LOCUS       NM_001415052            5533 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus jade family PHD finger 1 (Jade1), mRNA.
ACCESSION   NM_001415052 XM_006232302
VERSION     NM_001415052.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5533)
  AUTHORS   Siriwardana,N.S., Meyer,R., Havasi,A., Dominguez,I. and
            Panchenko,M.V.
  TITLE     Cell cycle-dependent chromatin shuttling of HBO1-JADE1 histone
            acetyl transferase (HAT) complex
  JOURNAL   Cell Cycle 13 (12), 1885-1901 (2014)
   PUBMED   24739512
REFERENCE   2  (bases 1 to 5533)
  AUTHORS   Foy,R.L., Chitalia,V.C., Panchenko,M.V., Zeng,L., Lopez,D.,
            Lee,J.W., Rana,S.V., Boletta,A., Qian,F., Tsiokas,L., Piontek,K.B.,
            Germino,G.G., Zhou,M.I. and Cohen,H.T.
  TITLE     Polycystin-1 regulates the stability and ubiquitination of
            transcription factor Jade-1
  JOURNAL   Hum Mol Genet 21 (26), 5456-5471 (2012)
   PUBMED   23001567
REFERENCE   3  (bases 1 to 5533)
  AUTHORS   Borgal,L., Habbig,S., Hatzold,J., Liebau,M.C., Dafinger,C.,
            Sacarea,I., Hammerschmidt,M., Benzing,T. and Schermer,B.
  TITLE     The ciliary protein nephrocystin-4 translocates the canonical Wnt
            regulator Jade-1 to the nucleus to negatively regulate beta-catenin
            signaling
  JOURNAL   J Biol Chem 287 (30), 25370-25380 (2012)
   PUBMED   22654112
REFERENCE   4  (bases 1 to 5533)
  AUTHORS   Doyon,Y., Cayrou,C., Ullah,M., Landry,A.J., Cote,V., Selleck,W.,
            Lane,W.S., Tan,S., Yang,X.J. and Cote,J.
  TITLE     ING tumor suppressor proteins are critical regulators of chromatin
            acetylation required for genome expression and perpetuation
  JOURNAL   Mol Cell 21 (1), 51-64 (2006)
   PUBMED   16387653
REFERENCE   5  (bases 1 to 5533)
  AUTHORS   Zhou,M.I., Wang,H., Ross,J.J., Kuzmin,I., Xu,C. and Cohen,H.T.
  TITLE     The von Hippel-Lindau tumor suppressor stabilizes novel plant
            homeodomain protein Jade-1
  JOURNAL   J Biol Chem 277 (42), 39887-39898 (2002)
   PUBMED   12169691
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Dec 21, 2022 this sequence version replaced XM_006232302.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643429.7913.1,
                                           SRR26643297.7540.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-159               JAXUCZ010000002.1  126471124-126471282
            160-237             JAXUCZ010000002.1  126489118-126489195
            238-323             JAXUCZ010000002.1  126496165-126496250
            324-481             JAXUCZ010000002.1  126498858-126499015
            482-669             JAXUCZ010000002.1  126500855-126501042
            670-881             JAXUCZ010000002.1  126503938-126504149
            882-1049            JAXUCZ010000002.1  126507193-126507360
            1050-1166           JAXUCZ010000002.1  126508331-126508447
            1167-1688           JAXUCZ010000002.1  126511673-126512194
            1689-1806           JAXUCZ010000002.1  126516933-126517050
            1807-5533           JAXUCZ010000002.1  126520526-126524252
FEATURES             Location/Qualifiers
     source          1..5533
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q26"
     gene            1..5533
                     /gene="Jade1"
                     /gene_synonym="Phf17"
                     /note="jade family PHD finger 1"
                     /db_xref="GeneID:310352"
