LOCUS       XM_039108427           12494 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus inositol 1,4,5-trisphosphate receptor,
            type 2 (Itpr2), transcript variant X3, mRNA.
ACCESSION   XM_039108427
VERSION     XM_039108427.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051339.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039108427.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12494
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..12494
                     /gene="Itpr2"
                     /note="inositol 1,4,5-trisphosphate receptor, type 2;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 27 ESTs, 2 long SRA reads, 5 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 3 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:81678"
                     /db_xref="RGD:69649"
     CDS             770..9025
                     /gene="Itpr2"
                     /codon_start=1
                     /product="inositol 1,4,5-trisphosphate receptor type 2
                     isoform X2"
                     /protein_id="XP_038964355.1"
                     /db_xref="GeneID:81678"
                     /db_xref="RGD:69649"
                     /translation="MLGTLKAPRRWKSSTGQMLKTHVEEHAPLKVTENFNKSHFDASM
                     WAKAKGSRENKRKLETTSGYMWILPGDLLGKCVPHRRLVDDRCVVHPEAGDLTNPPKK
                     FRDCLFKVCPMNRYSAQKQYWKAKQAKQGNHTEAALLKKLQHAAELEQKQNESENRKL
                     LGEIVKYSNVIQLLHIKSNKYLTVNKRLPALLEKNAMRVSLDAAGNEGSWFYIHPFWK
                     LRSEGDNIVVGDKVVLMPVNAGQPLHASNVELLDNPGCKEVNAVNCNTSWKITLFMKF
                     SSYREDVLKGGDVVRLFHAEQEKFLTCDDYEKKQHIFLRTTLRQSATSATSSKALWEI
                     EVVHHDPCRGGAGQWNSLFRFKHLATGNYLAAELNPDYRDAQNEGKTVRDGELPTSKK
                     KRQAGEKIMYTLVSVPHGNDIASLFELDATTLQRADCLVPRNSYVRLRHLCTNTWVTS
                     TSIPIDTEEERPVMLKIGTCQTKEDKEAFAIVCVPLSEVRDLDFANDANKVLATTVKK
                     LENGSITQNERRFVTKLLEDLIFFVADVTNNGQDVLDVVITKPNRERQKLMREQNILA
                     QVFGILKAPFKEKAGEGSMLRLEDLGDQRYAPYKYVLRLCYRVLRHSQQDYRKNQEYI
                     AKNFCVMQSQIGYDILAEDTITALLHNNRKLLEKHITAKEIETFVSLLRRNREPRFLD
                     YLSDLCVSNSTAIPVTQELICKFMLSPGNADILIQTKLVSMQVENPMESSILPDDIDD
                     EEVWLYWIDSNKEPHGKAIRHLAQEAREGTKADLEVLTYYRYQLNLFARMCLDRQYLA
                     INQISTQLSVDLILRCVSDESLPFDLRASFCRLMLHMHVDRDPQESVVPVRYARLWTE
                     IPTKITIHEYDSITDSSRNDMKRKFALTMEFVEEYLKEVVNQPFPFGDKEKNKLTFEV
                     VHLARNLIYFGFYSFSELLRLTRTLLAILDIVQAPMSSYFERLSKFQDGSNNVMRTIH
                     GVGEMMTQMVLSRGSIFPVSVPDAQPSVHPSKQASPGEQEDVTVMDTKLKVIEILQFI
