LOCUS       NM_001191629            3154 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus integrator complex subunit 4 (Ints4), mRNA.
ACCESSION   NM_001191629 XM_218937
VERSION     NM_001191629.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3154)
  AUTHORS   Jodoin,J.N., Sitaram,P., Albrecht,T.R., May,S.B., Shboul,M.,
            Lee,E., Reversade,B., Wagner,E.J. and Lee,L.A.
  TITLE     Nuclear-localized Asunder regulates cytoplasmic dynein localization
            via its role in the integrator complex
  JOURNAL   Mol Biol Cell 24 (18), 2954-2965 (2013)
   PUBMED   23904267
REFERENCE   2  (bases 1 to 3154)
  AUTHORS   Baillat,D., Hakimi,M.A., Naar,A.M., Shilatifard,A., Cooch,N. and
            Shiekhattar,R.
  TITLE     Integrator, a multiprotein mediator of small nuclear RNA
            processing, associates with the C-terminal repeat of RNA polymerase
            II
  JOURNAL   Cell 123 (2), 265-276 (2005)
   PUBMED   16239144
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Jul 17, 2010 this sequence version replaced XM_218937.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR22582424.1997750.1,
                                           SRR26360186.2481049.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-121               JAXUCZ010000001.1  161201284-161201404
            122-316             JAXUCZ010000001.1  161205459-161205653
            317-434             JAXUCZ010000001.1  161207812-161207929
            435-541             JAXUCZ010000001.1  161212366-161212472
            542-727             JAXUCZ010000001.1  161216994-161217179
            728-778             JAXUCZ010000001.1  161218587-161218637
            779-867             JAXUCZ010000001.1  161219853-161219941
            868-988             JAXUCZ010000001.1  161220607-161220727
            989-1060            JAXUCZ010000001.1  161226932-161227003
            1061-1235           JAXUCZ010000001.1  161228713-161228887
            1236-1441           JAXUCZ010000001.1  161230411-161230616
            1442-1584           JAXUCZ010000001.1  161234531-161234673
            1585-1700           JAXUCZ010000001.1  161239468-161239583
            1701-1834           JAXUCZ010000001.1  161240841-161240974
            1835-1992           JAXUCZ010000001.1  161242254-161242411
            1993-2086           JAXUCZ010000001.1  161250160-161250253
            2087-2167           JAXUCZ010000001.1  161252642-161252722
            2168-2298           JAXUCZ010000001.1  161253821-161253951
            2299-2358           JAXUCZ010000001.1  161254270-161254329
            2359-2518           JAXUCZ010000001.1  161256469-161256628
            2519-2662           JAXUCZ010000001.1  161256850-161256993
            2663-2783           JAXUCZ010000001.1  161261202-161261322
            2784-3154           JAXUCZ010000001.1  161264672-161265042
FEATURES             Location/Qualifiers
     source          1..3154
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q32"
     gene            1..3154
                     /gene="Ints4"
                     /gene_synonym="RGD1305036"
                     /note="integrator complex subunit 4"
                     /db_xref="GeneID:308837"
                     /db_xref="RGD:1305036"
     exon            1..121
                     /gene="Ints4"
                     /gene_synonym="RGD1305036"
                     /inference="alignment:Splign:2.1.0"
     CDS             68..2962
                     /gene="Ints4"
                     /gene_synonym="RGD1305036"
                     /codon_start=1
                     /product="integrator complex subunit 4"
                     /protein_id="NP_001178558.1"
                     /db_xref="GeneID:308837"
                     /db_xref="RGD:1305036"
                     /translation="MAAHLKKRVYEEFTKVVQQQQEEITTKKLRLTKPSKSAALHIDL
                     CKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRLKIASLLGLLSK
                     TAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGSKLPENQATQVRLVDVACKHL
                     TDTSHGVRNKCLQLLGNLGSLEKSVTKDTEGLTARDVQKIIGDYFSDQDPRVRTAAIK
                     AMLQLHERGLKLHQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPIPSSNE
                     EIRLVDDAFGKICHMVSDGSWVVRVQAAKLLGSMEQVSSHFLEQTLDKKLMSDLRRKR
