LOCUS       XM_039096454            7826 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus inter-alpha-trypsin inhibitor heavy
            chain 5 (Itih5), mRNA.
ACCESSION   XM_039096454
VERSION     XM_039096454.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051352.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039096454.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7826
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..7826
                     /gene="Itih5"
                     /note="inter-alpha-trypsin inhibitor heavy chain 5;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 36 ESTs, 8 long SRA reads, 5 Proteins, and
                     99% coverage of the annotated genomic feature by RNAseq
                     alignments, including 69 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:684327"
                     /db_xref="RGD:1591485"
     CDS             181..3042
                     /gene="Itih5"
                     /codon_start=1
                     /product="inter-alpha-trypsin inhibitor heavy chain H5"
                     /protein_id="XP_038952382.1"
                     /db_xref="GeneID:684327"
                     /db_xref="RGD:1591485"
                     /translation="MLLLLGLCLGLPLFSESQEEAQIWDDTSEQVMLRVPRQLRLLQR
                     LKTKPLMAEFSVKSTIISRYAFTTVSCRMLNRASEDQDAEFQMQIPESAFITNFTMLI
                     GDNVYQSEITEKEKKSSDRIKEKRNRTTDDNEEKGTDMFKASLVIPSKDKAAFFLSYE
                     ELLQRRLGKYEHIISVRPQQLVGRLTVEVNILERSGITSLEVLPLHNSRKKGSGKAEG
                     DEGPPPSTIINHNETFAKVVFKPTVVQQAKIAQNGILGDFIIQYDVKREQNIGDIQVL
                     DGYFVHYFAPKNLPPLPKNVVFVLDISASMVGAKLQQTREALVTILNDLRPQDRFNII
                     GFSNRIKMWKDHLLPVTPDNIRNGKIYMYHLSPTGGTDINGALQTAIKLLNNYVAQND
                     IEDRSVSLIIFLTDGKPTFGETNTLRILSNTKEATGGQICIFTVGIGNDVDFRLLEKL
                     SLENCGLTRRVHEEEKAGAQLIGFYDEIRTPLLSDIRIDYPPDAVERVTKTLFPNYFN
                     GSEIVIAGKMADKKFDQLHVEVTASNSKKFVILKRDIPVESRKMGNDVSVTPGSVSGG
                     GKDPNHLERLWSYLTVKELLSSWVQSNSEQEKEQLRQKAQALALNYHFLTPFTSMKLK
                     KPGLHPNQLEDTHGMSAATGPTTVVQNLREASMQPEPAPKKPYGPRIKISKTSVDGDP
                     HFVVDFPISKLTVCFNIDGEPGDILRLVSDHLGSGVTVNGELIGAPAPPNGHKKHRTY
                     FRTITILINQPERSYLEITPNRVILDGGDRLVLPCNQSMVVGSRGLEVSVSANANVTV
                     TIQGTIAFVILIHLYKKPAPFQRNHLGFYIANSKGLSHNCHGLLGQFLNQDAKLVGAP
                     EEYGKNLSNHQPSPRAEGMPEAILKVKGRRVPVVWKQRKIYNGLEQVDCWFDKNNAAK
                     LIDGVYKDYLALHPFDTESARGPSMSRKAEPDSLHEESA"
ORIGIN      
        1 ctggtggtgc agagaccgga ctccggctgg cctggagggc ataaagaggg cggggatctt
       61 gatgggcgtg gctttggtgg aggcggggct gaatggagcg cttctctttg cagccgcagc
      121 tattccaact ctctgaaaat ccttcccggt cccagagagg tcgcgcgctc cggcttcgcc
      181 atgctcctgc tgctagggct gtgcctgggg ttgcccctct tctccgagtc ccaggaagag
      241 gcacagatct gggatgacac ctcggagcaa gtcatgctca gggtccccag acaactcagg
      301 ctgttgcaga ggctgaaaac caagcccttg atggcggagt tttcggtgaa gtctaccatc
      361 atttcccgct atgcctttac cacggtgtcc tgcagaatgc tcaacagagc ttctgaagac