                     LSVRLDYRISYMLSIYKKEFGENDGNGDPSASGTPETLLPSALVPDIDEIAAQAETMF
                     AGRKEKTPVQLDDEGGRTFLRVLIHLIMHDYAPLLSGALQLLFKHFSQRAEVLQAFKQ
                     VQLLVSNQDVDNYKQIKADLDQLRLTVEKSELWVEKSSSYENGDMGEGQAKGGEEANE
                     ESNLLSPVQDGAKTPQIDSNKGNNYRIVKEILIRLSKLCVQNKKCRNQHQRLLKNMGA
                     HSVVLDLLQIPYEKTDEKMNEVMDLAHTFLQNFCRGNPQNQVLLHKHLNLFLTPGLLE
                     AETMRHIFMNNYHLCNEISERVVQHFVHCIETHGRHVEYLRFLQTIVKADGKYVKKCQ
                     DMVMTELINGGEDVLIFYNDRASFPILLNMMCSERARGDESGPLAYHITLVELLAACT
                     EGKNVYTEIKCNSLLPLDDIVRVVTHDDCIPEVKIAYVNFVNHCYVDTEVEMKEIYTS
                     NHIWKLFENFLVDMARVCNTTTDRKHADTFLERCVTESVMNIVSGFFNSPFSDNSTSL
                     QTHQPVFIQLLQSAFRIYNCTWPNPAQKASVESCIRALAEVAKNRGIAIPVDLDSQVN
                     TLFMKNHSSTVQRAAMGWRLSARSGPRFKEALGGPAWDYRNIIEKLQDVVASLEQQFS
                     PMMQAEFSVLVDVLYSPELLFPEGSDARIRCGAFMSKLINHTKKLMEKEEKLCIKILQ
                     TLREMLEKKDSFMEEGSTLRKILLNRYFKGDHSVGVNGPLSGAYAKTAQVGGGFTGQD
                     ADKTGISMSDIQCLLDKEGASELVIDVIVNTKNDRIFSEGILLGIALLEGGNTQTQNS
                     FYQQLHEQKKSEKFFKVLYDRMKAAQKEIRSTVTVNTIDLGSKKREEDSDLMALGPRM
                     RVRDSSLHLKEGMKGQLTEASSATSKAYCVYRREMDPDIDTMCPGQEAGSAEEKSAEE
                     VTMSPAITIMRPILRFLQLLCENHNRELQNFLRNQNNKTNYNLVCETLQFLDCICGST
                     TGGLGLLGLYINEKNVALVNQTLESLTEYCQGPCHENQTCIATHESNGIDIIIALILS
                     DINPLGKYRMDLVLQLKNNASKLLLAIMESRHDSENAERILFNMRPKELVDVMKNAYN
                     QGLECNHGDEEGGDDGVSPKDVGHNIYILAHQLARHNKLLQQMLKPGSDPEEGDEALK
                     YYANHTAQIEIVRHDRTMEQIVFPVPNICEFLTRESKYRVFNTTERDEQGSKVNDFFQ
                     QTEDLYNEMKWQKKIRNNPALFWFSRHISLWGSISFNLAVFINLAVALFYPFGDDGDE
                     GTLSPLFSALLWVAVAICTSMLFFFSKPVGIRPFLVSIMLRSIYTIGLGPTLILLGAA
                     NLCNKIVFLVSFVGNRGTFTRGYRAVILDMAFLYHVAYVLVCMLGLFVHEFFYSFLLF
                     DLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIIGFLFLKDDFTMEVDRLKN
                     RTPVTGNDGVPTMTLTSMLGTCPKENCSPTIPSSNAAGEGGEDGIERTCDTLLMCIVT
                     VLNQGLRNGGGVGDVLRRPSKDEPLFAARVVYDLLFFFIVIIIVLNLIFGVIIDTFAD
                     LRSEKQKKEEILKTTCFICGLERDKFDNKTVSFEEHIKSEHNMWHYLYFIVLVKVKDP
                     TEYTGPESYVAQMITEKNLDWFPRMRAMSLVSNEGDSEQNEIRNLQEKLESTMSLVKQ
                     LSGQLAELKEQMTEQRKNKQRLGFLGSNTPHVNHHMPPH"
ORIGIN      
        1 gcttatctgt tcttcactct tagtctcttg tcttcttacc gtcttccctc tctgtccctt
       61 ctctcccctc cccctctcca ctctccagat attcatggac ggcctctact actctctttt
