LOCUS       NM_001135742            6116 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus immunity-related GTPase Q (Irgq), mRNA.
ACCESSION   NM_001135742 XM_218444 XR_009096
VERSION     NM_001135742.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000033.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001135742.4.
            
            On Mar 12, 2021 this sequence version replaced NM_001135742.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            CDS exon combination :: CB725066.1, CB786751.1 [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMD00132261, SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-162               JACYVU010000033.1  4000879-4001040
            163-694             JACYVU010000033.1  4001513-4002044
            695-6116            JACYVU010000033.1  4003414-4008835
FEATURES             Location/Qualifiers
     source          1..6116
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..6116
                     /gene="Irgq"
                     /gene_synonym="RGD1309409"
                     /note="immunity-related GTPase Q"
                     /db_xref="GeneID:292708"
                     /db_xref="RGD:1309409"
     exon            1..162
                     /gene="Irgq"
                     /gene_synonym="RGD1309409"
                     /inference="alignment:Splign:2.1.0"
     exon            163..694
                     /gene="Irgq"
                     /gene_synonym="RGD1309409"
                     /inference="alignment:Splign:2.1.0"
     CDS             165..1916
                     /gene="Irgq"
                     /gene_synonym="RGD1309409"
                     /note="immunity-related GTPase family, Q"
                     /codon_start=1
                     /product="immunity-related GTPase family Q protein"
                     /protein_id="NP_001129214.3"
                     /db_xref="GeneID:292708"
                     /db_xref="RGD:1309409"
                     /translation="MPLPQGDVTALFLGPPGSGKSALIAALCGKNVDAVEIPDGRPDS
                     GVPSLRAAAPGLFLGELSCPPAAPGPWAAEANLLVLVLPGSEGSEEPLTPALGEAARA
                     ALARGTPLLAVRNLRPGDSQNAAQARDETAALLDSAGLGAAPLFVLPADCSSSDGCEE
                     LERLQVVLRTQAEALQRLLPPAQDGFEVLGAAELEAVREAFETGGLEAALSWVRAGLE
                     RLGSARVDLAVAGTTNVGLVLDMLLGLEPGDAGAAPASAPTEPTPYPAPERPNVVLWT
                     VPLGPTATSPAVTPHPTHYDALILVTPGAPTEENWAQVRSLVSPDAPLVGVRTDGQGE
                     DPPEVLEEEKAGNARDGNSGDARSEGKKPGIGDSGCSAVRSPEDEQWEVLEEAPPPVF
                     PLRPGGLPGLGTWLQRALPTAQAGALLLALPPASPRAARRKAAALRAGAWRPALLASL
                     AAAAAPVPGLGWACDVALLRGQLAEWRRALGIEPAAVARRERALGLAPGVLATRTRFP
                     GPVTRAEVEARLGSWAGEGTAGGAALGALSFLWPAGGAAATGGLGYRAAHGVLLQALD
                     EMLADAEAVLGPPEHNQ"
     exon            695..6116
                     /gene="Irgq"
                     /gene_synonym="RGD1309409"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctccaagaca cacccggtcg tggaaggaat gacgtcagga tagagccacc tgaaggagtc
       61 cggatgtctc taaatccgga caccccttcc ccttcagccg ctgtcatttc gtcttaaggg
      121 gccgggcctc cgtgttctcc aggcgtgtca cctctctgct cgcaatgcct ctgcctcagg
      181 gtgatgtgac tgccttattc ttggggcctc ccggctcggg aaagtccgcg ctgatcgccg
      241 cgttatgcgg taagaatgtg gacgcggtag aaattcccga tggacggccg gactctgggg
      301 tccccagcct aagagctgca gctccgggcc tcttcctggg tgagctgagt tgcccacccg
      361 cagcccccgg gccctgggcg gcggaggcca acttgctggt attggtgcta ccaggatctg
      421 agggaagcga ggaacccttg accccagctc tgggagaggc agcacgggcc gccctggcca
