LOCUS       NM_031652               2106 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus potassium voltage-gated channel subfamily A
            regulatory beta subunit 3 (Kcnab3), mRNA.
ACCESSION   NM_031652
VERSION     NM_031652.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2106)
  AUTHORS   Ha,T.S., Heo,M.S. and Park,C.S.
  TITLE     Functional effects of auxiliary beta4-subunit on rat
            large-conductance Ca(2+)-activated K(+) channel
  JOURNAL   Biophys J 86 (5), 2871-2882 (2004)
   PUBMED   15111404
  REMARK    GeneRIF: the auxiliary beta4-subunit has a function in rat
            large-conductance Ca(2+)-activated K(+) channel
REFERENCE   2  (bases 1 to 2106)
  AUTHORS   Heinemann,S.H., Rettig,J., Wunder,F. and Pongs,O.
  TITLE     Molecular and functional characterization of a rat brain Kv beta 3
            potassium channel subunit
  JOURNAL   FEBS Lett 377 (3), 383-389 (1995)
   PUBMED   8549760
REFERENCE   3  (bases 1 to 2106)
  AUTHORS   Rettig,J., Heinemann,S.H., Wunder,F., Lorra,C., Parcej,D.N.,
            Dolly,J.O. and Pongs,O.
  TITLE     Inactivation properties of voltage-gated K+ channels altered by
            presence of beta-subunit
  JOURNAL   Nature 369 (6478), 289-294 (1994)
   PUBMED   8183366
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Mar 2, 2021 this sequence version replaced NM_031652.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X76723.1, SRR26643298.61390.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMEA5760393
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-621               JAXUCZ010000010.1  54546638-54547258
            622-665             JAXUCZ010000010.1  54548493-54548536
            666-703             JAXUCZ010000010.1  54548625-54548662
            704-783             JAXUCZ010000010.1  54548872-54548951
            784-828             JAXUCZ010000010.1  54550234-54550278
            829-873             JAXUCZ010000010.1  54550367-54550411
            874-917             JAXUCZ010000010.1  54550567-54550610
            918-1004            JAXUCZ010000010.1  54550866-54550952
            1005-1090           JAXUCZ010000010.1  54551195-54551280
            1091-1211           JAXUCZ010000010.1  54551387-54551507
            1212-1306           JAXUCZ010000010.1  54551588-54551682
            1307-1427           JAXUCZ010000010.1  54551786-54551906
            1428-1516           JAXUCZ010000010.1  54552068-54552156
            1517-2106           JAXUCZ010000010.1  54552393-54552982
FEATURES             Location/Qualifiers
     source          1..2106
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q24"
     gene            1..2106
                     /gene="Kcnab3"
                     /note="potassium voltage-gated channel subfamily A
                     regulatory beta subunit 3"
                     /db_xref="GeneID:58981"
                     /db_xref="RGD:61830"
     exon            1..621
                     /gene="Kcnab3"
                     /inference="alignment:Splign:2.1.0"
     CDS             380..1594
                     /gene="Kcnab3"
                     /note="potassium voltage gated channel, shaker related
                     subfamily, beta member 3; potassium channel, voltage gated
                     subfamily A regulatory beta subunit 3; RCK beta3;
                     kv-beta-3; K(+) channel subunit beta-3; potassium channel,
                     voltage gated shaker-related subfamily A regulatory beta
                     subunit 3"
                     /codon_start=1
                     /product="voltage-gated potassium channel subunit beta-3"
                     /protein_id="NP_113840.1"
                     /db_xref="GeneID:58981"
                     /db_xref="RGD:61830"
                     /translation="MQVSIACTEQNLRSRSSEDRLCGPRPGPGGGNGGPVGGGHGNPP
                     GGGGLGSKSRTAVVPRPPAPAGALRESTGRGTGMKYRNLGKSGLRVSCLGLGTWVTFG
                     SQISDETAEDLLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSKGWRRSSYVITTKI
                     FWGGQAETERGLSRKHIIEGLQGSLDRLQLEYVDIVFANRSDPSSPMEEIVRAMTYVI
                     NQGLALYWGTSRWSAAEIMEAYSMARQFNLIPPVCEQAENHFFQREKVEMQLPELYHK
                     IGVGSVTWSPLACSLITSKYDGQVPDACKATVKGYQWLKEKVQSEDGKKQQARVTDLL
                     PIAHQLGCTVAQLAIAWCLRSEGVSSVLLGVSSAEQLMEHLGSLQVLGQLTPQTVMEI
