LOCUS       NM_013138               8803 bp    mRNA    linear   ROD 07-FEB-2025
DEFINITION  Rattus norvegicus inositol 1,4,5-trisphosphate receptor, type 3
            (Itpr3), mRNA.
ACCESSION   NM_013138
VERSION     NM_013138.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 8803)
  AUTHORS   Varshney,S., Adela,R., Kachhawa,G., Dada,R., Kulshreshtha,V.,
            Kumari,R., Agarwal,R. and Khadgawat,R.
  TITLE     Disrupted placental vitamin D metabolism and calcium signaling in
            gestational diabetes and pre-eclampsia patients
  JOURNAL   Endocrine 80 (1), 191-200 (2023)
   PUBMED   36477942
REFERENCE   2  (bases 1 to 8803)
  AUTHORS   Jia,C. and Hegg,C.C.
  TITLE     Effect of IP3R3 and NPY on age-related declines in olfactory stem
            cell proliferation
  JOURNAL   Neurobiol Aging 36 (2), 1045-1056 (2015)
   PUBMED   25482245
  REMARK    GeneRIF: An age-related decline in IP3R3 expression and NPY
            signaling underlie age-related homeostatic changes and olfactory
            dysfunction.
REFERENCE   3  (bases 1 to 8803)
  AUTHORS   Bansaghi,S., Golenar,T., Madesh,M., Csordas,G., RamachandraRao,S.,
            Sharma,K., Yule,D.I., Joseph,S.K. and Hajnoczky,G.
  TITLE     Isoform- and species-specific control of inositol
            1,4,5-trisphosphate (IP3) receptors by reactive oxygen species
  JOURNAL   J Biol Chem 289 (12), 8170-8181 (2014)
   PUBMED   24469450
  REMARK    GeneRIF: Physiologically relevant reactive oxygen species controls
            cytoplasmic and mitochondrial calcium transport through IP3R3.
REFERENCE   4  (bases 1 to 8803)
  AUTHORS   Zeng,Z., Zhang,H., Lin,N., Kang,M., Zheng,Y., Li,C., Xu,P., Wu,Y.
            and Luo,D.
  TITLE     Role of inositol-1,4,5-trisphosphate receptor in the regulation of
            calcium transients in neonatal rat ventricular myocytes
  JOURNAL   J Pharmacol Sci 126 (1), 37-46 (2014)
   PUBMED   25242084
  REMARK    GeneRIF: It regulates calcium transients in neonatal rat
            ventricular myocytes.(37-46)
REFERENCE   5  (bases 1 to 8803)
  AUTHORS   Schulman,J.J., Wright,F.A., Kaufmann,T. and Wojcikiewicz,R.J.H.
  TITLE     The Bcl-2 protein family member Bok binds to the coupling domain of
            inositol 1,4,5-trisphosphate receptors and protects them from
            proteolytic cleavage
  JOURNAL   J Biol Chem 288 (35), 25340-25349 (2013)
   PUBMED   23884412
REFERENCE   6  (bases 1 to 8803)
  AUTHORS   Mak,D.O., McBride,S., Raghuram,V., Yue,Y., Joseph,S.K. and
            Foskett,J.K.
  TITLE     Single-channel properties in endoplasmic reticulum membrane of
            recombinant type 3 inositol trisphosphate receptor
  JOURNAL   J Gen Physiol 115 (3), 241-256 (2000)
   PUBMED   10694253
REFERENCE   7  (bases 1 to 8803)
  AUTHORS   Sharp,A.H., Nucifora,F.C. Jr., Blondel,O., Sheppard,C.A., Zhang,C.,
            Snyder,S.H., Russell,J.T., Ryugo,D.K. and Ross,C.A.
  TITLE     Differential cellular expression of isoforms of inositol
            1,4,5-triphosphate receptors in neurons and glia in brain
  JOURNAL   J Comp Neurol 406 (2), 207-220 (1999)
   PUBMED   10096607
REFERENCE   8  (bases 1 to 8803)
  AUTHORS   Lee,B., Bradford,P.G. and Laychock,S.G.
  TITLE     Characterization of inositol 1,4,5-trisphosphate receptor isoform
            mRNA expression and regulation in rat pancreatic islets, RINm5F
            cells and betaHC9 cells
  JOURNAL   J Mol Endocrinol 21 (1), 31-39 (1998)
   PUBMED   9723861
REFERENCE   9  (bases 1 to 8803)
  AUTHORS   Maranto,A.R.
