LOCUS       NM_001017505            2314 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Rattus norvegicus integrin subunit beta like 1 (Itgbl1), mRNA.
ACCESSION   NM_001017505 XM_573839
VERSION     NM_001017505.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2314)
  AUTHORS   Chen,X., Li,X., Wu,X., Ding,Y., Li,Y., Zhou,G., Wei,Y., Chen,S.,
            Lu,X., Xu,J., Liu,S., Li,J. and Cai,L.
  TITLE     Integrin beta-like 1 mediates fibroblast-cardiomyocyte crosstalk to
            promote cardiac fibrosis and hypertrophy
  JOURNAL   Cardiovasc Res 119 (10), 1928-1941 (2023)
   PUBMED   37395147
  REMARK    GeneRIF: Integrin beta-like 1 mediates fibroblast-cardiomyocyte
            crosstalk to promote cardiac fibrosis and hypertrophy.
REFERENCE   2  (bases 1 to 2314)
  AUTHORS   Abonnenc,M., Nabeebaccus,A.A., Mayr,U., Barallobre-Barreiro,J.,
            Dong,X., Cuello,F., Sur,S., Drozdov,I., Langley,S.R., Lu,R.,
            Stathopoulou,K., Didangelos,A., Yin,X., Zimmermann,W.H., Shah,A.M.,
            Zampetaki,A. and Mayr,M.
  TITLE     Extracellular matrix secretion by cardiac fibroblasts: role of
            microRNA-29b and microRNA-30c
  JOURNAL   Circ Res 113 (10), 1138-1147 (2013)
   PUBMED   24006456
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC087076.1.
            
            On Apr 29, 2005 this sequence version replaced XM_573839.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC087076.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2314
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15q25"
     gene            1..2314
                     /gene="Itgbl1"
                     /note="integrin subunit beta like 1"
                     /db_xref="GeneID:498564"
                     /db_xref="RGD:1560635"
     exon            1..190
                     /gene="Itgbl1"
                     /inference="alignment:Splign:2.1.0"
     CDS             93..1577
                     /gene="Itgbl1"
                     /note="integrin beta-like protein 1; integrin, beta-like
                     1"
                     /codon_start=1
                     /product="integrin beta-like protein 1 precursor"
                     /protein_id="NP_001017505.1"
                     /db_xref="GeneID:498564"
                     /db_xref="RGD:1560635"
                     /translation="MHPPGFKNFLLLVSSLFFIGLSAAPQSFSPSLRSLSGAPCRLSR
                     AESERRCRAPGQPPGSALCHDRGRCECGVCICHVTEPGTYFGPLCECHDWVCETYDGK
                     TCAGHGTCDCGKCKCDVGWSGEACQYPTKCDLTKKISNQMCKNSQDVICSNAGTCHCG
                     RCKCDNSDGHGLIYGKFCECDDRECIDDETEEICGGHGKCYCGNCYCEAGWHGDKCEF
                     QCDITPWESKRRCTSPDGKVCSNRGTCVCGECSCHDVDPTGDWGDIHGDTCECDERDC
                     RAVYDRYSDDFCSGHGQCNCGRCDCRAGWYGKKCEHPKNCPLSAEESTRKCQGSSDLP
                     CSGRGRCECGRCTCYPPGDSRVYGKTCECDDRRCEDLDGVVCGGRGTCSCGRCVCEKG
                     WFGKLCQHPRKCNMTEEQSRSLCESADGTLCSGKGSCHCGKCICSGEEWYISGEFCDC
                     DDRDCDKHDGLICTGNGICSCGNCECWDGWNGNACEIWLGTEYP"
     exon            191..408
                     /gene="Itgbl1"
                     /inference="alignment:Splign:2.1.0"
     exon            409..555
                     /gene="Itgbl1"
                     /inference="alignment:Splign:2.1.0"
     exon            556..678
                     /gene="Itgbl1"
                     /inference="alignment:Splign:2.1.0"
     exon            679..819
                     /gene="Itgbl1"
                     /inference="alignment:Splign:2.1.0"
     exon            820..960