      481 gaggaacccc gctgctggct gtacggaatc tgcgtcctgg agattcccag aatgcagctc
      541 aggcccggga tgagactgcg gccttgctgg acagtgctgg gttaggagct gcgcctctct
      601 ttgtgctgcc cgcggattgc agcagcagtg acggctgcga ggagctagag cgcctgcagg
      661 tggtgctgcg gacccaggcg gaggcactgc agaggctcct gcctcctgcc caggatggct
      721 tcgaggtgct gggcgcagca gagctggaag ctgttcgtga ggccttcgag actggtggcc
      781 tggaggcggc gctgtcgtgg gtgcgcgctg gtctggagcg cctaggcagc gctcgagtgg
      841 acttggcggt ggccggcacc accaacgtag gccttgtgct ggacatgcta ctggggttgg
      901 agcctggcga cgcgggtgct gcgcctgcct ctgcacccac tgagcccacc ccttatcctg
      961 ctccagagcg ccccaatgta gtgctctgga ccgttcccct gggccccaca gccacatccc
     1021 ctgccgtcac ccctcacccg acccactacg atgccctgat cctcgtcacc cctggggctc
     1081 ctacggagga gaactgggcc caggtccgct cgttggtgtc cccagatgct ccactcgtcg
     1141 gtgtgcgcac tgacggccag ggcgaagatc cacccgaggt tctggaagaa gaaaaggctg
     1201 ggaatgcaag ggatgggaac tcaggcgatg cacgcagcga aggaaagaaa cctggcatcg
     1261 gggactcagg atgctctgcg gttcggagcc cagaggatga gcagtgggag gtgctggagg
     1321 aggcgcctcc gcccgtgttc cctctgaggc ccggcggcct cccgggcctg ggaacttggc
     1381 tgcagcgggc actgcccaca gctcaggcgg gagcgctgct gctggcgctg ccacccgcaa
     1441 gtcctcgggc ggcgcggagg aaggcggcag cattgcgggc aggggcgtgg aggccagccc
     1501 tcctggctag cctggcggca gccgccgctc cagtaccagg actgggctgg gcttgcgatg
     1561 tggcgcttct ccggggacag ctggccgagt ggaggcgcgc gctgggcatc gaacctgcgg
     1621 ccgtggcacg acgtgagcgc gccttgggcc tggctcccgg agtactggcc acgcgcacgc
     1681 gcttcccggg gccggtgacg cgagccgagg tagaggccag gctggggtcc tgggcaggtg
     1741 agggcacggc cggaggtgcg gcattgggcg cgctctcctt cctatggccg gccggtggtg
     1801 cagcggcaac aggtgggctg ggttaccgtg ctgcgcatgg tgtactgctg caagccttgg
     1861 atgagatgct ggctgatgct gaggcggtgc tgggaccccc agagcacaat cagtaaggcg
     1921 cgcggtgggg cttggggcaa ctggtgactt ggttcgtagc cccatagcct ctgagattaa
     1981 ggagtgaagt tgtgttactc aaatccggag acttgaagga gactggcatc tcgttgaaat
     2041 ccgagaccta cagtcacccg atttccgtgg ctctgaatgg gagtaaggtc tatgcgccag
     2101 aagtgtgtca gccagatacc aatgcagtaa agggaattga gggcctggga ctcatagaaa
     2161 tgggagcctt ttggcgtcca gctgacacct ggtcctcaat ctctagaagc cttgattcct
     2221 gccttcctat gagtgaacct atgactatgg accgggtgct tcagggagtt agaatccttg
     2281 gagcgctggg tcccaaaggg aaacgagacg taagttgtcc gatgaaagaa cagatttgcc
     2341 ggagctgtga gagtcttaga aaaagtctgg ttcctaagaa ggctctagag attggttgtc
     2401 atttcttggg tggtgggaag cctgtgggag accaggggcc tgctggagac cctttgatct
     2461 ggagtgtgga agattgtcat ttgctcttca aggctttggt gtagagaata ctgtcccaca
     2521 aaattgaaga gaagggacag ggagggtctg ggtaaggtag tcttccgatg gtcagagcct
     2581 aagaatgggg cctatagggt atggaaaaat agcaacccac acttggaaat acctcccttg
     2641 agcctctgat gaactgggat cgtggcttta ctggaaaagg gtgtgactac ccccatttta
     2701 taggtgctgg gtgattcagg gtctccggca tgtgtgctcc tgtttattac tggttttttc
     2761 tgccatatgg accttaaccg ttggacctcc tgctcatccg gaaaggcaag agtcctactg
     2821 tggcagccta tggttttctg catgacgacc tctgatcgat ttctccaaga tacgtgctgc
     2881 tggtccacac aggatgctgc tgagagtggg ggtcccccac aggatagctg ggtaggccat
     2941 tgacgctgga ggaaagtgcc aggagggagg cagaggcaga aaccacagtg cgcatgcgca
     3001 tcagctttgc acagatgcga gaagccatgt atgattcccc agtgttgaaa acaggagggc
     3061 gtggcagatg ggcccacccg gttcagagag gcagtgtgtg gcctgaccct gcctattctc
     3121 ggttcccagc ccatctccag caagcctgat ttgttgttct gatgctcagg tcccgcctcg
     3181 ggacttaggc atggttttct atggaacact ctgcctctcc gtcttttatg aggtagggtc
     3241 ctcattgtca ggtctccccg aaatggctct atgatcaccc aaagtagctt gcattgatcc
