LOCUS       NM_001107861            3434 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus kelch repeat and BTB domain containing 2
            (Kbtbd2), mRNA.
ACCESSION   NM_001107861 XM_001061645 XM_231798
VERSION     NM_001107861.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3434)
  AUTHORS   Zhang Z, Turer E, Li X, Zhan X, Choi M, Tang M, Press A, Smith SR,
            Divoux A, Moresco EM and Beutler B.
  TITLE     Insulin resistance and diabetes caused by genetic or diet-induced
            KBTBD2 deficiency in mice
  JOURNAL   Proc Natl Acad Sci U S A 113 (42), E6418-E6426 (2016)
   PUBMED   27708159
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474011.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001061645.1, XM_231798.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760434,
                              SAMN12840107 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3434
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q24"
     gene            1..3434
                     /gene="Kbtbd2"
                     /note="kelch repeat and BTB domain containing 2"
                     /db_xref="GeneID:312372"
                     /db_xref="RGD:1310317"
     exon            1..71
                     /gene="Kbtbd2"
                     /inference="alignment:Splign:2.1.0"
     exon            72..557
                     /gene="Kbtbd2"
                     /inference="alignment:Splign:2.1.0"
     CDS             388..2259
                     /gene="Kbtbd2"
                     /note="kelch repeat and BTB (POZ) domain containing 2"
                     /codon_start=1
                     /product="kelch repeat and BTB domain-containing protein
                     2"
                     /protein_id="NP_001101331.1"
                     /db_xref="GeneID:312372"
                     /db_xref="RGD:1310317"
                     /translation="MSTQEERQINTEYAVSLLEQLKLFYEQQLFTDIVLIVEGTEFPC
                     HKMVLATCSSYFRAMFMSGLSESKQTHVHLRNVDAAALQMIITYAYTGNLAINDSTVE
                     QLYETACFLQVEDVLQRCREYLIKKINAENCVRLLSFADLFSCEELKQSAKRMVEHKF
                     TAVYRQEAFMQLSHDLLIDILSSDNLNVEKEETVREAAMLWLEYNTESRSQYLSSVLS
                     QIRIDALSEVTQRAWFQGLPPNDKSVVVQGLYKSMPKFFKPRLGMTKEEMMIFIEASS
                     ENPCSLYSSVCYSPQAEKVYKLCSPPADLHKVGTVVTPDNDIYIAGGQVPLKNTKTNH
                     SKTSKLQTAFRTVNCFYWFDAQQNTWFPKTPMLFVRVKPSLVCCEGYIYAIGGDSVGG
                     ELNRRTVERYDTEKDEWTMVSPLPCAWQWSAAVVVHDCIYVMTLNLMYCYFPRSDSWV
                     EMAMRQTSRSFASAAAFGDKIFYIGGLHIATNSGIRLPSGTVDGSSVTVEIYDVNKNE
                     WKMAANIPAKRYSDPCVRAVVISNSLCVFMRETHLNERAKYVTYQYDLELDRWSLRQH
                     ISERVLWDLGRDFRCTVGKLYPSCLEESPWKPPTYLFSPDGTEEFELDGEMVALPPV"
     exon            558..723
                     /gene="Kbtbd2"
                     /inference="alignment:Splign:2.1.0"
     exon            724..3434
                     /gene="Kbtbd2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccgctgtgc gtgcggccgc gtgagtgcag cccggcggag cggcgcggtg agctgggcgg
       61 ccggggccga gttctgcaga aaacctactg aacataaaat gttgcaacaa aatctacctc
      121 ctgtactttt cccctttatt catgagcttc acagttgcaa atttgagcag gatgtttgga
      181 aaatctgttg aagaactgta gcgcaggatg acctagcaaa gattgtgagc ctgtaacaag
      241 atactcatag tggctgtgtc agctctgttc tgaatgctgc agataacagc aagtgaactc
      301 cctcctctac ttctcaagta ttcatttgac cttccatcaa gaaggacttt tctaatctgt
      361 tcttgaagat attaatggaa tacaatcatg tccactcaag aggaaaggca gatcaatacg
      421 gagtatgctg tgtccttgtt ggaacagttg aaactgtttt atgaacagca gttatttact
      481 gacatagtgt taattgttga gggcaccgaa ttcccttgtc ataagatggt tcttgcaaca
