LOCUS       NM_001109250            3510 bp    mRNA    linear   ROD 05-DEC-2024
DEFINITION  Rattus norvegicus kelch repeat and BTB domain containing 8
            (Kbtbd8), mRNA.
ACCESSION   NM_001109250 XM_001076969 XM_575612
VERSION     NM_001109250.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3510)
  AUTHORS   Werner,A., Iwasaki,S., McGourty,C.A., Medina-Ruiz,S.,
            Teerikorpi,N., Fedrigo,I., Ingolia,N.T. and Rape,M.
  TITLE     Cell-fate determination by ubiquitin-dependent regulation of
            translation
  JOURNAL   Nature 525 (7570), 523-527 (2015)
   PUBMED   26399832
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC160902.1 and CR467699.1.
            
            On Apr 25, 2009 this sequence version replaced NM_001109250.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC160902.1, SRR8487230.13242.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132268, SAMD00132291
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3502              BC160902.1         1-3502
            3503-3510           CR467699.1         1-8                 c
FEATURES             Location/Qualifiers
     source          1..3510
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q34"
     gene            1..3510
                     /gene="Kbtbd8"
                     /gene_synonym="RGD1563166"
                     /note="kelch repeat and BTB domain containing 8"
                     /db_xref="GeneID:500262"
                     /db_xref="RGD:1563166"
     exon            1..55
                     /gene="Kbtbd8"
                     /gene_synonym="RGD1563166"
                     /inference="alignment:Splign:2.1.0"
     CDS             40..1845
                     /gene="Kbtbd8"
                     /gene_synonym="RGD1563166"
                     /note="kelch repeat and BTB (POZ) domain containing 8"
                     /codon_start=1
                     /product="kelch repeat and BTB domain-containing protein
                     8"
                     /protein_id="NP_001102720.2"
                     /db_xref="GeneID:500262"
                     /db_xref="RGD:1563166"
                     /translation="MAASADLSKSSPTPNGIPSSDTANDTMDPFHACSILKQLKTMYD
                     EGQLTDIVVEVDHGKTFSCHRNVLAAISPYFRSMFTSGLTESTQKEVRIIGVEAESMG
                     LVLNYAYTSRVILTEANVQALFTTASIFQIPSIQDQCAKYMISHLDPQNSIGVFIFAD
                     HYGHQELGDRSKEYIRKKFLCVTKEQEFLQLTKDQLISILDSDDLNVDREEHVYESII
                     RWFEHEQNEREVHLPEIFAKCIRFPLMEDAFIEKIPPRFAQAIVKSCGEKGPSNTNGC
                     TQRLGMTASEMIICFDAAHKHSGKKQTVPCLDIVTGRVFKLCKPPNDLREVGILVSPD
                     NDIYIAGGYRPSSSEVSIDHKAENDFWMYDHSTNRWLSKPSLLRARIGCKLVYCCGKM
                     YAIGGRVYEGDGRNSLKSVECYDSRENCWMTVCAMPVAMEFHNAVEHKEKIYVLQGEF
                     FLFYEPQKDYWGFLTPMTVPRIQGLAAVYKDSIYYIAGTCGNHQRVFTVEAYDIELNK
                     WTRKKDFPCDQSINPYLKLVLFQNKLHLFVRATQVTVEEHIFRTSRKNSLYQYDDIAD
                     QWMKVYETPDRLWDLGRHFECAVAKLYPQCLQKVL"
     exon            56..266
                     /gene="Kbtbd8"
                     /gene_synonym="RGD1563166"
                     /inference="alignment:Splign:2.1.0"
     exon            267..1381
                     /gene="Kbtbd8"
                     /gene_synonym="RGD1563166"
                     /inference="alignment:Splign:2.1.0"
     exon            1382..3506
                     /gene="Kbtbd8"
                     /gene_synonym="RGD1563166"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttcctcttta aataaccgga gccggggccc cttggagaaa tggccgcgtc ggcagattta
       61 agtaagtctt ccccaacacc gaatgggatt ccatcttcag acacagccaa cgataccatg
      121 gaccctttcc atgcttgcag tattcttaag caactcaaaa caatgtacga tgaaggacag
      181 ttgacagaca ttgtagtgga agtggatcac gggaaaacat tttcctgtca tagaaacgtt
      241 cttgctgcaa tcagcccgta cttcagatcc atgttcacta gcggccttac agaaagtact
      301 cagaaagaag tgcggatcat cggtgttgaa gctgaatcga tgggtttggt attgaattat