                     /db_xref="RGD:1306920"
     exon            1..159
                     /gene="Jade1"
                     /gene_synonym="Phf17"
                     /inference="alignment:Splign:2.1.0"
     exon            160..237
                     /gene="Jade1"
                     /gene_synonym="Phf17"
                     /inference="alignment:Splign:2.1.0"
     CDS             186..2684
                     /gene="Jade1"
                     /gene_synonym="Phf17"
                     /note="PHD finger protein 17"
                     /codon_start=1
                     /product="protein Jade-1"
                     /protein_id="NP_001401981.1"
                     /db_xref="GeneID:310352"
                     /db_xref="RGD:1306920"
                     /translation="MKRGRLPSSSEDSDDNGSLSTTWSQHSRSQHGRSTCSRHEDRKP
                     SEVFRTDLITAMKLHDSYQLNPDEYYVLADPWRQEWEKGVQVPVSPGTIPQPVARVVS
                     EEKSLMFIRPKKYIASSGSEPPELGYVDIRTLADSVCRYDLNDMDAAWLELTNEEFKE
                     MGMPELDEYTMERVLEEFEQRCYDNMNHAIETEEGLGIEYDEDVVCDVCQSPDGEDGN
                     EMVFCDKCNICVHQACYGILKVPEGSWLCRTCALGVQPKCLLCPKKGGAMKPTRSGTK
                     WVHVSCALWIPEVSIGSPEKMEPITKVSHIPSSRWALVCSLCNEKFGASIQCSVKNCR
                     TAFHVTCAFDRGLEMKTILAENDEVKFKSYCPKHSSHRKPEESLGEGAAQENGATECS
                     PQSPLEPFASLEQNREEAHRVSVRKQKLQQLEDEFYTFVNLLDVARALRLPEEVVDFL
                     YQYWKLKRKINFNKPLITPKKDEEDNLAKREQDVLFRRLQLFTHLRQDLERVRNLTYM
                     VTRREKIKRSVCKVQEQIFSLYAKLLEQGKVSGVPSSCSSLENMLLFNSPSVGPNVPK
                     IEDLKWHSAFFRKQMGTNLVHSLKKSHKRDALQNSSGTEGKTLLKQPGLSGRREGSGV
                     PESLLSFEKTFAEARLISSAQQKNGVVTPDHGKRRDNRFHCDLVKGDLKDKSFKQSHK
                     PLRSTDTSQRHLDNTRAATSPGVGQSAPGTRKEIVPKCNGSLVKVPTTPASPVKSWGG
                     FRIPKKGERQQQGEAHDGACHQHSDCSHLGISRAPAKERSKSRLRTDSENDGYAPDGE
                     MSDSESEASEKKCIHASSTISRRTDIIRRSILAS"
     exon            238..323
                     /gene="Jade1"
                     /gene_synonym="Phf17"
                     /inference="alignment:Splign:2.1.0"
     exon            324..481
                     /gene="Jade1"
                     /gene_synonym="Phf17"
                     /inference="alignment:Splign:2.1.0"
     exon            482..669
                     /gene="Jade1"
                     /gene_synonym="Phf17"
                     /inference="alignment:Splign:2.1.0"
     exon            670..881
                     /gene="Jade1"
                     /gene_synonym="Phf17"
                     /inference="alignment:Splign:2.1.0"
     exon            882..1049
                     /gene="Jade1"
                     /gene_synonym="Phf17"
                     /inference="alignment:Splign:2.1.0"
     exon            1050..1166
                     /gene="Jade1"
                     /gene_synonym="Phf17"
                     /inference="alignment:Splign:2.1.0"
     exon            1167..1688
                     /gene="Jade1"
                     /gene_synonym="Phf17"
                     /inference="alignment:Splign:2.1.0"
     exon            1689..1806
                     /gene="Jade1"
                     /gene_synonym="Phf17"
                     /inference="alignment:Splign:2.1.0"
     exon            1807..5533
                     /gene="Jade1"
                     /gene_synonym="Phf17"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccgccagcc gcacgcccta ccgggagggc ctgggcgcgc cgggccggcc gagcgcgcgg
