LOCUS       NM_001003711            4162 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus junctophilin 4 (Jph4), mRNA.
ACCESSION   NM_001003711 XM_008770690 XM_341317
VERSION     NM_001003711.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4162)
  AUTHORS   Woo,J.S., Srikanth,S., Nishi,M., Ping,P., Takeshima,H. and Gwack,Y.
  TITLE     Junctophilin-4, a component of the endoplasmic reticulum-plasma
            membrane junctions, regulates Ca2+ dynamics in T cells
  JOURNAL   Proc Natl Acad Sci U S A 113 (10), 2762-2767 (2016)
   PUBMED   26929330
REFERENCE   2  (bases 1 to 4162)
  AUTHORS   Kakizawa,S., Kishimoto,Y., Hashimoto,K., Miyazaki,T., Furutani,K.,
            Shimizu,H., Fukaya,M., Nishi,M., Sakagami,H., Ikeda,A., Kondo,H.,
            Kano,M., Watanabe,M., Iino,M. and Takeshima,H.
  TITLE     Junctophilin-mediated channel crosstalk essential for cerebellar
            synaptic plasticity
  JOURNAL   EMBO J 26 (7), 1924-1933 (2007)
   PUBMED   17347645
REFERENCE   3  (bases 1 to 4162)
  AUTHORS   Nishi,M., Sakagami,H., Komazaki,S., Kondo,H. and Takeshima,H.
  TITLE     Coexpression of junctophilin type 3 and type 4 in brain
  JOURNAL   Brain Res Mol Brain Res 118 (1-2), 102-110 (2003)
   PUBMED   14559359
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000015.1.
            
            On or before Dec 8, 2020 this sequence version replaced
            XM_008770690.2, NM_001003711.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.57077.1,
                                           SRR26643294.51918.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760393,
                                           SAMEA5760400 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-625               JAXUCZ010000015.1  32558235-32558859   c
            626-1175            JAXUCZ010000015.1  32557147-32557696   c
            1176-1947           JAXUCZ010000015.1  32555653-32556424   c
            1948-2066           JAXUCZ010000015.1  32552797-32552915   c
            2067-2599           JAXUCZ010000015.1  32551984-32552516   c
            2600-4162           JAXUCZ010000015.1  32549536-32551098   c
FEATURES             Location/Qualifiers
     source          1..4162
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p13"
     gene            1..4162
                     /gene="Jph4"
                     /note="junctophilin 4"
                     /db_xref="GeneID:445271"
                     /db_xref="RGD:1303170"
     exon            1..625
                     /gene="Jph4"
                     /inference="alignment:Splign:2.1.0"
     exon            626..1175
                     /gene="Jph4"
                     /inference="alignment:Splign:2.1.0"
     CDS             797..2683
                     /gene="Jph4"
                     /note="junctophilin-like 1 protein; JP-4"
                     /codon_start=1
                     /product="junctophilin-4"
                     /protein_id="NP_001003711.2"
                     /db_xref="GeneID:445271"
                     /db_xref="RGD:1303170"
                     /translation="MSPGGKFDFDDGGCYVGGWEAGRAHGYGVCTGPGAQGEYSGCWA
                     HGFESLGVFTGPGGHSYQGHWQQGKREGLGVERKSRWTYRGEWLGGLKGRSGVWESVS
