LOCUS       NM_001415951            5970 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Rattus norvegicus interaction protein for cytohesin exchange
            factors 1 (Ipcef1), mRNA.
ACCESSION   NM_001415951
VERSION     NM_001415951.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5970)
  AUTHORS   Guan,X., Zhu,X. and Tao,Y.X.
  TITLE     Peripheral nerve injury up-regulates expression of interactor
            protein for cytohesin exchange factor 1 (IPCEF1) mRNA in rat dorsal
            root ganglion
  JOURNAL   Naunyn Schmiedebergs Arch Pharmacol 380 (5), 459-463 (2009)
   PUBMED   19756519
  REMARK    GeneRIF: correlation of IPCEF1 mRNA expression with nerve injury
            input in injured dorsal root ganglion suggests that IPCEF1 might
            participate in the mechanisms that underlie nerve injury-induced
            membrane receptor trafficking
REFERENCE   2  (bases 1 to 5970)
  AUTHORS   Venkateswarlu,K.
  TITLE     Interaction protein for cytohesin exchange factors 1 (IPCEF1) binds
            cytohesin 2 and modifies its activity
  JOURNAL   J Biol Chem 278 (44), 43460-43469 (2003)
   PUBMED   12920129
  REMARK    GeneRIF: IPCEF1 increases the in vitro and in vivo stimulation of
            ARFGTP formation by cytohesin 2
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760389
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: lack of evidence for use of
                                                upstream AUG
            inferred exon combination        :: based on alignments, homology
            RefSeq Select criteria           :: based on conservation,
                                                expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-112               JAXUCZ010000001.1  45856882-45856993   c
            113-159             JAXUCZ010000001.1  45767331-45767377   c
            160-199             JAXUCZ010000001.1  45751989-45752028   c
            200-369             JAXUCZ010000001.1  45751180-45751349   c
            370-443             JAXUCZ010000001.1  45728892-45728965   c
            444-515             JAXUCZ010000001.1  45727452-45727523   c
            516-574             JAXUCZ010000001.1  45721268-45721326   c
            575-663             JAXUCZ010000001.1  45719247-45719335   c
            664-1036            JAXUCZ010000001.1  45706246-45706618   c
            1037-1230           JAXUCZ010000001.1  45687652-45687845   c
            1231-5970           JAXUCZ010000001.1  45674248-45678987   c
FEATURES             Location/Qualifiers
     source          1..5970
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q11"
     gene            1..5970
                     /gene="Ipcef1"
                     /note="interaction protein for cytohesin exchange factors
                     1"
                     /db_xref="GeneID:361474"
                     /db_xref="RGD:735159"
     exon            1..112
                     /gene="Ipcef1"
                     /inference="alignment:Splign:2.1.0"
     exon            113..159
                     /gene="Ipcef1"
                     /inference="alignment:Splign:2.1.0"
     exon            160..199