  TITLE     Primary structure, ligand binding, and localization of the human
            type 3 inositol 1,4,5-trisphosphate receptor expressed in
            intestinal epithelium
  JOURNAL   J Biol Chem 269 (2), 1222-1230 (1994)
   PUBMED   8288584
REFERENCE   10 (bases 1 to 8803)
  AUTHORS   Blondel,O., Takeda,J., Janssen,H., Seino,S. and Bell,G.I.
  TITLE     Sequence and functional characterization of a third inositol
            trisphosphate receptor subtype, IP3R-3, expressed in pancreatic
            islets, kidney, gastrointestinal tract, and other tissues
  JOURNAL   J Biol Chem 268 (15), 11356-11363 (1993)
   PUBMED   8388391
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000020.1.
            
            On Nov 30, 2020 this sequence version replaced NM_013138.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: L06096.1, GQ233031.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-224               JAXUCZ010000020.1  5138812-5139035
            225-295             JAXUCZ010000020.1  5153522-5153592
            296-417             JAXUCZ010000020.1  5164221-5164342
            418-504             JAXUCZ010000020.1  5165619-5165705
            505-663             JAXUCZ010000020.1  5167634-5167792
            664-762             JAXUCZ010000020.1  5167950-5168048
            763-846             JAXUCZ010000020.1  5168310-5168393
            847-993             JAXUCZ010000020.1  5170101-5170247
            994-1089            JAXUCZ010000020.1  5170411-5170506
            1090-1140           JAXUCZ010000020.1  5170740-5170790
            1141-1283           JAXUCZ010000020.1  5170981-5171123
            1284-1383           JAXUCZ010000020.1  5172325-5172424
            1384-1544           JAXUCZ010000020.1  5172525-5172685
            1545-1686           JAXUCZ010000020.1  5173240-5173381
            1687-1848           JAXUCZ010000020.1  5174078-5174239
            1849-2021           JAXUCZ010000020.1  5176081-5176253
            2022-2141           JAXUCZ010000020.1  5176770-5176889
            2142-2324           JAXUCZ010000020.1  5177207-5177389
            2325-2576           JAXUCZ010000020.1  5179032-5179283
            2577-2721           JAXUCZ010000020.1  5179373-5179517
            2722-2863           JAXUCZ010000020.1  5179997-5180138
            2864-3063           JAXUCZ010000020.1  5180512-5180711
            3064-3193           JAXUCZ010000020.1  5183154-5183283
            3194-3251           JAXUCZ010000020.1  5183625-5183682
            3252-3417           JAXUCZ010000020.1  5184925-5185090
            3418-3582           JAXUCZ010000020.1  5185894-5186058
            3583-3657           JAXUCZ010000020.1  5186136-5186210
            3658-3783           JAXUCZ010000020.1  5186658-5186783
            3784-3906           JAXUCZ010000020.1  5187952-5188074
            3907-4107           JAXUCZ010000020.1  5188506-5188706
            4108-4359           JAXUCZ010000020.1  5189469-5189720
            4360-4485           JAXUCZ010000020.1  5189871-5189996
            4486-4611           JAXUCZ010000020.1  5190081-5190206
            4612-4732           JAXUCZ010000020.1  5192400-5192520
            4733-4923           JAXUCZ010000020.1  5192813-5193003
            4924-5072           JAXUCZ010000020.1  5193159-5193307
            5073-5181           JAXUCZ010000020.1  5193425-5193533
            5182-5272           JAXUCZ010000020.1  5193617-5193707
            5273-5442           JAXUCZ010000020.1  5193868-5194037
            5443-5617           JAXUCZ010000020.1  5195742-5195916
