LOCUS       XM_006236987            9827 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus inositol 1,4,5-trisphosphate receptor,
            type 1 (Itpr1), transcript variant X1, mRNA.
ACCESSION   XM_006236987
VERSION     XM_006236987.3
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051339.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Jan 21, 2021 this sequence version replaced XM_006236987.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9827
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..9827
                     /gene="Itpr1"
                     /gene_synonym="I145TR; InsP3R; InsP3R1; IP3R1; P400"
                     /note="inositol 1,4,5-trisphosphate receptor, type 1;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 3 mRNAs, 67 ESTs, 5 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 38 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:25262"
                     /db_xref="RGD:2933"
     CDS             279..8555
                     /gene="Itpr1"
                     /gene_synonym="I145TR; InsP3R; InsP3R1; IP3R1; P400"
                     /codon_start=1
                     /product="inositol 1,4,5-trisphosphate receptor type 1
                     isoform X1"
                     /protein_id="XP_006237049.1"
                     /db_xref="GeneID:25262"
                     /db_xref="RGD:2933"
                     /translation="MSDKMSSFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPEAG
                     DLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGANSTTDAVLLNKLHHAADLEKKQ
                     NETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSW
                     FYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQLVDNPGCNEVNSVNCNTSW
                     KIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQHVFLRTTGRQSATSAT
                     SSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDFEEECLEFQPSVD
                     PDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRH
                     LCTNTWVHSTNIPIDKEEEKPVMLKIGTSPLKEDKEAFAIVPVSPAEVRDLDFANDAS
                     KVLGSIAGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQK
                     LMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQD
                     YRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRK
                     NREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEFEGVST
                     GENALEAGEDEEEVWLFWRDSNKEIRSKSVRELAQDAKEGQKEDRDVLSYYRYQLNLF
                     ARMCLDRQYLAINEISGQLDVDLILRCMSDENLPYDLRASFCRLMLHMHVDRDPQEQV
                     TPVKYARLWSEIPSEIAIDDYDSSGASKDEIKERFAQTMEFVEEYLRDVVCQRFPFSD
                     KEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVTTIFPISKMTKGEE
                     NKGNNAEEKLKSSNVMRSIHGVGELMTQVVLRGGGFLPMTPMAAAPEGNVKQAEPEKE
                     DIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQSSETSSGNSSQEGP
                     SNVPGALDFEHIEEQAEGIFGGSEENTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGA
