LOCUS       XM_017591307            4525 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus integrator complex subunit 3 (Ints3),
            transcript variant X1, mRNA.
ACCESSION   XM_017591307
VERSION     XM_017591307.2
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051337.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_017591307.3.
            
            On Jan 21, 2021 this sequence version replaced XM_017591307.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4525
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4525
                     /gene="Ints3"
                     /note="integrator complex subunit 3; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 34 ESTs, 3 long SRA reads, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     81 samples with support for all annotated introns"
                     /db_xref="GeneID:361988"
                     /db_xref="RGD:1304593"
     CDS             662..3862
                     /gene="Ints3"
                     /codon_start=1
                     /product="integrator complex subunit 3 isoform X1"
                     /protein_id="XP_017446796.1"
                     /db_xref="GeneID:361988"
                     /db_xref="RGD:1304593"
                     /translation="MELQKGKGTVAAASSGAAGGGGGGAGAGAPGGGRLLLSTSLDAK
                     DELEERLERCMSIVTSMTAGVSEREANDALNAYVCKGPPQHEEICLGLFTLVLTEPAQ
                     AQKCYRDLALVSRDGMNIVLNKINQLLMEKYLKLQDTCRTQLVWLVRELVKSGVLGAD
                     GVCMTFMKQIAGGDVTAKNIWLAESVLDILTEQREWVLKSSILIAMAVYTYLRLIVDH
                     HGTAQLQTLRQKEVDFCISLLRERFMECLMIGRDLVRLLQNVARIPEFELLWKDIIHN
                     PQALSPQFTGILQLLQSRTSRKFLACRLTPDMETKLLFMTSRVRFGQQKRYQDWFQRQ
                     YLSTPDSQSLRCDLIRYICGVVHPSNEVLSSDILPRWAIIGWLLTTCTSNVAASNAKL
                     ALFYDWLFFSPDKDSIMNIEPAILVMHHSMKPHPAITATLLDFMCRIIPNFYPPLEGH
                     VRQGVFSSLNHIVEKRVLAHLAPLFDNPKLDKELRSMLREKFPEFCSSPSPPVEASFP
                     EASGILGSTRGYQESFFLYSQVKIEEPVSMEMDNHLSDKDESCYDNAEAAFSDDEEDL
                     NSKGKKREFRFHPIKETVVEEPVDVTPYLDQLDESLRDKVLQLQKGSDTEAQCEVMQE
                     IVDQVLEEDFDSEQLSVLASCLQELFKAHFRGEVLPEEVTEESLEESVGKPLYLIFRN
                     LCQMQEDNSSFSLLLDLLSELYQKQPKIGYHLLYYLRASKAAAGKMNLYESFAQATQL
                     GDLHTCLMMDMKACQEDDVRLLCHLTPSIYTEFPDETLRSGELLNMIVAVIDSAQLQE
                     LVCHVMMGNLVMFRKDSVLNILIQSLDWETFEQYCAWQLFLAHNIPLETVIPILQHLK
                     YKEHPEALSCLLLQLRREKPSEEMVKMVLSRPCHPDDQFTTSILRHWCMKHDELLAEH
                     IKALLIKNNSLPRKRQSLRSSSSKLAQLTLEQILEHLDNLRLNLANTKQNFFSQTPIL
                     QALQHVQASCDEAHKMKFSDLFSLAEEYEDSSTKPPKSRRKAALSSPRSRKNAAQPPN
                     AEEESGSSSASEEEDTKPKPTKRKRKGSSAVGSDSD"
ORIGIN      
        1 cagtctgtcg tcgtcggctt actccttaga gacctggcgc caccgcggaa gccgctattg
       61 gcggacgccc gggaccgcga ctgctcactt ccggcgccgg cgacgactct gcccgctcgg
      121 gcactctcag cctcccccgc ccttccacca tggccgcctc tgtgtggtgt ggggagaagc
      181 tggtcctccc gtagcgctcc ggccgcatcc tcacccgcta ggggccggat tccaaggaac
      241 cgcgtttccc aatcccgctg ggaaggtttc ccacccccaa ttcagggcca ggactccttc
      301 ccacacctcg agaggcagaa acttagggtc tcccctcctt tcaggataag aagccagagg
      361 gttccctctc cacttctgca agggtggcag ccttgcccac ctctctgcag ggcacaagac
      421 cctagtccca tacttctgcg ctaaagctct gccccagcac ggctactcca gagggagcat
      481 ctagagaacc cgcgtctttc ccctccgcag gagaggaggc aagagtgcgg aaagccaggc
      541 ctatcggcct ccctcccact tgttcctctt gctcctcgtc cttggcaagc cagagttctc