            5618-5799           JAXUCZ010000020.1  5196008-5196189
            5800-6000           JAXUCZ010000020.1  5196332-5196532
            6001-6111           JAXUCZ010000020.1  5196657-5196767
            6112-6207           JAXUCZ010000020.1  5197122-5197217
            6208-6309           JAXUCZ010000020.1  5197312-5197413
            6310-6396           JAXUCZ010000020.1  5197499-5197585
            6397-6507           JAXUCZ010000020.1  5197981-5198091
            6508-6700           JAXUCZ010000020.1  5198174-5198366
            6701-6826           JAXUCZ010000020.1  5198455-5198580
            6827-6999           JAXUCZ010000020.1  5198907-5199079
            7000-7164           JAXUCZ010000020.1  5199493-5199657
            7165-7357           JAXUCZ010000020.1  5200021-5200213
            7358-7462           JAXUCZ010000020.1  5200646-5200750
            7463-7590           JAXUCZ010000020.1  5200839-5200966
            7591-7756           JAXUCZ010000020.1  5201368-5201533
            7757-7917           JAXUCZ010000020.1  5201970-5202130
            7918-8079           JAXUCZ010000020.1  5202995-5203156
            8080-8803           JAXUCZ010000020.1  5203461-5204184
FEATURES             Location/Qualifiers
     source          1..8803
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..8803
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /note="inositol 1,4,5-trisphosphate receptor, type 3"
                     /db_xref="GeneID:25679"
                     /db_xref="RGD:2934"
     exon            1..224
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     CDS             136..8148
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /note="insP3R3; type 3 InsP3 receptor; IP3 receptor; type
                     3 inositol 1,4,5-trisphosphate receptor; IP3R 3; inositol
                     1,4,5-triphosphate receptor 3; inositol 1,4,5-triphosphate
                     receptor, type 3"
                     /codon_start=1
                     /product="inositol 1,4,5-trisphosphate-gated calcium
                     channel ITPR3"
                     /protein_id="NP_037270.2"
                     /db_xref="GeneID:25679"
                     /db_xref="RGD:2934"
                     /translation="MNEMSSFLHIGDIVSLYAEGSVNGFISTLGLVDDRCVVEPAAGD
                     LDNPPKKFRDCLFKVCPMNRYSAQKQYWKAKQTKQDKEKIADVVLLQKLQHAAQMEQK
                     QNDTENKKVHGDVVKYGSVIQLLHMKSNKYLTVNKRLPALLEKNAMRVTLDATGNEGS
                     WLFIQPFWKLRSNGDNVVVGDKVILNPVNAGQPLHASNYELSDNVGCKEVNSVNCNTS
                     WKINLFMQFRDHLEEVLKGGDVVRLFHAEQEKFLTCDEYRGKLQVFLRTTLRQSATSA
                     TSSNALWEVEVVHHDPCRGGAGHWNGLYRFKHLATGNYLAAEENPSYKGDVSDPKAAG
                     PGAQSRTGRRNAGEKIKYRLVAVPHGNDIASLFELDPTTLQKTDSFVPRNSYVRLRHL
                     CTNTWIQSTNAPIDVEEERPIRLMLGTCPTKEDKEAFAIVSVPVSEIRDLDFANDASS
                     MLASAVEKLNEGFISQNDRRFVIQLLEDLVFFVSDVPNNGQNVLDIMVTKPNRERQKL
                     MREQNILKQIFGILKAPFRDKGGEGPLVRLEELSDQKNAPYQYMFRLCYRVLRHSQED
                     YRKNQEHIAKQFGMMQSQIGYDILAEDTITALLHNNRKLLEKHITKTEVETFVSLVRK
                     NREPRFLDYLSDLCVSNRIAIPVTQELICKCVLDPKNSDILIQTELRPVKEMAQSHEY
                     LSIEYSEEEVWLTWTDRNNEHHEKSVRQLAQEARAGNAHDENVLSYYRYQLKLFARMC
                     LDRQYLAIDEISKQLGVELLFLCMADEMLPFDLRASFCHLMLHVHVDRDPQELVTPVK
                     FARLWTEIPTAITIKDYDSNLNASRDDKKNKFASTMEFVEDYLNNVVGEAVPFANDEK
                     NILTFEVVSLAHNLIYFGFYSFSELLRLTRTLLGIIDCIQAPAAVLQAYEEPGGKNVR
                     RSIQGVGHMMSTMVLSRKQSVFGASSLPTGVGVPEQLDRSKFEDNEHTVVMETKLKIL
