LOCUS       NM_001415945            4861 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus kazrin, periplakin interacting protein (Kazn),
            transcript variant 1, mRNA.
ACCESSION   NM_001415945
VERSION     NM_001415945.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4861)
  AUTHORS   Florea,L., Di Francesco,V., Miller,J., Turner,R., Yao,A.,
            Harris,M., Walenz,B., Mobarry,C., Merkulov,G.V., Charlab,R.,
            Dew,I., Deng,Z., Istrail,S., Li,P. and Sutton,G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res 15 (1), 54-66 (2005)
   PUBMED   15632090
REFERENCE   2  (bases 1 to 4861)
  AUTHORS   Groot,K.R., Sevilla,L.M., Nishi,K., DiColandrea,T. and Watt,F.M.
  TITLE     Kazrin, a novel periplakin-interacting protein associated with
            desmosomes and the keratinocyte plasma membrane
  JOURNAL   J Cell Biol 166 (5), 653-659 (2004)
   PUBMED   15337775
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760386
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-416               JAXUCZ010000005.1  160061466-160061881 c
            417-608             JAXUCZ010000005.1  159778041-159778232 c
            609-745             JAXUCZ010000005.1  159728548-159728684 c
            746-916             JAXUCZ010000005.1  159723775-159723945 c
            917-1106            JAXUCZ010000005.1  159721448-159721637 c
            1107-1237           JAXUCZ010000005.1  159717693-159717823 c
            1238-1288           JAXUCZ010000005.1  159714439-159714489 c
            1289-1412           JAXUCZ010000005.1  159712729-159712852 c
            1413-1618           JAXUCZ010000005.1  159691645-159691850 c
            1619-1737           JAXUCZ010000005.1  159690672-159690790 c
            1738-1969           JAXUCZ010000005.1  159685099-159685330 c
            1970-2071           JAXUCZ010000005.1  159682689-159682790 c
            2072-2238           JAXUCZ010000005.1  159682010-159682176 c
            2239-2353           JAXUCZ010000005.1  159680157-159680271 c
            2354-4861           JAXUCZ010000005.1  159675803-159678310 c
FEATURES             Location/Qualifiers
     source          1..4861
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..4861
                     /gene="Kazn"
                     /gene_synonym="Kaz"
                     /note="kazrin, periplakin interacting protein"
                     /db_xref="GeneID:313672"
                     /db_xref="RGD:1359147"
     exon            1..416
                     /gene="Kazn"
                     /gene_synonym="Kaz"
                     /inference="alignment:Splign:2.1.0"
     CDS             176..2518
                     /gene="Kazn"
                     /gene_synonym="Kaz"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="kazrin isoform 1"
                     /protein_id="NP_001402874.1"
                     /db_xref="GeneID:313672"
                     /db_xref="RGD:1359147"
                     /translation="MMEDNKQLALRIDGAVQSASQEVTNLRAELTATNRRLAELSGGG
                     GGPGSGPGAATSASAAAVTVADSAVATMENHQHGAQVLLREEVVQLQEEVHLLRQMKE
