LOCUS       XM_039103456            6077 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus IQ motif containing GTPase activating
            protein 2 (Iqgap2), transcript variant X1, mRNA.
ACCESSION   XM_039103456
VERSION     XM_039103456.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051337.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Jan 10, 2024 this sequence was replaced by
            NM_001427125.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6077
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6077
                     /gene="Iqgap2"
                     /note="IQ motif containing GTPase activating protein 2;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 56 ESTs, 5 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 67 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:100360623"
                     /db_xref="RGD:2321734"
     CDS             525..5252
                     /gene="Iqgap2"
                     /codon_start=1
                     /product="ras GTPase-activating-like protein IQGAP2
                     isoform X1"
                     /protein_id="XP_038959384.1"
                     /db_xref="GeneID:100360623"
                     /db_xref="RGD:2321734"
                     /translation="MPHEELPSLQRPRYGSIVDDERLSAEEMDERRRQNIAYEYLCHL
                     EEAKRWMEVCLVEELPPTTELEEGLRNGVYLAKLAKFFAPKVVSEKKIYDVEQSRYKK
                     SGLHFRHTDNTVQWLRAMEAIGLPKIFYPETTDVYDRKNIPRMIYCIHALSLYLFKLG
                     IAPQIQDLLGKVDFTEEEISNMRKELEKYGIQMPAFSKIGGILASELSVDEAALHAAV
                     IAINEAIEKGVAKQTIITLRNPNAVLTCVDDSLSQEYQKELWEAKKKKEETAKLKNSC
                     ISEEERDAYEELLTQAEIQSNIHAVNRMAAVDHINAVLREGDPENTLLALKKPEAQLP
                     AVYPFAAAMYQNELFNLQKQNTSNYLAHEELLIAVEMLSAVALLNQALESNDLVAVQN
                     QLRSPTIGFNNLDEAHVDRYADALLSVKQEALSQGQDTLSWNEIQNCIDMINNQIQEE
                     NERMVVLGYINEAIDEGNPLKTLDTLLLPTANIRGVDPDCAHHYQDVLFHTKSQKLRD
                     PKNVSKVLWLDEIQQAINEANVDKNRAKQWVTLVVGVNECLDRKQSDDILTVLKSSSS
                     NVHNILPECANKYFDTLMKAKESKTDGEPTEGPWVKLDVQQKYNYYYNTDSKEGSWIP
                     PESCLCKESWLTGEEIEDIVEKVTSDYIRENLWSASEDLLLRFEATNSGPILREEFEA
                     RKAFLYKQVGNVVKIQAFWKGYKQRQEYLHRQQVFARNVDSVVKIQSWFRMVTARKSY
                     LSRLQYFEDHENEIVKIQSLLRASKARDDYKALVGSENPPLTVIRKFVYLLDQSDLDF
                     QEELEVARLREEVVTKIRANQQLEKDLNLMDIKIGLLVKNRITLEDVISHSKKLNKKK
                     GGEIEILTNTDNQGIKSLSKERRKTLETYQQLFYLLQTKPSYLAKLIFQMPQNKSTKF
                     MDTVIFTLYNYASNQREEYLLLKLFKTALEEEIKSKVDQVQDIVTGNPTVIKMVVSFN
                     RGARGQNSLRQLLAPVVKEIIEDKALIINTNPVEVYKAWVNQLETQTGEASKLPYDVT
                     TEQALTYPEVKNKLEASIENLRKVTDKVLSSIISSLDLLPYGLRYIAKVLKNSIREKF
