LOCUS       NM_001105748            3712 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus potassium voltage-gated channel subfamily D
            member 1 (Kcnd1), mRNA.
ACCESSION   NM_001105748 XM_001063865 XM_217601
VERSION     NM_001105748.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3712)
  AUTHORS   Chiu CY and Tsaur ML.
  TITLE     K+ channel Kv4.1 is expressed in the nociceptors/secondary
            nociceptive neurons and participates in pain regulation
  JOURNAL   Eur J Pain 26 (10), 2238-2256 (2022)
   PUBMED   36097791
  REMARK    GeneRIF: K(+) channel Kv4.1 is expressed in the
            nociceptors/secondary nociceptive neurons and participates in pain
            regulation.
REFERENCE   2  (bases 1 to 3712)
  AUTHORS   Dabrowska J and Rainnie DG.
  TITLE     Expression and distribution of Kv4 potassium channel subunits and
            potassium channel interacting proteins in subpopulations of
            interneurons in the basolateral amygdala
  JOURNAL   Neuroscience 171 (3), 721-733 (2010)
   PUBMED   20849929
REFERENCE   3  (bases 1 to 3712)
  AUTHORS   Kim J, Wei DS and Hoffman DA.
  TITLE     Kv4 potassium channel subunits control action potential
            repolarization and frequency-dependent broadening in rat
            hippocampal CA1 pyramidal neurones
  JOURNAL   J Physiol 569 (Pt 1), 41-57 (2005)
   PUBMED   16141270
REFERENCE   4  (bases 1 to 3712)
  AUTHORS   Isbrandt D, Leicher T, Waldschutz R, Zhu X, Luhmann U, Michel U,
            Sauter K and Pongs O.
  TITLE     Gene structures and expression profiles of three human KCND (Kv4)
            potassium channels mediating A-type currents I(TO) and I(SA)
  JOURNAL   Genomics 64 (2), 144-154 (2000)
   PUBMED   10729221
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474078.1.
            
            On or before Oct 3, 2007 this sequence version replaced
            XM_217601.3, XM_001063865.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U89873.1, SRR8487227.274310.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132264,
                                           SAMD00132266 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3712
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /map="Xq12"
     gene            1..3712
                     /gene="Kcnd1"
                     /gene_synonym="Kv4.1"
                     /note="potassium voltage-gated channel subfamily D member
                     1"
                     /db_xref="GeneID:116695"
                     /db_xref="RGD:621364"
     CDS             1..1953
                     /gene="Kcnd1"
                     /gene_synonym="Kv4.1"
                     /note="potassium voltage-gated channel, Shal-related
                     subfamily, member 1; potassium voltage gated channel
                     Shal-related family member 1; potassium channel, voltage
                     gated Shal-related subfamily D, member 1"
                     /codon_start=1
                     /product="potassium voltage-gated channel subfamily D
                     member 1 precursor"
                     /protein_id="NP_001099218.1"
                     /db_xref="GeneID:116695"
                     /db_xref="RGD:621364"
