LOCUS       NM_001399427            4082 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus immunoglobulin superfamily containing
            leucine-rich repeat 2 (Islr2), mRNA.
ACCESSION   NM_001399427 XM_003750524
VERSION     NM_001399427.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4082)
  AUTHORS   Mandai,K., Guo,T., St Hillaire,C., Meabon,J.S., Kanning,K.C.,
            Bothwell,M. and Ginty,D.D.
  TITLE     LIG family receptor tyrosine kinase-associated proteins modulate
            growth factor signals during neural development
  JOURNAL   Neuron 63 (5), 614-627 (2009)
   PUBMED   19755105
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Jan 7, 2022 this sequence version replaced XM_003750524.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643293.45597.1, DV213828.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840110 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-287               JAXUCZ010000008.1  67509695-67509981   c
            288-418             JAXUCZ010000008.1  67508960-67509090   c
            419-4082            JAXUCZ010000008.1  67504042-67507705   c
FEATURES             Location/Qualifiers
     source          1..4082
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..4082
                     /gene="Islr2"
                     /note="immunoglobulin superfamily containing leucine-rich
                     repeat 2"
                     /db_xref="GeneID:100910729"
                     /db_xref="RGD:6497037"
     exon            1..287
                     /gene="Islr2"
                     /inference="alignment:Splign:2.1.0"
     exon            288..418
                     /gene="Islr2"
                     /inference="alignment:Splign:2.1.0"
     exon            419..4082
                     /gene="Islr2"
                     /inference="alignment:Splign:2.1.0"
     CDS             424..2664
                     /gene="Islr2"
                     /note="immunoglobulin superfamily containing leucine-rich
                     repeat protein 2-like"
                     /codon_start=1
                     /product="immunoglobulin superfamily containing
                     leucine-rich repeat protein 2 precursor"
                     /protein_id="NP_001386356.1"
                     /db_xref="GeneID:100910729"
                     /db_xref="RGD:6497037"
                     /translation="MMGPFGSLCLAWALLGVARACPEPCACVDKYAHQFADCAYKELR
                     EVPEGLPANVTTLSLSANKITVLRRGAFVNVTQVTSLWLAHSEVRTVESGALAVLSQL
                     KNLDLSHNLISNFPWSDLRNLSALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRL
                     RTLEPGTFDALSALSHLQLYHNPFHCSCGLVWLQAWAASTRVSLPEPDSIACASPPEL
                     QGVPVHRLPALPCAPPSVRLSAEPPPEAPGTPLRAGLSFLLHCVAEGHPTPRLQWQLQ
                     IPGGTVVLVPPVLSKEEDGGEKVDDGEGDGDEDQPTQTEAPTPTPAPAWPAPPATPRF