                     LQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQ
                     GPDEPMDGASGENEHKKTEEGTSKPLKHESTSSYNYRVVKEILIRLSKLCVQESASVR
                     KSRKQQQRLLRNMGAHAVVLELLQIPYEKAEDTKMQEIMRLAHEFLQNFCAGNQQNQA
                     LLHKHINLFLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKF
                     LQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENS
                     PLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLN
                     HCYVDTEVEMKEIYTSNHMWKLFENFLVDICRACNNTSDRKHADSVLEKYVTEIVMSI
                     VTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVA
                     KSRAIAIPVDLDSQVNNLFLKSHNIVQKTAMNWRLSARNAARRDSVLAASRDYRNIIE
                     RLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKHT
                     KQLLEENEEKLCIKVLQTLREMMTKDRGYGEKQISIDELENAELPQPPEAENSTEQEL
                     EPSPPLRQLEDHKRGEALRQILVNRYYGNIRPSGRRESLTSFGNGPLSPGGPSKPGGG
                     GGGPGSGSTSRGEMSLAEVQCHLDKEGASNLVIDLIMNASSDRVFHESILLAIALLEG
                     GNTTIQHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDDEVD
                     RDAPSRKKAKEPTTQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQSGEGTQATT
                     DKAKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLD
                     CICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDII
                     TALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEV
                     IKKAYMQGEVEFEDGENGEDGAASPRNVGHNIYILAHQLARHNKELQTMLKPGGQVDG
                     DEALEFYAKHTAQIEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKI
                     NDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFK
                     GVRGGTLEPHWSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLFL
                     LGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLYLLICAMGLFVHEFFYS
                     LLLFDLVYREETLLNVIKSVTRNGRSIILTAVLALILVYLFSIVGYLFFKDDFILEVD
                     RLPNETAGPETGESLANDFLYSDVCRVETGENCTSPAPKEELLPVEETEQDKEHTCET
                     LLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGV
                     IIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIV
                     LVKVKDSTEYTGPESYVAEMIRERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLES
                     TMKLVTNLSGQLSELKDQMTEQRKQKQRIGLLGHPPHMNVNPQQPA"
ORIGIN      
        1 aggaggtggt ggtggaggag gtggaggcag ggggtggaga gagagaaagc gcacgccgag
       61 aggaggtgtg ggtgttccgc tcccatccta acggaacgag ctccctcttc gcggacatgg
      121 gattgcccag cggctgctaa cccctgtcct ggtcctgatc cctcaaaccg gcgtggctcc
      181 ccggtcacca aggagctgac tacaaaggat ttgcatcctt ggctgggagt ccattggcta
      241 cagagtgcct gacctgggtc aggcttttca acaaggacat gtctgacaaa atgtctagtt
      301 tcctacatat cggagacatt tgttctctgt atgcagaggg atctacgaat ggatttatca
      361 gcaccttggg cttggttgat gaccgttgcg ttgtacagcc agaagctggg gaccttaaca