                     /translation="MAAGVATWLPFARAAAVGWLPLAQQPLPPAPEVKASRGDEVLVV
                     NVSGRRFETWKNTLDRYPDTLLGSSEKEFFYDAESGEYFFDRDPDMFRHVLNFYRTGR
                     LHCPRQECIQAFDEELAFYGLVPELVGDCCLEEYRDRKKENAERLAEDEEAEQAGEGP
                     ALPAGSSLRQRLWRAFENPHTSTAALVFYYVTGFFIAVSVIANVVETIPCRGPARWPT
                     KEQPCGDRFPTAFFCMDTACVLIFTGEYLLRLFAAPSRCRFLRSVMSLIDVVAILPYY
                     IGLFVPKNDDVSGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLT
                     MAIIIFATVMFYAEKGTSKTNFTSIPAAFWYTIVTMTTLGYGDMVPSTIAGKIFGSIC
                     SLSGVLVIALPVPVIVSNFSRIYHQNQRADKRRAQQKVRLARIRLAKSGTTNAFLQYK
                     QNGGLEDSGSGEGQMLCVRSRSAFEQQHHHLLHCLEKTTCHEFTDELTFSEALGAVSL
                     GGRTSRSTSVSSQPMGPGSLFSSCCSRRGERRAIRLANSTASVSRGSMQELDTLAGLR
                     RSPAPQSRSSLNAKPHDSLDLNCESRDFVAAIISIPTPPANTPDESQPSSPGGGGSGG
                     MANTTLRNSSLATPCLLPETVKISSL"
     exon            1..1121
                     /gene="Kcnd1"
                     /gene_synonym="Kv4.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1122..1284
                     /gene="Kcnd1"
                     /gene_synonym="Kv4.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1285..1368
                     /gene="Kcnd1"
                     /gene_synonym="Kv4.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1369..1467
                     /gene="Kcnd1"
                     /gene_synonym="Kv4.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1468..1718
                     /gene="Kcnd1"
                     /gene_synonym="Kv4.1"
                     /inference="alignment:Splign:2.1.0"
     exon            1719..3712
                     /gene="Kcnd1"
                     /gene_synonym="Kv4.1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggcggcag gtgtggccac atggctacca tttgcaaggg ctgcagcagt gggctggctg
       61 cccttagccc agcagcccct acccccagca ccggaggtga aggcatcccg aggggatgag
      121 gttctggtgg tgaacgtgag tggtcggcgc tttgaaacct ggaagaacac gctggatcgc
      181 tacccagaca cattgctagg cagctcagag aaggaattct tctatgatgc tgaatctggc
      241 gagtacttct ttgatcgtga ccctgacatg ttccggcacg tgctgaactt ttatcgcaca
      301 ggccgactac actgccccag gcaggagtgc atccaggcct ttgatgagga gctagccttc
      361 tatggcttag tcccagagct tgttggtgac tgctgtcttg aagagtatag ggaccgcaag
      421 aaggagaatg cagagcgcct ggcagaagat gaggaggccg agcaggccgg ggaaggtcca
      481 gcccttccag caggcagctc cctgcgacag cgactctgga gggcctttga aaacccacac
      541 acaagcactg cagcactggt tttctactat gtgactggct tctttatagc tgtgtcagtc
      601 attgccaacg tagtggagac catcccatgc cgtggtcctg cacggtggcc cacaaaagag
      661 cagccgtgtg gtgaccgctt ccctacagcc tttttctgta tggacacggc ctgtgtgctc
      721 atattcaccg gggaatacct tctgcggctt tttgcagccc ccagccgttg ccgcttcctg
      781 cgtagtgtta tgagcctcat cgatgtggtg gccatcctgc cctactacat tgggcttttt
      841 gtgcccaaga acgatgacgt ctctggtgcc tttgtcaccc tacgtgtgtt tcgggtcttc
      901 cgaatcttca agttctccag gcactcccag ggcttgcgga ttctgggcta caccctcaag
      961 agctgtgctt ccgagctagg cttcctcctc ttttccctca ccatggctat catcatcttt
     1021 gccactgtca tgttctatgc tgagaagggc accagcaaga ccaacttcac aagcatccct
     1081 gctgccttct ggtataccat tgtcaccatg accacacttg ggtatggcga catggtgcct
