LOCUS       NM_001024746            2662 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus katanin regulatory subunit B1 (Katnb1), mRNA.
ACCESSION   NM_001024746 XM_006255078 XM_214635
VERSION     NM_001024746.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2662)
  AUTHORS   Cheung,K., Senese,S., Kuang,J., Bui,N., Ongpipattanakul,C.,
            Gholkar,A., Cohn,W., Capri,J., Whitelegge,J.P. and Torres,J.Z.
  TITLE     Proteomic Analysis of the Mammalian Katanin Family of
            Microtubule-severing Enzymes Defines Katanin p80 subunit B-like 1
            (KATNBL1) as a Regulator of Mammalian Katanin Microtubule-severing
  JOURNAL   Mol Cell Proteomics 15 (5), 1658-1669 (2016)
   PUBMED   26929214
REFERENCE   2  (bases 1 to 2662)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   3  (bases 1 to 2662)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   4  (bases 1 to 2662)
  AUTHORS   Sudo,H. and Maru,Y.
  TITLE     LAPSER1 is a putative cytokinetic tumor suppressor that shows the
            same centrosome and midbody subcellular localization pattern as p80
            katanin
  JOURNAL   FASEB J 21 (9), 2086-2100 (2007)
   PUBMED   17351128
REFERENCE   5  (bases 1 to 2662)
  AUTHORS   Toyo-Oka,K., Sasaki,S., Yano,Y., Mori,D., Kobayashi,T.,
            Toyoshima,Y.Y., Tokuoka,S.M., Ishii,S., Shimizu,T., Muramatsu,M.,
            Hiraiwa,N., Yoshiki,A., Wynshaw-Boris,A. and Hirotsune,S.
  TITLE     Recruitment of katanin p60 by phosphorylated NDEL1, an LIS1
            interacting protein, is essential for mitotic cell division and
            neuronal migration
  JOURNAL   Hum Mol Genet 14 (21), 3113-3128 (2005)
   PUBMED   16203747
REFERENCE   6  (bases 1 to 2662)
  AUTHORS   Yu,W., Solowska,J.M., Qiang,L., Karabay,A., Baird,D. and Baas,P.W.
  TITLE     Regulation of microtubule severing by katanin subunits during
            neuronal development
  JOURNAL   J Neurosci 25 (23), 5573-5583 (2005)
   PUBMED   15944385
  REMARK    GeneRIF: the ratio of P60 to P80 varies markedly in different
            tissues, at different phases of development, and regionally within
            the neuron. Suggested that the effects on neuronal morphology are
            dependent on the degree of microtubule severing and loss of polymer
REFERENCE   7  (bases 1 to 2662)
  AUTHORS   McNally,K.P., Bazirgan,O.A. and McNally,F.J.
  TITLE     Two domains of p80 katanin regulate microtubule severing and
            spindle pole targeting by p60 katanin
  JOURNAL   J Cell Sci 113 (Pt 9), 1623-1633 (2000)
   PUBMED   10751153
REFERENCE   8  (bases 1 to 2662)
  AUTHORS   Hartman,J.J., Mahr,J., McNally,K., Okawa,K., Iwamatsu,A.,
            Thomas,S., Cheesman,S., Heuser,J., Vale,R.D. and McNally,F.J.
  TITLE     Katanin, a microtubule-severing protein, is a novel AAA ATPase that
            targets to the centrosome using a WD40-containing subunit
  JOURNAL   Cell 93 (2), 277-287 (1998)
   PUBMED   9568719
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000019.1.
