LOCUS       NM_001107576            3274 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus integrator complex subunit 5 (Ints5), mRNA.
ACCESSION   NM_001107576 XM_001073616 XM_219563
VERSION     NM_001107576.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3274)
  AUTHORS   Jodoin JN, Sitaram P, Albrecht TR, May SB, Shboul M, Lee E,
            Reversade B, Wagner EJ and Lee LA.
  TITLE     Nuclear-localized Asunder regulates cytoplasmic dynein localization
            via its role in the integrator complex
  JOURNAL   Mol Biol Cell 24 (18), 2954-2965 (2013)
   PUBMED   23904267
REFERENCE   2  (bases 1 to 3274)
  AUTHORS   Ghosh D, Lippert D, Krokhin O, Cortens JP and Wilkins JA.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   3  (bases 1 to 3274)
  AUTHORS   Baillat D, Hakimi MA, Naar AM, Shilatifard A, Cooch N and
            Shiekhattar R.
  TITLE     Integrator, a multiprotein mediator of small nuclear RNA
            processing, associates with the C-terminal repeat of RNA polymerase
            II
  JOURNAL   Cell 123 (2), 265-276 (2005)
   PUBMED   16239144
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473953.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_219563.4, XM_001073616.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ226934.1, FQ162684.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3274
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..3274
                     /gene="Ints5"
                     /gene_synonym="RGD1309370"
                     /note="integrator complex subunit 5"
                     /db_xref="GeneID:309200"
                     /db_xref="RGD:1309370"
     exon            1..144
                     /gene="Ints5"
                     /gene_synonym="RGD1309370"
                     /inference="alignment:Splign:2.1.0"
     CDS             65..3124
                     /gene="Ints5"
                     /gene_synonym="RGD1309370"
                     /codon_start=1
                     /product="integrator complex subunit 5"
                     /protein_id="NP_001101046.1"
                     /db_xref="GeneID:309200"
                     /db_xref="RGD:1309370"
                     /translation="MSALCDPPGAPGPPGPAPATHGPAPLSAQELSQEIKAFLTGADP
                     ILGHQLSAREHARCSLLLLRSLPPARAAVLDHLRGVFDESVRAHLAALEESPVAGPPH
                     LRPPPSSHVPAGGPGLEDVVHEVQQVLCEFIRANPKAWAPVISAWSIDLMGQLSSTYS
                     GQHQRVPHATGSLNELLQLWMGCRATRTLMDIYVQCLSALIGSCPDACVDALLDTSVQ
                     HSPHFDWVVAHIGSSFPGTIISRVLSCGLKDFCVHSGAGGGASACGGSSSQTPSSDPF
                     PGSPAIPGEKRVPKIASVVGILGHLASRHGDSIRRELLRMFHDSLSGGTGGRNGEPSL
                     QATVPFLLQLAVMSPALLGTVSGELVDCLKPPAVLSQLQQHLQGFPREELDNMLNLAV
                     HLVSQASGTGAYRLLQFLVDTAMPASVITTQGLAVPDTVREACDRLIQLLLLHLQKLV
                     HHRGGSPGEGVLGPPPPPRPVPFLDALRNHVGELCGETLRLERKRFLWQHQLLGLLSV
                     YTRPSCGPEALGHLLSRARSPEELSLATQLYAGLVVSLSGLLPLAFRSCLARVHAGTL
                     QPPFTARLLRNLALLVGWEQQGGEGPSTLGARFGESASAHLSDLAPLLLHPEEEVAEA
                     AASLLAICPFPSEALSPSQLLGLVRAGVHRFFASLRLHGPPGVASASQLLTRLSQTSP
                     AGLKAVLQLLVEGALHRGNTELFGGEMDGDNETLSIVSTPLASASLLDINRRHTAAVP
                     GPGGIWSVFHAGVIGRGLKPPKIVQSRNHQEVIYNTQSLVNLLVHCCSASGSNEREGC
                     WGAPTLSPEAAKAVAVTLVESVCPDAAGAELAWPPEDHARATVERDLRIGRRFREQPL
                     LFELLKLVAAAPPALCYCSVLLRGLLAALLSHWEASRHPDTTHSPWHLEASCILVAVM
                     AEGSLLPPALGNMHEVFSQLAPFEVRLLLLSVWGFLREHGPLPQKFIFQSERGRFIRD
                     FSREGGGEGGPHLSVLHSVLHRNIDRLGLFSGRFQAPPPSTLLRQGT"
     exon            145..3274
                     /gene="Ints5"
                     /gene_synonym="RGD1309370"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcagcgcgc atgcgtcgcc tgtgcttcgc cgctcccgcc tcaggctccg ggtagggctc
       61 cgggatgtcc gcgttgtgcg accctcccgg ggccccaggg ccacccgggc ctgcccccgc
      121 cacccacggt cccgcgcctc tcagtgctca ggagctgtcc caagaaatca aggcttttct
