LOCUS       NM_001191675            3415 bp    mRNA    linear   ROD 07-MAY-2024
DEFINITION  Rattus norvegicus integrator complex subunit 7 (Ints7), mRNA.
ACCESSION   NM_001191675 XM_223075
VERSION     NM_001191675.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3415)
  AUTHORS   Jodoin,J.N., Sitaram,P., Albrecht,T.R., May,S.B., Shboul,M.,
            Lee,E., Reversade,B., Wagner,E.J. and Lee,L.A.
  TITLE     Nuclear-localized Asunder regulates cytoplasmic dynein localization
            via its role in the integrator complex
  JOURNAL   Mol Biol Cell 24 (18), 2954-2965 (2013)
   PUBMED   23904267
REFERENCE   2  (bases 1 to 3415)
  AUTHORS   Cotta-Ramusino,C., McDonald,E.R. 3rd, Hurov,K., Sowa,M.E.,
            Harper,J.W. and Elledge,S.J.
  TITLE     A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1
            interacting protein required for ATR signaling
  JOURNAL   Science 332 (6035), 1313-1317 (2011)
   PUBMED   21659603
REFERENCE   3  (bases 1 to 3415)
  AUTHORS   Baillat,D., Hakimi,M.A., Naar,A.M., Shilatifard,A., Cooch,N. and
            Shiekhattar,R.
  TITLE     Integrator, a multiprotein mediator of small nuclear RNA
            processing, associates with the C-terminal repeat of RNA polymerase
            II
  JOURNAL   Cell 123 (2), 265-276 (2005)
   PUBMED   16239144
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000013.1.
            
            On Jul 17, 2010 this sequence version replaced XM_223075.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643292.50709.1,
                                           SRR26643287.29695.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-157               JAXUCZ010000013.1  105686208-105686364
            158-287             JAXUCZ010000013.1  105692951-105693080
            288-434             JAXUCZ010000013.1  105693735-105693881
            435-572             JAXUCZ010000013.1  105697179-105697316
            573-619             JAXUCZ010000013.1  105701866-105701912
            620-819             JAXUCZ010000013.1  105703673-105703872
            820-942             JAXUCZ010000013.1  105705973-105706095
            943-1060            JAXUCZ010000013.1  105712595-105712712
            1061-1195           JAXUCZ010000013.1  105717447-105717581
            1196-1293           JAXUCZ010000013.1  105718786-105718883
            1294-1533           JAXUCZ010000013.1  105720640-105720879
            1534-1671           JAXUCZ010000013.1  105723354-105723491
            1672-1878           JAXUCZ010000013.1  105724646-105724852
            1879-2073           JAXUCZ010000013.1  105729989-105730183
            2074-2177           JAXUCZ010000013.1  105730535-105730638
            2178-2246           JAXUCZ010000013.1  105731355-105731423
            2247-2379           JAXUCZ010000013.1  105732821-105732953
            2380-2478           JAXUCZ010000013.1  105734828-105734926
            2479-2664           JAXUCZ010000013.1  105736353-105736538
            2665-3415           JAXUCZ010000013.1  105738217-105738967
FEATURES             Location/Qualifiers
     source          1..3415
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q27"
     gene            1..3415