      121 ctttctcctc tctcccctcc ccctctctgt gttgttctct acctctactc tctcaactcc
      181 cctccccatg ccctaagtaa actctgtttc atcctgtacc catcctatgg tcggtacctc
      241 agggggaaag gacgcctcag catgggccct tcatcataca tgcctctacc aaacagatcc
      301 ctggcttcct tttctttttc ataaaacaca acagtgtcca ctttatctct acccccacct
      361 ctagagttta caaccctgtt gttcttatct agactacaac aattccccct gtgtactctt
      421 ttttttaaaa aataaccaaa catacattta ttcaagtgtt gtcatcttgt gaagatgtat
      481 tctgatgcct atgttgcttc cattatcaaa gtgcacttgt tctgaacctg tctgggcgtg
      541 gccttggaag tagtctgtga gctgtatcat gagaccatca cctcatgttt gaaatcaggg
      601 tcacctctgt cctgattaca gggccaccgc agtgcactgg gtcatcaaac ctcttgctta
      661 ttgtattgtt atccatctcc atgttttcat gagtgggacc tcctggacgt agggctgatt
      721 gggtcctaca gtcactcaag tttgagttct aagacacttt attgtttgga tgctggggac
      781 attgaaggca ccaaggagat ggaagtcatc aactgggcaa atgctgaaga cacacgtgga
      841 ggagcatgca cccctgaagg ttacagagaa cttcaacaag agccattttg atgcatcaat
      901 gtgggcaaag gcaaaaggtt caagagagaa caagagaaaa ctagagacca caagtggata
      961 tatgtggatc ctcccaggag acctactagg gaaatgtgtt cctcacagaa ggttggtgga
     1021 tgaccgttgt gtggtgcatc cggaggcggg ggatcttacc aacccaccca agaagttcag
     1081 agactgcctc ttcaaggtgt gccccatgaa tcgatactct gcccagaagc agtactggaa
     1141 agccaagcag gcgaagcagg gaaaccacac ggaggctgcc ctgctgaaga agctccagca
     1201 cgccgcagag ctggaacaaa aacagaatga gtcagagaac aggaaacttt tgggagaaat
     1261 tgtgaaatac agcaacgtta tacaactact gcacataaaa agcaacaagt acctcaccgt
     1321 gaacaagagg ttacctgcct tactggagaa gaatgccatg cgtgtgtccc tggatgctgc
     1381 agggaacgaa gggtcctggt tctacatcca tcccttctgg aagctgagaa gcgagggtga
     1441 taatatcgtc gtgggagata aagtcgttct gatgcctgta aatgctgggc agcccctgca
     1501 tgccagcaac gtggagctcc tggacaaccc cggctgcaaa gaggtgaatg ctgttaattg
     1561 caacactagc tggaaaatca ctttattcat gaagttcagc tcctaccgag aggatgtatt
     1621 aaaagggggt gacgttgtga gactgtttca tgcggaacaa gagaagtttc tgacctgtga
     1681 tgactatgag aaaaaacagc acattttcct gcggacgacc ttgcgtcaat cagcaacgtc
     1741 ggccactagc tctaaagcac tctgggagat agaggtggtt caccatgatc catgccgcgg
     1801 aggtgcagga cagtggaaca gcctgttcag gtttaagcat cttgcaactg ggaactactt
     1861 agctgcagag cttaaccctg actatcgaga tgctcaaaat gaaggaaaaa ctgtgagaga
     1921 cggggagctt ccaacctcaa agaaaaaacg ccaggcaggg gagaagatca tgtacacgct
     1981 ggtctcggtc ccgcacggaa atgacatcgc gtcccttttt gaacttgacg ccacaactct
     2041 gcagagagct gactgcctgg ttccgaggaa ctcctacgtg cggttgaggc acctgtgtac
     2101 caacacgtgg gtaacaagca ccagcatccc catagacaca gaggaagaga ggcctgtcat
     2161 gctgaaaatt gggacctgcc agaccaagga agacaaagaa gcctttgcca tcgtgtgcgt