      421 atccacccaa gaaattcaga gactgcctct ttaagctatg tcctatgaat cgatattctg
      481 cacagaagca gttctggaaa gctgctaagc ccggggccaa cagtacaaca gatgcggtgc
      541 tgctcaacaa attgcatcat gctgcagact tggaaaagaa gcagaatgag acagaaaaca
      601 ggaaattgct ggggacggtc atccagtatg gcaacgtgat ccagctccta catttgaaaa
      661 gcaataaata cttaactgtg aataagaggc ttcctgccct gctggagaag aacgccatga
      721 gagtgacgtt ggatgaggct ggaaatgaag ggtcttggtt ttacattcag ccgttctaca
      781 agctccgctc catcggagac agtgtggtca taggtgacaa ggtagttttg aaccctgtca
      841 atgctgggca gccgctacat gccagcagcc atcagctggt ggataacccg ggctgcaatg
      901 aggtcaactc cgtcaactgt aacacaagct ggaaaatagt gcttttcatg aaatggagtg
      961 ataacaaaga tgacattcta aaaggaggtg atgtggtaag actcttccat gctgagcaag
     1021 agaagtttct cacgtgcgat gagcacagga agaagcagca cgtcttcctg aggacaaccg
     1081 gcagacagtc agccacgtcg gccaccagct ccaaagccct gtgggaagtg gaggtagtcc
     1141 agcatgaccc atgtcggggt ggagctgggt actggaatag cctcttccgg ttcaagcacc
     1201 tggctacagg gcattacttg gcagcagagg tagaccctga ctttgaggaa gaatgcctgg
     1261 agtttcagcc ctcagtggac cctgatcagg acgcatctcg gagcaggttg agaaatgccc
     1321 aagaaaaaat ggtgtactct ctggtctctg tgcctgaggg caacgacatc tcctccatct
     1381 ttgagctaga ccccacaact ctacgtggag gtgacagcct tgtcccaagg aactcctatg
     1441 tccggctcag acacctgtgt acaaacacct gggttcacag cacaaacatc cccattgaca
     1501 aggaagagga aaaacctgtc atgctgaaga ttggtacctc tcccctgaag gaggacaagg
     1561 aagcttttgc catagtcccc gtttctcctg ctgaggttcg ggacctggac tttgccaatg
     1621 atgccagcaa ggtgctgggc tccatcgctg ggaagttgga aaagggcacc atcacccaga
     1681 atgagagaag gtctgtcacc aagctgctgg aagacttggt ttactttgtc acgggtggaa
     1741 cgaactctgg ccaagacgtg cttgaagtag tcttctctaa gcccaaccga gagcggcaga
     1801 agctgatgag ggaacagaat attctcaagc agatcttcaa gcttttgcag gcccccttca
     1861 cggactgcgg ggatggccca atgcttcggc tggaggagct gggggaccag cggcacgctc
     1921 ctttcagaca catttgccga ctctgctaca gggtcctgag acactcacag caagactaca
     1981 ggaagaacca ggagtacata gccaagcagt ttggcttcat gcagaagcag attggctatg
     2041 atgtgctggc cgaagacacc atcactgccc tgctccacaa caaccgaaag ctcctggaaa
     2101 agcacatcac cgcagcagag attgacacgt ttgtcagcct ggtgcgaaag aacagggagc
     2161 ccaggttctt ggattacctc tctgacctct gtgtatccat gaataagtca atccctgtga
     2221 cccaggagct catttgtaaa gctgtgctga atcccaccaa tgctgacatc ctgattgaga
     2281 ccaagttggt tctttctcgt tttgagtttg aaggcgtttc caccggagag aatgctctgg
     2341 aagctgggga agatgaggaa gaggtgtggc tgttctggag ggacagcaac aaagagatcc
     2401 gtagcaagag tgttagggaa ttggcacaag atgctaaaga gggacagaag gaagacaggg
     2461 atgtcctcag ctactacagg tatcagctga acctctttgc aaggatgtgt ctggaccgcc
     2521 agtacctggc catcaatgaa atatccgggc agctggatgt tgacctcatc ctccgctgca
     2581 tgtccgatga gaacctcccc tatgacctca gagcatcctt ttgccgcctc atgcttcaca
     2641 tgcatgtgga ccgagatccc caggagcagg tgacccctgt gaaatacgcc cgtctgtggt
     2701 cagaaattcc ctccgagatc gccattgacg actatgacag cagtggagca tcgaaggatg