                     /gene="Ints7"
                     /gene_synonym="RGD1308014"
                     /note="integrator complex subunit 7"
                     /db_xref="GeneID:289382"
                     /db_xref="RGD:1308014"
     exon            1..157
                     /gene="Ints7"
                     /gene_synonym="RGD1308014"
                     /inference="alignment:Splign:2.1.0"
     CDS             64..2967
                     /gene="Ints7"
                     /gene_synonym="RGD1308014"
                     /codon_start=1
                     /product="integrator complex subunit 7"
                     /protein_id="NP_001178604.1"
                     /db_xref="GeneID:289382"
                     /db_xref="RGD:1308014"
                     /translation="MASNSTKSFLADAGYGEQELDANSALMELDKGLRSGKLGEQCEA
                     VVRFPRLFQKYPFPILINSAFLKLADVFRVGNNFLRLCVLKVTQQSEKHLEKILNVDE
                     FVKRVFSVIHSNDPVARAITLRMLGSLASIIPERKNAHHSIRQSLDSHDNVEVEAAVF
                     AAANFSAQSKDFAVGICNKISEMIQGLATPVDLKLKLIPILQHMHHDAILASSARQLL
                     QQLVTSYPSTKMVIVSLHTFTLLAASSLVDTPKQIQLLLQYLKSDPRKAVKRLAVQDL
                     KLLASKTPHTWSKENIQALCECALHTPYDSLKLGMLSVLSTLSGTIAIKHYFSVAPGN
                     VGSSPRSSDLVKLAQECCYHSNRAIAAHGVRVLTNITVSCQEKDLLSLEQDAVFGLES
                     LLVLCSQDDSPGAQSTVKSALSCMVKLAKGRPHLSRSVVDTLLTQLHSSQDAARILMC
                     HCLAAIAMKLPVLGDGMLGDLVELYKVIGRSATDKQQELLVSLATVIFVASQKALSAE
                     VKAVIKQQLESVSSGWTVYRIARQASRMGNHDMARELYQSLLTQVASEHFYFWLNSLK
                     EFSHAEQCLTGLQEGSFSSALSCIAESLKFYHKGIASLTAASTPLNPLSFQCEFVKLR
                     IDLLQAFSQLICTCNSLKTSPPPAIATTIAMTLGNDLQRCGRISNQMKQSMEEFRSLA
                     SRYRDLYQASFDADSATLRNVELQQQSCLLIAHAIEALVLDPESASFQEYGSTGAAHA
                     DSEYERRMMSVYSHVLEEVESLNRKYAPVSYMHTACLCNAIIALLKVPLSFQRYFFQK
                     LQSTSIKLALSPSPRNPAEPIAVQNNQQLALKVEGVVQHGSKPGLFRRIQSVCLNVSS
                     TLQSKSSQDYKIPVDSMTNEMEQRVEPHNDYFSTQFLLNFAVLGTHSITVESSVRDAN
                     GIVWKTGPRTTMFVKSLEDPYSQQIRLQQQQAQQPLQPQPQPQPQPRGAYTRF"
     exon            158..287
                     /gene="Ints7"
                     /gene_synonym="RGD1308014"
                     /inference="alignment:Splign:2.1.0"
     exon            288..434
                     /gene="Ints7"
                     /gene_synonym="RGD1308014"
                     /inference="alignment:Splign:2.1.0"
     exon            435..572
                     /gene="Ints7"
                     /gene_synonym="RGD1308014"
                     /inference="alignment:Splign:2.1.0"
     exon            573..619
                     /gene="Ints7"
                     /gene_synonym="RGD1308014"
                     /inference="alignment:Splign:2.1.0"
     exon            620..819
                     /gene="Ints7"
                     /gene_synonym="RGD1308014"
                     /inference="alignment:Splign:2.1.0"
     exon            820..942
                     /gene="Ints7"
                     /gene_synonym="RGD1308014"
                     /inference="alignment:Splign:2.1.0"
     exon            943..1060
                     /gene="Ints7"
                     /gene_synonym="RGD1308014"
