LOCUS       NM_001047086            1368 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus interferon regulatory factor 2 (Irf2), mRNA.
ACCESSION   NM_001047086 XM_001060435 XM_214350
VERSION     NM_001047086.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1368)
  AUTHORS   Sun,L., Jiang,Z., Acosta-Rodriguez,V.A., Berger,M., Du,X.,
            Choi,J.H., Wang,J., Wang,K.W., Kilaru,G.K., Mohawk,J.A., Quan,J.,
            Scott,L., Hildebrand,S., Li,X., Tang,M., Zhan,X., Murray,A.R., La
            Vine,D., Moresco,E.M.Y., Takahashi,J.S. and Beutler,B.
  TITLE     HCFC2 is needed for IRF1- and IRF2-dependent Tlr3 transcription and
            for survival during viral infections
  JOURNAL   J Exp Med 214 (11), 3263-3277 (2017)
   PUBMED   28970238
REFERENCE   2  (bases 1 to 1368)
  AUTHORS   Schoggins,J.W., Wilson,S.J., Panis,M., Murphy,M.Y., Jones,C.T.,
            Bieniasz,P. and Rice,C.M.
  TITLE     A diverse range of gene products are effectors of the type I
            interferon antiviral response
  JOURNAL   Nature 472 (7344), 481-485 (2011)
   PUBMED   21478870
  REMARK    Erratum:[Nature. 2015 Sep 3;525(7567):144. PMID: 26153858]
REFERENCE   3  (bases 1 to 1368)
  AUTHORS   Aziz,F., van Wijnen,A.J., Vaughan,P.S., Wu,S., Shakoori,A.R.,
            Lian,J.B., Soprano,K.J., Stein,J.L. and Stein,G.S.
  TITLE     The integrated activities of IRF-2 (HiNF-M), CDP/cut (HiNF-D) and
            H4TF-2 (HiNF-P) regulate transcription of a cell cycle controlled
            human histone H4 gene: mechanistic differences between distinct H4
            genes
  JOURNAL   Mol Biol Rep 25 (1), 1-12 (1998)
   PUBMED   9540062
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from DQ674266.1.
            
            On or before Sep 7, 2006 this sequence version replaced
            XM_214350.4, XM_001060435.1.
            
            Sequence Note: This sequence has been modified as follows: removed
            25 bp suspected to be vector contamination from the 3' end.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DQ674266.1, BC166593.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760400, SAMN12840111
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1368              DQ674266.1         1-1368
FEATURES             Location/Qualifiers
     source          1..1368
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16q11"
     gene            1..1368
                     /gene="Irf2"
                     /note="interferon regulatory factor 2"
                     /db_xref="GeneID:290749"
                     /db_xref="RGD:1304922"
     exon            1..109
                     /gene="Irf2"
                     /inference="alignment:Splign:2.1.0"
     exon            110..202
                     /gene="Irf2"
                     /inference="alignment:Splign:2.1.0"
     CDS             116..1165
                     /gene="Irf2"
                     /codon_start=1
                     /product="interferon regulatory factor 2"
                     /protein_id="NP_001040551.1"
                     /db_xref="GeneID:290749"
                     /db_xref="RGD:1304922"
                     /translation="MPVERMRMRPWLEEQINSNTIPGLKWLNKEKKIFQIPWMHAARH
                     GWDVEKDAPLFRNWAIHTGKHQPGVDKPDPKTWKANFRCAMNSLPDIEEVKDRSIKKG
                     NNAFRVYRMLPLSERPSKKGKKPKTEKEERVKHIKQEPVESSLGLSNGVSGFSPEYAV
                     LTSAIKNEVDSTVNIIVVGQSHLDSNIEDQEIVTNPPDICQVVEVTTESDDQPVSMSE
                     LYPLQISPVSSYAESETTDSVPSDEENAEGRPHWRKRNIEGKQYLSNMGTRNNCLLPS
                     MATFVTSSKPDLQVTIKEESCPMPYNSSWPPFTDISLPAPVTPTPSSSRPDREARASV
                     IKKTSDITQARVKSC"
     exon            203..302
                     /gene="Irf2"
                     /inference="alignment:Splign:2.1.0"
     exon            303..479
                     /gene="Irf2"
                     /inference="alignment:Splign:2.1.0"
     exon            480..526
                     /gene="Irf2"
                     /inference="alignment:Splign:2.1.0"
     exon            527..644
                     /gene="Irf2"
                     /inference="alignment:Splign:2.1.0"
     exon            645..809
                     /gene="Irf2"
                     /inference="alignment:Splign:2.1.0"
     exon            810..856
                     /gene="Irf2"
                     /inference="alignment:Splign:2.1.0"
     exon            857..1368
                     /gene="Irf2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctgcgatta ttcaactgac gggctttcat ttccatttta cacaccctaa caacacttac
       61 accttgcggg attgtattgg tagcgtgaaa aaaaaaagca cactgagagg gtaccatgcc
      121 ggtggaacgg atgcgaatgc gcccgtggct ggaggagcag ataaattcaa atacgatacc
      181 agggctaaag tggctgaaca aggaaaagaa gattttccag atcccctgga tgcatgcagc
      241 tagacacggt tgggacgtag aaaaggatgc tccactcttt agaaactggg caatccatac
      301 aggaaagcat caaccaggag tagataaacc agatccgaaa acatggaaag caaattttcg
      361 atgtgccatg aattccttgc ccgacattga ggaagtgaag gacagaagca taaagaaagg
      421 aaacaacgcc ttcagagtct accggatgtt acccttatct gagcgacctt ccaagaaagg
      481 aaagaaacca aagacagaga aagaagagag agttaagcac atcaagcaag aaccagttga
      541 gtcatctttg gggcttagta atggagtaag tggcttttct cctgagtatg cggtcctgac
      601 ttcagctata aaaaatgaag tggatagtac ggtgaacatc atagttgtag gacagtccca
      661 tctggacagc aacattgaag atcaagagat cgtcactaac ccgccagaca tctgccaggt
      721 tgtagaagtg accaccgaga gtgatgacca gccagtcagc atgagcgagc tctaccctct
      781 acagatttct cctgtgtctt cctatgcaga aagcgaaact accgacagtg tgcccagcga
      841 tgaggagaac gcagagggga gaccacactg gcggaagagg aacatcgaag gcaagcagta
      901 cctcagcaac atggggacac gtaacaactg tctgctgcct agcatggcga cttttgtcac
      961 ttccagcaaa ccagatctgc aggtcaccat caaagaggag agctgtccaa tgccttacaa
     1021 cagctcctgg ccgccgttta cagacatctc ccttcctgcc ccagtgaccc ccacgcccag
     1081 cagcagtcgg ccggaccggg aggcccgggc cagtgtcatc aagaagacat ctgatatcac
     1141 ccaggcccgt gtcaagagct gctaagcctt tggctctccc tggtggttgt tggaatttct
     1201 tagctttgtg ttgttatttg tttgtatttt attttttctc tatgatacct atcttagaca
     1261 aatctaaggg aaaaagcctt gacaatagaa tattgattgc tgtgtccgac tccagagctg
     1321 gagtttcttc ttaactcagg actccagccc cccctcggta gatgcata
//