     2761 aaatcaagga gaggtttgct cagacgatgg agtttgtgga ggagtacctg agagatgtgg
     2821 tttgtcaaag attccccttt tctgataagg agaaaaataa gctcacattt gaggttgtga
     2881 acttagccag gaacctcata tactttggct tctacaactt ttctgacctt ctccgattaa
     2941 ccaagatcct cttggcaatc ttagactgtg ttcatgtgac aaccatcttc cccattagca
     3001 agatgacgaa aggcgaagag aataaaggta acaatgctga ggagaagctg aagagcagca
     3061 acgtgatgag atctatccat ggagttgggg agctcatgac ccaggtggtg cttcggggag
     3121 gaggcttttt gcccatgact cctatggctg ctgcccctga aggaaatgtg aagcaggcag
     3181 agccagagaa agaggatatc atggtcatgg acaccaagtt aaagatcatt gaaatactcc
     3241 agtttatttt gaatgtgaga ttggattata ggatctcctg cctcctgtgt atatttaagc
     3301 gggagtttga tgaaagcaat tcccagtcat cagaaacatc ctccggaaac agcagccaag
     3361 aagggccaag taatgtacca ggtgctcttg actttgaaca cattgaagag caagcagaag
     3421 gcatctttgg gggaagtgag gagaacacac ctctggactt ggatgatcat ggtggcagaa
     3481 ccttcctcag ggtcctgctc cacttgacaa tgcatgatta cccacccctg gtgtctgggg
     3541 ccctgcagct cctcttccgg catttcagcc agaggcagga ggtccttcag gccttcaaac
     3601 aggttcaact gctggttact agccaagatg tggacaacta caaacagatc aagcaagact
     3661 tggaccagct aagatccatc gtggagaagt ctgagctctg ggtatacaaa ggccagggtc
     3721 ccgatgagcc tatggacgga gcctctggtg aaaacgaaca taagaaaact gaggagggga
     3781 ccagtaagcc actgaagcac gaaagcacca gcagctacaa ctaccgagtg gtgaaagaga
     3841 ttctgattcg acttagcaag ctctgtgttc aagagagcgc gtcggtgagg aagagcagga
     3901 agcagcagca gcgactgctg aggaacatgg gtgcccatgc tgtggtgctg gagctgctgc
     3961 agatccccta tgagaaggcc gaagatacca agatgcagga gatcatgagg ctggctcacg
     4021 aatttctgca gaatttctgc gcaggcaacc agcagaacca agctttgcta cataaacaca
     4081 taaacctgtt tctcaaccca gggatcctgg aagcagtgac catgcagcac atcttcatga
     4141 acaacttcca gctgtgcagt gagatcaacg agagagtggt ccagcatttc gttcactgca
     4201 tagagaccca cggtcgaaat gtccagtata tcaagtttct ccagactatt gtcaaggccg
     4261 aagggaaatt cattaaaaag tgccaagaca tggtcatggc tgagcttgtc aattctggag
     4321 aggacgtcct cgtgttctac aatgacagag cctctttcca gactctgatc cagatgatgc
     4381 ggtccgagcg tgaccggatg gatgagaaca gccctctcat gtaccacatc catctggtgg
     4441 agctcttggc tgtgtgcaca gagggcaaga atgtgtacac agagatcaag tgcaactccc
     4501 tgctcccgct cgatgacatc gttcgtgtgg tcactcatga agactgtatc cccgaggtta
     4561 agattgctta catcaacttc ctgaatcact gctatgtgga cactgaggtg gagatgaagg
     4621 agatttacac aagtaatcac atgtggaagt tgtttgagaa tttcctcgtg gacatctgca
     4681 gggcctgtaa caacacaagt gacaggaagc atgcagactc ggttctggag aagtacgtca
     4741 ctgaaatcgt gatgagcatt gtcaccacct tcttcagctc tcccttctca gaccagagta
     4801 ccactctgca gactcgccag cctgtctttg tgcagctcct gcaaggcgtg ttccgagttt
     4861 accactgcaa ctggttgatg ccgagccaga aagcctcggt ggagagctgt atccgcgtgc
     4921 tctctgacgt agccaagagc cgggccatag ccattcctgt tgacctagac agccaagtca
     4981 acaacctctt cctgaagtcc cacaacattg tgcagaaaac agccatgaac tggcggttat
     5041 cagcccgcaa cgctgctcgt agagactctg tcctggcagc ttccagagac taccgaaata
