LOCUS       NM_001106719            1361 bp    mRNA    linear   ROD 26-OCT-2024
DEFINITION  Rattus norvegicus integrin subunit beta 1 binding protein 1
            (Itgb1bp1), transcript variant 1, mRNA.
ACCESSION   NM_001106719 XM_001070826 XM_216677
VERSION     NM_001106719.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1361)
  AUTHORS   Calderwood,D.A., Campbell,I.D. and Critchley,D.R.
  TITLE     Talins and kindlins: partners in integrin-mediated adhesion
  JOURNAL   Nat Rev Mol Cell Biol 14 (8), 503-517 (2013)
   PUBMED   23860236
  REMARK    Review article
REFERENCE   2  (bases 1 to 1361)
  AUTHORS   Bouvard,D., Pouwels,J., De Franceschi,N. and Ivaska,J.
  TITLE     Integrin inactivators: balancing cellular functions in vitro and in
            vivo
  JOURNAL   Nat Rev Mol Cell Biol 14 (7), 430-442 (2013)
   PUBMED   23719537
  REMARK    Review article
REFERENCE   3  (bases 1 to 1361)
  AUTHORS   Brutsch,R., Liebler,S.S., Wustehube,J., Bartol,A., Herberich,S.E.,
            Adam,M.G., Telzerow,A., Augustin,H.G. and Fischer,A.
  TITLE     Integrin cytoplasmic domain-associated protein-1 attenuates
            sprouting angiogenesis
  JOURNAL   Circ Res 107 (5), 592-601 (2010)
   PUBMED   20616313
REFERENCE   4  (bases 1 to 1361)
  AUTHORS   Millon-Fremillon,A., Bouvard,D., Grichine,A., Manet-Dupe,S.,
            Block,M.R. and Albiges-Rizo,C.
  TITLE     Cell adaptive response to extracellular matrix density is
            controlled by ICAP-1-dependent beta1-integrin affinity
  JOURNAL   J Cell Biol 180 (2), 427-441 (2008)
   PUBMED   18227284
REFERENCE   5  (bases 1 to 1361)
  AUTHORS   Beraud-Dufour,S., Gautier,R., Albiges-Rizo,C., Chardin,P. and
            Faurobert,E.
  TITLE     Krit 1 interactions with microtubules and membranes are regulated
            by Rap1 and integrin cytoplasmic domain associated protein-1
  JOURNAL   FEBS J 274 (21), 5518-5532 (2007)
   PUBMED   17916086
REFERENCE   6  (bases 1 to 1361)
  AUTHORS   Fournier,H.N., Dupe-Manet,S., Bouvard,D., Luton,F., Degani,S.,
            Block,M.R., Retta,S.F. and Albiges-Rizo,C.
  TITLE     Nuclear translocation of integrin cytoplasmic domain-associated
            protein 1 stimulates cellular proliferation
  JOURNAL   Mol Biol Cell 16 (4), 1859-1871 (2005)
   PUBMED   15703214
REFERENCE   7  (bases 1 to 1361)
  AUTHORS   Bouvard,D., Vignoud,L., Dupe-Manet,S., Abed,N., Fournier,H.N.,
            Vincent-Monegat,C., Retta,S.F., Fassler,R. and Block,M.R.
  TITLE     Disruption of focal adhesions by integrin cytoplasmic
            domain-associated protein-1 alpha
  JOURNAL   J Biol Chem 278 (8), 6567-6574 (2003)
   PUBMED   12473654
REFERENCE   8  (bases 1 to 1361)
  AUTHORS   Fournier,H.N., Dupe-Manet,S., Bouvard,D., Lacombe,M.L., Marie,C.,
            Block,M.R. and Albiges-Rizo,C.
  TITLE     Integrin cytoplasmic domain-associated protein 1alpha (ICAP-1alpha)
            interacts directly with the metastasis suppressor nm23-H2, and both
            proteins are targeted to newly formed cell adhesion sites upon
            integrin engagement
  JOURNAL   J Biol Chem 277 (23), 20895-20902 (2002)
   PUBMED   11919189
REFERENCE   9  (bases 1 to 1361)
  AUTHORS   Degani,S., Balzac,F., Brancaccio,M., Guazzone,S., Retta,S.F.,
            Silengo,L., Eva,A. and Tarone,G.
  TITLE     The integrin cytoplasmic domain-associated protein ICAP-1 binds and
            regulates Rho family GTPases during cell spreading
  JOURNAL   J Cell Biol 156 (2), 377-387 (2002)
   PUBMED   11807099
REFERENCE   10 (bases 1 to 1361)
  AUTHORS   Chang,D.D., Wong,C., Smith,H. and Liu,J.