     2221 cccgctgtct gaggtccgag acctggactt tgccaacgat gccaacaaag tattggccac
     2281 cacggtgaag aagctggaga atggcagcat cacccagaat gagaggaggt ttgtgactaa
     2341 gttgttggaa gacctcattt tctttgtggc tgatgtgacc aacaacggac aggatgttct
     2401 ggatgtggtc atcaccaagc ccaaccggga acggcaaaaa ctaatgaggg aacagaatat
     2461 tctggcacag gtgtttggga tccttaaagc ccctttcaag gagaaggctg gggaaggctc
     2521 gatgctgagg ctggaggacc tgggcgacca gcgctatgcc ccgtacaagt acgtgctgcg
     2581 tctctgctac cgcgtgctgc ggcattcgca gcaggactac aggaagaacc aggagtacat
     2641 cgctaagaac ttctgcgtca tgcagtctca gatcggctat gatattttgg cagaagatac
     2701 gatcacagcc ttgctacaca acaaccgcaa actcctggag aaacacatca cggccaaaga
     2761 aatcgagacc ttcgtcagcc tgctcaggag gaaccgggag ccgaggtttc tggactatct
     2821 gtctgacctc tgcgtgtcca atagcaccgc catccctgtg actcaggagc tcatctgcaa
     2881 attcatgctg agccccggca atgcggacat cctcattcag acgaagctgg tgtccatgca
     2941 agtggaaaac cccatggaga gttccatcct tcccgatgac atcgacgacg aggaggtttg
     3001 gctttactgg attgacagca acaaggagcc tcacggcaag gccatcaggc acctggccca
     3061 ggaggccagg gaaggcacca aggctgacct agaagtcctg acctattaca ggtaccagct
     3121 aaacctcttt gcaaggatgt gcttggaccg ccagtacctg gccatcaacc agatttcaac
     3181 acagctgtct gtagacctga tcctgcggtg cgtgtctgac gagagcctgc cctttgacct
     3241 ccgagcctct ttctgccgac tcatgctcca catgcacgtg gaccgggacc cccaggagtc
     3301 tgtggtgcct gtccgctacg cccggctctg gactgagatc cccaccaaga tcacgatcca
     3361 tgagtatgac tccatcacag actcttccag aaatgacatg aagaggaagt ttgccctgac
     3421 aatggaattt gtcgaagaat atttgaaaga agttgtgaat caaccgtttc cttttggaga
     3481 caaagagaaa aataaactga catttgaggt ggtccacctg gcccggaacc tcatctactt
     3541 cggattctac agcttcagcg agttgctgcg gctgacgaga actctgctgg cgatcctgga
     3601 catcgtccag gcccccatgt cgtcgtattt tgaaagatta agcaagtttc aagatggaag
     3661 caacaatgtc atgaggacca tccacggggt gggagagatg atgacacaga tggtgctcag
     3721 cagaggctcc attttcccag tgagcgtgcc cgacgcacag cccagcgtcc accccagcaa
     3781 gcaggcgagc cccggcgagc aggaggatgt gacggttatg gataccaagc taaaggttat
     3841 cgagatttta cagttcatcc tgagtgtcag gctggactac cgtatctctt acatgctgtc
     3901 catatacaag aaggaatttg gggagaatga tggcaacggt gacccctctg ccagcggcac
     3961 cccggaaaca ttgctaccat cagctcttgt ccctgacatt gatgagattg cggctcaggc
     4021 agaaacgatg tttgctggaa gaaaagaaaa aactccagtt cagcttgatg atgagggagg
     4081 cagaaccttc ttaagagtcc tcatccacct gatcatgcat gactatgctc cactgctgtc
     4141 cggggccctg cagctgctgt tcaaacactt cagccagaga gcagaagtgc ttcaggcctt
     4201 caaacaggtg cagttactag tgtcgaacca agatgtcgat aactacaagc aaatcaaggc