                     /inference="alignment:Splign:2.1.0"
     exon            1061..1195
                     /gene="Ints7"
                     /gene_synonym="RGD1308014"
                     /inference="alignment:Splign:2.1.0"
     exon            1196..1293
                     /gene="Ints7"
                     /gene_synonym="RGD1308014"
                     /inference="alignment:Splign:2.1.0"
     exon            1294..1533
                     /gene="Ints7"
                     /gene_synonym="RGD1308014"
                     /inference="alignment:Splign:2.1.0"
     exon            1534..1671
                     /gene="Ints7"
                     /gene_synonym="RGD1308014"
                     /inference="alignment:Splign:2.1.0"
     exon            1672..1878
                     /gene="Ints7"
                     /gene_synonym="RGD1308014"
                     /inference="alignment:Splign:2.1.0"
     exon            1879..2073
                     /gene="Ints7"
                     /gene_synonym="RGD1308014"
                     /inference="alignment:Splign:2.1.0"
     exon            2074..2177
                     /gene="Ints7"
                     /gene_synonym="RGD1308014"
                     /inference="alignment:Splign:2.1.0"
     exon            2178..2246
                     /gene="Ints7"
                     /gene_synonym="RGD1308014"
                     /inference="alignment:Splign:2.1.0"
     exon            2247..2379
                     /gene="Ints7"
                     /gene_synonym="RGD1308014"
                     /inference="alignment:Splign:2.1.0"
     exon            2380..2478
                     /gene="Ints7"
                     /gene_synonym="RGD1308014"
                     /inference="alignment:Splign:2.1.0"
     exon            2479..2664
                     /gene="Ints7"
                     /gene_synonym="RGD1308014"
                     /inference="alignment:Splign:2.1.0"
     exon            2665..3415
                     /gene="Ints7"
                     /gene_synonym="RGD1308014"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tggcggtgca ggggaagagt ttgcaatctt tgtgactagg cgagtccggt aactataagg
       61 atcatggcgt caaactcaac caagtctttc ctggccgatg ccggctatgg cgaacaggag
      121 ctggacgcta actccgctct tatggaactg gacaaaggtc tgaggtctgg caaactcggg
      181 gagcagtgtg aagcggtcgt gcgctttccc aggcttttcc agaagtaccc gttccctatt
      241 ctcatcaatt cagcgttcct aaagttagct gacgttttca gagttggaaa caacttcctg
      301 cggctgtgtg ttctcaaagt gacccagcaa agtgaaaagc acctggagaa gattctaaac
      361 gtggatgaat ttgtgaagag ggttttctcg gtgattcaca gtaatgaccc tgtggcgaga
      421 gccatcaccc tacggatgtt gggaagtctg gcgtcaatca tccctgagag gaagaatgcc
      481 caccacagca tccgtcagag tctggactcc catgacaatg tagaagttga agctgctgtc
      541 tttgcagccg caaacttctc ggcacagtca aaggattttg ctgtggggat ctgtaacaaa
      601 atcagcgaaa tgattcaagg cttagctaca ccagtggacc tgaagctgaa actgatcccc
      661 atcctgcagc acatgcacca tgatgccatc ttggcctcca gtgcccgcca gctcctgcag
      721 cagctggtca cctcataccc ctccaccaaa atggtcatcg tgtctctaca cactttcact
      781 ctgctcgcag cctcctcttt ggttgacaca cccaagcaga ttcaacttct gctgcagtat
      841 ttgaagagcg accccaggaa agctgtgaag agacttgctg ttcaggatct gaagctgctc
