LOCUS       NM_001106545            2745 bp    mRNA    linear   ROD 02-APR-2024
DEFINITION  Rattus norvegicus potassium voltage-gated channel modifier
            subfamily G member 1 (Kcng1), mRNA.
ACCESSION   NM_001106545 XM_001072764 XM_215951
VERSION     NM_001106545.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2745)
  AUTHORS   Mederos Y Schnitzler,M., Rinne,S., Skrobek,L., Renigunta,V.,
            Schlichthorl,G., Derst,C., Gudermann,T., Daut,J. and
            Preisig-Muller,R.
  TITLE     Mutation of histidine 105 in the T1 domain of the potassium channel
            Kv2.1 disrupts heteromerization with Kv6.3 and Kv6.4
  JOURNAL   J Biol Chem 284 (7), 4695-4704 (2009)
   PUBMED   19074135
REFERENCE   2  (bases 1 to 2745)
  AUTHORS   Salinas,M., Duprat,F., Heurteaux,C., Hugnot,J.P. and Lazdunski,M.
  TITLE     New modulatory alpha subunits for mammalian Shab K+ channels
  JOURNAL   J Biol Chem 272 (39), 24371-24379 (1997)
   PUBMED   9305895
REFERENCE   3  (bases 1 to 2745)
  AUTHORS   Post,M.A., Kirsch,G.E. and Brown,A.M.
  TITLE     Kv2.1 and electrically silent Kv6.1 potassium channel subunits
            combine and express a novel current
  JOURNAL   FEBS Lett 399 (1-2), 177-182 (1996)
   PUBMED   8980147
REFERENCE   4  (bases 1 to 2745)
  AUTHORS   Drewe,J.A., Verma,S., Frech,G. and Joho,R.H.
  TITLE     Distinct spatial and temporal expression patterns of K+ channel
            mRNAs from different subfamilies
  JOURNAL   J Neurosci 12 (2), 538-548 (1992)
   PUBMED   1740690
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474005.2.
            
            [WARNING] On May 10, 2024 this sequence was replaced by
            NM_001106545.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_215951.4, XM_001072764.1.
            
            ##Evidence-Data-START##
            CDS exon combination :: M81784.1 [ECO:0000331]
            RNAseq introns       :: partial sample support SAMEA5760383,
                                    SAMEA5760389 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2745
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q42"
     gene            1..2745
                     /gene="Kcng1"
                     /gene_synonym="Kh2; Kv6.1"
                     /note="potassium voltage-gated channel modifier subfamily
                     G member 1"
                     /db_xref="GeneID:296395"
                     /db_xref="RGD:631416"
     exon            1..395
                     /gene="Kcng1"
                     /gene_synonym="Kh2; Kv6.1"
                     /inference="alignment:Splign:2.1.0"
     exon            396..1194
                     /gene="Kcng1"
                     /gene_synonym="Kh2; Kv6.1"
                     /inference="alignment:Splign:2.1.0"
     CDS             421..1965
                     /gene="Kcng1"
                     /gene_synonym="Kh2; Kv6.1"
                     /note="potassium voltage-gated channel, subfamily G,
                     member 1; voltage-gated potassium channel subunit Kv6.1;
                     potassium channel, voltage-gated modifier subfamily G,
                     member 1"
                     /codon_start=1
                     /product="potassium voltage-gated channel subfamily G
                     member 1"
                     /protein_id="NP_001100015.1"
                     /db_xref="GeneID:296395"
                     /db_xref="RGD:631416"
                     /translation="MTLLPGDNSDYDYSALSCASDTSFHPAFFPQRQAIKGVFYRRAQ
                     RLGPQDDLHQSISLGDRRRQIIINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDIL
                     SVCDDYDVTCNEFFFDRNPGAFGTILTFLRAGKLRLLREMCALSFQEELLYWGIAEDH
                     LDGCCKRRYLQKIEEFAEMMEREDEEEALDSEDQESEGPSTSEGRLSRCMRRLRDMVE
                     KPHSGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEEQGQCSQMCHNVFIVESVCV
                     GWFSLEFLLRFIQAPSKFAFLRSPLTLIDLVAILPYYVTLLVDGAASSRRKPSTGNSY