                     PDATEEELLKIVGNLLYYRYMNPAIVAPDGFDIIDMTAGGQINSNQRRNLGSVAKVLQ
                     HAASNKLFEGENEHLSSMNNYLSETYQEFRKYFQEACDVHEPEEKFNMDKYTDLVTVS
                     KPVIYISIEEIINTHLLLLEHQDAIATEESDLLNELLESLGEVPTVESFLGEGAVDPN
                     DPNKENTLNQLSKTEISLSLTSKYDVKDGEAIDGRSLMIKTKKLIIDVVRNQPGSTLM
                     EILETPATEQQELEHTKDMESRAVADSRALEEGKQSQAVIEDASLPLEQKKRKIQRNL
                     RTLEQTGHVSSKNKYQDILNEIAKDIRNQRIHRKLRKAELSKLQQTLNALNKKAAFYE
                     DQINYYDTYIKTCVDNLKRKNSRRSIKLDGKAEPKGTKRVKPVRYTAAKLHDKGVLLG
                     IDDLQTNQFKNVMFDIIATEDMGIFDVRSKFLGVEMEKVQLNIQDLLQMQYEGVAVMK
                     MFDKVKVNVNLLIYLLNKKFYGK"
ORIGIN      
        1 agggtgtctg tggtctgctt tggtttttct tgctcttccg tgagctggtt cacttccacc
       61 ctccggatgc tccaaggcgc tctcctgcgc acggggctcc agttgcaggg gtccagtgcc
      121 tctcatcccc ttcctcccgc gggaggcggg tccttgcaag caggcgctgc gcggtgcgac
      181 cagtaggggt cgctgctcgg cggcgcgctc ccaccgcggt gaataacggg gccgggcggg
      241 aggagaaagg aaacctgctg ggggaggcgg tgcggcccgc gggcgggcgg gcgagcgagc
      301 gagggaggag agagttcact tttgccccgg tgtcagcgag acgcggccgc cgcaggcgcg
      361 ggcgaaagag caccgaggga gcgggtcggc cagctcggag aagccggccg agggcagcca
      421 gaggtgggat cggagcgcgc ccgccgggcg cggagcccgc gagcctggcc agcgagggaa
      481 accacggggg tcgcgccccg ggagggcccc cggagcagcg caggatgccg cacgaagagc
      541 tgccgtcgct gcaacggccc cgctacggct caattgtgga tgatgaaagg ctgtctgcag
      601 aggagatgga tgagaggagg cgacagaaca tcgcctatga atacttgtgt cacctggagg
      661 aagccaagag atggatggaa gtctgcttgg ttgaagaatt gccaccaacc actgagctgg
      721 aagaagggct ccggaatggg gtctacctcg cgaagttagc caaattcttt gctccgaagg
      781 tggtgtcaga gaagaagatc tatgatgtgg agcagtcgcg ctataagaaa tctggccttc
      841 atttccgaca cacagataac accgtgcagt ggttaagagc tatggaggcc attgggctgc
      901 ccaagatatt ttatccagaa acgacagatg tctacgaccg gaaaaacata ccaaggatga
      961 tctattgcat tcacgcgcta agtttgtatc tgtttaaact ggggattgca ccccagatcc
     1021 aggatttgct gggaaaagtg gatttcacag aggaggaaat cagtaatatg aggaaagaac
     1081 tggagaagta cgggatacag atgccagctt tcagcaaaat cggcggcatt ctggccagcg
     1141 agctgtccgt ggacgaagct gcactgcatg ctgcagtcat agccattaat gaggctatcg
     1201 agaagggagt ggccaagcag accattataa cactaagaaa ccccaatgcg gtgttaactt
     1261 gtgtggatga cagcctctcc caggaatacc agaaagaact gtgggaagcc aaaaagaaaa
     1321 aagaggaaac cgcaaaactg aagaacagct gtatttcaga ggaagagaga gacgcatatg
     1381 aggagctgct gacacaggca gaaattcaga gcaacatcca tgcggtcaac aggatggctg
     1441 ccgtggacca catcaatgct gtccttcggg aaggtgaccc tgagaacaca ctgcttgcac
     1501 tgaagaaacc ggaagcccag ctgccagctg tctatccctt tgctgctgct atgtatcaaa
     1561 atgaactctt caacctccag aaacagaaca catcgaacta cttggcccac gaggagctcc
     1621 tgattgccgt ggaaatgttg tccgctgttg ctctactaaa ccaggccttg gagagcaatg
