LOCUS       NM_001106256             868 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus Josephin domain containing 2 (Josd2), mRNA.
ACCESSION   NM_001106256 XM_001080592 XM_214929
VERSION     NM_001106256.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 868)
  AUTHORS   Weeks SD, Grasty KC, Hernandez-Cuebas L and Loll PJ.
  TITLE     Crystal structure of a Josephin-ubiquitin complex: evolutionary
            restraints on ataxin-3 deubiquitinating activity
  JOURNAL   J Biol Chem 286 (6), 4555-4565 (2011)
   PUBMED   21118805
REFERENCE   2  (bases 1 to 868)
  AUTHORS   Ahmed F, Torrado M, Zinovieva RD, Senatorov VV, Wistow G and
            Tomarev SI.
  TITLE     Gene expression profile of the rat eye iridocorneal angle: NEIBank
            expressed sequence tag analysis
  JOURNAL   Invest Ophthalmol Vis Sci 45 (9), 3081-3090 (2004)
   PUBMED   15326124
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from DV214517.1 and
            CK842299.1.
            
            On Oct 11, 2007 this sequence version replaced NM_001106256.1.
            
            ##Evidence-Data-START##
            CDS exon combination :: CO396645.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMD00132261, SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-599               DV214517.1         1-599
            600-868             CK842299.1         1-269               c
FEATURES             Location/Qualifiers
     source          1..868
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="W"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q22"
     gene            1..868
                     /gene="Josd2"
                     /gene_synonym="RGD1307305"
                     /note="Josephin domain containing 2"
                     /db_xref="GeneID:292876"
                     /db_xref="RGD:1307305"
     exon            1..120
                     /gene="Josd2"
                     /gene_synonym="RGD1307305"
                     /inference="alignment:Splign:2.1.0"
     exon            121..283
                     /gene="Josd2"
                     /gene_synonym="RGD1307305"
                     /inference="alignment:Splign:2.1.0"
     CDS             138..704
                     /gene="Josd2"
                     /gene_synonym="RGD1307305"
                     /EC_number="3.4.19.12"
                     /codon_start=1
                     /product="josephin-2"
                     /protein_id="NP_001099726.2"
                     /db_xref="GeneID:292876"
                     /db_xref="RGD:1307305"
                     /translation="MSQAPEARPRSPSVYHERQRLELCAVHALNNVLQEQLFSQEAAD
                     EICKRLAPDSRLNPHRSLLGTGNYDVNVIMAALQGLGLAAVWWDRRRPLSQLVLPQVL
                     GLILNLPSPVSLGLLSLPLRRRHWVALRQVDGIYYNLDSKLRAPEALGGEDGVRAFLA
                     AALAQGLCEVLLVVTKEVEEAGCWLHTS"
     exon            284..409
                     /gene="Josd2"
                     /gene_synonym="RGD1307305"
                     /inference="alignment:Splign:2.1.0"
     exon            410..604
                     /gene="Josd2"
                     /gene_synonym="RGD1307305"
                     /inference="alignment:Splign:2.1.0"
     exon            605..851
                     /gene="Josd2"
                     /gene_synonym="RGD1307305"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgcgcgcaa gttgccggga gctgtagtcc gttccgcctg ctcagtcagc gtggtaccac
       61 ccgaaagccg cctagggaat gcgaaagcgg ccggtcccag ggagcggaaa ggccggcggg
      121 caggagctga ggagggcatg tctcaggcgc cggaagcgag accaagatca ccctcagtgt
      181 atcacgagcg gcagcggcta gagctgtgtg ccgttcatgc tctcaacaac gtcctccaag
      241 agcagctctt tagccaggaa gctgccgacg aaatctgcaa gaggctagcc ccagattccc
      301 ggctgaaccc ccatcgcagt ctcttgggca ccggcaacta tgatgtcaac gtgatcatgg
      361 ctgccctgca gggcctgggc ctggccgctg tgtggtggga caggaggaga cccctgtccc
      421 agctggtcct gccccaggta ctaggcctga tcttgaacct accctctcct gtgtcgctgg
      481 ggctgctgtc cctgccgctg cgccggcgac actgggtggc cctgcgccag gtggacggca
      541 tctactataa tctggactca aagctacggg cacctgaagc cctggggggc gaggatggtg
      601 tcagagcctt cctggcagct gccttggctc aaggcctgtg cgaggtgcta ttggtggtga
      661 ccaaggaggt ggaggaggct ggctgctggc tgcacacaag ctgatgtact gcctgggaag
      721 ggttgcctgc tgccgttcct gtgtccagtg cctgaaaaga acctgtaact tcaggcctca
      781 ggaggcctgt cctgccccag tgtccccgct cccctgacca ctgctgcctc aataaatctg
      841 ctcttttgtt aaaaaaaaaa aaaaaaaa
//