     5101 ttattgagag gttacaggac atcgtgtctg ccctggagga ccgactcagg cccctggtcc
     5161 aggccgagct gtctgtgctc gtggatgttc tacacagacc ggaactgctt ttccctgaga
     5221 acacggatgc caggaggaaa tgcgaaagtg gaggtttcat ctgcaagctc ataaaacaca
     5281 ccaagcagct gctagaggag aatgaagaga aactgtgcat taaagtctta cagaccctca
     5341 gggaaatgat gaccaaagat agaggctatg gagaaaagca aatttccatt gatgaattgg
     5401 aaaatgccga gctgccacag ccaccggaag ctgagaactc cacagagcag gagcttgaac
     5461 caagtccacc cctgaggcaa ctggaagacc ataaaagggg tgaggcactc cggcaaattt
     5521 tggtcaaccg ttactatgga aacatcagac cttcaggaag aagagagagc cttaccagct
     5581 ttggcaatgg tccactatca ccaggaggac ccagcaagcc tgggggagga gggggaggtc
     5641 ctgggtccgg ctccacaagc cggggtgaga tgagcctggc tgaggttcaa tgtcatctcg
     5701 acaaggaagg cgcctccaat ctggtcatcg acctcataat gaatgcatcc agcgaccgag
     5761 tattccacga aagcattctc ctggccatcg cacttctgga aggaggcaac accactatcc
     5821 agcactcatt tttctgccgg ctgacggaag ataagaaatc agagaagttc ttcaaggtct
     5881 tttacgatcg aatgaaggtg gcccagcagg aaatcaaggc gacagtgacc gtgaacacca
     5941 gcgatttggg aaacaaaaag aaagatgatg aagtggaccg ggatgcccca tcccggaaga
     6001 aagccaaaga gcccacaaca cagataacag aagaggtccg ggatcagctc ttggaagcat
     6061 ctgctgccac cagaaaagcc tttaccacct tccggaggga ggccgaccct gatgaccatt
     6121 accaatctgg ggagggcacc caggctacaa cggacaaagc caaggatgac ctagagatga
     6181 gtgcagtcat caccatcatg cagcctatcc tgcgcttcct gcagctcctg tgtgaaaacc
     6241 acaaccgcga tctgcagaat ttccttcgtt gccaaaataa taagaccaac tacaacttgg
     6301 tgtgtgagac actgcagttt ctggactgta tctgtgggag cacaactgga ggccttggtc
     6361 ttctcggact gtacataaat gaaaagaatg tagctcttat caaccaaacc ctggagagtc
     6421 tgactgagta ctgtcaaggg ccttgccatg aaaaccagaa ctgcatcgcc acccacgagt
     6481 ccaatggcat cgatatcatc acagccctca tccttaacga tatcaaccct ctggggaaga
     6541 aacggatgga cctggtgtta gaactgaaga acaatgcttc aaagctactc ctggccatca
     6601 tggaaagcag acacgatagt gaaaatgcag agaggatcct gtacaacatg aggcccaagg
     6661 agctggtgga agtgatcaag aaggcctaca tgcaaggcga agtggagttt gaggatgggg
     6721 agaacggtga ggatggagca gcctccccca ggaacgtggg ccataacatc tacatcctcg
     6781 ctcaccagtt ggctcggcat aacaaagaac ttcaaaccat gctgaaacct ggaggccagg
     6841 tggatggcga tgaagctctg gagttctatg cgaagcacac agcacaaatt gagattgtca
     6901 gactggaccg aactatggaa cagattgtct tccctgtgcc cagcatctgt gaatttctga
     6961 ctaaggaatc gaaacttcga atatattaca ccacagagag ggatgagcaa ggcagcaaga
     7021 tcaatgactt cttcctgcgc tccgaggacc tctttaatga gatgaactgg cagaagaaac
     7081 ttcgagccca gcctgtcttg tactggtgcg cccgaaacat gtctttctgg agcagcatct
     7141 ccttcaacct ggccgtcctg atgaacctgc tggtggcgtt tttctaccca tttaaaggag
     7201 tgagaggagg aacactagag ccgcactggt ccggcctcct gtggacagcc atgctcatct
     7261 ctctggcaat tgtcattgcg ctgcccaagc cccatggcat ccgggcctta attgcttcta
     7321 caatcctacg actgatattt tcagttggat tacagcccac actgtttctg ctgggagctt
     7381 tcaatgtctg caataaaatc atcttcctga tgagctttgt gggcaactgt gggaccttca
     7441 ccagaggcta ccgagccatg gttctggacg ttgagttcct ctatcatttg ctgtatctac
