LOCUS       NM_001413793            5492 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus integrin subunit alpha 11 (Itga11), mRNA.
ACCESSION   NM_001413793 XM_039081493
VERSION     NM_001413793.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5492)
  AUTHORS   Sipila,K., Haag,S., Denessiouk,K., Kapyla,J., Peters,E.C.,
            Denesyuk,A., Hansen,U., Konttinen,Y., Johnson,M.S., Holmdahl,R. and
            Heino,J.
  TITLE     Citrullination of collagen II affects integrin-mediated cell
            adhesion in a receptor-specific manner
  JOURNAL   FASEB J 28 (8), 3758-3768 (2014)
   PUBMED   24823363
REFERENCE   2  (bases 1 to 5492)
  AUTHORS   Talior-Volodarsky,I., Connelly,K.A., Arora,P.D., Gullberg,D. and
            McCulloch,C.A.
  TITLE     alpha11 integrin stimulates myofibroblast differentiation in
            diabetic cardiomyopathy
  JOURNAL   Cardiovasc Res 96 (2), 265-275 (2012)
   PUBMED   22869616
  REMARK    GeneRIF: Interactions between alpha11 integrins and the
            Smad-dependent TGF-beta2 signalling may contribute to the formation
            of pro-fibrotic myofibroblasts and the development of a fibrotic
            interstitium in diabetic cardiomyopathy.
REFERENCE   3  (bases 1 to 5492)
  AUTHORS   Kuo,J.C., Han,X., Hsiao,C.T., Yates,J.R. 3rd and Waterman,C.M.
  TITLE     Analysis of the myosin-II-responsive focal adhesion proteome
            reveals a role for beta-Pix in negative regulation of focal
            adhesion maturation
  JOURNAL   Nat Cell Biol 13 (4), 383-393 (2011)
   PUBMED   21423176
REFERENCE   4  (bases 1 to 5492)
  AUTHORS   Ji,H., Long,V., Briody,V. and Chien,E.K.
  TITLE     Progesterone modulates integrin {alpha}2 (ITGA2) and {alpha}11
            (ITGA11) in the pregnant cervix
  JOURNAL   Reprod Sci 18 (2), 156-163 (2011)
   PUBMED   20959644
  REMARK    GeneRIF: Integrin alpha11 (ITGA11) expression increased through
            mid-gestation, peaking on day 18 and decreasing through day 22
REFERENCE   5  (bases 1 to 5492)
  AUTHORS   Jones,S., Zhang,X., Parsons,D.W., Lin,J.C., Leary,R.J.,
            Angenendt,P., Mankoo,P., Carter,H., Kamiyama,H., Jimeno,A.,
            Hong,S.M., Fu,B., Lin,M.T., Calhoun,E.S., Kamiyama,M., Walter,K.,
            Nikolskaya,T., Nikolsky,Y., Hartigan,J., Smith,D.R., Hidalgo,M.,
            Leach,S.D., Klein,A.P., Jaffee,E.M., Goggins,M., Maitra,A.,
            Iacobuzio-Donahue,C., Eshleman,J.R., Kern,S.E., Hruban,R.H.,
            Karchin,R., Papadopoulos,N., Parmigiani,G., Vogelstein,B.,
            Velculescu,V.E. and Kinzler,K.W.
  TITLE     Core signaling pathways in human pancreatic cancers revealed by
            global genomic analyses
  JOURNAL   Science 321 (5897), 1801-1806 (2008)
   PUBMED   18772397
REFERENCE   6  (bases 1 to 5492)
  AUTHORS   Takada,Y., Ye,X. and Simon,S.
  TITLE     The integrins
  JOURNAL   Genome Biol 8 (5), 215 (2007)
   PUBMED   17543136
  REMARK    Review article
REFERENCE   7  (bases 1 to 5492)
  AUTHORS   Foster,L.J., Zeemann,P.A., Li,C., Mann,M., Jensen,O.N. and
            Kassem,M.
  TITLE     Differential expression profiling of membrane proteins by
            quantitative proteomics in a human mesenchymal stem cell line
            undergoing osteoblast differentiation
  JOURNAL   Stem Cells 23 (9), 1367-1377 (2005)
   PUBMED   16210410
REFERENCE   8  (bases 1 to 5492)
  AUTHORS   Popova,S.N., Rodriguez-Sanchez,B., Liden,A., Betsholtz,C., Van Den
            Bos,T. and Gullberg,D.