     4261 agacctggac caacttcggc tgacggtgga gaagtccgag ctatgggtgg aaaagagcag
     4321 cagctatgag aatggagaca tgggcgaggg ccaggccaaa ggaggcgaag aggcaaatga
     4381 ggagtccaac ctcttgagcc cggtgcagga cggcgcgaag acacctcaga tcgacagcaa
     4441 caagggcaac aactaccgga tcgtcaagga gatcttgatt aggctgagta agctctgtgt
     4501 gcagaacaag aaatgtcgta atcaacacca acggttgctg aaaaatatgg gggctcactc
     4561 cgtggtactg gaccttctgc agatccccta tgagaagacc gacgagaaga tgaacgaggt
     4621 gatggactta gcccacacct tcctgcagaa cttctgccgc gggaatccac agaaccaagt
     4681 tctccttcac aagcatctca acctgttcct aacccctgga ctcctggagg cggaaaccat
     4741 gcggcacatc ttcatgaaca attaccatct gtgcaatgag atcagcgaga gggtggtcca
     4801 gcactttgtg cactgcattg agacacacgg ccgccacgtg gagtacctga ggttcctgca
     4861 gaccatcgtg aaagcagacg gcaaatacgt gaagaaatgc caggacatgg tgatgaccga
     4921 gctgatcaat gggggtgaag acgtactgat attctacaac gaccgagcct catttcccat
     4981 ccttctcaac atgatgtgct ccgagagagc ccgtggggat gagagcggcc ccctggccta
     5041 ccatatcacc cttgtggagt tgctggcagc gtgcactgag gggaagaacg tctacacgga
     5101 gatcaagtgc aattctctct tgcctctgga cgacatagtg agggtggtga cccacgacga
     5161 ctgcattcct gaggtaaaaa ttgcatacgt gaactttgtc aaccattgtt acgttgacac
     5221 agaagtggag atgaaggaaa tctatacaag taaccacatt tggaagttat ttgagaactt
     5281 cttggtggat atggcaaggg tctgcaacac caccacggac cggaaacacg cagacacctt
     5341 tctggagagg tgtgtgacag agtcagtcat gaacatcgtg agcggcttct tcaactcgcc
     5401 gttttcggat aacagtacca gcctccagac ccatcagccg gtctttatcc agctgctgca
     5461 gtccgccttc agaatttaca actgcacctg gcccaaccca gcccagaaag cctccgtgga
     5521 atcctgcatc agagccctgg ctgaagtggc caaaaaccgt gggattgcga ttccggtgga
     5581 tttggacagc caggtcaaca cactcttcat gaagaatcac tcaagtacag tgcagagggc
     5641 ggccatgggc tggaggctct ctgctcgctc cggacctcgc ttcaaggaag ctcttggagg
     5701 gccagcatgg gactacagga atattattga aaagttacag gatgtcgtgg cctctctgga
     5761 acagcagttc agccccatga tgcaggctga gttctctgtg cttgtggatg tgctgtacag
     5821 cccggagcta ctgttcccag aaggaagcga tgccaggata cgatgtggtg ccttcatgtc
     5881 caagctgatt aatcacacaa agaaactgat ggaaaaagaa gaaaaactgt gcattaaaat
     5941 cctccagacg ttacgggaga tgctggagaa gaaagacagc ttcatggaag agggtagcac
     6001 attacggaaa atcctcctga atcggtactt caagggtgac cacagcgttg gtgtgaacgg
     6061 acctctgtca ggagcctacg ccaagacagc acaagtggga gggggcttca ctggacagga
     6121 tgccgataag acggggattt ccatgtccga tatccagtgt ttgctggaca aggaaggggc
     6181 ctccgaactt gtcatcgatg tcattgtgaa caccaaaaac gacaggatct tttccgaggg
     6241 catcttgctt ggcattgccc tgctggaagg aggaaacaca caaacccaga attctttcta