      541 tgtagctcct atttcagggc catgttcatg agtggactaa gtgaaagcaa gcagacacac
      601 gtgcacctga ggaatgtgga tgctgctgcc ttgcagatga taataactta cgcatacaca
      661 gggaacttgg cgataaacga cagcactgta gagcagctct atgaaaccgc ttgtttccta
      721 caggtagaag atgtgctaca gcgttgccga gaatatttaa ttaaaaaaat taatgcagag
      781 aactgtgtac ggctgttgag ttttgctgac ctcttcagtt gtgaagaatt aaagcagagt
      841 gctaaaagga tggtggagca caagttcacg gctgtgtacc gccaggaagc cttcatgcag
      901 ctgtcccacg acctcctcat agacatcctc agcagtgaca acttaaatgt agaaaaggaa
      961 gaaactgtgc gagaagctgc catgctgtgg ctagagtaca acacagagtc acgatcccag
     1021 tatttgtctt cggttcttag ccagatcaga attgatgcac tctctgaagt cacacaaaga
     1081 gcttggttcc aaggtctccc acccaacgat aagtctgttg tggttcaagg tctttataaa
     1141 tccatgccca agttcttcaa acccagactt gggatgacta aggaggagat gatgattttc
     1201 attgaagcat catcagaaaa cccttgtagt ctgtactctt ctgtctgtta cagcccccag
     1261 gcagaaaaag tttacaagtt atgcagccca ccagctgatt tgcataaagt tgggactgtc
     1321 gtaacccctg ataatgatat ttacatagca gggggccaag tgcccctgaa aaacacaaaa
     1381 acaaatcaca gtaaaacaag taaactgcag acagcctttc gaactgtgaa ttgcttttac
     1441 tggtttgatg cacaacaaaa tacctggttt ccaaagacac cgatgctttt tgtccgggtg
     1501 aagccatctt tggtttgctg tgaaggctat atctatgcaa tcggaggaga cagtgttggt
     1561 ggagaactaa atcggaggac tgtagaaagg tatgacactg agaaggatga gtggacaatg
     1621 gtgagcccct tgccttgcgc ttggcagtgg agtgcagcag ttgtggttca cgactgcatc
     1681 tatgtgatga cattaaacct catgtactgt tactttccaa ggtctgactc atgggtagaa
     1741 atggccatga ggcagaccag caggtctttt gcttcggccg cagcttttgg tgataaaatt
     1801 ttctatattg gagggttgca tattgctacc aattctggta taagactccc ctctggcact
     1861 gtagatgggt cttcagtaac tgtggaaatt tatgatgtga ataaaaatga gtggaaaatg
     1921 gcagccaaca tccctgctaa aaggtattct gatccctgtg ttagagctgt tgtgatctca
     1981 aattctcttt gtgtttttat gcgagaaacc catttaaatg aacgagctaa atatgtcacc
     2041 taccagtatg atttggaact tgaccggtgg tctctgcggc agcatatatc tgaacgtgta
     2101 ttgtgggacc tagggagaga ttttcgatgc actgtgggga aactttatcc atcctgtctt
     2161 gaagaatctc catggaagcc accaacttac cttttttcac cagatggaac agaggagttt
     2221 gaactggatg gagaaatggt tgcacttcca cctgtatagg ggagtcgagg gagtgcacat
     2281 gctgaacttg ggatatcctt tgctaaacca gaggatataa taggacagag tatgagtaca
     2341 taaaaatcta tctttgatac attttatttt tatgccctac ttaatatttg catcagtata
     2401 atatatatca gtgtgtcata cagaaagata tgcttctgta atatgaaata ggttatttga
     2461 taactgagaa acttaagtgt atcatgtgag cataagagtc tggatgatgt aacattgtta
     2521 gccctgtgta tgtacagtcc agaacttcac ttttaaaagt aatctcctgt tcccagtgtg
     2581 gaatttcaga attgtgccga gatcatttta gtgtatgtat tgaattcctg tacttccaaa
     2641 gtcctggaat ataggttttt ttgtttttgt ttttgttttt gttttttttt agtataattc
     2701 cgctgcactt aacactaata ttcatgttgg tatagaaatg tcttttaaat cctatactat
     2761 ggttgagcaa gatctgctat acgtctatgg tattacacag ggaaagctgt gactgcagga
     2821 tcagtctcac tattctacta ggtgcatgta ttcccttccc actgacttac actcgtctct
     2881 ctagaataca ggttgtccag tcagctggtc acttaccagg tgtggactta cattgctggg
     2941 cttgcaaatt gctagtccct cattgtgcgg gtctatgtgg agctttaatc agtaaatgtc
     3001 tccacttcct atattacatt aacgttggct catgcatata accacctgct gctgatgtag
     3061 ttatccatct taaaaagatt tagagtggat taaccaggtc attacatctt aatttaataa
     3121 tgagcattac tgtagagtga ttgtgtatag gtatctaata ggtgtgtttt tttttttaac
     3181 ctgatgtgtg tatgtttggg gggctaggat tagaaaggtg aactgtgcag gaattgtctg
     3241 cactgtgcag aagagcagat ccgagtgctg ctctgccatt aatcccagga accactagca
     3301 gtagtggggc gccaccaatg taacatgagc acaggtgcct catgacaaac atggctggca
     3361 tgttcaactg cataatgctc tggcactgta ttttgaatga cattaattta ttaaataaat
     3421 tgtatataat caat
//