      421 caggacgctg agttccagat gcagattcca gaatcagctt tcatcaccaa cttcaccatg
      481 cttataggag acaacgtgta tcagagtgaa attacagaga aagaaaagaa aagcagtgat
      541 cgcataaaag aaaaaaggaa cagaaccacg gacgataatg aggagaaggg gacggacatg
      601 ttcaaagctt ctttagtgat tcccagcaag gacaaagctg ccttcttcct cagttatgaa
      661 gaacttctgc agaggaggct ggggaaatac gagcatatca ttagcgtgcg cccacagcag
      721 ctggtgggga ggctgactgt ggaggtgaac attctggagc ggtcgggtat cacgtccttg
      781 gaagtgctgc cccttcacaa cagcaggaag aaaggcagcg ggaaggcgga aggtgacgag
      841 ggtcctcctc cttctactat catcaaccac aacgaaacat tcgccaaagt tgtttttaag
      901 cctaccgtgg tgcaacaagc taaaattgcc cagaatggga ttttgggaga tttcatcatt
      961 cagtatgatg tcaagagaga gcagaatatc ggcgatatcc aggttctaga tggttacttc
     1021 gtgcactact ttgctcctaa aaacctccct cctttaccta agaacgtggt cttcgtgctc
     1081 gacatcagtg cctccatggt gggagcgaaa ctccagcaga cccgggaggc cctggtcaca
     1141 attctcaacg acctccgacc ccaggatcgc ttcaatatca ttgggttctc caaccggatt
     1201 aaaatgtgga aggaccactt gctacccgtg actcctgaca acattaggaa tggcaaaatc
     1261 tacatgtatc atctgtcgcc cactggaggc acggacatca atggggccct tcaaactgcc
     1321 atcaaactgc tcaacaacta cgtggcccag aatgacatcg aagatcgaag cgtgtccctc
     1381 atcatcttcc tcacggatgg gaaacccacc ttcggagaga ccaataccct caggattctc
     1441 agcaatacca aggaagccac tggaggccag atctgcatct tcaccgttgg catcggcaat
     1501 gacgtggact tcagactgtt agagaagctt tcgctggaga actgcggtct cacgaggcgc
     1561 gttcacgagg aggaaaaggc gggagcacag ctcatcgggt tctacgatga gatccggacg
     1621 ccgcttcttt ctgacatccg catagattac cctcctgacg cggtagagcg cgtcaccaaa
     1681 accctgttcc ccaactactt caacggctcc gagattgtga ttgcaggcaa gatggcggac
     1741 aagaagtttg atcaactgca cgtggaggtc actgccagca acagtaagaa atttgtcatc
     1801 ctgaagagag acatccctgt ggagtcccgg aagatgggga atgacgtctc cgtcacgccc
     1861 ggctcagtca gcgggggcgg gaaggacccc aaccatctcg agcgtctttg gagctacctc
     1921 acggtgaagg agctgctgag ttcctgggtg cagagcaaca gtgaacaaga gaaagagcag
     1981 ctgaggcaaa aggcccaggc tttagccttg aactaccact tcctcacccc cttcacctcc
     2041 atgaagctga agaagccggg gctccacccg aaccagctgg aggacaccca cggcatgtct
     2101 gcagccacag gacccacgac agtggtgcag aacctgcgag aggccagcat gcagccagag
     2161 cctgctccca agaaaccata cggcccaaga attaaaatct ctaagacatc ggtggatgga
     2221 gatcctcatt ttgttgtgga tttccccata agcaaactca ctgtctgctt taacattgac
     2281 ggagagcctg gggacatcct acggctggtc tctgatcacc tgggctctgg tgtgaccgtg
     2341 aacggagagc ttattggggc ccccgcacct ccaaatgggc acaagaaaca tcgcacatac
     2401 ttccgcacca tcaccatcct catcaaccag ccagagagat cttaccttga gatcacaccg
     2461 aacagggtca tcctggatgg tggggacagg ctggtcctcc cctgcaacca gagcatggtg
     2521 gtagggagtc gaggactgga ggtgtctgtg tctgccaacg ccaacgtcac cgtcaccatc
     2581 cagggcacaa ttgcttttgt catccttatc cacctctaca aaaagccagc acccttccag
     2641 agaaaccacc tgggcttcta catcgccaac agcaaaggcc tttctcacaa ctgccacggg
     2701 ctgttaggtc agttcctgaa ccaggatgcc aaactcgtgg gagctcctga ggaatacggc
     2761 aagaatctta gtaatcatca gccatctcct cgggcagaag ggatgcccga ggctatcttg
     2821 aaggtgaagg ggcgcagagt tccagtggtc tggaaacaaa ggaagattta caacgggctg