                     MLAKDLEESQGGKCSEVLSATELRVQLVQKEQELARAREALQAMKADRKRLKGEKTDL
                     VSQMQQLYATLESREEQLRDFIRNYEQHRKESEDAVKALAKEKDLLEREKWELRRQAK
                     EATDHAAALRSQLDLKDNRMKELEAELAMAKQSLATLTKDVPKRHSLAMPGETVLNGN
                     QEWVVQADLPLTAAIRQSQQTLYHSHPPHPADRQAVRVSPCHSRQPSVISDASAAEGD
                     RSSTPSDINSPRHRTHSLCNGDSPGPVQKSLHNPIVQSLEDLEDQKRKKKKEKMGFGS
                     ISRVFARGKQRKSLDPGLFDDSDSQCSPTRHSLSLSEGEEQMDRLQHVELVRTTPMSH
                     WKAGTVQAWLEVVMAMPMYVKACAENVKSGKVLLSLSDEDLELGLGVCSSLHRRKLRL
                     AIEDYRDAEAGRSLSKAADLDHHWVAKAWLNDIGLSQYSQAFQNHLVDGRMLNSLMKR
                     DLEKHLNVSKKFHQVSILLGIELLYQVNFSREALQERRARCETQNTDPVVWTNQRVLK
                     WVRDIDLKEYADNLTNSGVHGAVLVLEPTFNAEAMATALGIPSGKHILRRHLAEEMST
                     VFHPANSTGIRESERFGTPPGRASSITRAGKEDGSSNSKYRTGRLPLGKIGRGFSSKE
                     PDYYDDYGSLENEDCGDDDLQGRPEQCRLEEYSSLEVTNV"
     exon            417..608
                     /gene="Kazn"
                     /gene_synonym="Kaz"
                     /inference="alignment:Splign:2.1.0"
     exon            609..745
                     /gene="Kazn"
                     /gene_synonym="Kaz"
                     /inference="alignment:Splign:2.1.0"
     exon            746..916
                     /gene="Kazn"
                     /gene_synonym="Kaz"
                     /inference="alignment:Splign:2.1.0"
     exon            917..1106
                     /gene="Kazn"
                     /gene_synonym="Kaz"
                     /inference="alignment:Splign:2.1.0"
     exon            1107..1237
                     /gene="Kazn"
                     /gene_synonym="Kaz"
                     /inference="alignment:Splign:2.1.0"
     exon            1238..1288
                     /gene="Kazn"
                     /gene_synonym="Kaz"
                     /inference="alignment:Splign:2.1.0"
     exon            1289..1412
                     /gene="Kazn"
                     /gene_synonym="Kaz"
                     /inference="alignment:Splign:2.1.0"
     exon            1413..1618
                     /gene="Kazn"
                     /gene_synonym="Kaz"
                     /inference="alignment:Splign:2.1.0"
     exon            1619..1737
                     /gene="Kazn"
                     /gene_synonym="Kaz"
                     /inference="alignment:Splign:2.1.0"
     exon            1738..1969
                     /gene="Kazn"
                     /gene_synonym="Kaz"
                     /inference="alignment:Splign:2.1.0"
     exon            1970..2071
                     /gene="Kazn"
                     /gene_synonym="Kaz"
                     /inference="alignment:Splign:2.1.0"
     exon            2072..2238
                     /gene="Kazn"
                     /gene_synonym="Kaz"
                     /inference="alignment:Splign:2.1.0"
     exon            2239..2353
                     /gene="Kazn"
                     /gene_synonym="Kaz"
                     /inference="alignment:Splign:2.1.0"
     exon            2354..4861
                     /gene="Kazn"
