LOCUS       NM_001034946            1143 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus intelectin 1 (Itln1), mRNA.
ACCESSION   NM_001034946 XM_573509
VERSION     NM_001034946.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1143)
  AUTHORS   He,P., Guo,Y., Wang,S. and Bu,S.
  TITLE     Innovative insights: ITLN1 modulates renal injury in response to
            radiation
  JOURNAL   Int Immunopharmacol 133, 111987 (2024)
   PUBMED   38652961
  REMARK    GeneRIF: Innovative insights: ITLN1 modulates renal injury in
            response to radiation.
REFERENCE   2  (bases 1 to 1143)
  AUTHORS   Valencia-Martinez,A., Schaefer-Graf,U., Amusquivar,E., Herrera,E.
            and Ortega-Senovilla,H.
  TITLE     Relationship of ANGPTL6 With Neonatal Glucose Homeostasis and Fat
            Mass Is Disrupted in Gestational Diabetic Pregnancies
  JOURNAL   J Clin Endocrinol Metab 107 (10), e4078-e4085 (2022)
   PUBMED   35876300
REFERENCE   3  (bases 1 to 1143)
  AUTHORS   Jin,Z., Xia,F., Dong,J., Lin,T., Cai,Y., Chen,J., Chen,X.,
            Huang,Z., Wang,Q., Chen,H. and Zhang,J.
  TITLE     Omentin-1 attenuates glucocorticoid-induced cardiac injury by
            phosphorylating GSK3beta
  JOURNAL   J Mol Endocrinol 66 (4), 273-283 (2021)
   PUBMED   33739937
  REMARK    GeneRIF: Omentin-1 attenuates glucocorticoid-induced cardiac injury
            by phosphorylating GSK3beta.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1143)
  AUTHORS   Lage,R., Cebro-Marquez,M., Rodriguez-Manero,M.,
            Gonzalez-Juanatey,J.R. and Moscoso,I.
  TITLE     Omentin protects H9c2 cells against docetaxel cardiotoxicity
  JOURNAL   PLoS One 14 (2), e0212782 (2019)
   PUBMED   30794687
  REMARK    GeneRIF: These data suggest that omentin treatment may contribute
            to decrease susceptibility to docetaxel-induced cardiotoxicity.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1143)
  AUTHORS   Gu,N., Dong,Y., Tian,Y., Di,Z., Liu,Z., Chang,M., Jia,X., Qian,Y.
            and Zhang,W.
  TITLE     Anti-apoptotic and angiogenic effects of intelectin-1 in rat
            cerebral ischemia
  JOURNAL   Brain Res Bull 130, 27-35 (2017)
   PUBMED   28017783
  REMARK    GeneRIF: Data suggest that the successful delivery of
            LV-intelectin-1 ameliorated ischemic brain injury. It promoted
            endothelial cell function and revasc ularization, and inhibited
            apoptosis in response to ischemia by stimulating the Akt-eNOS
            signaling pathway.
REFERENCE   6  (bases 1 to 1143)
  AUTHORS   Bubenek,S., Nastase,A., Niculescu,A.M., Baila,S., Herlea,V.,
            Lazar,V., Paslaru,L., Botezatu,A., Tomescu,D., Popescu,I. and
            Dima,S.
  TITLE     Assessment of gene expression profiles in peripheral occlusive
            arterial disease
  JOURNAL   Can J Cardiol 28 (6), 712-720 (2012)
   PUBMED   22721676
REFERENCE   7  (bases 1 to 1143)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   8  (bases 1 to 1143)
  AUTHORS   Voehringer,D., Stanley,S.A., Cox,J.S., Completo,G.C., Lowary,T.L.
            and Locksley,R.M.
  TITLE     Nippostrongylus brasiliensis: identification of intelectin-1 and -2
            as Stat6-dependent genes expressed in lung and intestine during
            infection
  JOURNAL   Exp Parasitol 116 (4), 458-466 (2007)
   PUBMED   17420014
REFERENCE   9  (bases 1 to 1143)
  AUTHORS   Wrackmeyer,U., Hansen,G.H., Seya,T. and Danielsen,E.M.
  TITLE     Intelectin: a novel lipid raft-associated protein in the enterocyte
            brush border
  JOURNAL   Biochemistry 45 (30), 9188-9197 (2006)
   PUBMED   16866365
REFERENCE   10 (bases 1 to 1143)
  AUTHORS   Yang,R.Z., Lee,M.J., Hu,H., Pray,J., Wu,H.B., Hansen,B.C.,
            Shuldiner,A.R., Fried,S.K., McLenithan,J.C. and Gong,D.W.