                     EILQFILNVRLDYRISYLLSVFKKEFVEVFPMQDSGADGTAPAFDSSTANMNLDRIGE
                     QAEAMFGVGKTSSMLEVDDEGGRMFLRVLLHLTMHDYPPLVSGALQLLFKHFSQRQEA
                     MHTFKQVQLLISAQDVENYKVIKSELDRLRTMVEKSELWVDKKGSVKGEEGEAGASKD
                     KKERPSDEEGFLQPHGEKSSENYQIVKGILERLNKMCGVGEQMRKKQQRLLKNMDAHK
                     VMLDLLQIPYDKNDNKMMEILRYTHQFLQKFCAGNPGNQALLHKHLQLFLTPGLLEAE
                     TMQHIFLNNYQLCSEISEPVLQHFVHLLATHGRHVQYLDFLHTVIKAEGKYVKKCQDM
                     IMTELTNAGDDVVVFYNDKASLAHLLDMMKAARDGVEDHSPLMYHISLVDLLAACAEG
                     KNVYTEIKCTSLLPLEDVVSVVTHEDCITEVKMAYVNFVNHCYVDTEVEMKEIYTSNH
                     IWTLFENFTLDMALVCNKREKRLSDPTLEKYVLTVVLDTISAFFSSPFSENSTSLQTH
                     QTIVVQLLQSTTRLLECPWLQQQHKGSVEACVRTLAMVAKSRAILLPMDLDAHMSALL
                     SSGGSCSAAAQRSAANYKTATRTFPRVIPTANQWDYKNIIEKLQDIITALEERLKPLV
                     QAELSVLVDMLHWPELLFLEGSEAYQRCESGGFLSKLIRHTKGLMESEEKLCVKVLRT
                     LQQMLQKKSKYGDRGNQLRKMLLQNYLQNRKSGPRGELTDPTGSGVDQDWSAIAATQC
                     RLDKEGATKLVCDLITSTKNEKIFQESIGLAIRLLDGGNTEIQKSFYNLMTSDKKSER
                     FFKVLHDRMKRAQQETKSTVAVNMSDLGSQPREDREPADPTTKGRVSSFSMPSSSRYS
                     LGPGLHRGHDVSERAQNNEMGTSVLIMRPILRFLQLLCENHNRDLQNFLRCQNNKTNY
                     NLVCETLQFLDIMCGSTTGGLGLLGLYINEDNVGLVIQTLETLTEYCQGPCHENQTCI
                     VTHESNGIDIITALILNDISPLCKYRMDLVLQLKDNASKLLLALMESRHDSENAERIL
                     ISLRPQELVDVIKKAYLQEEERENSEVSPREVGHNIYILALQLSRHNKQLQHLLKPVK
                     RIQEEEAEGISSMLSLNNKQLSQMLKSSAPAQEEEEDPLAYYENHTSQIEIVRQDRSM
                     EQIVFPVPAICQFLTEETKHRLFTTTEQDEQGSKVSDFFDQSSFLHNEMEWQRRLRSM
                     PLIYWFSRRMTLWGSISFNLAVFINIIIAFFYPYVEGASTGVLGSPLISLLFWILICF
                     SIAALFTKHYSVRPLIVALVLRSIYYLGIGPTLNILGALNLTNKIVFVVSFVGNRGTF
                     IRGYKAMVMDMEFLYHVGYILTSVLGLFAHELFYSILLFDLIYREETLFNVIKSVTRN
                     GRSILLTALLALILVYLFSIVGFLFLKDDFILEVDRLPGNHSRASTLGMPHGAATFMG
                     TCSGDKMDCVSEVSVPEILEEDEELDSTERACDTLLMCIVTVMNHGLRNGGGVGDILR
                     KPSKDESLFPARVVYDLLFFFIVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCF
                     ICGLERDKFDNKTVSFEEHIKLEHNMWNYLYFIVLVRVKNKTDYTGPESYVAQMIKNK
                     NLDWFPRMRAMSLVSGEGEGEQNEIRILQEKLGSTMKLVSHLTAQLNELKEQMTEQRK
                     RRQRLGFVDVQNCMSR"
     exon            225..295
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            296..417
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            418..504
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            505..663
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            664..762
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            763..846
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            847..993
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            994..1089
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            1090..1140
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            1141..1283
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            1284..1383
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            1384..1544
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            1545..1686
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            1687..1848
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            1849..2021
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            2022..2141
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            2142..2324