  TITLE     The mesenchymal alpha11beta1 integrin attenuates PDGF-BB-stimulated
            chemotaxis of embryonic fibroblasts on collagens
  JOURNAL   Dev Biol 270 (2), 427-442 (2004)
   PUBMED   15183724
REFERENCE   9  (bases 1 to 5492)
  AUTHORS   Hynes,R.O.
  TITLE     Integrins: bidirectional, allosteric signaling machines
  JOURNAL   Cell 110 (6), 673-687 (2002)
   PUBMED   12297042
  REMARK    Review article
REFERENCE   10 (bases 1 to 5492)
  AUTHORS   Tiger,C.F., Fougerousse,F., Grundstrom,G., Velling,T. and
            Gullberg,D.
  TITLE     alpha11beta1 integrin is a receptor for interstitial collagens
            involved in cell migration and collagen reorganization on
            mesenchymal nonmuscle cells
  JOURNAL   Dev Biol 237 (1), 116-129 (2001)
   PUBMED   11518510
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Nov 9, 2022 this sequence version replaced XM_039081493.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643429.30674.1,
                                           SRR26643290.29628.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-142               JAXUCZ010000008.1  72041432-72041573
            143-254             JAXUCZ010000008.1  72057910-72058021
            255-355             JAXUCZ010000008.1  72088619-72088719
            356-447             JAXUCZ010000008.1  72093152-72093243
            448-562             JAXUCZ010000008.1  72094011-72094125
            563-690             JAXUCZ010000008.1  72097099-72097226
            691-839             JAXUCZ010000008.1  72099652-72099800
            840-984             JAXUCZ010000008.1  72106144-72106288
            985-1150            JAXUCZ010000008.1  72106705-72106870
            1151-1221           JAXUCZ010000008.1  72108313-72108383
            1222-1366           JAXUCZ010000008.1  72113747-72113891
            1367-1515           JAXUCZ010000008.1  72114520-72114668
            1516-1656           JAXUCZ010000008.1  72118429-72118569
            1657-1860           JAXUCZ010000008.1  72118828-72119031
            1861-1991           JAXUCZ010000008.1  72120953-72121083
            1992-2158           JAXUCZ010000008.1  72123466-72123632
            2159-2301           JAXUCZ010000008.1  72124710-72124852
            2302-2412           JAXUCZ010000008.1  72126003-72126113
            2413-2498           JAXUCZ010000008.1  72129133-72129218
            2499-2706           JAXUCZ010000008.1  72130708-72130915
            2707-2805           JAXUCZ010000008.1  72134666-72134764
            2806-2882           JAXUCZ010000008.1  72135246-72135322
            2883-2972           JAXUCZ010000008.1  72136985-72137074
            2973-3063           JAXUCZ010000008.1  72138665-72138755
            3064-3177           JAXUCZ010000008.1  72140136-72140249
            3178-3264           JAXUCZ010000008.1  72140416-72140502
            3265-3375           JAXUCZ010000008.1  72142344-72142454
            3376-3471           JAXUCZ010000008.1  72142594-72142689
            3472-3585           JAXUCZ010000008.1  72147648-72147761
            3586-5492           JAXUCZ010000008.1  72148231-72150137
FEATURES             Location/Qualifiers
     source          1..5492
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..5492
                     /gene="Itga11"
                     /note="integrin subunit alpha 11"
                     /db_xref="GeneID:315744"
                     /db_xref="RGD:1311711"
     exon            1..142
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     CDS             91..3657
                     /gene="Itga11"
                     /note="integrin, alpha 11; integrin alpha-11-like"