            
            On or before Sep 13, 2022 this sequence version replaced
            XM_006255078.3, NM_001024746.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360181.3152336.1,
                                           SRR22582416.901292.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-157               JAXUCZ010000019.1  9946582-9946738     c
            158-454             JAXUCZ010000019.1  9945042-9945338     c
            455-585             JAXUCZ010000019.1  9940880-9941010     c
            586-703             JAXUCZ010000019.1  9937993-9938110     c
            704-804             JAXUCZ010000019.1  9932684-9932784     c
            805-846             JAXUCZ010000019.1  9932358-9932399     c
            847-930             JAXUCZ010000019.1  9931763-9931846     c
            931-1046            JAXUCZ010000019.1  9931484-9931599     c
            1047-1118           JAXUCZ010000019.1  9931085-9931156     c
            1119-1269           JAXUCZ010000019.1  9930765-9930915     c
            1270-1460           JAXUCZ010000019.1  9930470-9930660     c
            1461-1591           JAXUCZ010000019.1  9930227-9930357     c
            1592-1642           JAXUCZ010000019.1  9929893-9929943     c
            1643-1710           JAXUCZ010000019.1  9929090-9929157     c
            1711-1830           JAXUCZ010000019.1  9928863-9928982     c
            1831-1980           JAXUCZ010000019.1  9928621-9928770     c
            1981-2057           JAXUCZ010000019.1  9928320-9928396     c
            2058-2132           JAXUCZ010000019.1  9928172-9928246     c
            2133-2249           JAXUCZ010000019.1  9927921-9928037     c
            2250-2662           JAXUCZ010000019.1  9927249-9927661     c
FEATURES             Location/Qualifiers
     source          1..2662
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19p13"
     gene            1..2662
                     /gene="Katnb1"
                     /note="katanin regulatory subunit B1"
                     /db_xref="GeneID:291852"
                     /db_xref="RGD:1311256"
     exon            1..157
                     /gene="Katnb1"
                     /inference="alignment:Splign:2.1.0"
     exon            158..454
                     /gene="Katnb1"
                     /inference="alignment:Splign:2.1.0"
     CDS             415..2382
                     /gene="Katnb1"
                     /note="katanin p80 (WD40-containing) subunit B 1; katanin
                     p80 (WD repeat containing) subunit B 1"
                     /codon_start=1
                     /product="katanin p80 WD40 repeat-containing subunit B1"
                     /protein_id="NP_001019917.1"
                     /db_xref="GeneID:291852"
                     /db_xref="RGD:1311256"
                     /translation="MATPVVTKTAWKLQEIVAHASNVSSLVLGKASGRLLATGGDDCR
                     VNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLM
                     GHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGK
                     WLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIRFWDL
                     EKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERCFDVVLVNWGKVA
                     DLAICNDQLIGVAFSQSNVSSYVVDLTRVTRTGTVTQDPVQASQPQTQQTPNPGVSLR
                     RIYERPSTTCSKPQRVKHNSESERRSPSSEDDKDERESRAEIQNAEDYNEIFQPKNSI
                     SRTPPRRSEPFPAPPEDDIATAKEASKPSPAMDVQLPVPSQEVPARPSVMTSTPAPKG
                     EPVIIPATRNEPIGLKASDFLPAVKVPQQAELVDEDAMSQIRKGHDTMCVVLTSRHKN
                     LDTVRAVWTTGDIKTSVDSAVAINDLSVVVDLLNIVNQKASLWKLDLCTTVLPQIEKL
                     LQSKYESYVQTGCTSLKLILQRFLPLITDILAAPPSVGVDISREERLHKCRLCFKQLK
                     SISGLVKSRSGLSGRHGSAFRELHLLMASLD"
     exon            455..585
                     /gene="Katnb1"
                     /inference="alignment:Splign:2.1.0"
     exon            586..703
                     /gene="Katnb1"
                     /inference="alignment:Splign:2.1.0"
     exon            704..804
                     /gene="Katnb1"
                     /inference="alignment:Splign:2.1.0"
     exon            805..846
                     /gene="Katnb1"
                     /inference="alignment:Splign:2.1.0"
     exon            847..930
                     /gene="Katnb1"
                     /inference="alignment:Splign:2.1.0"
     exon            931..1046
                     /gene="Katnb1"
                     /inference="alignment:Splign:2.1.0"
     exon            1047..1118
                     /gene="Katnb1"
                     /inference="alignment:Splign:2.1.0"
     exon            1119..1269
                     /gene="Katnb1"