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            2325..2576
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            2577..2721
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            2722..2863
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            2864..3063
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            3064..3193
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            3194..3251
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            3252..3417
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            3418..3582
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            3583..3657
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            3658..3783
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            3784..3906
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            3907..4107
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            4108..4359
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            4360..4485
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            4486..4611
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            4612..4732
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            4733..4923
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            4924..5072
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            5073..5181
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            5182..5272
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            5273..5442
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            5443..5617
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            5618..5799
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            5800..6000
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            6001..6111
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            6112..6207
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            6208..6309
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            6310..6396
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            6397..6507
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            6508..6700
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            6701..6826
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            6827..6999
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            7000..7164
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            7165..7357
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            7358..7462
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            7463..7590
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            7591..7756
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            7757..7917
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            7918..8079
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
     exon            8080..8803
                     /gene="Itpr3"
                     /gene_synonym="IP3R-3; IP3R3; IP3R3X"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccggatcgtc caagtcgccg ggctgcgagg tggcactgcg ctcctttccg cccagcgcgc
       61 ctcagtcctc tgcaccgagc ctggcagctc gcttctgggc gactttgccg cctcgagccc
      121 cggagggcca aagccatgaa tgaaatgtcc agctttcttc acatcgggga cattgtgtcc
      181 ctgtacgccg agggctctgt caacggcttc atcagcactt tggggctggt ggatgaccgt
      241 tgtgtggtgg agcctgcagc tggggacctg gacaaccccc ccaagaagtt ccgagattgc