                     /gene_synonym="Kaz"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 attcctgcgc cggaggagcc ggcgcttgcc ggtgcctggg ggtcggggcg cggggaaacc
       61 cgggccgctg gggtgaccca acaggtagag ccggggccac ggccggccac gcgccccccg
      121 cgtgcatcat gcagctcttt gtcacctctc tcgcccccag gccaaaatcc tgagcatgat
      181 ggaagacaat aagcagctcg cgctccgcat cgatggggcg gtccagtcgg ccagccagga
      241 ggtgaccaac ctgcgagccg aactcacggc caccaaccgg agactggcgg aattgagcgg
      301 cggaggcggc ggccccggct cgggcccggg agctgcgacc agcgcctcgg cagcagcggt
      361 gacggtggct gactcggcgg tggcgaccat ggagaaccat cagcacggag ctcaagtgct
      421 cctgcgggag gaagtggtcc agcttcagga ggaagtccac cttctccgac agatgaagga
      481 aatgctggca aaggacctag aggagtcaca gggcggcaaa tgctccgagg tgctgtcggc
      541 cactgaactc cgggtgcagc tggtacagaa ggagcaggag ctggccagag ccagggaagc
      601 cttgcaagcc atgaaagctg accggaagcg cttaaagggc gagaagaccg acctggtgag
      661 ccagatgcag cagttgtacg ccacgctgga gagccgcgag gagcagttgc gagacttcat
      721 ccgcaactat gaacaacacc gcaaggagag tgaggatgct gtcaaagcgc tggccaagga
      781 gaaagacctg ctggagcgag agaagtggga gctccgacgg caggccaagg aggccacgga
      841 ccatgctgcg gccctgcgct cccagctgga cctcaaggac aaccgcatga aggagctgga
      901 ggccgagcta gccatggcca agcagtcctt agccacactg accaaggatg ttcccaagag
      961 gcattcactc gccatgcccg gcgagacggt gctcaatggc aaccaggaat gggtggtgca
     1021 ggctgacctc ccactgactg ccgccatccg gcagagccaa cagactctct accactccca
     1081 ccctccccac cctgcagacc gacaagcggt cagggtgagc ccctgccact caagacagcc
     1141 ttccgtcatc tctgatgctt ccgctgctga aggtgaccgg tcatctacac cgagcgacat
     1201 caactcccca agacaccgga cacactccct ctgcaacggc gacagtcccg gcccagttca
     1261 gaagagccta cacaacccta ttgtacagtc actagaggat cttgaagacc aaaaacggaa
     1321 aaagaagaaa gagaagatgg gatttggctc catctctcga gtcttcgcca gagggaaaca
     1381 acggaagtcc ctcgacccgg gcctctttga tgactccgac agccagtgca gccccacacg
     1441 ccacagcctc agcctgtctg agggagagga gcagatggac cgtctacagc acgtggagct
     1501 ggtgaggacc acgcccatgt cccactggaa ggctggcacg gtgcaagcct ggctggaggt
     1561 ggtgatggcc atgcccatgt acgtcaaggc ctgtgcggag aatgtcaaga gtgggaaggt
     1621 gctgctcagc ctgagcgacg aggacctgga gttgggcctt ggtgtgtgca gctccttgca
     1681 caggcgcaag ctccgactgg ccattgagga ctaccgagat gccgaggcgg gccgcagcct
     1741 gtccaaagcc gccgacctgg accatcactg ggtggccaag gcctggctga acgacattgg
     1801 cctgtcccag tattcccagg ccttccagaa ccacctggtc gatgggagga tgctgaactc
     1861 gctgatgaag agggacctgg agaagcatct gaacgtgtcc aagaagtttc accaagttag
     1921 catcttgcta gggatcgagc tgctgtacca agtgaacttc agcagggagg ccctccagga
     1981 gcgcagagcc cgctgtgaaa cacagaacac agaccctgtg gtctggacca accagcgggt
     2041 gctcaagtgg gtgcgagata tcgacctgaa ggagtatgcc gacaacctga ccaacagcgg
     2101 agtccacggt gctgtgctgg tcctggagcc cacgttcaat gctgaggcca tggccaccgc
     2161 cctgggcatc cccagcggga agcacatcct caggagacac ctggcagagg agatgagcac
     2221 cgtcttccat ccagccaact ccacaggcat ccgagagtct gagcgctttg ggacaccgcc
     2281 tggcagggcc tccagcatca ccagagctgg gaaagaggac ggtagcagta acagcaagta
     2341 cagaactggc cggctgcccc tggggaagat aggaagaggc ttcagcagca aagagcctga
