LOCUS       XP_038949637            2039 aa            linear   ROD 22-FEB-2024
DEFINITION  histone acetyltransferase KAT6B isoform X1 [Rattus norvegicus].
ACCESSION   XP_038949637
VERSION     XP_038949637.1
DBLINK      BioProject: PRJNA1074393
DBSOURCE    REFSEQ: accession XM_039093709.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_086033) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_036323735.1-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/09/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..2039
                     /organism="Rattus norvegicus"
                     /strain="BN/NHsdMcwi"
                     /bio_material="RGD 61498"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /sex="male"
                     /tissue_type="kidney, spleen, liver"
                     /geo_loc_name="USA: Wisconsin, Milwaukee"
                     /lat_lon="43.05 N 88.04 W"
                     /collected_by="Rebecca Schilling, Melinda Dwinell"
     Protein         1..2039
                     /product="histone acetyltransferase KAT6B isoform X1"
                     /calculated_mol_wt=225774
     Region          94..168
                     /region_name="H15"
                     /note="Domain in histone families 1 and 5; smart00526"
                     /db_xref="CDD:197772"
     Site            151..162
                     /site_type="DNA binding"
                     /note="DNA-binding site [nucleotide binding]"
                     /db_xref="CDD:238028"
     Region          213..270
                     /region_name="PHD1_MOZ_MORF"
                     /note="PHD finger 1 found in monocytic leukemia
                     zinc-finger protein (MOZ) and its factor (MORF); cd15618"
                     /db_xref="CDD:277090"
     Site            order(216,218..219,221,238,243..245,250..252,265,267..269)
                     /site_type="other"
                     /note="histone H3 binding site [polypeptide binding]"
                     /db_xref="CDD:277090"
     Site            order(252,256,259..260,263,265..266,268,270)
                     /site_type="other"
                     /note="PHD2 interface [polypeptide binding]"
                     /db_xref="CDD:277090"
     Region          272..318
                     /region_name="PHD2_KAT6A_6B"
                     /note="PHD finger 2 found in monocytic leukemia
                     zinc-finger protein (MOZ) and its factor (MORF); cd15527"
                     /db_xref="CDD:277002"
     Site            order(272,277,290..294)
                     /site_type="other"
                     /note="PHD1 interface [polypeptide binding]"
                     /db_xref="CDD:277002"
     Site            order(284..290,293,308..311)
                     /site_type="other"
                     /note="histone H3 binding site [polypeptide binding]"
                     /db_xref="CDD:277002"
     Region          <721..989
                     /region_name="PLN00104"
                     /note="MYST -like histone acetyltransferase; Provisional"
                     /db_xref="CDD:215056"
     CDS             1..2039
                     /gene="Kat6b"
                     /coded_by="XM_039093709.2:2010..8129"
                     /db_xref="GeneID:688634"
                     /db_xref="RGD:1566399"
ORIGIN      
        1 mvklanplyt ewileavqki kkqkqrpsee richavstsh gldkktvseq lelsvqdgsv
       61 lkvtnkglas ykdpdhpgrf ssvkpgtfpk ptkgpkgppc ndlrnvdwnk llkraiegle
      121 epsgsslksi ekylrsqsdl tgttdhpafq qrlrlgakra vnngrllkdg pqyrvntgss
      181 dgrgapqyps afpsslppvs llphekdqpr adpipicsfc lgtkesnrek kpeelvscad
      241 cgssghpscl kfcpeltanv kalrwqciec ktcsacrvqg knadnmlfcd scdrgfhmec
      301 cdpplsrmpk gmwicqvcrp kkkgrkllhe kaaqikrrya kpigrpknkl kqrllsvtsd
      361 egsvnaftgr gspgrgqktk vcttpssgha asgkdsssrl avtdptrpga ttktttssty
      421 isastlkvnk ktkglidglt kfftpspdgr rsrgeiidfs khyrprkkvs qkqsctshml
      481 atgttqklkp ppsalpppap isgqspssqk sststssapt qssssrssep sfsslinssq
      541 lkalfdglsh iyttqgqsrk kghpsyappk rmrrktefss takakacffg krdfrsrfls
      601 hsscswgmtr ghifkaiahf krttflkkhr mlgrlkykvt pqmgtpspgk gsladgrinp
      661 dqdndteiki sikqesmdvn vmgnkdlvte edldvfkqaq elswekiece sgvedcgryp
      721 sviefgkyei qtwysspypq eyarlpklyl cefclkymks knillrhskk cgwfhppane
      781 iyrrkdlsvf evdgnmskiy cqnlcllakl fldhktlyyd vepflfyvlt kndekgchlv
      841 gyfskeklcq qkynvscimi mpqhqrqgfg rflidfsyll srregqagsp ekplsdlgrl
      901 sylaywksvi leylyrhher hisikaisra tgmcphdiat tlqylhmidr rdgrfviirr
      961 eklilghmek lkncsrpnev dpeslrwtpi lisnavvsee ereaekeaer lmeqascwek
     1021 eeqenlssrv tsrqssakvq sknkylhspe rrpvagergq llglskesse eeeeeedded
     1081 eeeeeeeees iptspprltk pqsvsikrkr pfvvkkkrgr krrrinssvt tetisettev
     1141 lnepfdnsde erpmprlept ceiqveeagr kpvlrkafqh qpgkkrqtee gdgkdnhffk
     1201 naalcrndvd ddaehleegs rdsaeplkcr qvwpkaakrg lskwrqsker rpglklnlct
     1261 ppetpmepeg ltkvvkeqkg isedkgspvg edrevtetee allpqdgngr eetgtpvsph
     1321 kspggkadee dlikgeeeee eegttekdpd gakskekaea eismekedav hlddheeded
     1381 eeeepshned hdaddeddgh meatnvdrgd lpkeafkdal egqeaflgls iqpshsdpeg
     1441 lvncggdlav scgsepkela gdagtapesd selpeeqtqe qdqeksngad telkdggtat
     1501 veidsetvqa vqsltqenre qddtfqdcae tqeacrslqn ythtdqspqi attldecqqs
     1561 dhsspvssvh shpgqsvrsv nspsvpalen syaqispdqt aitvpplqnm etspmmdvps
     1621 vsdhsqqvvd sgfsdlgsie sttenyenps sydstmggsi cgnsssqnsc sygsltsssl
     1681 tqsscavtqq msnisgscsm lqqtsisspp tcsvkspqgc vverppsssq qlaqcsmaan
     1741 ftppmqladi petsnanigl yermgqsdfg aghypqpsat fslaklqqlt ntlidhslpy
     1801 shsaaatsya nsaslstpls ntglvqlsqs phsvpggpqa qatmtpppnl tpppmnlppp
     1861 llqrnmaasn igishsqrlq tqiaskgpvs mrtksaslsp aaathqsqiy grsqtvamqg
     1921 partltmqrg mnmsvnlmpa paynvnsvnm nmntlnamng ysmsqpmmns gyhsnhgymn
     1981 qtpqypmqmq mgmmgtqpya qqpmqtpphs nmmytapghh gymntgmskq slngsymrr
//
