LOCUS       NM_001014116            2225 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus jumonji domain containing 8 (Jmjd8), mRNA.
ACCESSION   NM_001014116 XM_340772
VERSION     NM_001014116.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2225)
  AUTHORS   Yeo,K.S., Tan,M.C., Lim,Y.Y. and Ea,C.K.
  TITLE     JMJD8 is a novel endoplasmic reticulum protein with a JmjC domain
  JOURNAL   Sci Rep 7 (1), 15407 (2017)
   PUBMED   29133832
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2225)
  AUTHORS   Yeo,K.S., Tan,M.C., Wong,W.Y., Loh,S.W., Lam,Y.L., Tan,C.L.,
            Lim,Y.Y. and Ea,C.K.
  TITLE     JMJD8 is a positive regulator of TNF-induced NF-kappaB signaling
  JOURNAL   Sci Rep 6, 34125 (2016)
   PUBMED   27671354
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2225)
  AUTHORS   Boeckel,J.N., Derlet,A., Glaser,S.F., Luczak,A., Lucas,T.,
            Heumuller,A.W., Kruger,M., Zehendner,C.M., Kaluza,D.,
            Doddaballapur,A., Ohtani,K., Treguer,K. and Dimmeler,S.
  TITLE     JMJD8 Regulates Angiogenic Sprouting and Cellular Metabolism by
            Interacting With Pyruvate Kinase M2 in Endothelial Cells
  JOURNAL   Arterioscler Thromb Vasc Biol 36 (7), 1425-1433 (2016)
   PUBMED   27199445
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079205.1.
            
            On Apr 20, 2005 this sequence version replaced XM_340772.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079205.1, FQ110973.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation,
                                                expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2225
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q12"
     gene            1..2225
                     /gene="Jmjd8"
                     /gene_synonym="RGD1307381"
                     /note="jumonji domain containing 8"
                     /db_xref="GeneID:360498"
                     /db_xref="RGD:1307381"
     exon            1..319
                     /gene="Jmjd8"
                     /gene_synonym="RGD1307381"
                     /inference="alignment:Splign:2.1.0"
     CDS             222..1037
                     /gene="Jmjd8"
                     /gene_synonym="RGD1307381"
                     /note="jmjC domain-containing protein 8; jumonji
                     domain-containing protein 8"
                     /codon_start=1
                     /product="jmjC domain-containing protein 8 precursor"
                     /protein_id="NP_001014138.1"
                     /db_xref="GeneID:360498"
                     /db_xref="RGD:1307381"
                     /translation="MLMAAAGRFGLLLLIVLWTMVTVVLPASGEGGWKQSRLGTEAAV
                     MEEERCTVERRAHLTYSEFMQHYAFLKPVILQGLTDNSKFRALCSRENLLASFGDNVV
                     RLSTANTYSYQKVDLPFQEYVEQLLHPQDPESLGNDTLYFFGDNNFTEWAPLFQHYRP
                     PPFRLLGTTPAYSFGIAGAGSGVPFHWHGPGFSEVIYGRKRWFLYPPEKTPEFHPNKT
                     TLAWLLEIYPSLAPSARPLECTIQAGEALYFPDRWWHATLNLDTSVFISTFLG"
     exon            320..418
                     /gene="Jmjd8"
                     /gene_synonym="RGD1307381"
                     /inference="alignment:Splign:2.1.0"
     exon            419..467
                     /gene="Jmjd8"
                     /gene_synonym="RGD1307381"
                     /inference="alignment:Splign:2.1.0"
     exon            468..564
                     /gene="Jmjd8"
                     /gene_synonym="RGD1307381"
                     /inference="alignment:Splign:2.1.0"
     exon            565..633
                     /gene="Jmjd8"