     2401 ttactatgat gactatggct ctctggagaa cgaggactgc ggggacgatg acctccaagg
     2461 caggcccgag cagtgtcgtc tggaggaata cagcagcttg gaggtcacca atgtgtaaga
     2521 aagccatgtg cctcaactcc agaacaggga ggaggaggag gagcccagtg tcccagagcc
     2581 gtccatcccc actgtacagc atgacccgga gctgaggaca gacaggcgtc agaacagagt
     2641 tcccagagac ggtcacaatt tccagggggc accaaggaca gagaatgccc accttggtgt
     2701 cctgtatctc tgaggacaga tcatccggtc accacccagt gggtggcccg ggtgctgctg
     2761 gttctttaca ctgaaccttc aaggacagtc aaggagggtc agtcttgtgg acctggaaca
     2821 ccctgccggg aggagtagga aagccactca gccttggcag agccagggac actgagaacc
     2881 aattgcaaag ccaaccagca gctgccaggt gatggacgct gaccatcagc ccactgggca
     2941 gagaacttga actctgacct ccgcgttcac tcaggaagga tgcaaaatgg cctgggcatt
     3001 gcttccattt taagagcagc acatcatgag gtggacgtgt cgggagcagg aagggaatct
     3061 ctgcagggca gaggggcctg acagcagccg ccctagggga ttcagacatc ccctgtcacc
     3121 aggatgaatg tgatttccag agtgggttgg gggatagcta ccgagttctg tcccaaacag
     3181 ctattccaag tgtgggcata aaatgggaaa ctgcttgtca ttaacccgac caacccctct
     3241 ggtgatgtcc ctgtcagctg agacaggtaa ggtcgcccat gagctaacag aggtgcaaat
     3301 ctcacagaac aaggtcaccg ggttgtctga gtgggatctt tttagccaca gtcttgatct
     3361 gccagtgttt tgctgtgtgg cttcctccca gtgacctcac ctctctgtgc ctcagtgtct
     3421 tacctataat acttccggtt ccttccagag gagccgtgag cattaacatt cactaacatt
     3481 tgtcccaagc tttgagcctc tcaggaaaca gctggacggg atgggacgtg gggaggaatg
     3541 agcctagttc cacccacaac atttgcagac accgggccag ttcgatccat tttggatggg
     3601 agagataggt aagaggggaa cgcagaacgt ttaatattga gagttttgcc tgtgggccta
     3661 ctgggtgcag ggtccaagct gactgagcag agccttcctt gatgacaggg aggaattcag
     3721 ggcagctctg ctctgtgcca actctcctca gattcccaga gatgataggg gggttagggg
     3781 ataggcacag cctctgagcc accaaagtca gacttctgta gcggtgtaga gagcttttct
     3841 ttgtgggaag accacacaaa gccagtaaac ttgaaagtca cggcccccca tgttaaagac
     3901 atctctctaa gggtcccaca ggcatggtct ccctcacaac ctgagtccag gggcctcgga
     3961 gatggggaga aatctttctg tttgaggctc agcctccaaa ggacacctgg cagacaccag
     4021 gactcacagg gtcaacctct ggggtgtaac ccagcttggt tcaggctcta cattcctgag
     4081 tgtttaaaat atgcattccc tgcccctgga atcctgaagc aactgaaccc ttagttcaat
     4141 aaggagaggg gaggccctcg tctaattgaa gccagctgtc actgtcaaac caagtcccta
     4201 aagggctaca cagcttctgg agccaggaat atactgacag ccttcctgga aatgttgctg
     4261 gctttgtggg ctccttgcaa gggtaaggtc taggtaggga gagactccac actttcttcc
     4321 tacaggctgg gagtcaaata gcatcaggag gctctttccc tgtggactct gggcctccat
     4381 cttgtgcatg tctgtctgtc tccatcctca cccagtggtc acttttagca gattctctat
     4441 ttcgactcct taccacaggt tgccgggtga ctagagtcag aagtggagag aggggctctc
     4501 ccctaagcct ggcctgcaca gggcacttag aacagggaac cctgccaaag actgaggtca
     4561 tgaaggtagg tggggtcaca gatgtaaatt tgaacttcag gaccatgact aagagctcca
     4621 gcaggatcag gacagccctt tccaggaggc ccaggaccat ttcccgggtt gtgggggaaa
     4681 gtgtctccta agtgggtggc aacttctggg tctcacttta cagaagccag tgtgggtggt
     4741 gatgtctcct gccccgtgaa aggtctgtaa atgcagggca aatgaacagt gaactcagtg
     4801 tccggcacct tcccggaggg aattttaaca atgtaacaat aaatgcttga ccttgaggcg
     4861 a
//