                     /gene="Ipcef1"
                     /inference="alignment:Splign:2.1.0"
     exon            200..369
                     /gene="Ipcef1"
                     /inference="alignment:Splign:2.1.0"
     CDS             211..1431
                     /gene="Ipcef1"
                     /codon_start=1
                     /product="interactor protein for cytohesin exchange
                     factors 1"
                     /protein_id="NP_001402880.1"
                     /db_xref="GeneID:361474"
                     /db_xref="RGD:735159"
                     /translation="MSRRRISCKDLGHADCQGWLYKKKEKGTFLSNKWKKFWVVLKGS
                     SLYWYGNQLAEKADGFVNLPDFTVERASECKKKNAFKINHPQIKTFYFAAENLQEMNM
                     WLNKLGFAVTHKESTTKDEECYSESEQEDPETAVEAPPPPSASATSSPVAARRASSSS
                     PKRRETSCSFSSLENTVKAPSRFSSSGSKERQSWLDIVNSSPATEDVGHPLSFAVQVH
                     TLASSEASSCRVSENSSTTPESGCLNSLSSDDTSSLNNSQDHLTVPDRASGSRMTDRD
                     EIKSSEDDEMEKLYKSLEQASLSPLGDRRPSTKKELRKSFVKRCKNPSINEKLHKIRT
                     LNSTLKCKEHDLAMINQLLDDPKLTARKYREWKVMNTLLIQDIYQQQVPQDPEVTPQE
                     IMNPTSSDCVENSL"
     exon            370..443
                     /gene="Ipcef1"
                     /inference="alignment:Splign:2.1.0"
     exon            444..515
                     /gene="Ipcef1"
                     /inference="alignment:Splign:2.1.0"
     exon            516..574
                     /gene="Ipcef1"
                     /inference="alignment:Splign:2.1.0"
     exon            575..663
                     /gene="Ipcef1"
                     /inference="alignment:Splign:2.1.0"
     exon            664..1036
                     /gene="Ipcef1"
                     /inference="alignment:Splign:2.1.0"
     exon            1037..1230
                     /gene="Ipcef1"
                     /inference="alignment:Splign:2.1.0"
     exon            1231..5970
                     /gene="Ipcef1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agggtttcgg atgcttggag tggaatcttc agccttgacc ttagactagc atgagctttg
       61 tgagttcagg gatccagaga cagctcttgg attggctctc tttccgttgc atattttgtt
      121 tctggcagtc tgacacccag tatggccacc gaaggcaatc aggttccctt gcgtcagaag
      181 cccaggaaga aaactcaagg gtttttcacc atgagtcgga gaaggatatc ctgtaaagat
      241 ctgggccacg ctgactgcca gggctggctg tacaagaaaa aggaaaaggg aactttccta
      301 agcaacaaat ggaaaaagtt ctgggtggtg ctgaaggggt catcactgta ctggtatggc
      361 aatcaattgg cagagaaagc agatggattt gtcaacctgc cagatttcac agtggaaaga
      421 gcctctgaat gcaagaaaaa aaatgcattt aagatcaatc acccacagat caaaaccttc
      481 tactttgcag cagagaattt gcaggaaatg aatatgtggc taaacaaact tggatttgct
      541 gtgacccaca aggaatccac taccaaggat gaagaatgtt acagcgagag cgagcaggaa
      601 gatcctgaaa cagccgtgga ggcaccgccc cctccatccg cgtctgcaac atcctctcct
      661 gtggctgcac ggcgggcatc ttcttcttca cccaaacgga gagaaacatc atgttctttc
      721 tcttctctgg aaaatacagt aaaggcaccc agccggtttt cttcctcggg atctaaagaa
      781 agacagtcgt ggcttgacat agttaacagc tcgcctgcta ccgaagatgt gggacatccc
      841 ctgtcatttg ctgtacaggt ccacacactt gcctcctcag aggcaagcag ttgccgggtc
      901 tcagaaaaca gctccacaac accagaaagt ggttgtttga actctttgtc tagtgatgac