       61 gcgacagcag gggctcgccc ggctccccgc gcggcctctg tggcccggac tcatgcggcg
      121 cagcgtgcag cccgcggagg cccagcccgt gcgcagcagg ctgtctgctg tctcccgggg
      181 agatcatgaa acgaggtcgc cttcccagca gcagtgagga ttctgacgac aatggcagct
      241 tgtcaacgac gtggtcccag cattctcggt cccagcatgg gaggagtacc tgctctagac
      301 atgaagatcg aaagccttct gaggtgttta ggacggacct gatcactgcc atgaagctgc
      361 atgactccta ccagctgaac ccggatgagt actacgtgtt ggctgatccc tggagacagg
      421 aatgggagaa gggggtccag gtgcctgtga gcccagggac catcccacag cctgtggcca
      481 gggttgtgtc tgaagagaaa tcactcatgt tcatcaggcc caagaagtac atcgcgtcgt
      541 caggctccga gcccccagag ctgggctatg ttgatatccg gacactggca gacagtgtat
      601 gtcggtatga cctcaatgat atggatgctg catggctgga actaaccaat gaagaattta
      661 aggagatggg gatgccggaa ctggatgagt acaccatgga aagggtcttg gaggagtttg
      721 aacagcgatg ctatgacaat atgaatcatg ccatagagac agaagagggc ttggggatcg
      781 aatatgatga agacgttgtc tgcgatgtct gccagtcacc tgatggcgag gacggcaacg
      841 agatggtatt ctgtgacaag tgtaacatct gtgtgcacca ggcttgctat ggaatcctta
      901 aggtgccaga gggcagttgg ctatgccgta catgtgccct gggagttcag ccaaaatgtt
      961 tgctgtgtcc caagaaaggc ggagctatga agcctacccg cagtggaacc aagtgggtcc
     1021 atgtcagctg tgccctgtgg atccctgagg taagcattgg cagccctgag aagatggagc
     1081 ccatcacaaa agtgtcccac attccgagca gtcgatgggc gcttgtgtgc agcctctgca
     1141 atgagaaatt tggggcctcc atacagtgct ctgtgaagaa ctgccggaca gccttccatg
     1201 tgacttgtgc ttttgaccgt ggcctggaga tgaagaccat attggcagag aatgatgaag
     1261 tcaaattcaa gtcctactgc ccaaagcaca gctcacacag gaaacctgag gagagcctgg
     1321 gtgaaggagc agcccaggag aatggggcca ctgagtgttc tccccagagc cctctggagc
     1381 cctttgctag tctggagcag aatcgagagg aggcccaccg tgtgagtgtt cgcaagcaga
     1441 agctacagca gctggaggat gagttctaca cctttgtcaa cctgctggat gtggccaggg
     1501 ccctgcgact gcctgaggaa gtggtggatt ttctgtacca gtactggaag ctgaagagga
     1561 agatcaactt caacaagccc ctcatcactc caaagaaaga cgaagaggac aatctagcca
     1621 agcgggagca ggatgtcttg tttaggaggc tgcagctgtt cacgcacctg cggcaggacc
     1681 tggagagggt tcggaacctc acttacatgg tgacccgcag ggaaaagatt aaacggtctg
     1741 tgtgcaaagt ccaggaacag attttcagtc tttacgctaa gctcttggag caaggaaaag
     1801 tttcaggtgt gccttcttcc tgctcctcac tggagaacat gcttttgttc aacagtcctt
     1861 ctgtgggccc caatgttccc aagatagagg acttgaagtg gcattctgca ttcttcagga
     1921 aacaaatggg tactaacttg gttcattcac tgaaaaagtc ccataagcga gatgcattgc
     1981 agaacagttc tgggactgag ggaaagaccc tgctaaagca gccaggtctg tctggtagga
     2041 gggaggggtc gggggtccca gaaagccttc tgagctttga aaagactttt gcagaagcac
     2101 gtctcatatc atcagcacaa cagaaaaatg gtgtggtgac cccagaccat gggaaaagaa
     2161 gagacaatcg ttttcattgt gatcttgtta aaggagactt aaaggacaaa tcttttaaac
     2221 agagtcacaa gcctctcagg tctacagaca catcccagag gcatctggac aacacaagag
     2281 ctgccacctc ccctggagta gggcagtcag cacctggcac caggaaggag attgtgccca
     2341 agtgcaatgg ctccctagtc aaagtgccta caacacctgc cagcccagtg aaaagctggg
     2401 gaggattccg gattccaaag aagggggaac ggcagcagca aggagaagcc catgatgggg
     2461 cctgccacca gcactcagac tgctcccatc tgggtataag ccgagctcca gccaaggaga
     2521 gatcgaagag caggttaaga actgacagtg agaacgatgg ttacgcccct gatggggaaa
     2581 tgagtgactc agaaagcgag gcatcagaga agaaatgtat ccatgccagc agcaccatca
     2641 gcaggaggac agatatcatc aggagaagca tcttggcctc ttgatgaaac agccggtgtg
     2701 gaagcatatg ttgccatgtg ctgaggagag ctctgatatg ggggcaagca aaaacccatt
     2761 gtttctgagc tccacaaaca gattttcttg caattcagat tgaatttttt ttccagtcat