                     TAHERAKELYSSGEFSSGRKWGDDAPKEEIDTGAVNLIESGACGAFVHGLEDEMYEVR
                     IAAVEALCMLAQSSPSFAEKCLDFLVDMFNDEIEEVRLQSIHTMRKISNNITLREDQL
                     DTVLAVLEDSSRDIREALHELLCCTNVSTKEGIHLALVELLKNLTKYPTDRDSIWKCL
                     KFLGSRHPTLVLPLVPELLSTHPFFDTAEPDMDDPAYIAVLVLIFNAAKTCPTMPALF
                     SDHTLRHYAYLRDSLSHLVPALRLPGRKLVSSAVPSNITPHEDPSQQFLQQSLERVYS
                     VQHLDPQGAQELLEFTIRDLQRLGELQSELAGVADFSATYLQCQLLLIKALQEKLWNV
                     AAPLYLKQSDLASAAAKQIMEETYKMEFMYSGVENKQVVIIHHMRLQARALQLLVTAR
                     TTRGVDPLFGMCEKFLQEVDFFQRCFIADLPHLQDSFVDKLLDLMPRLMASKPGEVIK
                     ILQTMLRQSTFLHLPLPEQIHKASATIIEPAGESDNPLRFTSGLVVALDVDATLEHVQ
                     DPQNSVKVQVLYPDGQAQMIHPKPADFRNPGPGRHRLLTQVYLSHTAWTEPCQVEVRL
                     LLAYNSGARIPKSPWLEGSEMSPQVETSIEGTIPFSKPVKVYIMPKPARR"
     exon            122..316
                     /gene="Ints4"
                     /gene_synonym="RGD1305036"
                     /inference="alignment:Splign:2.1.0"
     exon            317..434
                     /gene="Ints4"
                     /gene_synonym="RGD1305036"
                     /inference="alignment:Splign:2.1.0"
     exon            435..541
                     /gene="Ints4"
                     /gene_synonym="RGD1305036"
                     /inference="alignment:Splign:2.1.0"
     exon            542..727
                     /gene="Ints4"
                     /gene_synonym="RGD1305036"
                     /inference="alignment:Splign:2.1.0"
     exon            728..778
                     /gene="Ints4"
                     /gene_synonym="RGD1305036"
                     /inference="alignment:Splign:2.1.0"
     exon            779..867
                     /gene="Ints4"
                     /gene_synonym="RGD1305036"
                     /inference="alignment:Splign:2.1.0"
     exon            868..988
                     /gene="Ints4"
                     /gene_synonym="RGD1305036"
                     /inference="alignment:Splign:2.1.0"
     exon            989..1060
                     /gene="Ints4"
                     /gene_synonym="RGD1305036"
                     /inference="alignment:Splign:2.1.0"
     exon            1061..1235
                     /gene="Ints4"
                     /gene_synonym="RGD1305036"
                     /inference="alignment:Splign:2.1.0"
     exon            1236..1441
                     /gene="Ints4"
                     /gene_synonym="RGD1305036"
                     /inference="alignment:Splign:2.1.0"
     exon            1442..1584
                     /gene="Ints4"
                     /gene_synonym="RGD1305036"
                     /inference="alignment:Splign:2.1.0"
     exon            1585..1700
                     /gene="Ints4"
                     /gene_synonym="RGD1305036"
                     /inference="alignment:Splign:2.1.0"
     exon            1701..1834
                     /gene="Ints4"
                     /gene_synonym="RGD1305036"
                     /inference="alignment:Splign:2.1.0"
     exon            1835..1992
                     /gene="Ints4"
                     /gene_synonym="RGD1305036"
                     /inference="alignment:Splign:2.1.0"
     exon            1993..2086
                     /gene="Ints4"
                     /gene_synonym="RGD1305036"
                     /inference="alignment:Splign:2.1.0"
     exon            2087..2167
                     /gene="Ints4"
                     /gene_synonym="RGD1305036"
                     /inference="alignment:Splign:2.1.0"
     exon            2168..2298
                     /gene="Ints4"
                     /gene_synonym="RGD1305036"
                     /inference="alignment:Splign:2.1.0"
     exon            2299..2358
                     /gene="Ints4"
                     /gene_synonym="RGD1305036"
                     /inference="alignment:Splign:2.1.0"
     exon            2359..2518
                     /gene="Ints4"
                     /gene_synonym="RGD1305036"
                     /inference="alignment:Splign:2.1.0"
     exon            2519..2662
                     /gene="Ints4"
                     /gene_synonym="RGD1305036"
                     /inference="alignment:Splign:2.1.0"
     exon            2663..2783