                     /gene_synonym="RGD1307381"
                     /inference="alignment:Splign:2.1.0"
     exon            634..753
                     /gene="Jmjd8"
                     /gene_synonym="RGD1307381"
                     /inference="alignment:Splign:2.1.0"
     exon            754..821
                     /gene="Jmjd8"
                     /gene_synonym="RGD1307381"
                     /inference="alignment:Splign:2.1.0"
     exon            822..956
                     /gene="Jmjd8"
                     /gene_synonym="RGD1307381"
                     /inference="alignment:Splign:2.1.0"
     exon            957..2196
                     /gene="Jmjd8"
                     /gene_synonym="RGD1307381"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caatggctgc tcaatacagt ttcactccgc cttgaggaaa tgattaaata ggggttttgt
       61 gtggatgtgg atgtttgtac tcgcgcgtgt acgaggagga ggctcccagg gccggctggc
      121 tactgcttgc aggtagctac agcagtccag accctaagcc aatggcttgt gctttcgtaa
      181 gtgtcgacag aattcccagc gtgctgcgcg cctgcacccg tatgctcatg gcggcggctg
      241 gacgattcgg tctgcttttg ctcattgtac tatggacgat ggtgactgtg gttctgcctg
      301 cctctggcga agggggatgg aaacagagta ggctgggaac tgaagcagcg gtgatggagg
      361 aggaacgttg cacagtcgag cgccgagcac acctcacgta ctccgaattt atgcagcact
      421 atgccttcct caagcccgtc atcttgcaag gactcacaga caactcgaag ttcagagccc
      481 tgtgttcccg ggaaaacctg ctggcctcgt ttggggacaa tgttgttcgc ttgagtacag
      541 ccaacaccta ctcctaccag aaagtggacc tgcctttcca ggaatatgtg gagcagctgc
      601 tgcaccccca ggaccccgaa tctctaggca atgacaccct gtactttttc ggagataaca
      661 actttactga gtgggcccca ctcttccaac attaccgtcc acctccattt cgtctactgg
      721 gaaccacccc tgcttatagc tttggaattg caggagctgg atctggggta cccttccact
      781 ggcatgggcc tggtttctca gaggttatct atggtcggaa gcgctggttc ctctaccctc
      841 ctgagaagac acctgagttc caccctaaca agaccacgtt ggcctggctc ctggaaatat
      901 acccatctct agccccatca gctcggcctc tagaatgtac catccaggct ggtgaagcgc
      961 tgtactttcc tgatcggtgg tggcatgcca cactcaatct ggacaccagt gtcttcatat
     1021 ccactttcct tggctagcca acaagcgact ggcaagccca ctgcaccagc acatgccaat
     1081 gtagtgctca cagactttat tacaggacag tggcagcagc agcagcaacc caccctcacc
     1141 agctctccag cccagaaggg agacaaggga ggctcatggc ccagcaaggg atatgctgag
     1201 aaggggagca gttcagaacc catcatcagg accgatgggg gcaggcccag ggacacaaac
     1261 tatatacagg gactggagct tctgcctcca gaccctcctg ggccagggtg ccaggcagga
     1321 catggggtat cagtagtcct ctacccagcc attctcagag atgaaagcat caatgacttc
     1381 cttcatggct aagttgggga tgagctgttc ctgggtcaga gggctccggg tcacaggatc
     1441 gaaatggccc acgcgctgca acgacagagt caagagtatt caatggcctg agtgtcccct
     1501 gatcccagtc ccgagaccac aggccctcct tacctgcagg tgctcctcaa tgtccttgcg
     1561 gtcataggtg atgccactgg gtgtaatgca gggttcccgc atcagctcaa agctgatctt
     1621 gccacacaag tagtcaggga tatctcgctt ctgcagcaca agagggaaat gtctgcaact
     1681 ggaaaggaag tcaccatacc agagcctgcc catgagcttc aaggctccgt ccttaccttt
     1741 cttttctcat ccacctgaga gaagagctca ttcatgtccg ccatgtattt atcctgcaga
     1801 gttgagcgcc atgtgtgggc aactcctgtc tcctccacac agacacacac actctgtcca
     1861 ccggggcact catgtcatgc atgggccaac agagccacca taggctgggg cacttctcat
     1921 gccacacaca aaaacacaca cacaacgacc cacatgtgga ctaggggcac cctcacgtgc
     1981 ttggcctcaa tgcaggcctg ctgggccctg atgtggccat catcctcatc accctcgtgg
     2041 ttccgctgac actcttccag ttccctgagg gtcaagaaaa agccagctgg tgatggcccc
     2101 aacagggaaa tgacagatcc cttcccatct caggcctctt tcctcccggg cttcccatgt
     2161 accggctgct gtcctttaat aaacacttgc actgttaaaa aaaaaaaaaa aaaaaaaaaa
     2221 aaaaa
//