     2821 ttataaatca ttgtgagaag tttgtgttat ttgcaacttg ttgaggaaac agaagagtag
     2881 attgtaacca taagacacta agattagaac ctgaactaaa cactaagaaa acaaatgaag
     2941 taactttaca gagggggcca ggcttgaata gtattattgc cctctacatt ttccccaaag
     3001 cacaaactct tgaatactct agcagaatca tagaattctg tgtagtgaat aagtcctatt
     3061 tatagaagcc ctcatgtacc atttatagcc cacagagctt attttctagg aatggtaaat
     3121 gctgacagca tttggctccc aggctgtgtg gttgtgagta gctgaggctc agaaacttga
     3181 gcaacactgg gatcttgcac atgtggcatc caggggaaga gtttacacaa caggcactgc
     3241 tggaaggctg gaggagcaga gctgctgcag tgagatttag ggcttgtgta gcgaggtcct
     3301 gaagccctga gtgggctgtg gacataggac gggtagagaa aaagttgtca agaaagtttt
     3361 gtgagaaagg gcagctgagg cccaggtgtt attagtccgc ttgaccttcc tctttcctaa
     3421 ctgctggcct ttggacccaa atgggattcc cctggctact gccagtactt agccatctgg
     3481 cttccaataa tacagtggtt attcgagttc aagtgatgaa cttcagactt tggtgactct
     3541 cactctgcag agtcaaccac tagtacatat ttgggaaatc caggcttcca ccatgagtgg
     3601 attccttaag caaaaggaaa aaaagaagca aaacaggtta tattttaaaa catagaaagg
     3661 caataagttg catcaaggtt atacaggaaa gaagtcaaaa tgtatccttg aataggtttc
     3721 tggagttgga ataggtttct aaactcttga tttgtaactt ggactttcga attgcatatg
     3781 gcaataatta gtaagttatc agcaataata aatttagcat taaatttgag tataatgttc
     3841 tgtttttgca ctcctcatat agtgcatatg tattcagaca agtggatagt gttaaagtcc
     3901 tgttattttc tttggaattc aatgtagttg tgaatcaaat ttaagagaag gcaagtttca
     3961 gtagcaatga gatttagaat taagggcatt tggagtaagc ccggtttccc cgaaattacc
     4021 cttagtttat taatatcaat gttcagattc ctgattcatt tatacatctg tttccatgtg
     4081 gcagggacat tctgataatt aatgagcaat gttttgaatt tgtagaagct ttcaagtctt
     4141 ccagatgatc gtcaacaaca gaaaaggctt attgaattcc atcttgctat gcaagtttta
     4201 tcagatgatc aaatgacaga tctgatgcat ctcattgtat gtatgacatt ttcaaaccaa
     4261 gtcttaactt ctcaagtaca ttgtagtagc taattcaggg gaggggaaag gatgacccag
     4321 gttttagatt gactattttt tgagctatgg agctcctttg agactgctgt ccagatcagc
     4381 ttgttgctac cagtattaga agatttttag gagtccaagt tgtacttttg cttgtagcct
     4441 aatttaaaaa tgagatgttt tgcatatgag caaaaccctt gtgctggata caggaaaagg
     4501 ctggaccctt atctagttat cttttgataa cagcaacagc tctggtgaga taggatttat
     4561 agagggataa cctgtgaagc catagaaaga aaacctaaat tgatttagtg agtgtacggc
     4621 ctctcaccat tttaggaggc accagattca tttgcactat taggaatgct agttttgtgc
     4681 aaaaataatg ccttacctgt tttcccccac atttaggttg aaaagctttc aaatgttcca
     4741 agttatgctg aaccaaaaac aaaacaaaac aaaacaaaac aaaaaaaacc caacaaaata
     4801 gtaaaaaaaa aaaataaaaa aaaatttccc ccacaaaaac taaataaaaa aaaataaagc
     4861 ccacatgttt aattactgct ttgaaatgca aatggtctag agcacggttt ctgacagtgt
     4921 aatgatagct ttgtaagtta gtttcatgtc atgctgggaa ctctgtatga ggtggccaca
     4981 agcagccaca gtccacctac ccacttgcat tctattagta ttgagctttt ttgtttgttt
     5041 gttcttttga atcttccttg tgcatcctga ccaagaaata tctttgatta tgatcaatgt
     5101 attatgtcaa aatgtaggct agttgaactt ttgtaaagtt gcctggaatg tcatttgtta
     5161 ggttataaac aaaaatttaa atgaagggtt ttatgtgttg tgtacaaatc ttaattattt
     5221 taaaatggac agactcgtca ttacatttgt aaccttgtac agaggatttt tcactatgtg
     5281 cctagcttgg tgtccattca actaaaattg aaaaaaaaaa ggtgcatgaa gagttaaaat
     5341 cagaagttaa acaaagtcta tgtagagatg actattttat attacatggc ccaatcctgt
     5401 atttatttct atcccctttt tgaaagtatt tataaaacta gttgaagaca gctgtatttt
     5461 tttgttgaac tatttagtag aatttgtgcc tttttgtctg tatgtgaata aatgctgtac
     5521 attttgcaat aca
//
