LOCUS       NM_001104560            1637 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus potassium calcium-activated channel subfamily M
            regulatory beta subunit 3 (Kcnmb3), mRNA.
ACCESSION   NM_001104560 XM_001066117 XM_227040
VERSION     NM_001104560.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1637)
  AUTHORS   Hiraizumi,Y., Nishimura,I., Ishii,H., Tanaka,N., Takeshita,T.,
            Sakuma,Y. and Kato,M.
  TITLE     Rat GnRH neurons exhibit large conductance voltage- and
            Ca2+-Activated K+ (BK) currents and express BK channel mRNAs
  JOURNAL   J Physiol Sci 58 (1), 21-29 (2008)
   PUBMED   18177544
REFERENCE   2  (bases 1 to 1637)
  AUTHORS   Brenner,R., Jegla,T.J., Wickenden,A., Liu,Y. and Aldrich,R.W.
  TITLE     Cloning and functional characterization of novel large conductance
            calcium-activated potassium channel beta subunits, hKCNMB3 and
            hKCNMB4
  JOURNAL   J Biol Chem 275 (9), 6453-6461 (2000)
   PUBMED   10692449
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB297662.1.
            
            On Aug 31, 2012 this sequence version replaced NM_001104560.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB297662.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1637              AB297662.1         2-1638
FEATURES             Location/Qualifiers
     source          1..1637
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="W"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q24"
     gene            1..1637
                     /gene="Kcnmb3"
                     /note="potassium calcium-activated channel subfamily M
                     regulatory beta subunit 3"
                     /db_xref="GeneID:310303"
                     /db_xref="RGD:1311852"
     exon            1..322
                     /gene="Kcnmb3"
                     /inference="alignment:Splign:2.1.0"
     CDS             261..980
                     /gene="Kcnmb3"
                     /note="maxi K channel subunit beta-3; calcium-activated
                     potassium channel subfamily M subunit beta-3; potassium
                     large conductance calcium-activated channel, subfamily M
                     beta member 3; potassium channel subfamily M regulatory
                     beta subunit 3"
                     /codon_start=1
                     /product="calcium-activated potassium channel subunit
                     beta-3"
                     /protein_id="NP_001098030.1"
                     /db_xref="GeneID:310303"
                     /db_xref="RGD:1311852"
                     /translation="MQPFSIPVQITLQGGRRRQGRTALPASGISNGDPLKVHPKLPSS
                     AGEDRATLLGIAMMASSVLMFFLLGTTVLKPFMLSSPREESNCTTVHTHIADDWLDFA
                     FTCEGSCQGQGTYPCLQVFVNLSHSGQKVLLHYDEEAIRTNPKCFYTPKCHGDRDHLL
                     NSALDIKEFFDHNNGTFPCFYSPDGPLGVVLRKSGHKVVFHCLFWPLLTLLGGALIVG
                     LVRLTQHLSFQCEKYRAVVRA"
     exon            323..496
                     /gene="Kcnmb3"
                     /inference="alignment:Splign:2.1.0"
     exon            497..695
                     /gene="Kcnmb3"
                     /inference="alignment:Splign:2.1.0"
     exon            696..1637
                     /gene="Kcnmb3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggctgtagaa ccacccaagt cctccatgag catctactct tgagctctgc ctttcggcca
       61 ggctgcctga gttcccacct ctttaggaaa cttctagagg cccggcagat ctagatgcag
      121 caggggtcct gatggctgtg gctaggcagg gagttgggaa ctccctctgg gactccactt
      181 ccgatgatgc gtaagcttcc tgagcttgca aagggcacat cccaggcgag gagcatccga
      241 tccagccagc ccgtggcctc atgcagccct tcagcatccc ggtccaaatc acactacagg
      301 gtggtcggag gcgccaaggg aggacagcac ttccggcctc aggcataagc aatggagatc
      361 ccctgaaggt gcacccaaaa cttccatcga gcgctggtga ggaccgggcc acgctgctgg
      421 gcatcgccat gatggcctcc tccgtgctga tgttcttcct gctggggacc actgtgttga
      481 agcccttcat gctcagctct cccagagaag aatcaaactg caccactgtc cacacacaca
      541 ttgcagatga ttggctggac tttgccttca cctgtgaggg tagctgccag ggccagggga
      601 catacccttg cctgcaggtg ttcgtcaacc ttagccactc gggacagaaa gtgcttctcc
      661 attacgatga ggaggccatc aggaccaacc ccaagtgctt ttacacaccc aagtgtcacg
      721 gagacaggga tcatctgctc aacagtgccc tggacatcaa ggaattcttc gatcacaaca
      781 atggaacttt cccctgcttc tacagtcctg acgggcccct gggagtggtc ctgaggaagt
      841 ctggccacaa ggttgtcttt cactgcttat tttggccttt actgacattg ctgggaggcg
      901 ctctgattgt tggtttggtt aggctaacac aacatctgtc ctttcagtgt gaaaagtata
      961 gagcagtggt aagagcttaa gcaggagcta gaacacatcc tgcgggctgg cgcaggtcta
     1021 cactgtacag tgtggcaaag agtcagggaa ggaacagaga gaactgaaga gggaggtccc
     1081 acctctccag ttccaagatg ctccagatga agacttgacc actgccaggc agacttgtga
     1141 tcccagccct tgggaggcag aggcaggagg atcaggttca aaggcaacat actggggttg
     1201 aagagtattc ccaggccctg ggtttgagcc ccagtactag aaacaatcat atctgcttac
     1261 agacctgctg tgtgagggca aaggcacagc tttccacacg agaacgtctt taaatgttga
     1321 ccattttcta ttaattctaa acaatatgta ccgtttcaac agtttttcca atctccttca
     1381 cacaagccat ggaagcagtc ttctcctcat aggcaaaatt aattcaaggc aggtctttat
     1441 gtgacttaag ctctccggca ggggagggta acaagccact gctgagtctg tctgtccaac
     1501 acttagcagc tagcttatga ggttcacatg aaaacatttc tcacaggaaa aaaaaatatt
     1561 aggagctggg gagatggctc agttggtaaa acatttgcag tgcaagcagg attacctgac
     1621 ttgtcagaca cattaaa
//