                     GLRYAGLWKDGFQDGYGTETYSDGGTYQGQWQAGKRHGYGVRQSVPYHQAALLRSPRR
                     TSLDSGHSDPPTPPPPLPLPGDEGGSPASGSRGGFVLAGPGDADGASSRKRTPAAGGF
                     FRRSLLLSGLRAGGRRSSLGSKRGSLRSEVSSEVGSTGPPGSEASGPPIPAPPALIEG
                     SATEVYAGEWRADRRSGYGVSQRSNGLRYEGEWLGNRRHGYGRTTRPDGSREEGKYKR
                     NRLVHGGRVRSLLPLALRRGKVKEKVDRAVEGARRAVSAARQRQEIAAARAADALLKA
                     VAASSVAEKAVEAARMAKLIAQDLQPMLEAPGRRPRQDSGGSDTEPLDEDSPGVYENG
                     LTPSEGSPELPSSPASSHQPWRAPPCRSPLPPGGNWGPFSSPKAWPEEWGGPGEQAEE
                     LAGYEAEDEAGMQGPGPRDGSPLLGGCSDSSGSLREEEGEDEESLPQLRAPGGSESEP
                     VTTPVLRGLSSRGPDAGCLTEEFEEPAATERPAQPGAANPLVVGAVALLDLSLAFLFS
                     QLLT"
     exon            1176..1947
                     /gene="Jph4"
                     /inference="alignment:Splign:2.1.0"
     exon            1948..2066
                     /gene="Jph4"
                     /inference="alignment:Splign:2.1.0"
     exon            2067..2599
                     /gene="Jph4"
                     /inference="alignment:Splign:2.1.0"
     exon            2600..4162
                     /gene="Jph4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actccctgcc ggcaagccag ggtttctttc caccgtgggg gtctctgagc ctcccattct
       61 cccctctgcc tgccttctcc ctcacctcaa gggtagcgag cccccatttt ttttctgcct
      121 gagcatcctc tcaccacccc cactgccagt gactctctcc ccaccctctc ctctccgctc
      181 ctctctgccc ctttaaatct gcctggccca acctccccct tgatgctggg tttggagcaa
      241 acattgattt gtgctcggat ggaattggaa ttttgatttt tttcccctct cccaaccata
      301 agaagaaaaa aataaaacac cccctcttga tagccccctc ctctttccca tccagctccc
      361 agctcctctt tgctgcctcc gttcaaggca gattttttcc ccctacactt attcccctcc
      421 accttgccac tacctcaccc cccacactag cctgcacctt cagccgagga gaggggactc
      481 ttccatagct cccccacttc cttctctggg ttgtagcagt ctctccggaa gggaaggggg
      541 cttggtttgt ccgggtgagg tgtgagtgga gggaccctga catggaaact gcgcccggga
      601 ggcagcctga gccccagctc acatgccact caggatgagg gtccggccct gcctgcccgc
      661 gctggggccc ctccgcccag ccccggtcta actgcccccg ccccaaggcc tcgcccggcc
      721 cccaggcccc cagccggctt tccagcccca ggatgcgctg agctgccggg gggctgaggc
      781 cacgccaact acatgcatgt cccccggggg caagttcgac tttgacgacg ggggctgcta
      841 cgtggggggc tgggaggcgg ggcgggcaca tggctacggc gtgtgcaccg ggcccggcgc
      901 ccagggagag tacagcggct gctgggctca cggcttcgag tcgctgggtg tcttcacggg
      961 gcccggcgga cacagttacc agggccactg gcagcagggc aagcgcgaag ggctgggcgt
     1021 ggagcgcaag agccgctgga cctaccgcgg cgagtggctg ggcgggctga aggggcgcag
     1081 cggcgtgtgg gagagcgtgt ccggcctgcg ctacgccggg ctctggaagg acggcttcca
     1141 ggacggctac ggcaccgaga cctactccga tggaggcact taccaaggcc agtggcaagc
     1201 cggaaaacgc catggctacg gggtacgcca gagtgtaccc taccaccagg cggcgcttct
     1261 gcgctcaccc cgccgcacct ccctggactc cggccacagc gaccccccga cgccgcctcc
     1321 acccctaccc ctaccaggag atgaaggagg cagccctgcc tccggctcca gaggcggctt
     1381 cgtactggcg gggccagggg acgccgatgg ggcgtcttcc cgtaagcgca ccccagcagc
     1441 aggtggattc ttccgccgtt cactgctgct cagcgggctc cgggctggtg ggcgccgcag
     1501 ctccctgggc agcaagaggg gatcactacg aagcgaggtg agcagcgaag tgggcagtac
     1561 aggacccccg ggctccgagg ccagcgggcc ccctatccca gcgccacctg ccctcatcga