                     DALLGNKSHSKK"
     exon            622..665
                     /gene="Kcnab3"
                     /inference="alignment:Splign:2.1.0"
     exon            666..703
                     /gene="Kcnab3"
                     /inference="alignment:Splign:2.1.0"
     exon            704..783
                     /gene="Kcnab3"
                     /inference="alignment:Splign:2.1.0"
     exon            784..828
                     /gene="Kcnab3"
                     /inference="alignment:Splign:2.1.0"
     exon            829..873
                     /gene="Kcnab3"
                     /inference="alignment:Splign:2.1.0"
     exon            874..917
                     /gene="Kcnab3"
                     /inference="alignment:Splign:2.1.0"
     exon            918..1004
                     /gene="Kcnab3"
                     /inference="alignment:Splign:2.1.0"
     exon            1005..1090
                     /gene="Kcnab3"
                     /inference="alignment:Splign:2.1.0"
     exon            1091..1211
                     /gene="Kcnab3"
                     /inference="alignment:Splign:2.1.0"
     exon            1212..1306
                     /gene="Kcnab3"
                     /inference="alignment:Splign:2.1.0"
     exon            1307..1427
                     /gene="Kcnab3"
                     /inference="alignment:Splign:2.1.0"
     exon            1428..1516
                     /gene="Kcnab3"
                     /inference="alignment:Splign:2.1.0"
     exon            1517..2106
                     /gene="Kcnab3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggtcccgc agcggttcca gctgaagtgg caccggtctt ttgctacccc ttgttcctgg
       61 gtagctatcc tggaagaccg tcctcgactt ttctttatcc ttacccgttt atcctcctac
      121 tcccttcatc acagccccca gcacctgaat atccaccact ccgggcgacc ccacggtttt
      181 cctttcccgc cgcaaaaccc gcgacctcca acagcccgcc cccgcgggcc cgatcccgtt
      241 tggcggctct agctgcagcc tcctctgcct tcccactctc ccagggatcg ctctactacc
      301 ccaccggtgt ctgccctcaa cttccccgct ccctcctccc gctccctcgg agccccctcc
      361 cccgccctgg ccatccggca tgcaggtgtc tatcgcgtgt accgagcaga accttcgcag
      421 ccggagcagt gaggaccgtc tctgtggacc ccggccgggt cctggaggcg gtaatggagg
      481 gccagtgggc ggagggcatg ggaaccctcc ggggggtgga ggattgggct ccaagtcacg
      541 gactgcagtg gtcccccgac ccccagcacc tgctggggcc cttcgagaga gcaccggccg
      601 aggcactggc atgaaataca ggaacctagg aaagtctgga ctccgggtgt cctgtcttgg
      661 cctcggaacc tgggtcacat ttggctctca gatctcagat gagacagcag aagatctcct
      721 gacagtagcc tatgagcacg gtgtaaacct gtttgacacc gctgaagtgt acgcagcagg
      781 aaaggctgaa agaaccctag gcaacatcct caagagcaaa ggttggagga gatcaagcta
      841 tgttatcacc accaagattt tttggggagg acaggcagaa actgagcgag gcttgagtcg
      901 caaacacatc attgaaggct tgcaaggatc cctggaccgc ctccaactgg aatacgttga
      961 catagtattt gccaatcgtt cagaccccag cagtcctatg gaggagattg taagagccat
     1021 gacctatgtc atcaaccagg gcctggccct atactggggg acatccaggt ggagtgctgc
     1081 agaaatcatg gaggcctact ccatggccag acagttcaat ctgatccctc ctgtgtgtga
     1141 acaagcggag aaccacttct ttcagaggga gaaggtggag atgcagctgc ctgagctcta
     1201 ccacaaaatt ggtgttggct cagtcacttg gtctcccctg gcgtgcagcc tcattactag
     1261 caagtacgat gggcaagttc cagatgcttg caaggccact gtcaagggct accagtggct
     1321 caaagaaaaa gtgcaaagtg aagatggcaa gaagcaacaa gccagagtga cggaccttct
     1381 ccccatcgct caccagctag gctgcaccgt ggcccaactt gctatagcct ggtgtctccg
     1441 aagcgaaggt gtcagctcag ttttactggg ggtgtccagt gcagagcagc tgatggaaca
     1501 tctgggctcc ctacaggtgc tgggtcagct gacgccgcaa acggtgatgg aaatagatgc
     1561 gctcttgggg aacaaatcgc attccaagaa atagtccgtt gtgggcgcgg gaacccaacg
     1621 cggagtgatt gcaccctttg gaaaaccact ttcctgcatc ctgcaatcag ctctggatcc
     1681 ccaccaacca aaccctgctc ccacgcagcg ccgcggcaga atcagggtag ccccgcccac
     1741 caacgagtcc cggcttcgag tagcgattcg catgaacaaa gccatatcct ttcaccgtgg
     1801 ggcaccgggc aggagaggga aagtagatct cccgcccacc ctctacgccc ctgctgtttc
     1861 ctagggctag gccttctcgc taatccaggg catgagcctt ctctccgcca tttggtctcg
     1921 caccgctctg ctcatttctt ccccctgttg ctgaaaccta gaaaacatgg agcagctaaa
     1981 agaaacattg aaagcatctc aaaaatgggc cttgaaatgt catcaagggg gcaagaacct
     2041 acactgggaa gggggctttg tagtatttgt ccaatagaag ccaggctggc cctggcagaa
     2101 agtaaa
//