                     /gene="Ints4"
                     /gene_synonym="RGD1305036"
                     /inference="alignment:Splign:2.1.0"
     exon            2784..3154
                     /gene="Ints4"
                     /gene_synonym="RGD1305036"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggtgctgtag aaaggtttac ctccgcactc ttggcaagta cagtagccga gaaggtccgg
       61 cgcggccatg gcggcccacc tgaaaaagcg ggtgtatgaa gagttcacta aagtggttca
      121 gcaacagcag gaggaaatca ctactaagaa gctccgatta acaaaaccga gtaaatctgc
      181 tgctctccac atagatctat gtaaagccac ctccccagca gatgctttgc agtacctact
      241 ccagtttgcc aggaagccag tagaggcaga aagtgtggag ggggtagtca ggatcctctt
      301 ggaacattat tacaaggaaa atgatccatc tgtgagactg aaaatcgcat cgctgttggg
      361 attattatca aagactgcag gattctctcc agattgcata atggatgatg ccattaacat
      421 actacagaat gaaaagtctc atcaagttct agctcagcta ttagacactt tgcttgcaat
      481 tggcagtaaa ctcccagaaa atcaagctac ccaagtgcga ttagtggatg tggcctgcaa
      541 gcacctgaca gatacgtccc atggtgtcag aaataaatgt ctgcaattac ttggcaatct
      601 tggctctttg gagaaaagtg tcacaaaaga tactgaaggc ttaactgcca gagatgtcca
      661 gaagattatc ggggattact tcagtgacca agacccacgt gtcagaacag cagcgataaa
      721 agccatgttg cagctccatg aaagaggact gaagttacac caaacgattt ataatcaggc
      781 ctgtaaactg ctctctgacg actatgagca ggtgcgcagt gctgcggtcc agctaatctg
      841 ggtcgtcagc cagctctatc ctgagagtat cgttccaata ccttcttcta atgaagaaat
      901 ccgtctagtt gatgatgcat ttggaaaaat ttgccacatg gtcagtgatg gctcctgggt
      961 agttcgtgtt caagctgcaa agctattggg ctctatggag caagtcagtt ctcatttctt
     1021 ggaacagact cttgataaga agctgatgtc agatctgagg aggaaacgca ccgcacatga
     1081 gcgtgccaag gaactttaca gttcagggga gttttccagt ggcaggaaat ggggagatga
     1141 tgctcccaag gaagaaatag atacaggggc cgtgaacttg atagagtcag gagcctgtgg
     1201 agccttcgtt catgggctgg aagatgagat gtatgaagtt cgcattgctg ctgtggaggc
     1261 tctgtgtatg ctagcccagt cttcgccctc ttttgctgaa aagtgccttg acttcctcgt
     1321 tgacatgttc aatgatgaaa tcgaggaagt gcgtctgcag tccatacata ccatgagaaa
     1381 aatctctaac aatatcaccc tccgagaaga tcagctcgat actgtcctgg ctgtgttaga
     1441 ggattcatcc agggatatta gagaggctct tcatgaactc ttgtgctgca ctaatgtctc
     1501 aacaaaagaa gggattcatc ttgcactggt ggagctactg aaaaacctaa ccaagtaccc
     1561 tactgacagg gactccatat ggaagtgctt gaagtttctg ggaagccggc atccgaccct
     1621 ggtgcttccg ttggtgccag agctcttgag cactcaccca ttttttgaca ctgcggaacc
     1681 agacatggat gatccagctt acattgcagt tttagttctt atcttcaacg ctgctaaaac
     1741 ctgtcctaca atgccagcac tgttctcaga tcacaccctc cggcactatg cctacctccg
     1801 agacagcctt tctcaccttg ttcctgcctt gaggttacca gggagaaaat tggtgtcctc
     1861 cgctgtcccc tctaacatca ccccccatga agatccttcc cagcagttcc tgcagcagag
     1921 ccttgaacgg gtgtacagtg ttcagcacct ggaccctcag ggagcccagg agctgctgga
     1981 attcaccatc agagatctgc aaagacttgg agaacttcag tctgaattgg cgggggtagc
     2041 tgacttctcc gccacctatc ttcagtgtca actgctcctc attaaggcct tgcaggagaa
     2101 gctgtggaat gtggctgccc ccttgtatct aaagcagagt gatttggcct cagcagcagc
     2161 aaaacagatc atggaagaaa cctacaaaat ggagtttatg tatagtggtg tggaaaataa
     2221 gcaggttgtg atcatacacc acatgaggct tcaggccaga gctctgcagc ttctggtaac
     2281 tgcacggact acccgaggag ttgacccctt atttggaatg tgtgaaaaat ttttacagga
     2341 agtagatttc tttcagaggt gcttcattgc ggatttgccc catcttcaag atagctttgt
     2401 ggacaaactg cttgatctca tgccccgact catggcttct aagcctggag aagtgatcaa
     2461 gattctgcag acaatgctgc ggcaaagcac cttccttcat cttccgcttc cagagcagat
     2521 ccacaaagcc tcggccacca ttattgagcc agcaggagag tcagacaacc ctttgcggtt
     2581 tacatctggg ttggtggtag ccttggatgt ggatgcaacc ctggaacatg tgcaagaccc
     2641 ccagaacagt gtcaaggtcc aggtcttgta tccagatggc caggctcaga tgatccaccc
     2701 caagccagca gacttccgga atcctggccc agggcggcac cgtctcctca cgcaggtgta
     2761 tctctcccac actgcctgga cagaaccatg ccaagtggaa gtgaggctgt tgctggccta
     2821 caactctggt gcacgaattc caaaatctcc atggctggag ggtagtgaga tgtcaccaca
     2881 ggtggaaacc agcatcgagg gcaccatccc cttcagtaag cctgtgaaag tctacataat
     2941 gcccaagcct gcaagacgtt gacccacaag cagccatgga ctagaaaccc tttttaggca
     3001 ccagggagcc tcacctggaa gtgttgtgta tgtttaggct tgaagaacat gtaacccttg
     3061 cataccatac acaggaccaa tcatttctgc attaaaacca gaaatctgct ggtttatttc
     3121 ctctatcccc ataataaagt tgagaaaaca ccta
//