     7501 tgatctgtgc catgggcctc ttcgtacatg agtttttcta tagtttgctg ctttttgatt
     7561 tagtgtacag agaggagact ttgcttaatg tcattaaaag tgtcacccgc aatggacggt
     7621 ccatcatctt gacagcggtc ctggctctga ttctggttta cctgttctca attgtgggct
     7681 acctgttctt caaggatgac tttatcttgg aagtagacag gttgcccaat gagacagctg
     7741 gtccagaaac tggtgagagt ttggccaacg atttcctgta ctctgatgtg tgccgggtag
     7801 agacggggga gaactgcacc tctccggcac ccaaagaaga gctgctccct gtggaagaaa
     7861 cggaacagga taaggagcac acgtgtgaga cactgctcat gtgcatcgtc accgttctga
     7921 gtcacgggct gcggagtggg ggcggagtag gagatgtgct caggaagcca tccaaagagg
     7981 agcctctgtt tgctgcaagg gtgatctatg acctcctctt cttcttcatg gtcatcatca
     8041 ttgtcctgaa cctcattttt ggggtcatca tcgacacctt tgctgacctg aggagtgaga
     8101 agcagaagaa ggaagagatc ttaaaaacca cgtgcttcat ttgtggcttg gaaagggaca
     8161 agtttgacaa taagaccgtc acctttgaag agcacattaa ggaagaacac aacatgtggc
     8221 actatctgtg cttcatcgtg ctggtgaaag tgaaggactc caccgagtac accgggcccg
     8281 agagctacgt ggcagagatg atcagggaaa gaaaccttga ttggttcccc aggatgagag
     8341 ccatgtccct ggtcagcagt gactctgaag gggaacagaa cgagctgagg aacctgcagg
     8401 agaagctgga gtccaccatg aagctggtca ccaatctttc tggccagctg tcagaactaa
     8461 aggaccagat gacagaacaa aggaagcaga aacaaagaat tggccttcta ggacatcctc
     8521 ctcacatgaa tgtcaaccca cagcagccag cctaagcaaa tgagacggag ggactgtact
     8581 caaccctttt taaattattg tcagcgtggg tctggctctt ggttctgatc tgccctctaa
     8641 ggttacatgt gcgcttagta catttgtaaa tactcggttt tgtattgtat gtatatgatt
     8701 gcaattctca gaggtttgga ctttcgtatt gtaattagct ctgttggcat ggtgacttgt
     8761 cactcctgcc aaaaatatta aaaatgcctt ttttggaagg actacagaaa gtacctgatt
     8821 tgcacttgaa ccagattata gatttaaaag tatatgacat gtattttgta tttaaaacta
     8881 gaatagccag tatttatgtt ttttataaaa ctgtgcaata caaattatgc aatcaccata
     8941 actctgtaac tcctgagtgt cttaagggag tgcgcatctt tgaagctgat ctgttaatac
     9001 ttatgtaata aatggttaaa tatcaaatga tgatgctgct gccaaaatta tattaatagc
     9061 aagtttctgg cccctgggca attttgtacc ttgtaattat cctatggtga tgctgtttct
     9121 cgttgctaat ggcattagtg cctcgtatcc tagtgataac tccaggtctg tgaaccattc
     9181 aaacaacatt catttttgag acaaagcaac tttagtttca agggtaattt taagcttcaa
     9241 aattaatcat ttaaagtatt tctttaagag agccatgtta gaggctcaca cgttagcttg
     9301 aaaggagtcg atgaaataat ttttttaaag ggaacttttt acacgacgtt tggaataaca
     9361 gcatattgct gaccagtcag tgtcatctcc caggtgaatt ttgatgtcac gttatagtca
     9421 aatgagctag ctgatggttt ctagattctc ttcatctgaa ccaacatgat gcagtaggtg
     9481 agaagttatt atgcatatat acacatatac atccatataa ggcaaagtag gagctgtccc
     9541 cttaggatgc atagctgccc ccttagggtg cagagctcaa cactgacagt gctgttctga
     9601 gagagccacg tttgggtttt atttctttgt cacatgattt cttttctgga tgtgtgcaag
     9661 tataacagga agtgttttct acctgttgct tgttttgtac ctgggtctcg ttttactaga
     9721 ccatctctgc acaaaagttt aaaaaatgaa ccgtaagcag agttctgaag caagtcaagt
     9781 ttgtaagtgc atacctgaaa ttatttaata aatgacgcag aatacta
//