      961 acttcttcac tgaacaacag tcaagaccat ctaacagtcc cagacagagc ttctggatca
     1021 agaatgacag acagagacga aataaaatcg tccgaagacg atgagatgga gaaactgtac
     1081 aagtcattgg agcaggctag cctgtctcct cttggggacc ggcgaccttc aaccaagaag
     1141 gagctgagaa agtcttttgt gaagcgatgc aaaaacccat caataaacga gaagctgcac
     1201 aagatcagaa ccttgaacag cacattaaag tgcaaagaac atgatttggc tatgatcaac
     1261 cagctgctgg atgacccaaa gctgacagcc aggaagtaca gagagtggaa agtcatgaac
     1321 accctgctga tccaggacat ctatcagcag caggtacctc aggaccctga agtcacccct
     1381 caggaaatca tgaaccccac ctcttctgac tgtgtggaaa attctctttg agcagatgcc
     1441 gggaccctac ccccatttct gttactatgc cattctacag gatgctgcca agggcctaca
     1501 ttctgcttat aaggaaaccc catacccagt tcctgagaca tcatccatcc ctcccaagga
     1561 tgcaacccag gtgaagccag ttctgatgca gtgggaatcc tggctcccac atgtgacatt
     1621 cctaatactg gagtagagtg atggagttca tctgagcagg cacatcttct gtgctcctac
     1681 tgagagctag caggaatcct aggctttagg caggatgtca agtgggtaaa ccccctctgt
     1741 ttgctttcaa gagaattaca acctgccaca gacaaaaggc ccaatttcac tagggataat
     1801 aattcacatt attattttgt tttgcaaaag aagcatgtag aactgccttt ggtgggcagc
     1861 ggagttcttc aaaatattgc tagtggagga atttcctcct tattggtgac tggaactgga
     1921 cacatgttgg catttgtgga gcacaaggct ccttgtaacg ttgacgttct acttggtaga
     1981 gcaccttatt tgcagagtag agcatggtgg gggtggggta tgagagccca aggagaaggt
     2041 attcttcctg ttccactcag agggcagctt catatgttca tgctttgcct agggtagggg
     2101 atgtgattaa tgtgcccatt ccttacaatg tctaggagac agaccatcac atgaccattg
     2161 gagacattgg tgccccactc ccagcttctt tgaacagtgg taggatattg atacccacta
     2221 taaggaatgt tatattgagt tcatccctgc ctgtgctgcc tagacccagc atgagtttat
     2281 gtccagtttt cctgggatcc aaattcacaa ggttatttct gaattgttct taacttggaa
     2341 aagaacccag accagcaaaa caacaaacca gttaaacagg atcattttat ttttgtatgt
     2401 ttatgtgtca tatcgtgtga ggtgtgaaca gtggtctatg tttcttattt aaatatattt
     2461 atagaaatgc aaattatagt gttttaaaag aaaatgtact actattattt gttgtccaat
     2521 atatatatat attctagaag catatccttt ttgcttgaga aaaataagta tagtagtgac
     2581 ttactggaat tgtattgcac tatgatatat gaagaatgct caggaaatct tgagagaaaa
     2641 ccacaggagc atgtattaat acttactaat tttctgaatg ctttctttcc atttcctatc
     2701 ctcacctcca gagctcttaa atttcaatgc ctgttacaca tcattttctt aactagcacc
     2761 ttaggatagc tcttctattc ataaaggtta tgctttatga tatttatgcc acgaattata
     2821 gacccaaagg aacacatctc atgaactctt gggccaaata aaatacaagt aacacaattc
     2881 ccaactaaat atttataaaa ttaaagtttg tttttgaaga aatctcaaag aaaaacaata
     2941 tattaatcac aatgacaatt tctaaatcat aagcataatt cactaagtac ccatatgagt
     3001 ctcctctacc ctttgaaaat tgttgacata tatattcata tagcatcaaa tgtggcttga
     3061 caaattcata tagaagtagc cacctgatct atatctataa agtaaatata aagaattgtt
     3121 taatatttcc ctgtacttta ccaagacttt ttttatacac tgaaatgaaa aacaatcctt
     3181 gccttaagag agaaacatag accaggaagc aaagagaagc tacaggattc attaagttga
     3241 aagacgaagc gtcgagatga tctgggagag ggcacgctgg gtcttccacc tggatcccag
     3301 cagttgaaga ggctaatgcc tcttaggatt gattcctcct gcggccagca gctgtacgga
     3361 gggcaatgct taggggtaca cagtgaaagg aagcactggg ggaaggtgaa ttaactagaa
     3421 caaccttagc ctgtgaaaaa atattcactc atgtcttttt ttttttttag cagcaccaac