      301 ctcttcaaag tgtgccccat gaaccgctac tccgcacaga agcagtactg gaaagccaag
      361 cagactaagc aggacaaaga gaagatcgcc gatgtggtgt tgctgcagaa gctgcagcat
      421 gcagcccaga tggagcagaa gcaaaacgac acagagaaca agaaggtgca cggggacgtg
      481 gtgaagtacg gcagcgtgat tcagcttctg cacatgaaga gcaacaaata cttaacggtg
      541 aacaagcggc tgccggccct gctggagaag aacgccatgc gggtgacgct ggacgcgaca
      601 ggcaacgagg gctcctggct cttcatccag cccttctgga agcttcggag caatggggat
      661 aacgtggttg tgggggacaa ggtgatcctg aaccctgtca acgcagggca gcctctacac
      721 gccagcaact atgagcttag tgataacgtt ggctgcaagg aggtcaactc tgtcaactgc
      781 aacaccagct ggaagatcaa cttattcatg cagttccggg accatctgga ggaggtgttg
      841 aaggggggag acgtggtgcg gctgttccat gcagagcagg agaagttcct gacctgtgac
      901 gagtaccggg gcaagcttca ggtgttcctg aggaccacgc tgcgtcagtc cgccacctcg
      961 gccaccagct ccaacgcgct ctgggaggtg gaggtggtcc accatgaccc ctgccgcggc
     1021 ggagcgggac actggaatgg tctgtacagg ttcaagcacc tggccacggg caactatctg
     1081 gcggctgaag aaaaccccag ctacaagggt gatgtctcag atcctaaggc agcaggacca
     1141 ggggcccaga gccgcacagg ccgcagaaac gccggcgaga agatcaagta ccgtctggtg
     1201 gctgtgccac atggcaacga catcgcgtct ctcttcgagc tggaccccac cacgctgcag
     1261 aaaaccgact ccttcgtgcc ccggaactcc tacgtgcggc tgcggcacct ctgtaccaac
     1321 acctggatcc agagcacgaa cgcgcccatc gacgtggagg aggaacggcc tatccggctc
     1381 atgttgggca cgtgccccac caaggaggac aaggaggcct ttgccattgt gtcggttccc
     1441 gtgtctgaga tccgcgacct ggactttgcc aacgatgcaa gctccatgct ggccagcgct
     1501 gtggagaaac tcaacgaggg cttcatcagc cagaacgacc gcaggtttgt catccagctg
     1561 ttggaggact tggtgttttt tgtcagcgat gttcccaaca atgggcagaa tgtcctggac
     1621 atcatggtca ccaaacccaa ccgagagcgg cagaagctga tgcgggagca gaacatactt
     1681 aagcagatct ttggcatcct gaaggctcca ttccgtgaca aggggggtga agggccattg
     1741 gtgcgtctgg aggaactgtc tgaccagaag aacgccccct accagtacat gttccgcctg
     1801 tgttaccggg tgctgcggca ctcccaggag gactaccgta agaaccagga gcacatagcc
     1861 aagcagttcg ggatgatgca gtcacagatt ggctatgaca tcctggccga agacaccatc
     1921 acggccctgc tgcacaacaa ccggaagctg ctggagaagc acatcaccaa gaccgaggtg
     1981 gaaaccttcg tgagcctcgt gcgcaagaac agggagccca ggttcctgga ctacctctcc
     2041 gacctgtgcg tgtccaaccg cattgccatc cccgtcaccc aggagctgat ttgcaagtgt
     2101 gtgctggacc ccaagaacag tgacatcctt atccagactg agcttcggcc cgtgaaggag
     2161 atggctcagt ctcacgagta cctcagcatc gagtactcgg aggaggaggt gtggctcaca
     2221 tggacggaca ggaacaacga gcatcacgag aagagtgtga ggcagctggc ccaggaggca
     2281 agggccggca acgcacacga cgagaacgtg ctcagctact acaggtacca gttgaagctg
     2341 tttgcccgca tgtgcctaga ccgccagtac ctggccatcg acgagatctc caagcaactg
     2401 ggtgtggagc tgcttttcct atgcatggcg gacgagatgc tgccctttga cctccgcgcc
     2461 tcattctgcc acctgatgct acatgtgcac gtggaccgtg acccccagga gctggtgacc
     2521 cctgtcaagt ttgcccgcct ctggacagag atccccacgg ccatcaccat caaagactat
     2581 gattccaatc tcaacgcctc ccgagatgac aagaaaaaca agtttgccag caccatggag
     2641 ttcgtggagg attaccttaa caacgtggtc ggcgaggccg tgccctttgc caacgatgag
     2701 aagaacatac tgacctttga ggtggtcagc ctggcacaca acctcatcta cttcgggttc
     2761 tacagcttca gcgagctgct gcgactcaca cgcacgttgc tgggcatcat cgactgcatt
     2821 caggcaccag ccgctgtgct gcaggcctat gaggagcctg gcggcaagaa cgtgcggagg
     2881 tccatccagg gggtgggaca catgatgtcc accatggtgc taagccgcaa gcagtctgta
     2941 tttggtgcct ccagcctgcc tactggagtg ggtgtccccg agcagctgga cagaagcaaa
     3001 tttgaggaca atgaacacac cgtggtgatg gagaccaagc tgaagatcct ggagatcctg
     3061 cagttcatcc tcaacgtgcg cctagactac cgcatctcct acctgctgtc ggtcttcaag