                     LALANGSLLVPLLSAKEAGIYTCRAHNELGTNSTSLRVTVAAAGPPKHAPGTGEEPDA
                     QAPTSERKATTKGRSNSVLPFKPEGKTKGQGLARVSILGETEAELEETDEEEQMGGQI
                     PADPMGEKHCGHGDPSRYVSNHAFNQSSDLKPHVFELGVIALDVAEREARVQLTPLAA
                     RWGPGPDGASGARRPGRRPLRLLYLCPAGGGTAVQWSRVEEGVNAYWFRGLRPGTNYS
                     VCLALAGEACHVQVVFSTKKELPSLLVIVTVSVFLLVLATVPLLGAACCHLLAKHPGK
                     PYRLILRPQAPDPMEKRIAADFDPRASYLESEKSYPARGEAGGEEPEEVPEEGLDEDV
                     EQGDPSGDLQREESLAACSLVESQSKANQEEFEAGSEYSDRLPLGAEAVNIAQEINGN
                     YRQTAG"
ORIGIN      
        1 tgaacgaggc ttcggggagg gggaggctag cagccggctg gaaggaaagg gtccgggaga
       61 gccaggcagc gcagttcagc aggtcccgct ggaggtcttt ctgtgcggct gcttgctttg
      121 gggaggaaaa aagtgtttaa aggcaaagac acgcccctcc agtcctatgc ctttctttct
      181 cccaaattcc tcaaagatgg tttgtctcac gtgttgcggg gcgtagaaag gatcgtattc
      241 agttaaaagc aaaagctcgc gggcgctggc gggacgggcg cgtgaggcaa cagatgccag
      301 aagcgccctt ggactgtcac ctgattctgg agaacggctt gcagtctgaa ggcggcacac
      361 tgcaggtcag agagcagcag gtaaacagtg gaaggacccc acaaccacag cccacaagga
      421 gccatgatgg ggccctttgg atccctttgt ttggcctggg ctttgctagg agtggccaga
      481 gcgtgtcccg agccttgtgc ctgtgttgac aagtacgccc accagtttgc agactgtgcc
      541 tacaaggagc tgcgcgaggt cccagaagga ctgccagcca acgtgaccac gcttagtctg
      601 tctgccaaca agattacggt attaaggcgg ggggccttcg tcaacgtcac gcaggtcact
      661 tcgctgtggc tggctcacag tgaggtgcgc accgtagagt caggggcatt ggcagtgctg
      721 agtcagctca agaacctcga cctaagccac aacctcatat ccaacttccc ttggagcgac
      781 cttcgtaacc tgagcgcgct gcagctgctg aaaatgaacc acaaccgcct gggatcgctg
      841 ccccgggatg cactcggcgc gctcccggac ctgcgctctc tgcgcatcaa caacaaccgg
      901 ctgcgtaccc tggagcccgg cacgttcgac gctctaagcg cgctgtctca cctgcaactc
      961 tatcacaacc ccttccactg cagctgtggt ctcgtgtggc ttcaggcctg ggcggcgagc
     1021 acccgggtct ccttaccaga gcctgattcc atagcgtgcg cctcgccccc tgaactccag
     1081 ggcgtgccag tgcaccgtct gccagccctg ccctgcgcac cgcccagcgt gcgtctgagc
     1141 gcagaaccgc cgcctgaggc tcctggcacc cctctgcgcg caggcttgtc tttcttgtta
     1201 cactgcgtcg ccgaaggcca ccccacaccc cgcctgcaat ggcaacttca gatccctggt
     1261 ggcactgtag tcttagtgcc accggttctc agcaaggaag aagatggagg agaaaaagta
     1321 gatgatgggg agggtgacgg agatgaggac cagcctacgc aaactgaagc gccaaccccc
     1381 actccagcac ctgcttggcc agcgcctcca gccaccccgc gcttcttggc cctcgcaaat
     1441 ggctctctgt tggtgcccct cctgagtgcc aaggaggcag gcatctacac ttgtcgtgca
     1501 cacaatgagc tgggcaccaa ctcaacgtcc ttacgggtga cggtggctgc agcggggccg
     1561 ccaaaacacg ctcctggaac aggggaagaa cctgatgcac aggccccgac ctctgagcgc
     1621 aaggccacca ctaagggccg tagcaacagt gtcctgccct tcaagcctga aggcaaaacc
     1681 aaaggtcaag gtctggcccg agtcagcatc ctcggagaaa cggaggcaga gttggaggag
     1741 acagatgaag aagagcagat gggaggtcag atccctgcag atccgatggg ggagaagcac