                     /codon_start=1
                     /product="integrin alpha-11 precursor"
                     /protein_id="NP_001400722.1"
                     /db_xref="GeneID:315744"
                     /db_xref="RGD:1311711"
                     /translation="MDLPRGFLVAWTLSLWPGFTDTFNMDTRNPRVIAGPSAAFFGYT
                     VQQHDISGKKWLVVGAPLETNGHQKTGDVYKCPVTQGNCTKLNLGRVTLSNVSERKDN
                     MRLGLSLATNPKDSSFLACSPLWSHECGSSYYTTGMCSRVNSNFRFSKTVAPALQRCQ
                     TYMDIVIVLDGSNSIYPWVEVQHFLIEILTKFYIGPGQIQVGIVQYGEDAVHEFHLND
                     YKSVKDVVEAASHIEQRGGTETRTAFGIEFARSEAFQKGGRKGAKKVMIVITDGESHD
                     SPDLEKVIRQSEKDNVTRYAVAVLGYYNRRGINPETFLNEIKYIASDPDDKHFFNVTD
                     EAALKDIVDALGDRIFSLEGTNKNETSFGLEMSQTGFSSHVVEDGVLLGAVGAYDWNG
                     AVLKETSAGKVIPLRESYLKEFPEELKNHAAYLGYTVTSVVSSKQGRVYVAGAPRFNH
                     TGKVILFSIHTNRSLTIHQALRGEQIGSYFGSEITSVDINNDRVTDVLLVGAPMYFSE
                     GRERGKVYVYNLRQNRFVFNGTLKDSHSYQNARFGSCIASVQDLNQDSYNDVVVGAPL
                     EDSHRGAIYIFHGFQTNILKKPVQRISASELAPGLQHFGCSIHGQLDLNEDGLVDLAV
                     GALGNAVVLWARPVVQINASLHFEPSKINIFHKDCKRNGRDATCLAAFLCFGPIFLAP
                     HFHTATVGIRYNATMDERRYMPRAHLDEGADQFTNRAVLLSSGQEHCQRINFHVLDTA
                     DYVKPVAFSVEYSLEDPDHGPMLDNGWPTTLRVSVPFWNGCNEDEHCVPDLVLDARSD
                     LPTAMEYCQQVLRRPAQDCSSYTLSFDTTVFIIESTRRRVAVEATLENRGENAYSAVL
                     NISQSENLQFASLIQKDDSDNSIECVNEERRLHKKVCNVSYPFFRAKAKVAFRLDFEF
                     SKSVFLHHLQIHLGAGSDSHEQDSTADDNTALLRFHLKYEADVLFTRSSSLSHFEVKA
                     NSSLESYDGIGPPFNCVFKVQNLGFFPIHGVMMKITVPIATRGGNRLLMLKDFFTDQV
                     NTSCNIWGNSTEYRSTPTEEDLSHAPQRNHSNSDVVSIICNVRLAPNQETSFYLVGNL
                     WLMSLKALKYRSMKITVNAALQRQFHSPFIFREEDPSRQVTFEISKQEDWQVPIWIIV
                     GSSLGGLLLLALLVLALWKLGFFKSAKRKREPSLGPVPKELE"
     exon            143..254
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            255..355
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            356..447
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            448..562
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            563..690
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            691..839
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            840..984
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            985..1150
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            1151..1221
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            1222..1366
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            1367..1515
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            1516..1656
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            1657..1860
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            1861..1991
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            1992..2158
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            2159..2301
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            2302..2412
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            2413..2498
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            2499..2706
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            2707..2805
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            2806..2882
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            2883..2972
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            2973..3063
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            3064..3177
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            3178..3264