                     LDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIALFA
                     PLLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGIL
                     LMAFPVTSIFHTFSRSYLELKQEQERVLIRRAQYLIKTKSQLSGMSQDSDILFGSASS
                     DTRDNN"
     exon            1195..2745
                     /gene="Kcng1"
                     /gene_synonym="Kh2; Kv6.1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcagggacc ggtagggccc aaggccacca aaggagaaga aggcacaggt acgggtggtg
       61 tggtccccta gaaggagatg ttcaggtgga gagcgcgtgt ggctcccgga ctgccacaca
      121 tgaagtgtcc tcgaacgtta tgcctgcagt gcccgtgaca gtttaacgaa ggatccacga
      181 cttggcgtga ggttggacct cctaaggaca ggagacaggt cgtgtggcat tctcacgata
      241 gagactcacg tggggaatga ggctcgggtc ctggcactcg ctgactagga tagaagagcg
      301 ccacgcacga acctcccacg acctcttcga aaactggaga ggtggctgcg cctcgggcca
      361 ggagccctgg gaggagcagc gctgggactt aaaagcccaa gagggatgtg aagcctcaaa
      421 atgaccctgt taccaggaga caactcggac tatgactata gtgctctaag ttgtgcctca
      481 gacacctcct tccacccagc cttcttccca cagcgccagg ccatcaaagg cgtcttctac
      541 cgcagggccc aacggttggg accgcaggac gacctgcacc agagcatctc acttggggac
      601 cgcaggcgac agatcatcat caacgtgggt gggatcaagt actcactacc ttggaccaca
      661 ctggatgagt tccccctgac gcggctgggc cagctcaagg cctgcaccaa cttcgacgac
      721 atcctgagcg tgtgtgatga ctatgacgta acctgcaacg agttcttctt cgaccgcaac
      781 ccgggggcct ttggcaccat cctcaccttc ctgcgggccg gcaagctgcg cctgcttcgg
      841 gagatgtgcg ccctgtcctt ccaggaggag ctgctgtact ggggcattgc ggaggaccac
      901 ctggacggct gctgcaagcg ccggtacctg cagaaaatcg aggagtttgc tgagatgatg
      961 gagagggagg atgaggagga ggcgctggac agcgaggatc aagagagtga gggtccatcc
     1021 accagcgagg gtcgcctgag ccgctgcatg aggaggctgc gtgacatggt ggagaagcca
     1081 cactcagggt tgcctggcaa ggtgtttgcc tgcctgtctg ttctgtttgt caccgtcacc
     1141 gctgtcaacc tgtctgtcag caccctgccc agcctgcgtg aggaggagga acagggccag
     1201 tgttcccaaa tgtgccacaa cgtcttcatc gtagagtcgg tgtgcgtggg ctggttctcc
     1261 cttgagttcc tgctgcggtt catccaggca cccagcaagt tcgccttcct gcggagcccg
     1321 ctgaccctca tcgatctggt ggccatcctg ccttactacg tcacactgct ggtggatggc
     1381 gctgcctcca gccgccgcaa gccaagcacc ggcaacagct acctggacaa ggttgggctg
     1441 gtgctgcgcg tgctgcgggc gctgcgcatc ctctacgtga tgcgcctggc ccggcattcc
     1501 ctggggctgc agaccctggg cctcaccgca cgccgctgca cgcgtgaatt cgggcttctg
     1561 ctgcttttcc tgtgtgtggc catcgctctc tttgccccac tgctctacgt catcgagaat
     1621 gagatggcag acagccccga attcaccagc atcccggcct gctactggtg ggctgtcatc
     1681 accatgacaa ccgtgggcta cggagacatg gtaccccgga gcacgccggg ccaggtggtg
     1741 gctctgagca gcatcctcag cggcatcctc ctcatggcct tcccggtcac ctccatcttc
     1801 catactttct cccgctctta cctggaactc aagcaggaac aagaacgggt gctgatccgc
     1861 cgggcccagt acctcatcaa aaccaagtct cagctcagtg gcatgtccca agacagtgac
     1921 atcttgtttg gaagtgcctc ttcagacact agggacaaca actgaggcga gaagatgccc
     1981 cctaccctgc ctgccagctg cggcttcatg cattcaccgc cactggagcc tggaaaagga
     2041 cttagcgctt tcaagtccag ccctggcctg ggactgacct gagcgagcca cggcacagaa
     2101 aggatatatg ccacatctcc aagagtcccc gccctccctc taagcccaga agtaacaggg
     2161 aagctagctc gagccagtgc ctcaccgacc tggcttctcg gttgcttctc ttccctaaga
     2221 agctgaccgg ccccatccca ccatgtaaag aacttgtgca gcaaagttct ttgcgcactg
     2281 agagactgcc tggcggaaaa cacatccggc agccacatgt gactttagtg tacatccacg
     2341 gaaggaagaa aaagcctgcc actgggactt tcaagaaagg atctgtgtct cttagtgaaa
     2401 ggaccacggt gatggggtcc cggggctggt gggacaatgg catgatggga gagaagcaaa
     2461 cagacagacc tttaaggagc ccaccaccgg acgctgttca ggctcctcct gctcctgcct
     2521 cctgggctcc tccttcatgc ttcttcctgc tcacactctc cacagccttt tatgcttgag
     2581 ggctctcttt tcagactcca ctcatcccag ccggggtggg ggacaccaac aagccggtca
     2641 tctctgctgt ttcaaaggtg aaatcgcttc attccatggt ttaaaattag tgagatttta
     2701 gcctactcca attattttag tatgaagaag aagaagaaga agaag
//