     2881 gagcaggttg actgctggtt tgacaaaaac aatgccgcca agctgattga cggtgtctat
     2941 aaggactacc tggcattgca tccatttgac acagagagtg cccggggccc gagcatgtcc
     3001 aggaaagctg agcctgacag cctgcatgag gagagtgcct aaaagggaag tgacattggg
     3061 tctactctgg atgcaattat ttttgttcca tgcgaccacc tcggctcttg ctatgagcgg
     3121 tactgcggta gcctgcccca tggtggaggg gaggtccaat gtctcctaga gcaatgagtc
     3181 aaggcaggaa gctggaatga aaatatcaca ttctacttcc cttcctgcct tccttgtccc
     3241 atctatacta gataagaatg gtaggagtaa ttaagtaaaa tcggagcacc tggcttaccc
     3301 atcatattct accgtgacgt aatgctttct gaggaagcgg ggttgccttg tcatttgttt
     3361 tctctgtaaa tggtgtccac tctgccttgt accctctatt aatgctttgg aagatctctt
     3421 tccagttgcc ttctccagat ggtgctccca ggctctcctt ctgaggtaat ttacatagag
     3481 tccaggcaca caaatagttt gtacattgga tctctaaaca actaggtctt ttcttagcag
     3541 aagactcccc ccgcccccac tgtggcatcc tgcccagtcg atgtcccaga tactgatctc
     3601 gtcctgattg gctctgcagg tcacttggcc ttgctggcgg gtggtttcca attgattcca
     3661 ataaaccaag tagtttcaat aaataggaaa actgcccatg gacgtctttt gctggcttgc
     3721 cttggtgccg gagagccagc gaattgaaaa ataaaccttg tactcagagt ttgctcttgc
     3781 cttcggatgt ccgggaaata ataaatcaga cgagaacaga gcgtgacaca cacacagatg
     3841 cagcctagaa tgagcggctc agcatacctg tgggaggaat caacgtctac attctcagag
     3901 ggaagtggac acaggcctgc acccgtgact gccgcacata agctagcagc agcagcagca
     3961 gcagcagcag cagcagcagc atcagcagca gcagcagcag cagcagcagc agcagcagta
     4021 gcagcgggta tctacagaag ataggaccca tcaatactcc atccaggatg ggggaaggca
     4081 tcatgaggcc ctactcctgc ctaaaaggct atgggcagtt aacagttgct ggagaagggg
     4141 gtggtcatat atagccctta gtcccaaagc cactgctagg ttgcccttgc tcaaggaaat
     4201 aatccccaat ttttagcaag caaccctagt tgaatacggt gaatcacata ttcataaaga
     4261 gacacagaga taaggcatgg tgtgttgggg ggtgggggac ttctgaggac aaagataacc
     4321 ataagggaag actgtgggaa ttggggatgt gtgatccaat gcatacgaca tatgcatggg
     4381 tttgtgagcg aataagccag aggacagaaa atcaaagaag agattcccac atctcagagg
     4441 agatgagtaa ggatgagtaa ggcatgagtt ctagttccag aacttagagg cgaatctgct
     4501 caggagaggg ttgcaatcag ggagggggct tctaaaggtt aaacgtaacc ttactgtaac
     4561 tctcctccat ccagcctatc cagcccattc aagagcaacg gggaatcagg agaacatgga
     4621 gctccattct tacacttggc tcttcctggc tgtgtttggc tttgtcaggg ctggtgagct
     4681 gcctgggacg ggtgaacagg gactgatgga attgaacagc agagaaagag aaaaatgtgc
     4741 tagggggaag caggagagtt ttgacgtaga ccaccagagt gaaggcgtcc ccacgtaagg
     4801 tttcttccct cagcaccttg aggtaccctc ctccacagtg aaacaggaag gctgcttagc
     4861 acttggagag agatcagcat caagaaaact gttttccctc ctgcgggaag catttgagca
     4921 gcacaatgac atccacatgt tcctgtctga cccgggcagc ctaaagagcc agttagggcc
     4981 aagtgagtcc ctttctctct gttccgtgaa cctaccaggc cacagctggc cagctgtgct
     5041 ctttatctga cttcccgtgc tcccagattc atctactcgt tttcaggcca ggagtgcaaa
     5101 gatgagtaac ccgtatggct gccagatgtt accatctttt caggcttagg gaaaggggga
     5161 tctcagacag gcctagccag tgctggtccc aggctgttgc tattacataa ttcccaactg
     5221 gagagacact cggagcaaca atacgtgtgc gttgttcttg ataaccttct tcaccatcaa
     5281 cgggggatat cattaggcaa gaacagcttc cacatgctgt tgtctggggt cagaagcaca