      181 gacaggtgca gaccctattc tgggccacca gctctcagct cgtgaacatg ctcggtgcag
      241 tcttctcctg ctccgttctt tgccacctgc tcgggctgct gtgttggatc acttgagagg
      301 tgtttttgat gaaagtgtcc gggcccacct agctgcccta gaagaaagtc ctgtggctgg
      361 tccacctcac ctccgtccac ctccatcatc ccatgtccct gctggtggac ctggcttaga
      421 ggatgtggta catgaagtgc agcaggtgct atgtgagttt atccgtgcca acccaaaggc
      481 ctgggcacct gtgattagtg catggtccat tgacctcatg ggacaactga gcagcacata
      541 ttcaggtcag catcaacgtg ttccccatgc cactggctct ctcaatgaac tgttgcagct
      601 ttggatgggc tgcagggcca cccgcacatt aatggacatc tatgtgcagt gcctctcagc
      661 tctcattggt agctgcccag atgcatgtgt agatgccttg ctggacactt ctgttcagca
      721 ttccccacac tttgactggg ttgtggccca cattggctct tcttttcctg gtaccatcat
      781 ctcccgagtc ctctcctgtg gccttaagga cttctgtgtc cacagtgggg ctggaggagg
      841 agctagtgct tgtggtggaa gctcttctca aaccccctct tcagacccct tccctggatc
      901 tcctgccata cctggggaaa aacgggtacc caagattgcc tcagttgtag gcattctagg
      961 gcacttggct tcccgccatg gagacagcat ccgacgggaa ctgttgcgca tgttccatga
     1021 tagcttgtca gggggtactg ggggccggaa tggggagccc tctcttcagg ctacagttcc
     1081 cttcctactg cagctggcag tcatgtcacc agctttgcta ggaacagtat ctggagaact
     1141 tgtggactgc ctcaagcccc cagcagtgct aagccagctg caacaacacc tgcaggggtt
     1201 cccccgagaa gagctagaca acatgctaaa cctggctgtg catctagtga gccaggcctc
     1261 tgggactggt gcctaccgcc tgctgcagtt cttagtggac acagctatgc ctgcttcagt
     1321 tattaccacc cagggcctgg ctgtgccaga cactgtaaga gaggcctgtg accgtctgat
     1381 ccagctgctt ttgctacatc tacaaaaact ggttcatcat cggggagggt ctcctggaga
     1441 aggggtgctg ggcccacccc cacctcctcg tccagtgccc tttcttgatg cattacgaaa
     1501 ccatgtagga gagctgtgtg gagagacact acggctagaa cggaagcgct tcctctggca
     1561 gcatcagctc ctgggcctac tgtctgtcta cactcgacct agctgtggac ctgaggcttt
     1621 gggccatctc ctgagcagag ccagaagccc tgaagagttg agtttggcaa cccagctata
     1681 cgcagggcta gtggttagtc tctctggcct tcttcccctg gccttccgaa gctgcctggc
     1741 ccgagtgcat gcagggactt tacagcctcc cttcacagcc cggcttctgc gcaatttggc
     1801 cttgttggtg gggtgggagc agcagggggg tgagggccct tcaaccttag gggcccggtt
     1861 tggggagtct gcctcagccc acctgtctga tctggctcct ctcctactcc atccagagga
     1921 ggaagtagct gaagctgctg cctccctcct tgcaatatgt ccctttcctt cagaagcttt
     1981 gtccccttcc caacttttgg gactagtgag agctggggta caccgcttct ttgcttctct
     2041 aaggctgcat ggccctcctg gtgtggcttc agcctcccag cttcttaccc gcctttctca
     2101 gacttcccca gctggactca aggctgtctt acagctgcta gttgagggag ccttacatcg
     2161 gggcaacacg gaactgtttg gaggggaaat ggatggagac aatgagactc tctcaattgt
     2221 ctcaacccca ttggcttctg cctctttgtt ggacattaac cggaggcata ctgcagctgt
     2281 gccgggtcct ggagggatct ggtcagtttt ccacgctgga gttatcggcc gtggcttaaa
     2341 gccacctaaa attgttcaat ctcgaaacca tcaggaagtt atctataaca ctcagagcct
     2401 tgttaacctc ctagtgcact gctgcagcgc atctgggagc aatgagcgtg agggttgctg
     2461 gggggctccc accctgagcc cagaggcagc caaagcagtt gcagtgacct tagtagagag
     2521 cgtgtgtcct gatgcagctg gtgctgagct ggcctggccc ccagaggatc acgcacgagc
     2581 caccgtggag cgggatctcc gcattggtcg gcgcttccgg gaacaacccc tgctgtttga
     2641 gcttttgaag ctggtagcag ctgctccccc agccctgtgc tactgctccg tgctgctgcg
     2701 ggggctgctg gctgccctct tgagccattg ggaagcctct cgacaccctg atacaaccca
     2761 ttccccctgg catctggagg catcctgtat cctggtggct gtcatggctg agggaagcct
     2821 cttgccacca gccctgggta atatgcatga ggtatttagc caactggcac cttttgaagt
     2881 tcgtctgttg ctgcttagtg tctggggttt tcttcgggag catgggccct tgccccagaa
     2941 gttcatcttc cagtcagagc gtggccgctt catccgggac ttttccaggg agggtggagg
     3001 tgaaggagga ccccatctgt ctgtgctgca cagtgtcctc caccgcaaca tcgatcgcct
     3061 ggggctcttc tctggccgtt ttcaggcacc tccaccatct actctgcttc ggcaggggac
     3121 ttgacctttt ctctacaagt tgtgcgaggt taaactgaga gaagagacta aggtgctaca
     3181 gaagggtgga ggcttctaag tccgtacgta atgagtggtg tcactttttt caaaccccac
     3241 cattttttct aaataaaatt tgccgagttg acac
//