     1141 agcaccatcg caggcaaaat ttttgggtcc atctgctcac ttagtggtgt cttggtcatt
     1201 gccttgcctg taccagtcat tgtgtctaac ttcagccgta tataccacca gaaccagcgt
     1261 gctgacaagc gccgagcaca gcagaaggta cgcctggcaa gaatccggtt ggcaaagagt
     1321 ggtaccacca acgccttctt gcagtataag caaaatgggg gccttgagga cagtggcagt
     1381 ggggagggac agatgctgtg cgttaggagc cgctctgctt tcgaacaaca gcatcaccat
     1441 ctgctgcatt gtttggagaa gactacgtgt catgagttca cagacgagct cactttcagt
     1501 gaggcccttg gagctgtctc actgggtggt cgcaccagcc gcagtacctc agtatcatcc
     1561 cagccaatgg ggcctgggag cctgttttca tcctgctgct ctagaagggg agagcgcaga
     1621 gccatccgcc ttgccaactc tactgcgtct gtcagccgtg gcagcatgca ggagctagac
     1681 acactagcgg gtcttcggag gagccctgcc cctcagagcc gctcaagcct caatgccaag
     1741 ccccatgaca gccttgacct gaactgtgag agccgggact tcgtggctgc catcatcagt
     1801 atccccaccc ctcctgccaa cacgccagat gagagtcaac cttcctcccc tggtggcggt
     1861 ggcagtggtg gcatggctaa caccaccctc aggaactcca gcttggctac tccgtgcctc
     1921 ctccctgaga ctgtcaagat ctcttccctg tgaggaatgg gcctgcccat tcagagggcc
     1981 ttctttattc ttgggaactc ctttccaaag ccatattttg gggaggcaaa gagggacaga
     2041 cccgggaact ccttatgccc ccagacaaga actatgcaat ggagtttcat agaatggccc
     2101 atctgatggg gaagtaggga acgaggaact tccctcagtt cagacagttt ttcttgtggg
     2161 agcttgaagc atgggactcc ataggtccct ggcctccttg ccccagcatg ctgggactgg
     2221 cctctctctc ctagctggcc tcttgcatgc ctcttccctt gggccctctg aggcaggtta
     2281 aagctttcta tagtctgaca tttgaggtct ggtctgacaa gagttgagag tttctcttct
     2341 ctttggttgt gttgcgcagg tttgggggtt cagggaagag aaccctcaac tctaatttag
     2401 cctctagggg gcaaggtttt gtccttctca ggcccagcat ttcccagatt tggaagcttg
     2461 gaatgcaacc ctgggctggc ttaatgggct gtggcctctg tagtgacctg ctaccctcaa
     2521 gctttgcctg agggggtcag gctgcttctc ccaacaaaga gatagcacaa acactaccct
     2581 cccctggcta gctgctggaa gtgacttcct gccacctgtc ttctgctggg cctccagcaa
     2641 actagcaata gcagctgctg tcataccaat gtgcaaagcc tcggaccaat tcgctgcagc
     2701 atatacatgt gctctgatca gatgggccac atctaactac tctcttctct gatgtgctcc
     2761 cttcttgggt tggtctgcag tctggacctg ctgagataag agactaacat ccagcaagag
     2821 ctggcgtggg ctggtttcat attcttgggc agaaatccag aaatagtgtg ggcagaggac
     2881 aaaattgttc ctgacccctg ggagagatag aagatatcgc ctccttctct gctgtaactc
     2941 cttttgctcg ctgtcttctc ctccctcttg ggtcacttgg atctatgctc tcagaccgaa
     3001 tctcacgtta tctcaggttc ccttgtctcc agctctgtcc ctctaaagct ggcagctgac
     3061 aaagatgaag ttttcatcag tcaataaaac ctaagaggag agatgtggac cgaacatcta
     3121 ccgactctgt ggattgactt tgagggctgg gttcggctga ggggttaaga acactgtggt
     3181 ctcactttct ttcaacagtg aaggggcact ggtgtgggta gatgggtggt agatgggtag
     3241 atgggtgctg tcttcttgaa gatgtggatc atagagaaat gaaagagggt gctttgaaga
     3301 gttggtctct gtaggcagtg aaacaggccg gatggtccta aaactgatgt accttaggta
     3361 atattctatt ccagatcctt tattcataga aggagaagcc aagatctaga gcaacatgga
     3421 gttactttga gggggaactt aagaccatgc ttcctgatag caaaaaccta taaatctaac
     3481 cctaatagaa tgattactga ttttggtaat aatccccctt cctcatggat agctcctcca
     3541 ttatattgtt ctattctgga taccagctac accaggctag tatgagactg agttgtgtag
     3601 agccctgtga agaccaatct tggattcaga ttgacatatt tcagttcttg gatgagagac
     3661 tcactctttg tgtcaagttg ttaatttgaa gtagagatag taatttcttc at
//