      901 gctagtaaga caccacacac gtggagtaaa gagaacattc aggcactctg tgagtgtgca
      961 ctgcatactc cttatgacag cttgaagcta gggatgttgt ctgtcctctc cacactgtca
     1021 gggaccatcg ccattaaaca ttacttcagt gtggctccag gaaatgtagg ctcgtccccc
     1081 agatcttctg atttagtcaa attagcccaa gaatgctgtt accatagcaa cagggccatt
     1141 gcagcacatg gagtgagagt gctgactaat ataactgtgt cttgtcaaga aaaagatctc
     1201 ttgtctctgg agcaagatgc tgtctttggc ctggaatccc ttctggtgct ttgtagtcaa
     1261 gatgacagtc caggtgctca gtccactgtg aagagtgctc tcagctgtat ggtgaagctg
     1321 gccaagggcc gcccacattt gagccggtca gtggttgaca ctctgctaac tcagctgcac
     1381 agctctcagg atgctgcccg gatcctcatg tgccactgcc tggcagccat tgccatgaag
     1441 ctcccagtac tgggtgatgg aatgcttggt gacctcgtgg agctctacaa ggtgattgga
     1501 cgatcagcca cagacaagca acaggagctt ctggtaagtt tggctactgt gattttcgta
     1561 gccagccaga aagcattgtc tgcggaagta aaggcagtaa tcaagcagca acttgaaagc
     1621 gtctccagtg ggtggaccgt ataccggatt gccaggcagg cttccagaat gggcaaccat
     1681 gacatggccc gagagctcta ccagagtttg ctgacgcagg tcgcatcaga gcacttctac
     1741 ttctggctga acagtctgaa ggagttctca cacgcagagc agtgtctgac tgggctgcag
     1801 gagggtagct tcagctcagc actttcctgc attgctgagt ctttgaaatt ctaccacaaa
     1861 gggatcgcct ccttaacagc tgccagcacg ccactgaatc ctttaagctt tcagtgtgag
     1921 tttgtgaaac tcaggatcga tcttctccaa gccttctcgc aacttatttg tacttgtaac
     1981 agcctgaaga caagccctcc ccctgcgatc gccacgacga ttgccatgac cttagggaat
     2041 gatcttcaga ggtgtggccg gatctccaat cagatgaagc agtccatgga agagttccga
     2101 agccttgcct cccggtaccg ggatctctat caggcgtcct tcgatgcaga ctcggcaact
     2161 ctgaggaacg tagaactcca gcagcagagc tgcttactga tagcccacgc tatagaagcc
     2221 ctggttttgg atcctgaatc agcaagtttc caggagtatg ggtccacagg cgctgcccac
     2281 gcggacagcg agtatgagag aaggatgatg tccgtgtaca gccacgtcct agaggaggtg
     2341 gagtcgctta accggaagta cgccccagtt tcctacatgc acacagcatg cctctgcaat
     2401 gccatcatcg ctttgctgaa agttcctctc tcatttcaga gatacttttt ccagaaactg
     2461 cagtctacca gcatcaagct tgctctgtca ccctctcccc ggaaccctgc agagcccatt
     2521 gctgtacaga ataaccagca gctggcatta aaggtagaag gcgttgttca gcacgggtct
     2581 aaaccaggac tgttccgcag aatccaatct gtgtgtctga atgtttcttc tacactccag
     2641 agtaaatcca gccaggacta caagattccc gttgacagca tgaccaatga gatggagcag
     2701 agggtcgagc cacataatga ttacttcagc actcagtttc tgttgaactt cgctgtcctt
     2761 ggaacgcaca gcattacagt ggagtcatca gtgagagatg ccaatggcat cgtctggaag
     2821 acgggtccca gaactaccat gtttgtcaaa tccctggaag acccctattc ccagcagatt
     2881 cgcctacagc agcagcaagc ccagcagcct ttgcagccac agccgcagcc gcagccgcag
     2941 cctcgcggtg cctacacccg gttttagctg tgccacaagc atgcggctac cacactgcac
     3001 agccgtcaga ctacaggaag aatcttatcc ccgtgtgcat taagtgtgaa tgctacagtg
     3061 tgaaatccag tactcactga tttctgtaat gtagctttct ggtgattatt ttcttcttaa
     3121 aaatttagtg taagaaataa cctggctttt agccaaaaaa gtgcattttt cttttttttt
     3181 tttttttttt tttttggttc ttttttttcg gagctgggga ccgaacccag ggccttgcac
     3241 ttcctaggta agcgctctac cactgagcta aatccccagc ccctcttttt tatttcttaa
     3301 acccagtctt cgcctcacac ttagcatttt tgttgtatta ttctttgtgg tcggtgagat
     3361 tttcttcttc taagaatagt cacagatctt tggtaaattt gactatgtct ctgcc
//