  TITLE     ICAP-1, a novel beta1 integrin cytoplasmic domain-associated
            protein, binds to a conserved and functionally important NPXY
            sequence motif of beta1 integrin
  JOURNAL   J Cell Biol 138 (5), 1149-1157 (1997)
   PUBMED   9281591
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC169104.1.
            
            On Sep 4, 2008 this sequence version replaced NM_001106719.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC169104.1, SRR8487231.39552.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760434, SAMEA5760476
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1361
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q16"
     gene            1..1361
                     /gene="Itgb1bp1"
                     /note="integrin subunit beta 1 binding protein 1"
                     /db_xref="GeneID:298914"
                     /db_xref="RGD:1307810"
     exon            1..188
                     /gene="Itgb1bp1"
                     /inference="alignment:Splign:2.1.0"
     exon            189..217
                     /gene="Itgb1bp1"
                     /inference="alignment:Splign:2.1.0"
     exon            218..346
                     /gene="Itgb1bp1"
                     /inference="alignment:Splign:2.1.0"
     CDS             275..877
                     /gene="Itgb1bp1"
                     /codon_start=1
                     /product="integrin beta-1-binding protein 1"
                     /protein_id="NP_001100189.1"
                     /db_xref="GeneID:298914"
                     /db_xref="RGD:1307810"
                     /translation="MFRKGKKRHSSSSSQSSEISTKSKSVDSSLGGLSRSSTVASLDT
                     DSTKSSGQSNSNLDTCAEFRIKYVGAIEKLAVSEGKSLEGPLDLINYIDVAQQDGKLP
                     FVPMEEEFILGVSKYGIKVSTMDQHGVLHRHALYLIIRMVCYDDGLGAGKSLLALKTT
                     DASNEEYSLWVYQCNSLEQAQAICKVLSTAFDSVLTSDKS"
     exon            347..425
                     /gene="Itgb1bp1"
                     /inference="alignment:Splign:2.1.0"
     exon            426..562
                     /gene="Itgb1bp1"
                     /inference="alignment:Splign:2.1.0"
     exon            563..655
                     /gene="Itgb1bp1"
                     /inference="alignment:Splign:2.1.0"
     exon            656..805
                     /gene="Itgb1bp1"
                     /inference="alignment:Splign:2.1.0"
     exon            806..1329
                     /gene="Itgb1bp1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggagggacc cgtgttcctg agagaggtct actgcctgcc tgcccgggga ccaggctccg
       61 caaaagcctg aggcctctct ctgatggctg ctgcaccgtt ggggttggag ttagcggtct
      121 acatcctcac ttgtgcgagg catatgtgcg gagagctttg gaagcctgat cttgtcggga
      181 tccccaaagg cccagtgttc agcctgagga ggactggtac tggagacaac acttcttcca
      241 ctgggcaact tctctgacca agctatggtg aaagatgttt cgcaaaggca agaagagaca
      301 cagcagcagc agttcccaga gcagtgaaat cagtacaaag agcaagtctg tggattccag
      361 ccttggaggg ctttcaagat ccagcactgt cgccagcctc gatacagact ccactaaaag
      421 ctcaggacaa agtaacagca atttagacac gtgtgctgag ttccgaataa agtacgttgg
      481 tgccatcgag aaactggctg tgtctgaggg gaagagcctc gaaggaccac tagacctgat
      541 aaattacata gatgtcgccc agcaagatgg aaagttacct tttgttccca tggaagagga
      601 gtttattctg ggcgtttcta agtacggcat aaaagtctcg accatggatc agcatggtgt
      661 tctgcatagg catgccctgt atttaatcat ccggatggtg tgttacgatg atggcctggg
      721 agccgggaag agcttgctgg cactcaagac caccgatgca agcaatgaag aatacagcct
      781 gtgggtttac cagtgtaaca gcctggaaca agcccaagca atctgcaagg tcttatccac
      841 agcgtttgac tccgtgttga cctctgacaa gtcctgaact ctgcagacaa gtggaaactg
      901 acccattgag agctcacctt ttcctgcatc cgtctgcagc catagactgt tagagggtgt
      961 aaaacttgac ccagttttct aaagtgtaat ttataaaata ttggtcttgt actaaaaggt
     1021 gtcgttaaca gtaggtcaac gtccaataaa ttacctgctt tctggactaa agagaaacct
     1081 tggggtcggg acaaacggcc tggtacttaa gagcatttgc agagggttca gttctcagca
     1141 ccaatatggt ggctcaaaag tgcctgtaac tccagttcca ggagatccga cctcctcttc
     1201 tggcttcctt aggtaccagg catacatgtg gtgtacatac atacatacat acatacatac
     1261 atacatacat gcatgcatac atgcagccac tcacctgtac acataaaaat aaaatctaag
     1321 aaagataaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
//