  TITLE     Identification of omentin as a novel depot-specific adipokine in
            human adipose tissue: possible role in modulating insulin action
  JOURNAL   Am J Physiol Endocrinol Metab 290 (6), E1253-E1261 (2006)
   PUBMED   16531507
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC099766.1.
            
            On Oct 21, 2005 this sequence version replaced XM_573509.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC099766.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389, SAMN16676784
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1143
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q24"
     gene            1..1143
                     /gene="Itln1"
                     /note="intelectin 1"
                     /db_xref="GeneID:498284"
                     /db_xref="RGD:1561048"
     exon            1..62
                     /gene="Itln1"
                     /inference="alignment:Splign:2.1.0"
     exon            63..126
                     /gene="Itln1"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..1010
                     /gene="Itln1"
                     /note="intelectin 1 (galactofuranose binding)-like"
                     /codon_start=1
                     /product="intelectin-1 precursor"
                     /protein_id="NP_001030118.1"
                     /db_xref="GeneID:498284"
                     /db_xref="RGD:1561048"
                     /translation="MTQLGFLLFLIVATRGGSAAKEDLETNKGTHSFFDSLSRSCKEI
                     KEENTGAQDGLYFLRTENGVIYQTFCDMTTAGGGWTLVASVHENNMGGKCTVGDRWSS
                     QQGNRADYPEGDGNWANYNTFGSAEGATSDDYKNPGYFDIQAENLGIWHVPNNSPLHS
                     WRNSSLLRYRTFTGFLQHLGHNLFGLYQKYPVKYGEGKCWTDNGPALPVVYDFGDAQK
                     TASYYSPYGQKEFTAGFVQFRVYNNERAASALCAGMKVTGCNSEAHCIGGGGFFPEGN
                     PLQCGDFGAFDWNGYGTHIGYSSSREITEAAVLLFYR"
     exon            127..225
                     /gene="Itln1"
                     /inference="alignment:Splign:2.1.0"
     exon            226..473
                     /gene="Itln1"
                     /inference="alignment:Splign:2.1.0"
     exon            474..632
                     /gene="Itln1"
                     /inference="alignment:Splign:2.1.0"
     exon            633..753
                     /gene="Itln1"
                     /inference="alignment:Splign:2.1.0"
     exon            754..857
                     /gene="Itln1"
                     /inference="alignment:Splign:2.1.0"
     exon            858..1131
                     /gene="Itln1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aagaaaggtt cctgtcatta gccggccagc aactctcagc tcctgccagg tgcagaggga
       61 agacgaccat gacccaactc ggctttctgc tgtttctcat cgttgccacc agagggggca
      121 gtgcggctaa agaggacctg gaaaccaaca aagggaccca ttctttcttt gactctctgt
      181 ccagaagctg caaggaaatc aaggaggaga acacaggggc tcaagatggc ctctatttcc
      241 tgcgcacgga gaatggtgtc atctaccaga ccttctgtga catgaccact gcaggtggtg
      301 gctggaccct ggtggctagc gtgcatgaga acaacatggg tgggaagtgc acagtgggcg
      361 atcgctggtc cagtcagcaa ggcaacagag cagattaccc agagggggat ggcaattggg
      421 ccaactacaa cacctttggg tctgcagagg gtgccacaag tgatgactac aagaaccctg
      481 gctacttcga catccaggct gagaacctgg gcatctggca cgtgcccaac aacagccccc
      541 tgcacagctg gaggaacagc tccctgctgc ggtaccgcac cttcactggc ttcctgcagc
      601 atctgggcca taatctgttt ggcctctacc agaagtaccc ggtgaaatat ggagaaggaa
      661 agtgttggac tgacaatggc ccggcgttac ctgtggtcta tgactttggt gatgctcaga
      721 agactgcctc ttattattcc ccctatggcc agaaggaatt cactgcagga tttgttcagt
      781 tcagagtgta taacaatgag agagcggcca gtgccttgtg tgctggcatg aaggtcactg
      841 gatgtaattc tgaagctcac tgcatcggtg gaggaggatt ctttccagaa ggtaacccct
      901 tgcagtgtgg agacttcggg gcgtttgatt ggaacggata cggaactcac attgggtaca
      961 gcagtagccg ggagataact gaagcagccg tgcttctgtt ctatcgctga gagctctgtg
     1021 gggtggaccc agacttctcc aatctgtagg ctcccaggca tggcgacaca atgacctagt
     1081 aactagaatg ctaatgacca gaaaagcgga ataaatcatg ttcattgaaa aaaaaaaaaa
     1141 aaa
//