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            3265..3375
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            3376..3471
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            3472..3585
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
     exon            3586..5492
                     /gene="Itga11"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctggctcag gacgctgcgc tcgaaccgag gctgtcgctc tggctctcag ccccgcgacc
       61 atcgcgacac cctctgcctc acagcgggcc atggacttgc ccaggggctt cctggtggcc
      121 tggaccctca gcctctggcc aggattcacg gacaccttca acatggatac caggaatccc
      181 cgggtcatcg ctggtcccag tgctgctttc tttggctaca cagtacagca gcacgatatc
      241 agtggcaaga agtggttggt tgtgggtgcc ccactggaaa ccaatggcca ccagaagaca
      301 ggagatgtat acaagtgtcc agtaacccag ggcaactgca ccaaactcaa cctgggcagg
      361 gtcactctgt ccaatgtgtc tgagaggaag gacaacatgc gcctcggcct gagccttgcc
      421 accaacccca aggacagcag cttcctggcc tgcagccctc tctggtcaca cgagtgtgga
      481 agctcctact acaccactgg catgtgctcc cgggtcaact ccaacttcag attctccaag
      541 acggtggccc cggcacttca gaggtgccag acttatatgg acattgtcat tgtcttggac
      601 ggctccaaca gcatctaccc ctgggtggag gtccaacact tcctcatcga gatcctgaca
      661 aagttctaca tcggccctgg ccagatccag gtcggaatag ttcagtatgg agaagatgcc
      721 gtccatgagt tccaccttaa cgactacaaa tctgtaaaag atgtggtgga agccgccagc
      781 cacattgaac agagaggagg gactgaaacc cgcacggcat ttggcattga atttgcacgc
      841 tcagaggctt tccagaaggg cggaaggaaa ggggccaaga aagtaatgat tgtcatcacg
      901 gacggggaat cccacgacag cccagacctg gagaaggtga tccggcaaag cgagaaggac
      961 aacgtgacca gatacgctgt ggccgtcttg ggctactaca accgcagggg gatcaatcca
     1021 gagacttttc taaacgaaat caaatacatc gccagtgacc ctgacgacaa gcatttcttc
     1081 aatgtcacgg atgaggcggc cttgaaggac attgttgatg cccttgggga caggatcttc
     1141 agcttggaag gcaccaacaa gaatgaaacc tcttttggtc tggagatgtc gcagaccggc
     1201 ttttcctcgc atgtggtaga ggatggggtc ctgctgggag ctgtgggagc ctatgactgg
     1261 aacggggcag tgctgaagga gacaagtgca ggaaaggtga ttcctctccg agagtcctac
     1321 cttaaggagt tcccggagga gttgaagaac cacgccgcat acctagggta cacggtgaca
     1381 tcggttgtgt cctccaagca ggggcgcgtg tatgtggctg gagcccccag gttcaaccat
     1441 actggcaagg tcattctgtt cagtatacac accaaccgga gcctcaccat ccaccaggct
     1501 cttcggggcg agcagatagg ctcctacttc gggagtgaga tcacctcggt ggacatcaat
     1561 aatgacagag tgacagatgt cctgctggtg ggcgcaccca tgtacttcag cgagggccga
     1621 gagagaggca aggtgtatgt ctacaacctg agacagaacc ggtttgtttt taatggcact
     1681 ctgaaggatt cccacagcta ccagaacgcc cggttcgggt catgcattgc ctccgttcaa
     1741 gacctcaacc aagattccta caatgacgtg gtggtggggg cccctctgga ggacagccac
     1801 agaggggcca tctacatctt ccatggcttc caaaccaaca tcctgaagaa gcccgtgcag
     1861 agaatatcag cctcagagct ggctcccggc ttgcagcatt ttggctgcag catccacgga
     1921 caactggacc tcaatgagga cgggcttgtg gacctagcag tgggcgccct gggcaacgct
     1981 gtggttttgt gggcgcgtcc cgtagttcag atcaacgcca gcctccactt tgagccttcc
     2041 aagatcaaca tcttccacaa ggactgcaag cgcaatggca gggatgccac ctgcctggct
     2101 gccttcctct gcttcggacc tatcttcctg gcaccccact tccacacagc aaccgtcggc
     2161 atcaggtaca atgcaaccat ggatgagaga cggtatatgc cacgggcaca tctggatgag
     2221 ggtgcagacc agttcaccaa cagggctgtc ctactctctt ctggtcagga acactgtcaa
     2281 aggatcaact tccacgtcct ggacactgcc gactacgtga agccagtggc cttctctgtg
     2341 gaatattccc tagaggaccc tgaccatggc cccatgctgg acaacggctg gcccactaca
     2401 ctcagagtgt cggtgccctt ctggaatggc tgtaatgagg atgaacactg tgtccctgac
     2461 cttgtactgg atgctcgaag tgatctgccc actgccatgg agtactgcca acaggtgctg
     2521 aggaggccgg cccaggactg ctccagttac acactgtcct tcgacaccac tgtcttcatc