     3481 ttctaaattt ccatcttccc ccaagttgaa gccccgaact ctttatgagg gctgattgct
     3541 atatttaaat gctttccttt ggcttttcat ttatacccat ttaactgacc tttgaatgta
     3601 aactcttagt aacatacaga tctaaaggca aaattggttc atgagattgc gtgaccaagc
     3661 catagggtga tttttttttc cccatgcaac ttaaagaaag ccagagtcaa gtttctgctt
     3721 tggtagaacc agcctgctga acgttcccac gtcagtctca gctgtgtcct gtcttcctgg
     3781 acatgaacca accactccct gttccccagt tcagtagata aatacttttt cactctgtgc
     3841 taggcttagt tagggagtag gaggtgcttc tgtggataca cagcctccgc taggagggtg
     3901 aggacagaca ggagtaagca gaagagtggg tgacgtgtcc atagaccctt ggtgaagaga
     3961 aatcatgagg agccttccct tggcctcgag tctcttccct ggttcaagag atttgggaac
     4021 tgatctcttc tggttaatga ctgggacatg gattatggag agtcagtggt agcctagggg
     4081 agactgcctc tggaatgaac cagagcaact atctccggac accatggtgg atctttgagc
     4141 acaagtcttt cacatggtac tgttaaggat gaggattctc tgggtacttt tttccttggg
     4201 gctgggagaa ggatcttttc tttcctagtt tgaagaccca gataagagcc tggcgggaga
     4261 ccctcactaa ttgagatgtt gttaacaccc atggatcccg aatttttctg gtgtttggag
     4321 gatgtctgtc atttgtaaga gttcttagtt ttccccgtag ctttaatctg aggttagatt
     4381 cagagttcag aaaaaagatg ctggagtaaa caactgttag gattccaaca ggccaaagaa
     4441 gaggtcaggt ttggagtcag attttcagtg tgaacccatg ccttatattg atacaactct
     4501 ttgaagtttg caaactatgt tcccccttcc ctgcatccta ccaccccata ggctaaatcg
     4561 gggcaattgt gaactctggg tataatgaaa tgcctggctc aaagccccaa gtggtacagc
     4621 cagaatctga gtttgagttt caggtctgcc agtcctctct gtggaggagg aatgactgtc
     4681 tgggcatagc ctgctgggga accaatggtc tgacctggtt cccacgtcta ttacactgag
     4741 ttccgcacac tggctgctgc aaaggcttct gctggatccc cagaggcacg cactgctgtg
     4801 agcagtctct ccccaaaggt cctgctgcct tgtcactggg ttttctgaga actagggctt
     4861 gacctgatgt gtttccttta ttcccttctg tagaagacac tatgttacca ctgtgaggac
     4921 tttaaggcca gaggatagaa gtctttaaag ggatggaaat gcctattttt cttatttttc
     4981 cttttgagat gtgacctgcc atgtcaggta tcagagactt agggactaga aatgactcat
     5041 ggaatcattt cctcagggag gctccagacc agatcgtcat ggagagggaa caaaaggaaa
     5101 agcaaaatag ttttcagtct tttgaggaga ggcactctag caatgaaagc catatttcat
     5161 tttacggaca caggcgtctt tgtaaaaaga gaaagacact attttgacac agcaatacaa
     5221 atgatttggt acagagggtg actgttcaaa cgtcacatta tgttgaagcg ggtattgtgt
     5281 ccaaatgcag ttttagaatg tagttctgct tccggctaac agaataggat acgtgaagga
     5341 gatttctgat ctctttccca taaaacactt ctgtagacat gagacattca gtcccggatg
     5401 taggaggtga ctgcccacct aaggttttgt cacccataat agtaagagcc cctcacatta
     5461 gattttttac aaatctctgt gaagtggatg tggtagaggg atattctatt cacagaaacc
     5521 taaccttctc agccacacca tgccacatga aaatggaccc tgcatttcaa aaggaagttt
     5581 tccatttccc ttgttgtaaa gaaacttaat tgctctgtag tgatgtcttg ttagctctag
     5641 tccaaaggga agcatgcccc catggagaca tttaacatcc tgtaattgaa aaccatggtt
     5701 taagtcacca catgttctgc tattgcatgg tggggatggg gttcaacagt gcatggtatt
     5761 ggggcaagat gttaacgtgg ggttgatacc ttatctgtca ttgtgctttt gatcattgtc
     5821 atctatctgt tttgacgaaa ctgaaaacac gaggcatgcc tcatttctcc tgttccctgt
     5881 tccccaggat gtcttgtaag ataaagataa aaagcaaact gtttagtaaa atggtatgaa
     5941 aaaaaagtca aaatacacta cttgtgttca
//