     1801 tgtggccatg gggacccctc tcgctatgtg tctaaccatg cattcaacca gagctcagat
     1861 ctcaagccgc acgtttttga gttgggcgta atcgcgctgg acgtagcaga gcgtgaggct
     1921 cgggtgcagc tgacgccact tgctgcgcgc tggggccctg gaccagatgg tgctagcgga
     1981 gcgcggcggc ctgggaggcg gccactgcgc ctactctatc tgtgtcctgc gggaggtggc
     2041 acagcggttc agtggtcacg agtggaggag ggggtcaatg cctactggtt tcgcggcctg
     2101 cggcctggca ccaactactc cgtatgcctg gcactggcgg gcgaggcgtg ccacgtgcaa
     2161 gtggtgtttt ccaccaagaa agagctgcca tccctgctgg ttatcgtaac cgtgagcgtt
     2221 tttctcctgg tgctggccac cgtgcccctg ctgggtgccg cctgctgcca tctactggcc
     2281 aaacacccgg gcaaaccata tcgtttaatc ctgaggccac aggccccgga ccctatggag
     2341 aaacgcatcg ctgccgattt cgacccgcgt gcctcctacc tcgagtctga gaaaagctac
     2401 cccgcccgcg gcgaggcggg aggtgaggag ccagaggagg tcccggaaga aggccttgat
     2461 gaagatgtgg agcagggcga cccaagtggg gaccttcaga gagaggaaag cctggcagct
     2521 tgctcattgg tggagtctca gtccaaagcc aaccaagaag agttcgaggc tggttctgag
     2581 tacagcgatc ggctgcccct gggagcggaa gcagtcaaca tcgcccagga gataaacggc
     2641 aactacaggc agacagcggg ctgagtcccc agcacggctg gcctgcccac ccccaccttg
     2701 ggtaccttgt agcctaggga tggcaggact ttactacccc acaggacccc gccccacccc
     2761 caagccttta gttactctgc ctccttagcc ctccccaggg gtcactacta ggggtttcta
     2821 ggagtgggcc gaattcaaag gtcattctct tggtgggctt gaatccccat ccctacccaa
     2881 agcacagagt caggctccta cctcctctaa gacaccaccc aagggcgtgg agaaaccatc
     2941 ttcactttcc attccaccac gacggactgc gaaacccatc gcgcacccca tccggtggaa
     3001 ctaggaggca aggggaacgt gccacgccag ttgttggcca catctggtga taataatggg
     3061 ttggtcccgc gtttgtccgg gatccccagg acaggtccct agtgtggagc actgtggctc
     3121 tcaccttgat cctactctgc cttttcaagg ttgcatgtgc ccgcaaattt ttactctcaa
     3181 agctcctttc ctataatgat ccaaatctgc gcgtcccccc atccctagtt ggagccaagc
     3241 tgggttcctg gtaggccttc caactcagcg cactgatttt cttattttcg ttgtttttta
     3301 aaaaaaaaaa aaaacagcga aatttctggg tctggtgcta ataccccctt cccaccttct
     3361 gggaaatcgg gtgcgagtgt gtggggtgtg agtttgtcag gtgtgagagt cggaatctgt
     3421 tttcttctgg ctctctccta atgtcaagcg ctccgggatt gcgcacccct tttcctcaaa
     3481 gagcgagtcc ttggttcccg ggccagtttc gttgtcattg tgttgcagac gccagaggtt
     3541 ggtgcgtgcc acagtggctc ttgctactcc atggggtcca gaccccagca ggagcgtgct
     3601 ggggacgcag ggagctgtga ctccccgggc gcatctaacg agcaggcctg cctcaggcct
     3661 gagtgaggcg gcagctgagt gcgaagtcgg ggagggacac cctagttccc cgcgtcgccc
     3721 ctcctcccgg gaaaatagag tttgcccagc gtgtagtccc cgctgagcgt gggctataga
     3781 cttctgtgtc ctgtaaagtg tgacagtata gtgtaggggg gcggagggga gggagcgggc
     3841 gggcaggtgg acgaggaagg agggagggag agggcgggag cggcgagggg actacgtgga
     3901 gtcaggtttt agttctttta ggaaaacgtc tgggggtggg tttcaggcgt ctggaccaag
     3961 gctctggctc tggtcgaagt gcagcacaag cgtgggtggc ccggtgagga gttgaccccg
     4021 gagcccacgt ccttttctaa atgcttctgt atgtaaactg tcaataaaat aatcgatttg
     4081 aa
//