     5341 tgggtgatcc cggcaagatg cccaacactc gctgtcctgt ctagcaacca agtcagctta
     5401 aaagtttcag agaggtttta cttagaaatc ccttttatct ttagacagac attctacaaa
     5461 tgtagctctc tctctctctc tctctctctc tctctctctc tctctctccc tccctccctc
     5521 cctccctccc tccctccctc cttccctcct tctgctattt actatttagc aatctaaatt
     5581 atctgctata gctaaccata caccaacaga aaacatttca tttaactggg cacgtgcatt
     5641 gtagatcgaa cactcaaaga actgtcatgg agaggactgt actttcaaat ggggaaacag
     5701 aggcagctga gccactctcc ccaagtcaca tataagacgt agagtagggc tacagctgaa
     5761 cccgaaggat tcacatgtga ggtctgacac tcttttgccg cctggtcaag catttctttt
     5821 cctcgagcgt tttgtaaaaa gatggggtgg gagtttacca gataaacaat tggccgggct
     5881 ggagaaaaat gcagaagtta aatgggataa atcgagatgt tattacagca gttaattatg
     5941 atgagttggt gaacggaatt gttgagcaat attgtggctc tggcttcatt ttaaagagac
     6001 ttctcattca agtttcaaag aaaatgacct acctcctagc cattcataca tgtgttgtat
     6061 cttcttccat tcaacctttc catgatctac cccttcatgg atgtgtgttg aggtgaggca
     6121 gagggatatc cctttgggcc ccagaagtca ccctgaggat gcagagacag cagctcatgg
     6181 tttttatcag gagagacagt caatatttac ctgacgttca ggaggcagag gcaggcagat
     6241 ctttgatact gaggccagtc tggtctacat aatgagttcc aggacagcca gggctatgta
     6301 gagggtgcta tgttgagacc gtcagaaaaa ccagtgtgtg tgtgtgtgtg tgtgtgtgtg
     6361 tgtgtgtgtg tgtgtgtgtg tgtgtgtgtt ttaaaacctg aactgtatgt tctcacggat
     6421 agattaagaa gagggttctt tgggtaaata aatgccgtag actaaaagca tcctttcaaa
     6481 acacacatgc ttaagtctaa atctcctctg taatggtccc tccaaatgga atatttcaga
     6541 aagggtcacg tcctgagaac ggaggtcttg gggactggtt tatagtgttc gtgagcagaa
     6601 acttacacag ggatatccga tgggagagag agggtagaaa tactgcaaat agcgaactcg
     6661 tgtatgaaaa cttcaaaaag tgtttagttc ataataaaca ggggatctgg ttggtaaagc
     6721 attcccttgc aagcacaagg aactgagctc agtcaccaga actcaaaaaa gtcaggcatt
     6781 ggggacgcac gtctctaatc ccactactgg ggaggctgag gcaggcagga ccctggggct
     6841 tgttggccag tcagtttact gtatttagtg aatctcaggg cagtgagaga gtctgctcag
     6901 agaaagggga tgtcatctga agaatggaaa ccaaggtgat cctctgccct ccgtgaagtg
     6961 tgcatgaaca cttggacata tatgtgtagc tacatgtatg aaaacacaca cacacacaca
     7021 cacacacaca cacacacaca cacacacaca cacacttcag gtctgtgcct tgatccggat
     7081 cttctcagtc tccagacctg ttagcagtaa acgcattttg tttaaactgc ccggcttaaa
     7141 gtattctttg tatagcaacc caggctcact gaggaaaaga aagactccac agcataagtt
     7201 ttcgccttca ggcgacccag aatatacaga agcaatgctg ttgttagaat ctgcaagagt
     7261 cctgcaagcc gaaggacatg gtccagctaa aataaacagc aagtacaata acacagctaa
     7321 ccaaatactt agagatgcaa cattaaatat ttattttagc ccttttcaaa taaatgggta
     7381 cagattgttc gcatcccaag agacgtttgt ttcttaaacg tttgtaaaaa aaaaaaaaat
     7441 aatgtctaaa aacaaacagc acagtctgtt tattttttag aggaaactga aatcagggct
     7501 actggaataa aacttgacca ttctaaccgc aacgcttgct tgtagagaat tctgcatttc
     7561 agtcctgaat gtaagtattc ttgtctcagt gatgtccgac actgacggat atgacagtgg
     7621 tcctgtatgg ttataagaga actgacgatc cagttgccca gtactgttac tctattttta
     7681 atgtctagat ctgttcacgt gcacaaatat tcaccattgt gttatagctg cttaaaggat
     7741 ccatagtcac actacatatg tttatattcc agaagcaata ggacatgccg tgtagaatcg
     7801 gtgtataata aacgataccg tctaga
//
