LOCUS       NM_001401000            2203 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus intestine-specific homeobox (Isx), transcript
            variant 1, mRNA.
ACCESSION   NM_001401000 XM_008772332
VERSION     NM_001401000.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2203)
  AUTHORS   Widjaja-Adhi,M.A., Lobo,G.P., Golczak,M. and Von Lintig,J.
  TITLE     A genetic dissection of intestinal fat-soluble vitamin and
            carotenoid absorption
  JOURNAL   Hum Mol Genet 24 (11), 3206-3219 (2015)
   PUBMED   25701869
REFERENCE   2  (bases 1 to 2203)
  AUTHORS   Seino,Y., Miki,T., Kiyonari,H., Abe,T., Fujimoto,W., Kimura,K.,
            Takeuchi,A., Takahashi,Y., Oiso,Y., Iwanaga,T. and Seino,S.
  TITLE     Isx participates in the maintenance of vitamin A metabolism by
            regulation of beta-carotene 15,15'-monooxygenase (Bcmo1) expression
  JOURNAL   J Biol Chem 283 (8), 4905-4911 (2008)
   PUBMED   18093975
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000019.1.
            
            On Feb 1, 2022 this sequence version replaced XM_008772332.2.
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1132              JAXUCZ010000019.1  13223385-13224516
            1133-1284           JAXUCZ010000019.1  13241893-13242044
            1285-1360           JAXUCZ010000019.1  13243793-13243868
            1361-2203           JAXUCZ010000019.1  13244659-13245501
FEATURES             Location/Qualifiers
     source          1..2203
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19p11"
     gene            1..2203
                     /gene="Isx"
                     /note="intestine-specific homeobox"
                     /db_xref="GeneID:682968"
                     /db_xref="RGD:1592776"
     exon            1..1132
                     /gene="Isx"
                     /inference="alignment:Splign:2.1.0"
     CDS             916..1644
                     /gene="Isx"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="intestine-specific homeobox isoform 1"
                     /protein_id="NP_001387929.1"
                     /db_xref="GeneID:682968"
                     /db_xref="RGD:1592776"
                     /translation="MAGPTIQRDIEKSSGYCEAPEKLGLSFSIEAILKRPTERRNLPR
                     PQSIGGGDSRQTTTSGSKLEKPTQDQPQEERKNKRRVRTTFTTEQLQELEKLFHFTHY
                     PDIHVRSQLASRINLPEARVQIWFQNQRAKWRKQEKSGSLSAPQQPGSCTDAHCSAHI
                     GATHRMLPPLSDSARFKLVPCPDSPCPMAPMGPAAPAWPSHPAALCPYLHPPTPKPQV
                     GQHLCNANIRTGFSLPKQATLLPQ"
     exon            1133..1284
                     /gene="Isx"
                     /inference="alignment:Splign:2.1.0"
     exon            1285..1360
                     /gene="Isx"
                     /inference="alignment:Splign:2.1.0"
     exon            1361..2203
                     /gene="Isx"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acacatttct ttgaacggaa ttcctggcaa gatagagcag tgactgtcag ctccgagcct
       61 ggagtttatt ggacagggcg tcttcggggc tgtctcagag acaggtaaag ggcaatcaag
      121 caggaaaaaa gtagaaagga ccccaaaaga aggagaaacg ggtgactaaa gaatttagta
      181 tgtgactgaa agttgggaag aggagaacag cataaagacc agtggagaag agtcagacca
      241 caggcctgag gtgaaagcaa gcacagacct ggcagtgacc cagaatcgtc cttaacctct
      301 gctgaagatc tgcagaggta caggagccct ggaagtctga ctcttgagac tggaagctga
      361 attgaggaag tccagaaggg cctctgagaa gaggctcagg gctcacttgg ccacgaagaa
      421 cccataggtg gcaccctagc ttcccaggga ctgcctgagg ccagcaggaa ggggacacga
      481 gtcagagaga ggacaaaggt ggatgctggc tccaaatctc taggcagtga tatcatccca
      541 ccaactccgc tgtttttttt ttctttcttt gttttctggt atccttgagc tcaggatctt
      601 tgcctaggct ggtgactgtg aaagcctcca cctccaagaa gaccctctct ggaaaacttg
      661 acctgtggag acaggacaag tacccaccag ctcttctgct aaaagccact ttctaatctt
      721 ggaggtgttc gaggtccatg gaagtccctg tgttcaagga attgtgccag agtcccccag
      781 catcaggatc tccaatcacc acctctgtgt gccctctggg tccccagaaa ctccagaaag
      841 aaaatatacc accttctgct ggcatcgccc caggcacaca cagagtgttc ctcccagcag
      901 ccttcagatc aggctatggc aggtcctacc atccagaggg acatagagaa gagttcagga
      961 tactgtgagg ccccagagaa gctgggcctg tctttctcca ttgaggcaat tctgaagaga
     1021 cccacagaaa gaagaaattt gcccagacca caaagcattg gtggtgggga ctccaggcag
     1081 acaactacct caggttctaa gttggagaag cccacacagg atcagcccca agaggaaaga
     1141 aagaacaagc ggagagttcg gactaccttc accacagagc agctacagga gctggagaag
     1201 ctcttccact tcacccacta ccccgacatc catgtccggt cccagctggc ttccaggatt
     1261 aacctgcccg aagctcgagt acagatctgg ttccagaatc agagggccaa gtggaggaag
     1321 caggagaaga gtgggagcct cagtgcccca cagcagcctg ggtcctgtac tgacgcccac
     1381 tgctctgccc acattggtgc cacccacaga atgctacctc ctctctcaga ctcagctcgc
     1441 ttcaagctgg ttccctgccc agattcccct tgtcccatgg cacccatggg acctgcagcc
     1501 cctgcctggc cctctcaccc agcagccttg tgtccctacc ttcatcctcc cacccccaaa
     1561 ccccaagtgg ggcagcatct gtgcaatgcc aacataagga ctggtttctc tcttcccaag
     1621 caagcaactc tcctccctca gtgatggccg acagccctgg acctcagaga aaatcacttc
     1681 cacagtccat caatggcccc cagctgagga agctacccag agcttgccat taaagactgt
     1741 accagccatg gatgacagcc aaggacagca cacatctcac caagtcagtc tcctagtgca
     1801 aaatcctggc tgactaaggg ctgggatgaa gctcagaata agctgctctc ttctcacccc
     1861 tcatctataa ctaagcagcc atttctatgg acccctttgc cccttattta agagagcctt
     1921 gggaaataca aggcatgggg ggagggctgc acattcatga acccatccgt atactcgttc
     1981 acaatgtcca cactgaacgc tgagcactgt gcacttgcaa acagatgttg ggctacacag
     2041 gtcagattct gcccaggtta gctgaaaggt gatcctaacc tctgcctgca aatggatgtt
     2101 ggtgacattg gactcagcta gtgtctagca cattcctaat gactttgata tgaaaaaaaa
     2161 atctcagaat gggagagaaa tagaagaaat tgttcttaat tta
//