     3121 aaggagtttg tggaggtctt tcccatgcag gacagcgggg cagacggcac agcccccgcc
     3181 ttcgattcct ctactgccaa catgaatctg gaccgcatcg gggagcaggc agaggccatg
     3241 tttggagtag ggaagaccag cagcatgcta gaggtggatg acgaaggggg tcgcatgttc
     3301 ctgcgagtgc tgctgcacct caccatgcac gactacccac ctctggtctc cggcgccctg
     3361 cagctgctct tcaaacattt cagccagcgc caggaggcca tgcacacctt caagcaggtg
     3421 cagctgctca tctcagccca ggatgtggag aactacaaag tgatcaagtc ggaactggat
     3481 cgactgcgga cgatggtgga gaagtcggag ctgtgggtgg acaagaaagg cagcgtcaag
     3541 ggcgaggagg gggaggcggg cgccagcaag gataagaagg agcggccctc ggatgaggag
     3601 ggatttctgc agccacacgg ggagaagagc agtgagaact accagattgt caaaggcatc
     3661 ctggagaggc tgaacaagat gtgtggggtc ggggagcaga tgcgaaagaa gcaacagaga
     3721 ctgctgaaga acatggacgc ccacaaggtc atgctggacc tgctgcagat cccttatgac
     3781 aagaacgaca acaagatgat ggagatcctg cgctacacac accagttcct acagaagttc
     3841 tgtgccggga accctggcaa ccaggccctt ctgcacaagc acttgcagct cttcctcacg
     3901 cccgggctcc tggaggctga gaccatgcag cacattttcc tcaacaacta tcagctgtgc
     3961 tctgagatca gcgagccggt gctgcaacac ttcgtgcacc tgctggccac acacgggcgc
     4021 cacgtgcagt acctggactt cctgcatact gtcatcaagg ccgagggcaa gtacgtgaag
     4081 aagtgtcagg acatgatcat gaccgagctg accaacgcag gcgacgacgt ggtggtgttc
     4141 tacaatgaca aggcctctct ggcccatctg ctggacatga tgaaggcagc ccgagatggc
     4201 gtggaggacc acagccccct catgtaccac atctccctgg tggacttgct ggctgcctgt
     4261 gcagaaggca aaaatgtcta cacagagatc aagtgcactt ccctgctgcc tctagaggac
     4321 gtggtgtcgg tggtgaccca cgaggactgc atcacggagg ttaaaatggc gtatgtgaac
     4381 ttcgtgaacc actgctatgt agacacggag gtggagatga aggagatcta taccagcaac
     4441 cacatctgga cgctcttcga gaacttcacc ctggacatgg ctctggtctg taacaagcgg
     4501 gagaagcgcc tgtcagaccc cacccttgag aagtacgtgc tcaccgtggt gctggacacc
     4561 atcagcgcct tcttcagttc cccattttca gagaacagca catccctaca gacgcatcag
     4621 acaattgtgg ttcagctgct gcagtccacc acccggctgc tcgagtgtcc ttggctgcag
     4681 cagcagcaca agggctcggt ggaggcctgt gtccgcaccc tcgccatggt ggccaagagt
     4741 agagccatct tgctgccgat ggatctggat gcccacatga gcgctctgct cagcagtggg
     4801 ggcagctgct cagccgcggc ccaacgcagc gctgccaact acaagacggc cacgaggacc
     4861 ttccctcggg tcatccccac cgccaaccag tgggactaca agaacatcat tgagaagtta
     4921 caggacatca tcacggccct agaagagcgg ctgaagcctc tggtgcaggc cgagctctcg
     4981 gtgctggtgg acatgctgca ctggcccgag ctgctctttc tagagggcag tgaggcctac
     5041 cagcgctgcg agagtggcgg cttcctgtcc aagctcatcc gtcacaccaa gggtctcatg
     5101 gagtcggagg agaagctgtg cgtgaaggtg ctgcggacgc tgcagcagat gctgcagaag
     5161 aagagcaagt atggggaccg gggcaaccag ctaaggaaga tgctgctgca gaattacctc
     5221 cagaaccgga agtccggtcc ccggggcgag ctcactgacc ccacaggctc tggcgtggat
     5281 caggactggt ccgccatcgc agccacccag tgccggctgg acaaggaggg ggccaccaag
     5341 ttggtgtgtg atctcatcac cagcaccaag aacgagaaga tcttccagga gagcatcggc
     5401 ctggccatcc gcctgctgga cgggggcaac actgagatcc agaagtcttt ctacaacctg
     5461 atgacaagtg acaagaagtc agagcgcttc ttcaaagtgc tgcatgaccg catgaagcgt
     5521 gcccagcagg agaccaagtc cacagttgcc gtcaacatga gtgacctggg cagccagcct
     5581 cgtgaggacc gtgagccagc agaccctacc accaaaggtc gcgtgtcctc cttctccatg
     5641 cccagctcct cccgatattc gctgggccct ggcttgcacc gggggcacga cgtgagcgag
     5701 cgtgcgcaga acaacgagat ggggacctcg gtgctcatca tgcggcccat cctgcgcttc
     5761 ctgcagctgc tgtgtgagaa ccataaccgg gacctgcaga acttcctgcg ctgtcagaac
     5821 aacaagacca actacaacct cgtgtgtgag accctgcagt tcctggacat catgtgtggc
     5881 agcaccacag ggggcctggg gctgctgggg ctctacatca acgaggacaa tgtgggcctg
     5941 gtcatccaga ccttggagac cctcacagag tactgccagg gcccgtgcca tgagaaccag