                     /inference="alignment:Splign:2.1.0"
     exon            1270..1460
                     /gene="Katnb1"
                     /inference="alignment:Splign:2.1.0"
     exon            1461..1591
                     /gene="Katnb1"
                     /inference="alignment:Splign:2.1.0"
     exon            1592..1642
                     /gene="Katnb1"
                     /inference="alignment:Splign:2.1.0"
     exon            1643..1710
                     /gene="Katnb1"
                     /inference="alignment:Splign:2.1.0"
     exon            1711..1830
                     /gene="Katnb1"
                     /inference="alignment:Splign:2.1.0"
     exon            1831..1980
                     /gene="Katnb1"
                     /inference="alignment:Splign:2.1.0"
     exon            1981..2057
                     /gene="Katnb1"
                     /inference="alignment:Splign:2.1.0"
     exon            2058..2132
                     /gene="Katnb1"
                     /inference="alignment:Splign:2.1.0"
     exon            2133..2249
                     /gene="Katnb1"
                     /inference="alignment:Splign:2.1.0"
     exon            2250..2662
                     /gene="Katnb1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggctgattg gtgtatgaag tgaagtggga gggactctag accggaggtt ttgttgtgag
       61 ggtcggttgt caagcagcga ccaatcaggg caaaggatgg aggcaagtgg gggtcgcgcc
      121 tggagggaag ccttggcctc tagagctaca gcttcagccc agtgttgagc cgagatggcc
      181 caagcctgac attccatgat ctgggatcct gacctatgtg tacaggctgc tgcttgctag
      241 cggatgatct aaaccaccag gcagacctgg gccaggagag gaggactctc tgcctggatg
      301 tgtgggaact ccctgccaac ttgattgtcg gatctggggg ggatccaccc ccacccccac
      361 agagaaagca caatctgttt tgcgggtggg gtctcaggtg tcaccccctg aagcatggcc
      421 acccctgtgg tcaccaagac tgcctggaag ttacaagaga tcgtcgccca tgccagcaat
      481 gtgtcctcct tggtgctggg caaggcctcg gggcggctat tggccactgg tggggatgac
      541 tgtcgagtca acctgtggtc cataaacaag cctaactgta tcatgagtct gacaggtcac
      601 acgtcccccg tggagagtgt ccgcctcaac acccctgagg agctcatcgt agctggttcc
      661 cagtcgggct ccatccgcgt ctgggacctg gaagctgcta aaattcttcg aacactcatg
      721 ggccacaaag ccaacatctg cagcctggat ttccacccct atggcgaatt tgtggcctca
      781 ggttcccagg acacaaacat caagctttgg gacatcagga gaaaaggctg tgtcttccga
      841 tatagggggc acagccaggc tgtgcggtgt ctccggttca gccctgatgg gaagtggctg
      901 gcatcagcag cagatgacca cacagtgaag ctttgggatc tgacggctgg caagatgatg
      961 tccgagttcc ctggtcatac agggcctgtc aacgtggtgg agtttcaccc caatgaatat
     1021 ctccttgctt ctggcagctc cgacaggaca atccgcttct gggacctgga gaagttccag
     1081 gtggtgagct gcattgaagg ggagccgggg cctgtgagga gtgttctctt caaccctgat
     1141 ggctgctgcc tgtatagcgg ctgccaggac tcgctgcgtg tctacggctg ggagcctgag
     1201 cgctgctttg atgtggtcct tgtcaactgg ggcaaggtgg ctgacctggc catctgcaat
     1261 gaccagctga taggtgtggc tttctcccag agtaatgtct cctcttatgt ggtggacctg
     1321 acaagagtca ccaggacagg aactgtgacc caggaccctg tgcaagctag ccagcctcag
     1381 acacaacaga cccctaaccc tggtgtctcc cttcgccgca tctacgagcg gcccagcaca
     1441 acctgcagca agcctcagag ggtaaagcac aactcagaga gtgagcggcg cagccccagc
     1501 agtgaagatg acaaggatga gcgtgagtcg cgggccgaga tccagaatgc ggaggactac
     1561 aatgagatct tccagcccaa gaacagcatc agtcggacac cgccccggag aagtgagccc
     1621 ttcccagcgc ccccagaaga tgacatagcc acagcaaagg aggcctcgaa acccagccca
     1681 gccatggatg tgcagttgcc ggtgccaagt caggaggtcc cagcacgacc atcagtcatg
     1741 acttccactc ctgcacccaa gggtgagcct gtcatcatcc ctgccacgcg gaatgagccc
     1801 attggcctaa aggcctcgga cttcttgccc gccgtgaagg tcccccagca ggcagagctg
     1861 gtagatgagg atgccatgtc acagatccgc aaaggccacg acactatgtg cgtggtgctc
     1921 accagccgcc acaagaacct ggacactgtg cgagctgtgt ggaccacagg agatatcaag
     1981 acatcggtgg actctgcagt ggccatcaat gacctgtctg tggtcgtgga ccttctgaat
     2041 attgtcaacc agaaagcctc cctgtggaag ctggacctgt gcaccactgt gctgccccaa
     2101 attgagaaac ttctgcagag caagtatgag agctatgtcc agactgggtg tacctccctc
     2161 aagctgatcc tgcagcggtt cctacccctc atcactgaca ttttggcagc cccgccctct
     2221 gtgggtgtgg acatcagccg agaggagagg ctgcataagt gtcgactctg cttcaagcag
     2281 ctcaagagca tcagtggcct cgtcaagagc aggtcgggtt tgagcggccg ccatggcagt
     2341 gccttccgtg agctgcacct actcatggcc agtttggact gaggagctca tggtgggagc
     2401 accagcagcc ctcactggtt tggcctcaca ctctagtttg ctgtatgctc gtggcctgtg
     2461 agcctcagcc tggcctccac tcttgccccg atggccattc tggaggcatg gttgccagcc
     2521 tgctgaccac cttctcagat gtggactcag ttcctctccg cagtcttgta ccgcccctgc
     2581 ttctcagggc aacgccagcc ttggagctgc tgctgtaaat tatcaggcag atttattaaa
     2641 tttataactg ttcctgactt ca
//