     6301 ccagcagttg catgaacaaa aaaagtcaga gaaattcttc aaagtccttt acgatcggat
     6361 gaaggctgct cagaaagaga tcagatccac ggtgactgtc aacaccatag acttagggag
     6421 caagaagaga gaggaggaca gtgacctcat ggccttgggc cctcggatga gagtgagaga
     6481 ctcatcgctg catttgaaag agggaatgaa agggcagttg actgaggcgt cttcagccac
     6541 gtccaaagca tactgtgtgt acagaaggga aatggaccca gacattgaca caatgtgccc
     6601 gggacaggaa gcaggaagtg cggaggaaaa gtctgcagag gaagttacca tgagcccagc
     6661 catcactatc atgcggccca tcctcaggtt cctgcagtta ctgtgtgaga atcacaaccg
     6721 ggagcttcag aacttcttga ggaaccagaa caacaaaaca aactacaacc ttgtctgtga
     6781 aacacttcag tttctggact gcatctgtgg aagcaccaca gggggcctag gcctgctggg
     6841 gctctacatc aatgagaaga acgtagctct ggtcaaccag accctggaga gcttgaccga
     6901 gtactgccag ggcccgtgtc atgagaacca gacctgtatc gccactcacg aatccaatgg
     6961 gattgacatc atcatcgcct tgattctgag tgacatcaac cctctgggca agtacagaat
     7021 ggacctggtg ctacagctga agaacaacgc ctccaagctt ctgctggcca ttatggagag
     7081 cagacacgac agtgagaatg cagagagaat tctcttcaac atgagaccca aggaactggt
     7141 ggatgtcatg aagaatgcct ataaccaagg cctggaatgt aaccatgggg acgaggaggg
     7201 aggagatgat ggtgtttctc caaaagacgt tggacacaac atctacatcc tggcccatca
     7261 gttggcccgc cacaataaac tcctacagca gatgctcaag cctggatccg atccagagga
     7321 aggggatgaa gccttgaagt actatgccaa ccacaccgca cagatcgaga ttgtgcggca
     7381 cgaccggact atggagcaga ttgttttccc cgtccccaat atctgcgaat tcctcactcg
     7441 ggaatccaaa taccgggtgt tcaacacaac ggagagggat gagcaaggaa gcaaggtgaa
     7501 cgacttcttc cagcaaacgg aagatctcta caacgagatg aaatggcaaa agaagatcag
     7561 gaacaacccc gccctgttct ggttctccag gcacatctcc ctgtggggga gcatctcctt
     7621 caacctggct gtgttcatca acctggccgt ggctctcttc tacccattcg gggatgacgg
     7681 cgatgaaggt acgctctccc cgctgttctc agccctcctt tgggtagcag tggcgatctg
     7741 cacgtctatg ctgttcttct tctccaagcc tgtgggcatc cggccattcc ttgtgtctat
     7801 catgctcaga tcaatataca ccatcggtct ggggccaacg ctaatacttc ttggtgctgc
     7861 caatctatgc aataaaatcg tgttcctggt gagttttgtg ggaaaccgag gcacattcac
     7921 ccgagggtac cgagcagtca ttctggacat ggcctttctt taccacgtgg cctatgtctt
     7981 ggtttgcatg cttggcctct tcgtccacga gttcttctac agcttcctgc tttttgactt
     8041 ggtgtacaga gaagagaccc tgctgaacgt catcaaaagc gtcacacgga atggccgctc
     8101 catcatcctg actgcggtct tggctcttat cctggtctac ctgttctcca tcatcggctt
     8161 ccttttctta aaggatgact tcaccatgga ggtggacaga ttgaaaaaca gaactccagt
     8221 cacaggtaac gacggggttc ccactatgac cttaacttcc atgctgggaa cctgccctaa
     8281 ggaaaactgc tcacccacga tcccctcttc gaatgcagcc ggtgagggag gtgaggacgg
     8341 catcgagagg acctgtgaca ccctgctcat gtgcattgtc accgtgctga accagggcct