     1681 acctcgtggc tgtacagaac caactcagaa gccccaccat aggcttcaac aatctggatg
     1741 aggcacacgt ggaccgttat gcagacgcac tactctctgt taaacaggaa gcattatccc
     1801 aggggcaaga taccttaagc tggaatgaaa ttcagaattg tattgatatg attaataacc
     1861 agattcaaga agaaaatgag cgaatggtag ttctcggtta catcaatgaa gccatcgacg
     1921 aagggaaccc tctgaagact ttagatacct tgctgctgcc cactgctaac atcagaggtg
     1981 tggacccaga ctgtgcccat cactaccagg atgttctgtt ccacacaaaa tcccagaaac
     2041 tcagggatcc taagaatgtt tctaaagttc tctggctgga tgaaatacag caagccatca
     2101 atgaggccaa cgtggacaag aacagagcaa agcaatgggt tacactggtt gttggtgtca
     2161 acgagtgttt ggatagaaaa caatcagatg atatcttgac tgtactcaag tcttcttcta
     2221 gtaatgttca taacatactc ccagaatgtg ccaacaagta ctttgatacc cttatgaagg
     2281 cgaaagagtc gaagactgac ggcgagccca ctgaaggtcc atgggtcaag ctcgacgtgc
     2341 agcagaaata taactactat tacaacacag attccaaaga aggctcttgg atcccacctg
     2401 aatcgtgctt gtgtaaggaa tcatggctca caggagaaga aattgaggac atcgtggaga
     2461 aggtcacctc agattacatc cgtgagaacc tgtggtctgc ttcagaagac ttgcttctcc
     2521 gctttgaagc cacaaactca ggacccatcc tgagggagga gtttgaagct cggaaagcat
     2581 tcttatataa acaagtagga aacgtggtca aaatacaggc tttctggaag ggatacaaac
     2641 agcgccagga atatctacac agacaacaag tgtttgctcg caacgttgac tctgttgtga
     2701 agattcagtc ctggttccga atggtgacag caaggaagag ctacctttcg cgactgcagt
     2761 attttgaaga ccacgaaaat gaaatcgtga aaatacaatc cctgttgcgg gccagcaaag
     2821 ccagagacga ctacaaagca ctggttggct ctgaaaaccc accgttgact gtaatccgga
     2881 agtttgtgta cctgttggac cagagcgact tggatttcca ggaggagctg gaggtagcga
     2941 ggttgcgaga agaagtagtg actaagatca gggccaatca gcagctggag aaggacctga
     3001 acctgatgga catcaagatt ggactgctgg tgaagaacag gatcacgctg gaggatgtaa
     3061 tctcacacag taaaaagctg aataagaaaa aagggggcga aatagaaata ctgactaaca
     3121 ctgacaacca ggggattaaa agcctgagca aagagagacg aaaaacactg gagacttacc
     3181 agcaactctt ctaccttctc cagaccaaac cttcatacct ggctaagctg attttccaga
     3241 tgccacagaa caagtcgacg aagttcatgg acactgttat cttcacactg tacaattacg
     3301 cctctaatca gagagaagag tacctgctgc tcaagctttt caaaaccgcc ctggaggagg
     3361 aaatcaagtc aaaggtggac caggtacaag acatagtgac aggcaaccct acagtcatca
     3421 agatggttgt cagcttcaac agaggtgccc ggggacagaa cagcctgcgc cagctcctgg
     3481 caccagtggt gaaagagatc attgaggaca aggccctgat catcaatacc aaccctgtgg
     3541 aggtgtacaa ggcctgggtg aaccaactgg aaacgcagac tggagaggcc agcaagctgc
     3601 cttacgatgt gaccacagag caagccctga catacccgga ggtgaaaaat aaactggagg
     3661 catctattga aaacctgagg aaggtcactg acaaagtcct gagctccatc atttcttccc
     3721 tcgatctgct gccttatgga ttgaggtata tagccaaagt cctgaagaac tcgatccgtg
     3781 agaaatttcc cgatgccaca gaagaagagc tgttaaagat tgttggaaac ctcctatact
     3841 accgatacat gaacccagcc attgtggctc ccgatggctt tgacatcatt gacatgacag