                     /gene="Itgbl1"
                     /inference="alignment:Splign:2.1.0"
     exon            961..1107
                     /gene="Itgbl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1108..1224
                     /gene="Itgbl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1225..1371
                     /gene="Itgbl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1372..1485
                     /gene="Itgbl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1486..2289
                     /gene="Itgbl1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgctggtgac acttcttcct cctgctgcct cgggtggaag ccccagctag cagcagtgca
       61 gctggtctgc cctcccgcct gtacagctca gcatgcatcc cccaggcttt aagaacttct
      121 tgttgctggt gtcctccctt ttcttcattg ggctgtcagc tgcacctcaa agcttctcac
      181 catctctgag aagcctgtcg ggcgccccct gcaggctgtc ccgggcagag tccgagcgca
      241 gatgtcgtgc acctgggcag cccccaggga gcgctctgtg ccatgaccgt ggccggtgcg
      301 agtgtggggt gtgcatctgt cacgtgactg aacctggcac ctactttggg ccactgtgtg
      361 agtgccatga ctgggtctgc gagacctacg acgggaaaac ctgtgcaggc cacggtactt
      421 gtgactgcgg caagtgtaag tgtgatgtgg gatggtctgg ggaagcttgc cagtacccga
      481 ccaagtgcga cctgaccaaa aaaataagca accagatgtg caagaactct caagatgtca
      541 tctgctccaa cgcaggtaca tgtcactgtg gcaggtgtaa gtgtgataat tcagatggac
      601 atggactcat ttacggtaaa ttttgtgagt gtgatgatag agaatgcata gatgatgaaa
      661 cagaagaaat atgtggaggc catgggaagt gttactgtgg aaactgttac tgcgaggctg
      721 gttggcatgg agataaatgc gagttccagt gtgacatcac cccctgggaa agcaagcgaa
      781 gatgcacatc tccagatggc aaagtctgta gcaacagagg aacatgtgta tgtggtgaat
      841 gttcttgcca tgatgttgat ccaactggcg actggggaga cattcatgga gacacatgcg
      901 agtgtgatga aagggactgc agagctgttt atgatcgata ctctgatgat ttctgttcag
      961 gtcacgggca gtgtaactgt ggaagatgtg actgcagagc aggctggtat gggaagaagt
     1021 gtgagcaccc aaagaactgc ccattgtcag ctgaggagag caccagaaag tgccagggta
     1081 gctctgatct gccttgttct ggaaggggca gatgcgaatg tggcagatgt acctgttacc
     1141 ctcccgggga cagcagagta tatggcaaga cctgtgagtg tgatgaccgg cgctgtgaag
     1201 acctagacgg tgtggtctgt ggaggccgtg gcacgtgctc ctgtggtcgt tgtgtttgtg
     1261 agaaaggatg gtttggtaag ctctgccaac accctcggaa gtgtaatatg accgaagaac
     1321 aaagcaggag tctgtgtgag tcagcagatg gcacattgtg ctcggggaag ggttcttgtc
     1381 attgtggaaa gtgcatttgt tctggagaag agtggtatat ttcaggggag ttttgtgact
     1441 gtgatgacag agactgtgac aaacacgacg gtctcatttg cacagggaat ggaatctgta
     1501 gctgtggaaa ctgtgaatgc tgggatggat ggaatggaaa tgcatgtgaa atctggcttg
     1561 gtaccgaata tccttaatga tgccaaggga gacaactgga ttcttatttc taggccattt
     1621 tagaaattca gaggaaagca tgttacacag cactaggaca gacttttgtg tatttttcta
     1681 tttctgactg cccaagtgaa gcatgggtct tcattagaaa tgaatttagc aaactgatgt
     1741 aagttacacc ataaagaatt gttctcccat gactaatatc agtgtttcac aactgaagag
     1801 gacaattttg taacgcacaa gacaattggt ggtgtctaca gagaatttgg ttgtcagact
     1861 tggtaggtag gagtatttgt gttatgggaa tattagaggt agtgaccaca gacaatgctg
     1921 aacaccctac agaacataga aaggccctta caacaaagta ttttctgaca tccaatgttt
     1981 aacaagatgt agtagaaaaa tgctaagtct catggtattt tgtactccac atcccaaaac
     2041 cagaaacact gtatcagaat ataaggataa tatttattct cacataaacc aaccagtcag
     2101 atttttccag gattccatat gactctgaaa ttgtatatgg aatgataatg acagacacat
     2161 atgaggtgta atgatgtagg ctgggggctt accagatcac aagggcttta aactcacaag
     2221 aatctcttac aggaagaaat gaaaaatgca caatttgaca ttttaataaa taatgacata
     2281 agttgtttaa aaaaaaaaaa aaaaaaaaaa aaaa
//