     8401 caggaatggt ggcggagttg gtgacgtgct gagacgaccc tcgaaggatg agcctttgtt
     8461 tgctgcccgg gtggtctacg acctcctttt cttcttcatc gtcatcatca tcgtccttaa
     8521 cctgattttt ggtgtaatca ttgacacttt cgctgacctc aggagtgaga agcagaagaa
     8581 agaagaaatt ctcaagacaa cctgcttcat ctgtggcttg gagagggaca agtttgataa
     8641 caagacggtg tcctttgagg agcacatcaa gtcagagcac aacatgtggc attacttgta
     8701 cttcatcgtc ctggtgaagg tgaaggaccc aacagaatac acagggcctg agagctacgt
     8761 ggctcagatg atcacagaga agaatttaga ctggtttcct cggatgcgag ccatgtcact
     8821 tgtcagcaat gaaggtgaca gtgagcaaaa tgagatccgg aacctgcagg agaagctgga
     8881 gtccactatg agtctggtga aacagttgtc ggggcagctg gcagagctga aggagcagat
     8941 gacagaacaa aggaaaaaca agcaaaggct gggcttcctt ggatcaaaca caccccatgt
     9001 gaaccatcac atgccaccgc actgacacca tgggggcacg ccgtgaccag cctttcatca
     9061 gatgcctgcc tcatcgctga gggatggaga tggaggggag cgaacagtgg ctattgttga
     9121 aaagctgaaa acaaccaagt gccaaggtgc tgagccattc agctcccaga acaatctgta
     9181 actgtgtttg cacgcttgag aaggttcaag cttggaaaaa aacaaaacaa aacagtatag
     9241 ggcacagcct ctccatgtgg caggaagcgg ccagcctgag gggctggagg gggtgggaga
     9301 gtctgatcgg ggagcggcag acctccccct gctcgatcga taggccttgg acttgtctca
     9361 cacactgact gcagtgtcca tcgtggctgg ttgaaatttt ttcttcaaac tgtggcactg
     9421 gggtcagcga gacaggaagc cacactctgc tggctaagtc taagaaattt aaaagattaa
     9481 aaaggagaat tgaaaagggt gtcgttaaac ttccgaacct tacgtgttaa ctggacattt
     9541 tcttcttggc atgagacggg ctcagagcac tacccctcag tgctttggag ttcacacccc
     9601 acccactgca aaacataact ggatcagggt ggctgtgtcc agagctctgt acagggctgt
     9661 gcaacagaaa gctttcatag aattggctaa gactgctcaa agcctggtgc ctatgtgctg
     9721 agatgttaaa gacttgggga agagaagctt gtctgtaaca ctcaggaaac aacgtttcca
     9781 gtgtatatgc tactaaagta tgtgggcatt gaaagaaaaa ctcgagggta acagccaaca
     9841 ctgagaagcg ttactcgggt ggccttgcct ttaaaagcag gttgatttat atttgaggtg
     9901 cttgacccaa gtgcttgcga tccccgaagc tgagggggtt ggggggaatc taagaattgc
     9961 attgactacg taagaatatg caacatttca acagcacatt taaggctgtt agagtaacag
    10021 cttttcaaaa tgtaggcaga tcataattcc ttcccccaaa ctgttttcat gttgactcat
    10081 gcaaccagat tttgtcaagg gaaaaaataa cttggaagga gagattcctt ttggagactg
    10141 tctgaggtgt cagagacaga cagatcatgt aagtgtgaga ccatctggtg gtgaggggcc
    10201 accagccaag acactacatt ctgaaacaga gaccctctct ggcctccaga ttctttaaac
    10261 tctcagccac caagggccac atggggtttg ttacagcaag ttttaaagct ttctggcatt
    10321 tcaatacagt tttagcagtt ggctcctaaa aataaacaaa caaacaaaca agtcaaatcc
    10381 tgggtgtgta tagacccact gtacaggcag aaactcaaat ggcttacctt ctcttgggtg