     3301 tggccacttg atcgtccctg tagcgaacat tgctatcaat ggctttattt attcactcat
     3361 tcatttattt gcctgttcat tggctcttgc tccttgcctg tctttctctt gggtgtaccc
     3421 tagtacccag agcagtgcct gacacacggt aggtgcctag tatttattat cctggtttat
     3481 tgatcattgg cacatggcct ggaattcagg ttgtcagtaa ccttgttaca aaaaagggac
     3541 aagctaggga gaagcgagcc cctggtggga gagcaaaccg aagcaggaga gcttggcccc
     3601 tgtcacctca tgagcaagtg ccgtatattt tcacctggta gatgaaagga ctggactaga
     3661 accataagag tttctgaggg ctagtgattg gaggttgcat agctgggctt taccccatct
     3721 aaccttgaat tctcacctct gacaccattc accctatgaa agggggcatc ggatttggct
     3781 gttcatgcct gtaatccccg cgcctcaggt tgacacagga gaatttgaaa tgtaaggctg
     3841 tcttcggtga catagagaat tgcaggccca taagcttcat gcctgatccc atcagagtct
     3901 agatggacct tgaactccac atggtctggc cctgaatctt ctcattccct gttcagccca
     3961 tctccagcca gcctgatact aagtccttct ccatgcttga ccagctttgg ccctgcctcg
     4021 gcctccccag tgccagggtt atggctctaa accacagcac ctggcttcga tgttaaagct
     4081 cttaggtcag cctgacactt atcaccgagt caccagaaca gatgcgttcc ttacacctga
     4141 gcacacctca ggtcacgtga tagatctaat tggaaatact tgatagattg aggacccaat
     4201 tcacataccc gtgttttaat tatatttgac aggtcccccc cccccccaat agttcaatca
     4261 atgcctcaca tattagaggc aaacagtctg atggaaccgt atccccagct ctgggggctg
     4321 ggggtggagt tctgggcagg gcctccacca ctaagccacg cccacaggcc ctcattgggg
     4381 gagtctaggc aggggctgta cctctgagct atgtccatat ttctagacaa ggtctcacta
     4441 agttgcctgg gctgcccttg aactcactgt attccagaca ggccttgaat ttgggatcct
     4501 actctcagcc tcccaagtaa gtgggatcac aggcctgtct cacctcctgg ctcagttttc
     4561 tcaaacctgc gatgttctgg tggatcgaat acaaatagga tctgagattg attcttttcc
     4621 tcagtggcat ttgccacaca tttggatcac agttcaatag cacagcccat tgtgggagaa
     4681 ctatagcggc aagagaggag acgggtatcc acattgcaca gccgcatttg ggaagtagag
     4741 aaatcactct ctcctttgtc ttcatcccag gaccacagct ctgaggacta gtgcctctaa
     4801 cagtaggtga ccccgcctca tttatcccag tctagacact cctccacagc cctggccaga
     4861 gttaatgtga attctgtcag ttaacactga ccatcacaga cagcaggtag ctgaggattt
     4921 gctgttacac acgcatgtgg ctaagcatat gcatactggc acgtaagtgt gctcaaacac
     4981 atacccagct cacaggtact gcagcccctc ctcagaagct tggaactcaa tgttattcct
     5041 ctactgcctt ggccctattt ctttggtctg gctacagtaa cagccacctt gctctcctgt
     5101 gacttcctgt taagtgtcct gcattctcta aaccctctgg tcctttgact tcttttttgg
     5161 tattttgaca tagcctaggc ttgccttcaa ctctgtatgt agccagtgat ggccttgaag
     5221 tcccaatcct ccctccacct ctcaagtgct gggatcacag gcatgcggcc ctatgctcgg
     5281 ctctgaccat gtcctgcttt ggtgccgcat ggcgtccctg tcctgtgctt tgctgccgtc
     5341 tcttctcctt gaggccggag gcccatggta gaggcatcgg gaaaaagcac aatgtggtca
     5401 ttgtgcacgt tctggtcagc tccataaact tgtatacggg cacttttgtg tgttgggatt
     5461 ccttgcccat ttttgttttg ttgcttggag agagaatcta ggccatctca aacacctgag
     5521 gccaggtgct cctcctgtcc cagcctctcc ttgtcctgga ttataggtag aggtggctgc
     5581 cttttaaact ataattcccc ctcccccgag atagggcctt acttactcta taactctaac
     5641 tcatggcttg gcatctgaag agctggggtt accggtgcaa atgactacat gttgcctatg
     5701 tgatcttttg ttagggtttc tcagcttttc cagaatgtaa gtaaagctaa gagtgagacc
     5761 tccggaagcc tccaaataga aaaggttcag tctcccttgt cacaggtcac tggctgccag
     5821 ccgagctccc atgaggcact tcaggtctgg aagagcctgg acacaggaat tctgggaaat
     5881 gtcagtcttc catgctggaa ttgcaactat acaatcttgg cattgccctt gaaagacaag
     5941 caggtttcag aagtcggtga atgaatgagg tgccctcctc aacatggaca gagtctcaca
     6001 cttctggctc atgaaggaac tgtctattag aatgtgtgtg tgtggggggg ggggggaatc
     6061 tgtctggtca acctgtggtg tgttttggaa aaaagaataa aagggtagaa atacta
//