     6001 acctgcatcg tgactcacga gtccaacggc attgacatca tcacggcgct gatcctcaat
     6061 gacatcagcc cgctctgcaa gtaccgcatg gacctggtgc tgcagctcaa ggacaatgcc
     6121 tccaagctgc tcctggctct gatggagagt cgacatgaca gcgagaatgc agaacgcatc
     6181 ctcatcagcc ttcggcctca ggagctggtg gacgtgatca agaaggccta cctgcaggag
     6241 gaggagcggg aaaattccga agtgagccca cgtgaagtgg gccacaacat ctacatcctg
     6301 gcactgcagc tttccaggca caacaagcag ctacagcacc tgctgaagcc ggtgaagcgc
     6361 atccaggagg aggaggccga gggcatctct tccatgctca gcctcaacaa caagcagctc
     6421 tctcagatgc tcaagtcctc agcccctgcc caagaggagg aggaagaccc gctggcctac
     6481 tatgagaacc acacctcgca gattgagatt gtgcggcaag accgaagcat ggagcagatc
     6541 gtgttcccgg tacctgccat ctgccagttc ctgacagagg agaccaagca ccggctcttc
     6601 accaccacgg agcaggacga gcagggcagc aaagtgagcg acttcttcga ccagtcctcc
     6661 ttcctgcaca acgagatgga gtggcagcgc cggcttcgca gcatgccgct catctactgg
     6721 ttctcccgcc gcatgacgct gtggggtagc atctccttca acctggcagt gttcatcaac
     6781 atcatcattg ccttcttcta cccctacgtg gaaggcgcgt ccacgggcgt gctgggctcc
     6841 ccactcatct cgctcctctt ctggatcctc atctgcttct ccattgccgc gctgttcacc
     6901 aagcactaca gcgtccgtcc cctcattgtg gcactggtcc ttcgctccat ctactacctg
     6961 ggcattgggc ccacgctcaa catcctgggt gctctcaatc tgaccaacaa gatcgtgttt
     7021 gtggtgagct tcgtgggcaa ccgcggcacc ttcatccgtg gctataaagc aatggtcatg
     7081 gacatggagt tcctgtatca cgtgggctac atcctgacga gtgtcctggg cctctttgct
     7141 catgagctct tctacagtat cctgctcttt gacctcatct accgagagga gacgctgttt
     7201 aatgtcatca agagcgtgac ccgcaatggc cgctccatcc tgctaactgc cctgctggcc
     7261 ctcatccttg tctacctctt ctccatcgtg ggcttcctct tcctcaagga tgacttcatc
     7321 ctggaggtgg accggctgcc tgggaaccac tccagagcca gcaccctggg gatgccacac
     7381 ggagctgcca catttatggg cacatgtagt ggggacaaga tggactgtgt ctctgaggtc
     7441 tcggtgcctg agatcctaga agaggacgag gagctggaca gcacagagcg ggcctgtgat
     7501 actctgctta tgtgtattgt caccgtcatg aaccacggac tgaggaacgg tggcggcgtg
     7561 ggcgacatcc tccgcaagcc ctccaaagac gagtcgctct tcccagccag ggtggtgtac
     7621 gacctcctgt tcttcttcat tgtcatcatt attgtcctga acctcatctt tggggtgatc
     7681 atcgacacct tcgccgacct gcgcagcgag aagcagaaga aagaggaaat cctcaagacc
     7741 acgtgcttca tctgtggtct ggagagggac aagtttgaca acaagacagt gtcctttgaa
     7801 gagcacatca aactggagca caacatgtgg aactacctgt acttcattgt gctggtccgt
     7861 gtcaagaaca agacagacta cacgggcccc gagagctacg tggctcagat gatcaagaac
     7921 aagaacctgg actggttccc acggatgcgc gccatgtcct tggtgagcgg cgagggcgag
     7981 ggcgagcaga acgagatccg catcctgcag gagaagcttg gctccaccat gaagctggtc
     8041 tcgcacctca ccgcccagct caatgagctc aaggaacaga tgacggagca gcggaagcgg
     8101 aggcaacgtc tgggcttcgt ggacgtgcag aactgcatga gccgctgagc agagcggagc
     8161 ctcggaggcc cccacgggag gccggctgcc cacagcgccg cccttccttc aggtcaggta
     8221 gaagccaggt gcctgcccca tcttcagctc agctgccacc ctccctcccc aagccaggct
     8281 ctggccagtg ggagtgccag agcagagcac ggtcctgctt agtaagtacc cttgaagaga
     8341 ctcggtttac cttagtgcct taggggatgc caagtcctcc agactgctgt ccttcgaagc
     8401 agtgactggc attcctcagt ggccctggca ggtggttaaa agtgggctgc ctctcacctc
     8461 caagcactac attgtggctg tcccctgcct gccaccctgg ctcaggaagg tggtagcctg
     8521 ctgttattag cttcctaggg ctttgatatt taacttattc ctgggggcca tcccaccctc
     8581 ctgtgcctgc tggggacagt gtggccccgt cccaggagcc tcatgactca ggatggacct
     8641 tgctcccagg actttctcta ggctttgtag gcaagcctca caagcccagc aacaggcctg
     8701 ggctgtgtga cagtggcttc tctctttttg gtgtaatgtt ttacatgtcc tgtgtcctgg
     8761 agactaatgt gttaattgcc ttaaataaat taatagactc caa
//