    10441 tagccttgga accaccgaga tgtactttct aactaaatgc tgcacacact aggaccaccc
    10501 agagttacaa agtgctcttg gacagggccc tgctcccctt agcctaaagt ggaaagatgc
    10561 tggtgccttg acctcaggtg ttctaggcta aaacactgca ccactgaccc tcgactcttg
    10621 taagagacct gtcttcagtt acccttaatt ctttgctaaa gcttcaaact ataatcacaa
    10681 acattttttt gaagggtatc accaaaatta ggccacggca gccattttta aagctcagga
    10741 ccatggatac ttcgacggta tttggtaaaa gtaaaatagg ctgggcgatc agaaggatag
    10801 gagctgcttc agtctgctgt aacctaaccc tccatccgtt gtgccagcag cccacagttc
    10861 gacaccgtgg cttcctcctg tgggaactat ccaaaagatt tcacctaacg agactctcac
    10921 tatgtcaaaa ttaatttttt tcagttgtac tttttctttc ccctctacaa gatgaaagat
    10981 tataaagtga aattttataa acatcaacca aagcaaaggc actttctagg acactgactt
    11041 cataaagatg ttagaaatga ggaaatttga tgtcaggtga gagtttatac ttgttatgta
    11101 tggttactaa tgcagcgggt gtagctgact gaagtttgat atagttgtat tctcacattt
    11161 atagtgatat taaaaataca gtcacctctg acttctatgc cagggaaggc ttttttaaat
    11221 tttaggttat taaaatccat attggttaaa agtcacagtt cccactgaat aatattttta
    11281 attcacagaa gggtttgttc ccaggtgtgc tccattctgc atcacaagag tttagtcgaa
    11341 gacattttct aaattaaaat aattgtttgt aattagagat cttgcactgt ctagagatat
    11401 aatattgacc aatcatatgc atgcagagat gatatttcta ccctttagaa agttgtcacg
    11461 agggcttatt ttcaggaatc tgccattttc ttttccctgt ggatagagat cacgattttg
    11521 ggagactgtt gataatttca ggaagctact tcatttgaat cagaactgac atcgtgtcaa
    11581 tccccattat ttccggctca cagcttggac ttctggctgc cttctaaaag ttgtttaatg
    11641 ataaactgta atgtgactcc atccctgaga ctacatgtgg gcatggaggc ctgggagttg
    11701 atgaagacta agacaggact tcccttccca ggatgctatc tatcgggaag ggagtgccaa
    11761 gtgcccgtcc ctgggaccca gtagatcaga gtactcctgc agagtagcga tgacctcaca
    11821 gctcagaacc cttaaacatg cagacagcca tgctgtgtag aagatgacgc atccctgaca
    11881 gctgttttaa agctttattg caagagttgt aatcttctgg cctggagacc ctgccaaaca
    11941 cactactgtg cgatgagaca cagccctgga gggagcgggc atctgaaatc cagaccagat
    12001 gccctgggag ccaggtgaag gcctaagctg catgaaactc taaggctcct gccctgagta
    12061 gggggtggga aggctgtgta agccatgcta agctctccat tttcaaactc tgacagccaa
    12121 ttccagattc cagaaagcgc tcgaggctac ccgaggccct gttctcactc tgaagtaaca
    12181 cgtgatagag ctcctgtgta taaggctcct gtgtataagg ctcctgtgta taaggctcct
    12241 gtgtataagg caatgccgag atcaaatgga actaagtgct tgtgaaagcc aagacccctg
    12301 aagaggaccc caggtataca cctcaggact gctttgacta atgaatgagg tggccgtgcc
    12361 gggactcccc tcaccaagtg gattccctgg cctctggcaa tacagaatgt ctacatggtc
    12421 tttttaaaag gtgattttta acacactgtc aggactggat aacttacaag ttaataaaat
    12481 gaatttgtat cttg
//