     2581 atagagagca cacggcgccg ggtagcagta gaggccacgc tggagaacag aggagagaat
     2641 gcttacagtg cagtcctcaa tatctcccag tcagagaacc tgcagtttgc cagcctgatc
     2701 cagaaggatg actcagacaa cagcatcgag tgtgtgaatg aggagaggcg gctacacaag
     2761 aaagtctgca acgtcagtta ccccttcttc agggccaagg ccaaggtggc tttccggctg
     2821 gatttcgagt tcagcaagtc tgtgttcctg caccatcttc agatccatct gggtgccggc
     2881 agcgacagtc acgagcagga cagcaccgca gatgacaaca cggccctcct tcgcttccac
     2941 ctcaaatatg aagcagacgt cctctttacc agaagcagca gcctgagcca cttcgaggtc
     3001 aaggccaaca gctcgctgga gagctatgat ggcatcgggc ctccattcaa ctgtgttttc
     3061 aaggtgcaga acctgggctt tttccccatc cacggggtga tgatgaagat tactgtgccc
     3121 attgccacca ggggtggcaa ccgcctgctg atgctgaagg acttcttcac agaccaggtc
     3181 aacacatcct gtaacatctg ggggaacagc acagagtacc ggagtacccc aactgaggaa
     3241 gacctgagcc atgccccaca gaggaatcac agcaactccg atgtggtctc catcatctgc
     3301 aatgtgagac tagcccccaa ccaggagacc agcttctacc tggtggggaa cctgtggctg
     3361 atgtccctga aagcactcaa gtacaggtct atgaagatca cagtcaacgc cgccttgcag
     3421 aggcagttcc acagcccctt catcttccga gaggaggacc ccagtcgcca ggtcacgttt
     3481 gagatctcca agcaagaaga ctggcaggtc cccatctgga tcatcgtggg cagctctctg
     3541 ggaggcctct tgctgctggc cctgctggtc ctggcactgt ggaagcttgg tttctttaaa
     3601 agtgccaagc gcaagaggga gcccagcctg ggccccgtcc ccaaagagct ggagtgagga
     3661 tccagaggaa gcttcaagtt gatgggggcc agacaccagt ccaggggtgt gtgggcccag
     3721 gcctgtggcc tcacagagct ggagcaaaga ggacacccgt ggacttttgc attgagctcg
     3781 tctctggaac gatggtaact gatccctgtg ggatggacct caagcccgtg tccagagcaa
     3841 cttctctact agaggttatg acgcttccag tacagatccc taaagactaa aagggaccct
     3901 tcgaagcctt cccccaaggc tccgtggagg caatctgctg ccccaaacac taaggtgcta
     3961 gggttgtttt tatcttgccc acttctgaag aaacgcaagg ggaagctagc aaatacacgc
     4021 ccactgtaca cgccctatct agacctagag tttcaggact ccaaggcccg cagcataaca
     4081 tccccacctc tcacccctgc tcttggttcc caagcacaga catcccttct ccatagatag
     4141 atcccaaaga tctccatgag tgaacgagag ttgtgtggct tgatatgaca gctgcaggcc
     4201 aatggtggaa acgcatccag ggactgtgcc agatggtcag gtgggaacca ggatgctggg
     4261 tacctccgga acatcggaac atcggaaagc ggtagagctc tccagcagta accaccaccc
     4321 actcactcct gctctcctgc ctcccccgca gctcctctca gcagctttgg ttgctaggca
     4381 actcatgcta ggaagtctga agatgataaa aatctgtggc tctccatacc cacttgtctg
     4441 acaactgcag cttgtccctg gcaggcgcac tgtggttgga agcctctgtt ctttgcatca
     4501 cacacaaaca cacacacaca cacacacaca cacacataca cacacgcccc cgtgcgtgca
     4561 cacacacacg cgcacacacg catgcatgca tgcacacgca ctcacgtgca cccatatact
     4621 catacacctc ccaggcacta atgcgtgggg gaagggctcc tgtggaggcg ctgtacagag
     4681 gccttcttgg catgcactga acaaatccca tgcaaggcca ctcagaacct taaacctcag
     4741 aggcagatag gcatctcact ggccagctct cgggacaagc cccaaggaca aggggcatgt
     4801 cggatgccca gcagagtaat ttatgcctta accctttgtt gagatggaaa tcgtcagatc
     4861 aatgttccct tgtcatctgt ttcatctgaa caatgtcatc tgttcccctg tgcagtacga
     4921 cctttactgt cagaaatata tttaagaaaa tgttctaaaa ggtattttaa aacaaccaac
     4981 aacagacatt ccactctgtg acaaagcaag gctgcattct gtgacaaagc aaggctgcat
     5041 tctgttttaa agaggaaagg gaggggggtt ggggatttgg ctcagtggta gagcgcttgc
     5101 ctagcaagcg caaggccctg ggttcagtcc ccagctccga aaaaaaagaa gaaaaaagaa
     5161 aaaaaaagag gaaagggagg agggtgtctg ctcatatcta aatgttgggg tcagtcttgt
     5221 ccatgacata gccatctctc tcccaaggtc tacccggcct ctcttgctcc gacatctctg
     5281 catcttggta gtggtgcact gctcgcccac catcatcacc acctttggcc aggggctccc
     5341 tcactcaggt tcccagaccc tccaggctgg cccttcagtg tcaaccctcc cacacactga
     5401 cttagagaga gaccactctt ggacacaagc atctccattc tatgcttgta ctggtaattc
     5461 atttttcaga accctaacaa ataatttaga aa
//
