggtgaca gcctgccttc
     7681 ctaatgactg tttctgagta cacatcattg ttagcggttg cctgatcccc aaacccaggg
     7741 tcctggttct gcagcacgcc agacggccat attctcattc cctaagtctg agcagtaggg
     7801 acaaaaatag ccctgaggtg agcatggaag aataattcca ctctaaattc tatcaagcca
     7861 tttcagaagc gatttgtaaa gctgtccctc cttgagtagc cactgacagt ttagtaaatg
     7921 ctagactctt tctatctaaa tgcaaacggc ccattctgta agttagcctc aggcatagcc
     7981 gaccagctct cctctggcaa tatcagaatt gggcattaaa aagagtcttg tttactttgc
     8041 ctcaaaatac tcaaaattct aagcatcaag tttctctata taagagggca accaagatta
     8101 gagttctctc cgggcccagt gagaactgga ggtggaggtg gaggtgtgct tctctgagtt
     8161 ggcgatctct tggagggggg catggttcag gaaggggaag atcaaggctt ctccagtttg
     8221 tcattggtgc tggaggagga ggcaggatgt gcacagcaag actcagtaaa gagccagttt
     8281 ccttgtttgc tattcactgt agcgagggga agatggttct gaatatcaca tttcctctta
     8341 tggcaagaat aaacagctca tgaaacccac tccctccttc tcgctacagt acctgagata
     8401 tacgtgtaga gttacagagt tccttcctct gaattgccag ggtcctattc tatattaaag
     8461 tggatgaagg atgtcttccc taaatctgcg catctccgat gaggacctta cttcccggca
     8521 tcacttctgc acagcacagg acaggcgcag accaagtagc atcaggggag agttacctgc
     8581 ctgcctcttc ccttcacaaa ccctggagat gcacacagat ccacagacca tgcaaaaccg
     8641 taggtgctgc tctgggaaag agactagaag cctctaagtt ccctaaactt cagcccataa
     8701 tgcctgttag tcataccaat gacagacaac gtttctaaac attcaatcag ctggagtatc
     8761 cagggctgtc tgtgtgaaca aatcgcgtct gcttctctca gcatctgaat tactcctcag
     8821 ttatgtgcta ggctgagctc cattaaagcc atcagaactc cagggcacct gtttttaaca
     8881 cattacttac tcactgagca atggaaatga gctaactctc aatttggtaa ttgactgaga
     8941 gacattgatt tgtttcttta tacatctcct actccaaatg gagctatttt ggctgtttct
     9001 tctagtgatc tatagactgg ctaagatgtt tacaggtata gagaagacat atattctggc
     9061 ctttcccatt taaaatgtaa ctcatccaca atcaaagaaa ctgagccaga tccctgattt
     9121 ggcggaagca agctctgggc aataattcat gtgtggtgtg tagccatatg ctaatccttg
     9181 ctactccagg tgagagccaa aagccggcag cattcacatc ccccacacac ctgttagaag
     9241 caggctccgt gccaagccca ctcaatcaca attggcattt taaccagagc tcctggtgat
     9301 ctgtaagcaa ccaatactga gacacgctga cctcaccaca ctgcagtggt aaccaataat
     9361 tcagctattt cttcctccaa tctcaagtta ccaaactgtt ggatgataga cagctctgac
     9421 aggatttcaa ggataaagat gggtgtatca taaaattcca cgtggtattg cacagtttac
     9481 atgatataca tgaactataa tgtcaattgg aggtggcctt tctctagtct gatgtgaaaa
     9541 actgctcaag tcacagcttt gagccacctc gaagccttca gactataagg tggagccatg
     9601 acaagtccct ggatagaagt tcctccttag catactgcag aaatgggaca tttctggtcc
     9661 tctgtccctc caggagaaag ccagcatctc ccagtgagga ctctcctctt ggggactaga
     9721 aaaaaaaaaa ctcagttcag ccattccgac acattcctaa tctcctgagg gttctccttt
     9781 ttgttgtgtc aagcaaggtg gacaaggaga gatgtgaatt ctgatattgg caccctaaat
     9841 tgatatgtac ccagaaacag ttatgttcta aattaatggc tttaacctgt tcattgtaaa
     9901 aagtgccttg gacttcaatc taaagaggtc agtataaata tgtatgtgtg tgtgatgtgt
     9961 atgtaggcaa atatttacat atatatacat acacaggtgc atacacatat acctgcacat
    10021 tcatatataa tatatacata catatataaa tgcttcataa tatatcatat tgctaatcac
    10081 agcttcttat tttgtttggt tctatgttta tttgtttagt gagatcttta catagaaagg
    10141 ttctattcag gacatggatg tattttttgt ttgtttttta ctttttatta aaaaggtaaa
    10201 ggatattaaa agataaaaaa aaaaaa
//