     3901 ccggaggtca gataaactcc aaccaaagga ggaacttggg atccgtggca aaggttctgc
     3961 aacacgcagc ctccaacaag ctgtttgaag gagagaatga gcatctatca tcaatgaaca
     4021 attatttatc agagacctat caggaattca ggaaatattt tcaagaagca tgtgatgtgc
     4081 atgaaccgga agagaagttt aatatggaca aatacacgga cttggtgacc gtcagcaaac
     4141 cagttattta tatctccata gaagaaatca tcaatacaca tttactccta ctggaacatc
     4201 aggacgccat tgccactgaa gagagtgacc tgctgaacga actgctggag tcgctggggg
     4261 aggtgcccac agtggagtcc tttcttgggg aaggagccgt tgaccccaat gaccctaaca
     4321 aggaaaacac actaaatcag ctctcaaaga ctgagatctc cctttccttg acaagcaagt
     4381 atgatgtcaa ggatggtgag gctatcgatg gcaggagcct catgataaag accaaaaagc
     4441 tgatcattga tgtggtccgg aaccagccag ggagcacact gatggaaatc ttagagacgc
     4501 cagcaactga gcagcaggaa ctagagcaca ccaaagacat ggagagccgt gctgttgcag
     4561 actccagggc cctggaggaa gggaagcaga gccaagcagt gattgaagat gcgagcctgc
     4621 ctcttgagca aaagaagagg aagatccaga ggaatctacg gacgctggag cagactggac
     4681 acgtgtcctc caaaaacaag taccaagaca ttctcaacga gatcgccaag gatattcgaa
     4741 atcaaagaat ccaccgcaag cttcgaaagg ctgagctgtc aaaacttcag cagaccctga
     4801 acgcacttaa taagaaggca gcattttatg aggatcaaat taattattat gacacctaca
     4861 tcaagacctg tgtagacaac ctgaaaagaa aaaattctcg gagatcaatt aaactggatg
     4921 gaaaagcaga acccaaagga acgaagagag tgaagccagt gaggtacaca gcagcaaaac
     4981 tacatgacaa aggtgtcctg ctgggcatag atgatcttca aaccaaccag tttaagaatg
     5041 ttatgttcga tatcatagct actgaggaca tgggcatctt tgacgtcaga tccaaattcc
     5101 tcggcgttga gatggaaaag gtgcaactca atattcagga cttacttcag atgcagtatg
     5161 aaggggtggc cgtgatgaag atgttcgata aggtgaaagt aaacgtgaat cttctcattt
     5221 accttctgaa caagaagttc tacgggaagt gacgtgccga ctgctgaggg actcgtggac
     5281 tctctactgc ctgccttgag aaatgagttt gtctagtatt tttgttttaa aacatgattg
     5341 aaatcacggc ttataaatgt gtgatttttt tttttaaaga ccaaaactgt tctgaagaat
     5401 gtagccacgt gcctttttga taattggata ctgcagcagg gggatagaca agatgggctg
     5461 atgggacaca cccagtactg tggcacaggt actccgtctg aaaagttctg aacgccctgt
     5521 gatttgtttt aaagtagggg gagaaagttg agctgactag ggacaaatgt ataaacctat
     5581 tttcctatga aaaaaaattt ttaaatgtcc cacttaaatg atgtaattct tcacagattg
     5641 tttttttttt atctgtggag aaatagagat ctaattaatt tgtaatgaat tatttagaca
     5701 tatagttcta agccctgcct tctgggaatt accggtttta aagagaactt ttgtgcaatt
     5761 caaaatgaag ttttttataa gcaattgaaa gtgatgacac agcaacactt tctgtataaa
     5821 agtatatatt ttatgtgatt tattcgattt attcaaagtg cactactgcc tcatgggaag
     5881 gctcctgtag gaggagtccc aggaaacaca gtggatagca agtagagacc cccaccttca
     5941 ccttcacctt ttatttgaat acttcaattg tgcctctcaa tttttttgta atgctataaa
     6001 atcagtatct agatggtttt taaatgtatt ctttgaaaat tgttttatgt aaaataaatg
     6061 ttacttaatt acatgaa
//