     1621 gggctctgcc actgaggtgt acgccggtga gtggcgtgcg gaccggcgca gtggctacgg
     1681 agtgagccag agatccaacg ggctgcgcta tgaaggcgag tggctgggca accgacggca
     1741 cggatacggg cgcaccaccc ggcccgatgg ctcccgtgag gagggcaagt acaagcgcaa
     1801 ccggctggta cacgggggac gtgtccgcag cctcctgcct ctggccctta gacggggcaa
     1861 agtcaaggag aaagtggaca gggctgtcga aggtgcccgt cgagctgtga gtgctgcccg
     1921 ccagcgccag gaaattgctg ctgccagggc agcagacgcc ctcctcaaag cagtggcagc
     1981 cagcagcgtc gcggagaagg ccgtggaggc ggcgcggatg gccaagctga tagcccagga
     2041 tctacaaccc atgttagagg ccccaggccg cagaccccga caggattctg gaggttctga
     2101 cacagagcct ttggatgagg acagccccgg ggtatacgag aatggactga ccccctcaga
     2161 gggatctccg gaactgccca gcagccctgc ttcctcccac caaccttggc gggcccctcc
     2221 ctgccggagc ccactgcctc ccggagggaa ctggggcccc ttctccagtc ctaaagcttg
     2281 gcctgaggag tgggggggtc ctggtgagca ggcagaggaa ctggctggct atgaggctga
     2341 ggatgaggct gggatgcagg gtccaggacc gagagatggt tccccacttc tcggaggctg
     2401 cagtgacagt tcaggaagtc ttcgagagga ggaaggggaa gatgaagagt ccttgcccca
     2461 gctgagggcc ccaggaggct cagaatctga gcctgtcacc actccagttt tgaggggcct
     2521 gtcttcaagg ggtcctgatg ctgggtgcct gacagaagag tttgaggagc ctgctgccac
     2581 cgagaggcct gcccagccgg gagctgccaa ccccctggtg gtaggagctg tggccttgct
     2641 ggatctcagc ctggcgttcc tgttctccca gctcctcacc tgaggcaaca tcctggcttc
     2701 ctccggcttg gttgcctgcc tctgcaccca ctctgacctt tgacctgcct tctcttctct
     2761 cctcctccac ctacctgtgt tttccccttt cctttctccc aggccccttt ctttttgtct
     2821 cttgcttctt ccttccctct attctttgag atggtctcat ttattctgga cctgtctctg
     2881 gtcttcctgg ttttctttcc caccccaacc cctctttctc tagattgttt acatatgaag
     2941 ggctgttctc tctcagagtt gctctctcct ctgagataca caaatctaag tcagaccatt
     3001 gccccccatg tcctccccaa ccttttattt gaatcaaaac ttcaccaagg gtaggggttt
     3061 ggtgtcctaa ggaatctcct ggaatctgag tggaagggag aaagagaaca cttatgaagt
     3121 gactgagtgg ccagactagg cactggctga gccacttggg gctcactggc ccccatggaa
     3181 agcttcaggg agagtaccct ccactcttac ctcccagaac ctacctaagt tcttgcctaa
     3241 ttcaatcctt ccctgaggga gaaaagggga gcgaacaaca ggaagctccc catgctccct
     3301 ctcctgtcct cctcagccag tccctctccc aacccccaag gatggcacgc caagccaaga
     3361 gcaatgggca aagcaacgaa aaccatctgg tacaccaagc ccgcccctct cagactctgc
     3421 cactcacctc tctacccttc tccgccccct gaaaatttat ttggttggtc tggactcact
     3481 tgtggccttt gattaaattc ctaaggggcc tgaagaagac atttctgccc agggtcagag
     3541 gcactgcagc aagcagggac cccactccag ctctggcggt tgtggggagc acacggaaga
     3601 cgaggactga agggcagcaa atgctgccac aagtctagtt cccaagccct cacatagact
     3661 cctgtgaggt gggaaaataa aggggatctg aggaactcgc tcgctgtctc ccacactttc
     3721 aggcagggca gaggtgggtg tcatccccag atgagaggtg ggtgaagagc ctgtctgaga
     3781 tacgcttgat ccatcgtcac tagcttatcc tctggggaca gaaagctcta caagagggaa
     3841 ctgtagaagc ccgggggact ctccttccct gcatgaggca gaggcaagcg gcctgccaat
     3901 cccctcctca aggaacggcc ttgcctggga atgcccacca cacaaccttc ttatttttct
     3961 agtcaacctc tgtttactcc ctggcctgcc ttcctcccgc cttccttcct tccttccttc
     4021 tcgatcttta cttctgattt ctatttcatg gaatttggga ttgacgttat acaacagtgc
     4081 cgacaacatc aagtcttgca ggaaaaaaaa aatacaaaga aatttaacaa aaaaaagtat
     4141 attaataaaa aagttccaaa aa
//