      361 gcgtatacct ctagggttat tctgacagag gccaatgtgc aagccctgtt cactacagcc
      421 agcatcttcc agattccttc catccaagac cagtgcgcca agtatatgat tagtcatctg
      481 gatccacaga attctattgg agtctttatc tttgctgatc attatggtca tcaggaactt
      541 ggagatcgat cgaaagaata catccgtaaa aagttcctgt gtgtcaccaa agaacaagag
      601 tttctccagc tgacaaaaga ccaactcata agcatactag atagtgatga cttaaatgta
      661 gaccgggaag aacatgttta tgaaagcatt ataaggtggt ttgaacatga gcagaatgaa
      721 agagaagtac accttccaga aatttttgcc aaatgtatac gttttcctct aatggaagat
      781 gcatttattg agaaaattcc tcctcggttt gcgcaggcca tagtcaaaag ctgtggagaa
      841 aagggaccat ccaacaccaa tggctgtact cagaggcttg gaatgacagc ttccgaaatg
      901 atcatatgtt ttgatgctgc acacaaacac tcaggaaaga agcaaacagt gccttgtcta
      961 gatatagtca caggaagagt gtttaaacta tgcaaaccac caaatgacct aagagaagtt
     1021 gggattcttg tatcaccaga taatgacata tacattgcag gagggtacag gccaagcagc
     1081 agtgaggtgt ccattgatca caaagcagaa aatgattttt ggatgtatga ccattccacc
     1141 aaccgatggc tttccaagcc atccttgctt cgggccagaa taggctgcaa actagtatat
     1201 tgctgtggta aaatgtatgc aattggaggg cgtgtttacg aaggcgatgg acgaaactca
     1261 ctgaagtctg tggaatgcta tgatagcaga gagaattgct ggatgactgt ttgcgccatg
     1321 ccagttgcaa tggagtttca taatgctgtg gagcacaaag aaaaaatcta cgttttacag
     1381 ggagaatttt tcctcttcta tgagcctcaa aaagactact ggggattttt aacccccatg
     1441 actgtgccta gaatccaggg cttagcggct gtgtataaag actccatcta ctacatagct
     1501 ggaacctgtg gaaatcatca gcgtgtgttt actgttgaag cctatgatat tgagctaaat
     1561 aaatggactc gaaaaaagga ctttccttgt gatcagtcta taaatccata ccttaagctg
     1621 gtacttttcc agaataaact tcatttattt gtgcgagcta ctcaagtgac tgttgaagaa
     1681 catatcttca gaaccagcag gaaaaattct ctttaccagt atgatgacat cgctgaccag
     1741 tggatgaaag tgtatgagac cccagatcgg ctgtgggacc ttggccgcca ttttgagtgt
     1801 gcagtggcta aactctatcc tcagtgtctt cagaaagttc tttaataaat agcaggccaa
     1861 agcacgtcac tggcatctct catactaagg aagcttgttt aggaaatgct gtcaacattg
     1921 aagaaagcta acagttttgt attcagaaat gggtgctcgt aaagatagtg gtgttgggag
     1981 ggatttgctt ttaccttcat gattttttca ttttagtcag gaaaggtaac aaagtgcaat
     2041 tatcagcatt tttccacccc tggcataaaa gtatcatcct agaattttgt gataaatagt
     2101 tgctgagaaa ccaggtgaat tcaagacaac tatgcactct tgaaaagcag agtattcctg
     2161 ggtagagaaa tccaaactgg ttaacgtgac tttttatttt aaatacgggt aacaatatga
     2221 ggcaatatca tttatttagc tgtgatctct ctaacacaga gaagcactaa cttagatcct
     2281 cagtcttact atttatatct atttacatat atatttttgt gtgctgtttt caagtgtacg
     2341 agatttaaat gtgctctgtc agactgaagg aaaactcagt tttcagaacg aacttcagat
     2401 tgtttcatat ttctcatgta acttttaagt taagctacaa ggttaaagtg gcagtttttc
     2461 tgtccataac tttttcaagt gctaacactg tctcattaaa atcccagata gggctcagat
     2521 ttgcaggtga ctggtgctcg tataagttaa ttcacgtgtc gttagattga tttaaatggt
     2581 ttatgagtca atgtttctct ttcggattag catgctagtt ccatggttgt ggcactttac
     2641 cttgtgactc cacaaggtct gctatttgtg tgataggatc tggccgatgg ccattagtct
     2701 aactggattc agttttacaa ttccaagttt gcactaacac gggctgtttt gttgcccaaa
     2761 ctttttccat cctctacctt tccagtcatt gctagtatcg tgaaagttaa ctaatactgt
     2821 gaagttttaa cacctactta caaaattctg ttttccagaa acaagagtct tggagtggtc
     2881 taataattca gtggcttcta aggttcctat gacagttaca acctctattt tttgcactca
     2941 acagtgatga atatttgtat gttgagacac ttgtatctga aggtgatgta gaaggaggga
     3001 tgagttgaat gaacagagtc ataggtttct gtactctagg tactaaggcg ctgttcatat
     3061 tgaactgata agtgtctcaa aattagttag gaatattaac attaactcct tttttaccta
     3121 aggcaggcat ttaggttgac aacatactca ttactattcc tataactgat aaagaatatt
     3181 acacataagg cagagcctgt cctcagaaca attttaaaga gaatcagttt gatttctcct
     3241 gaagaaaatt ggcatggttt atattgggaa taaagtctta cacgaagcgt gcggtgatag
     3301 atactgtgaa cgaatggaaa gcatagcctc ttgcatcaca tacctccttt tccagaaact
     3361 gtagactgct ttacagcggc cctgcaagcg gagagctctc tgaagcagtt caagtggaca
     3421 gcattcgcag aatgactgtg tatgtgtggc ttctcctaat ctctttgtaa actttgtcaa
     3481 ccaatatatt ttttttaacc tctctaaaaa
//
