LOCUS       NP_001006957             488 aa            linear   ROD 03-APR-2024
DEFINITION  katanin p60 ATPase-containing subunit A-like 1 [Rattus norvegicus].
ACCESSION   NP_001006957 XP_213698
VERSION     NP_001006957.1
DBSOURCE    REFSEQ: accession NM_001006956.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 488)
  AUTHORS   Cheung,K., Senese,S., Kuang,J., Bui,N., Ongpipattanakul,C.,
            Gholkar,A., Cohn,W., Capri,J., Whitelegge,J.P. and Torres,J.Z.
  TITLE     Proteomic Analysis of the Mammalian Katanin Family of
            Microtubule-severing Enzymes Defines Katanin p80 subunit B-like 1
            (KATNBL1) as a Regulator of Mammalian Katanin Microtubule-severing
  JOURNAL   Mol Cell Proteomics 15 (5), 1658-1669 (2016)
   PUBMED   26929214
REFERENCE   2  (residues 1 to 488)
  AUTHORS   Smith,L.B., Milne,L., Nelson,N., Eddie,S., Brown,P., Atanassova,N.,
            O'Bryan,M.K., O'Donnell,L., Rhodes,D., Wells,S., Napper,D.,
            Nolan,P., Lalanne,Z., Cheeseman,M. and Peters,J.
  TITLE     KATNAL1 regulation of sertoli cell microtubule dynamics is
            essential for spermiogenesis and male fertility
  JOURNAL   PLoS Genet 8 (5), e1002697 (2012)
   PUBMED   22654668
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083673.1.
            
            On Nov 22, 2004 this sequence version replaced XP_213698.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083673.1, SRR8487231.74245.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132272, SAMD00132277
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12p11"
     Protein         1..488
                     /product="katanin p60 ATPase-containing subunit A-like 1"
                     /EC_number="5.6.1.1"
                     /note="p60 katanin-like 1; katanin p60 subunit A-like 1;
                     katanin p60 ATPase-containing subunit A-like 1-like"
                     /calculated_mol_wt=55070
     Site            1
                     /site_type="acetylation"
                     /note="N-acetylmethionine.
                     /evidence=ECO:0000250|UniProtKB:Q9BW62; propagated from
                     UniProtKB/Swiss-Prot (Q5XIK7.1)"
     Region          4..72
                     /region_name="Kp60-NTD"
                     /note="N-terminal domain (NTD) found in katanin p60 (Kp60)
                     ATPase-containing subunit A1, and similar proteins;
                     cd21748"
                     /db_xref="CDD:439297"
     Site            order(7,14,17..20,22,29,51,55,58..59,61..62,65..66,68..69,
                     72)
                     /site_type="other"
                     /note="heterodimer interface [polypeptide binding]"
                     /db_xref="CDD:439297"
     Region          52..452
                     /region_name="SpoVK"
                     /note="AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell
                     wall/membrane/envelope biogenesis, Cell cycle control,
                     cell division, chromosome partitioning, Signal
                     transduction mechanisms]; COG0464"
                     /db_xref="CDD:440232"
     Region          128..179
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5XIK7.1)"
     Site            172
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q5XIK7.1)"
     Region          207..376
                     /region_name="RecA-like_KTNA1"
                     /note="Katanin p60 ATPase-containing subunit A1; cd19522"
                     /db_xref="CDD:410930"
     Site            order(208..211,248..254)
                     /site_type="other"
                     /note="putative ATP binding site [chemical binding]"
                     /db_xref="CDD:410930"
     Region          <448..486
                     /region_name="Vps4_C"
                     /note="Vps4 C terminal oligomerization domain; pfam09336"
                     /db_xref="CDD:462762"
     CDS             1..488
                     /gene="Katnal1"
                     /coded_by="NM_001006956.1:81..1547"
                     /db_xref="GeneID:288449"
                     /db_xref="RGD:1359252"
ORIGIN      
        1 mnlaeicena kkgreyallg nydssmvyyq gviqqiqrhc qslrdpatka kwqqvrqell
       61 eeyeqvksiv stlesfkmdk ppdfpvscrd epfrdpavwp ppvpaehrap pqirrpnrev
      121 rplrkdmgag arglvgrahq isksdkaasr dkdyrargrd dkarknmqdg asdgeipkfd
      181 gagydkdlve alerdivsrn psihwddiad leeakkllre avvlpmwmpd ffkgirrpwk
      241 gvlmvgppgt gktmlakava tecgttffnv ssstltskyr geseklvrll femarfyapt
      301 tifideidsi csrrgtsdeh easrrvksel liqmdgvgga lenddpskmv mvlaatnfpw
      361 didealrrrl ekriyiplpt akgraellki slreveldpd ihlediaekt egysgaditn
      421 icrdaslmam rrringlspe eiralskeel qmpvtrgdle lalkkiaksv saadlekyek
      481 wmvefgsa
//
