LOCUS       NM_170718               2649 bp    mRNA    linear   ROD 13-FEB-2025
DEFINITION  Rattus norvegicus potassium inwardly-rectifying channel, subfamily
            J, member 14 (Kcnj14), mRNA.
ACCESSION   NM_170718
VERSION     NM_170718.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2649)
  AUTHORS   Pruss,H., Derst,C., Lommel,R. and Veh,R.W.
  TITLE     Differential distribution of individual subunits of strongly
            inwardly rectifying potassium channels (Kir2 family) in rat brain
  JOURNAL   Brain Res Mol Brain Res 139 (1), 63-79 (2005)
   PUBMED   15936845
REFERENCE   2  (bases 1 to 2649)
  AUTHORS   Pruss,H., Wenzel,M., Eulitz,D., Thomzig,A., Karschin,A. and
            Veh,R.W.
  TITLE     Kir2 potassium channels in rat striatum are strategically localized
            to control basal ganglia function
  JOURNAL   Brain Res Mol Brain Res 110 (2), 203-219 (2003)
   PUBMED   12591157
REFERENCE   3  (bases 1 to 2649)
  AUTHORS   Topert,C., Doring,F., Wischmeyer,E., Karschin,C., Brockhaus,J.,
            Ballanyi,K., Derst,C. and Karschin,A.
  TITLE     Kir2.4: a novel K+ inward rectifier channel associated with
            motoneurons of cranial nerve nuclei
  JOURNAL   J Neurosci 18 (11), 4096-4105 (1998)
   PUBMED   9592090
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Dec 2, 2020 this sequence version replaced NM_170718.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.990506.1,
                                           SRR26643298.2948.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760393,
                                           SAMEA5760433 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-133               JAXUCZ010000001.1  105437126-105437258 c
            134-895             JAXUCZ010000001.1  105432646-105433407 c
            896-2649            JAXUCZ010000001.1  105429607-105431360 c
FEATURES             Location/Qualifiers
     source          1..2649
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..2649
                     /gene="Kcnj14"
                     /gene_synonym="IRK4; Kir2.4"
                     /note="potassium inwardly-rectifying channel, subfamily J,
                     member 14"
                     /db_xref="GeneID:276720"
                     /db_xref="RGD:628872"
     exon            1..133
                     /gene="Kcnj14"
                     /gene_synonym="IRK4; Kir2.4"
                     /inference="alignment:Splign:2.1.0"
     exon            134..895
                     /gene="Kcnj14"
                     /gene_synonym="IRK4; Kir2.4"
                     /inference="alignment:Splign:2.1.0"
     CDS             188..1492
                     /gene="Kcnj14"
                     /gene_synonym="IRK4; Kir2.4"
                     /note="inward rectifier K(+) channel Kir2.4; potassium
                     channel, inwardly rectifying subfamily J member 14;
                     potassium inwardly-rectifying channel J14; inwardly
                     rectifying potassium channel Kir2.4; potassium
                     voltage-gated channel subfamily J member 14"
                     /codon_start=1
                     /product="ATP-sensitive inward rectifier potassium channel
                     14"
                     /protein_id="NP_733836.1"
                     /db_xref="GeneID:276720"
                     /db_xref="RGD:628872"
                     /translation="MGLARALRRLSGALEPGNSRAGDEEEAGAGLCRNGWAPGPVAGN
                     RRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLF
                     GLTFWLIASLHGDLAAPPPPAPCFSQVASFLAAFLFALETQTSIGYGVRSVTEECPAA
                     VAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDRRLCLMWRVG
                     NLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEI
                     DSASPLYELGRAELARADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLF
                     QRGSQYEVDYRHFHRTYEVPGTPVCSAKELDERAEQASHSPKSSFPGSLAAFCYENEL
                     ALSCCQEEDEEEDTKEGTSAETPDRAASPQALTPTLALTLPP"
     exon            896..2649
                     /gene="Kcnj14"
                     /gene_synonym="IRK4; Kir2.4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agaggttgag tgtccggctc aggcccccag gggccgagga cagacctgaa tacattagca
       61 cccacagagg cccctctcca gcctgagcag aggaaccccc agtgcaggga atgggggtgg
      121 gcggcccccc caggtttggg gcgcctgccc cccgctagga caaatctaga gggggtctcc
      181 ccacctaatg ggcttggcca gggccctgcg ccgcctgagc ggcgcgctgg agccaggaaa
      241 cagtcgagct ggtgatgagg aggaggcggg ggccgggctg tgccgcaatg ggtgggcgcc
      301 tgggccagta gctgggaacc ggcgccgtgg acgcttcgtc aaaaaagatg ggcactgcaa
      361 tgtgcgcttc gtgaatctgg gtggccaggg cgcgcgctac ctaagtgacc tgttcaccac
      421 atgtgtggac gtgcgctggc gctggatgtg cctgctcttc tcctgttcct tcctcgcctc
      481 ctggttgctc ttcggcctga ccttctggct catcgcctcg ctgcacggcg acctggctgc
      541 cccgccacca ccggctccct gtttctcgca agtggccagc ttcctggctg ccttcctctt
      601 tgcactggag acacagacgt ccataggcta tggtgtgcgc agcgtcaccg aagagtgtcc
      661 agctgctgtg gccgctgtgg tgctgcagtg catcgcaggc tgtgtgctcg acgccttcgt
      721 cgtgggtgca gttatggcca agatggccaa gcccaagaaa cgcaacgaga cactggtctt
      781 cagtgagaac gcagtggtgg ctctgcgaga ccgccggctc tgtctcatgt ggcgggtggg
      841 caacctgcgc cgaagtcacc tggtggaggc gcacgtgcgg gcccagctgc tgcagccccg
      901 tgtgacccca gagggcgagt acatcccact ggaccaccag gatgtggatg ttggttttga
      961 cggaggcacc gatcgcatct tcctcgtatc ccccattacc attgtgcatg agattgactc
     1021 tgccagtcca ctgtatgagc tggggcgggc cgagctggcc cgggctgact tcgagctggt
     1081 ggtcattctt gaaggtatgg ttgaggccac agccatgact acacaatgcc gctcatctta
     1141 cctcccaggt gagctgctct ggggacatcg ctttgagcca gtcctcttcc agcgtggctc
     1201 ccagtatgag gttgactatc gacacttcca ccgaacgtat gaggtcccgg ggacgccagt
     1261 ctgcagtgcc aaggagctgg atgagcgggc agagcaggct tctcacagcc ctaagtcaag
     1321 ttttcctggc tcccttgctg cattttgtta tgagaatgaa ctagcgctga gctgctgcca
     1381 ggaggaagat gaagaagagg acactaagga ggggacttca gcagagaccc cagatagggc
     1441 tgccagcccc caagctctta caccaaccct ggcactgacc ctgcctccat gacatagctg
     1501 aggcccactt ccccatgtga caccccttcc caaagatgac agggatggag agcttccggc
     1561 ctctgatggg agtgggacag gggtttctca ggaccagtgg cctgctgaga taaccattaa
     1621 ccatgagaat gtctaccaca gatatactac acctttactt ctctgctcca gtctcactcc
     1681 cgagaccccc ttatgagctg gattcccacg tcttaccaga gctgagggat cagatttctg
     1741 gaccatacaa gagacaaggt gtggaggctg gattttggtt ggacatcagt gagagcctca
     1801 gggaggaagg tgtcaattta tacagatcga ggaacagaga ttcaagcaat gatagaatac
     1861 tccaaggatt caggatcatc ataattgacc aaagatagaa cagtgactgg actgcatgtg
     1921 gagaaaaggc ccggtggctc caaagagccc aagagttgag attctcttga gtctgggttg
     1981 acactgggga ttctaaaaca tgttggctag aggagagtgg agctgctcta gaaaccacaa
     2041 agctatgttt ctagaataca cagaacattg gtaggtttct cagtttggaa ggactaaggt
     2101 tccagatgct ggaggactct ggagtattgg ctgtttaggg tccgactgag ggggtggttc
     2161 tggcttcacc acgatccaca gggtgaattt tgtttttgct tgaagtgcca ttcttagaac
     2221 atccaaagga atcaagattc tatggttcgg ggttggtcag agtccaggta ggattctaaa
     2281 tgatttgctg gctccacttt gcccatcagg gttgaggatc tctatgatcg tgggtagctt
     2341 tctgtggttc tgtaatgcca aaaggaatcg aaactccagg gaccagagct gtccttcccc
     2401 aaagcttaga agtctagtca ccttcagatg ggcagcctga taaactctag gaggcagaca
     2461 ctgttccccg tggagcttgc aagcaagagc ctagacaatc acggggctag ctaacggaaa
     2521 agggaaggaa gaggctgagg ctggcaagcc taaaatattc tggatgacga tacctagtga
     2581 tgtgtgtcta tttctcagat gctatgcgta cgtgtattat atatgatatg aatacagatc
     2641 tctatcttt
//