      601 catttctagg acttaacacc cgtctactcc cttgacctct tccggtctcc tggctgcagc
      661 catggagtta cagaagggaa aggggaccgt agcagctgct tcatcaggag cagcgggagg
      721 tggaggagga ggagcgggag caggagcccc aggagggggg aggctgctac tttcaaccag
      781 tttggatgcc aaggatgagt tagaggagag gttggaaagg tgtatgagta ttgtcacatc
      841 gatgactgct ggtgtctccg agagagaagc caatgatgcc ctcaatgcgt atgtgtgcaa
      901 aggacctccc cagcatgagg agatctgcct aggcctgttt actcttgtcc tcactgagcc
      961 tgcccaagcc cagaagtgtt accgggactt ggctctggtc agtcgtgatg gtatgaacat
     1021 tgtcctgaac aaaatcaacc agctacttat ggagaagtac ttgaagttgc aagatacctg
     1081 ccgtactcag ttggtgtggt tggttcggga actagtaaag agtggagttc tgggagctga
     1141 tggtgtttgc atgacattta tgaagcagat tgcaggtggt gatgttacag ccaaaaatat
     1201 ctggttggca gaaagtgttc tggatatcct gacggaacag agggagtggg tactgaagag
     1261 cagcatcctc attgccatgg ctgtgtacac gtacctccga ctcatcgtgg accaccatgg
     1321 gaccgcccag ctccagaccc ttcggcagaa ggaagtcgac ttctgtatct ccctgcttcg
     1381 ggaacggttc atggaatgtt tgatgattgg ccgggacctc gtaagattac ttcagaatgt
     1441 tgctaggata ccagaatttg aactgctttg gaaagatatc atacataacc ctcaggcctt
     1501 gagtcctcag tttacaggta tcctacagtt acttcagtca agaacatccc ggaaattttt
     1561 agcctgtcgt ctaaccccag acatggaaac gaagctgctc ttcatgacat cgagggtgcg
     1621 gtttggccag caaaagcgat accaggattg gttccagcgc cagtacctct caacccctga
     1681 cagtcagtct ctgcgctgtg acctcattcg atacatctgt ggggtagttc acccctctaa
     1741 cgaagtgctg agttctgata tcttgccccg atgggccatc attggctggc tcctgacaac
     1801 atgcacgtcc aatgttgctg cctccaatgc caagctggct ttgttttatg actggctgtt
     1861 cttcagccca gacaaggata gcattatgaa catagagcca gctattctgg tcatgcatca
     1921 ctccatgaag ccccacccag ccatcactgc cacgcttctg gacttcatgt gccgaatcat
     1981 ccctaacttc tacccaccgt tggaaggtca cgttcggcag ggcgtctttt cttctctcaa
     2041 ccacattgtg gagaaacgag tcttggcaca cttggctccc ctgtttgata accctaaatt
     2101 ggataaagag cttcggtcca tgcttcgaga gaagtttcct gagttctgca gctcaccctc
     2161 ccctcctgtg gaagcctcat ttccagaagc atctggtata ctggggagca caagaggcta
     2221 tcaggagtct ttttttcttt actcacaagt caaaattgaa gagcctgttt ccatggaaat
     2281 ggacaaccat ctgtcagata aggatgagag ttgctatgac aatgcagagg cagccttcag
     2341 tgatgatgag gaggatctta atagcaaagg gaagaagaga gaatttcgct tccaccccat
     2401 caaggagact gttgtggagg agccagttga tgtcacccct taccttgatc agttggatga
     2461 gtccctaagg gacaaagtgc tgcagctgca gaagggaagt gatacagagg cccagtgtga
     2521 ggtcatgcag gaaattgtgg atcaggtcct ggaggaagac tttgactcgg agcagctgtc
     2581 tgtccttgct tcctgcctac aggagctctt caaggcccac ttccgagggg aggtgctgcc
     2641 tgaagaggtc actgaagagt ccctggagga atcagtaggg aagcctctgt acctaatatt
     2701 taggaacctg tgccagatgc aggaggacaa cagcagcttt tcgctgcttc tggaccttct
     2761 ctccgagctg taccaaaagc agcccaagat tggctaccac ctgctttact acctgagggc
     2821 aagcaaagcc gccgcaggga agatgaacct gtacgagtca tttgcccagg ctacccagct
     2881 gggtgacctg cacacctgtc taatgatgga catgaaggct tgccaagagg atgatgtgcg
     2941 gctgctatgc cacctcacgc cttccatcta cacagagttt ccagatgaaa ccttaaggag
     3001 cggggagctg ctgaacatga tagtggctgt tattgactct gcacagctcc aggagctagt
     3061 ctgccatgtg atgatgggga acctggtcat gttccggaag gactcagtcc tcaacatact
     3121 cattcagagc ctggactggg aaacctttga gcagtattgt gcctggcagc tcttccttgc
     3181 ccacaacatc cctctggaga ctgtcatccc tattctgcag cacctcaaat acaaggagca
     3241 cccagaggcc ctgtcctgtc tcctgcttca gcttcgaaga gagaagccca gtgaggagat
     3301 ggtgaagatg gtgctgagcc ggccctgcca tcctgatgac cagttcacca ccagcatcct
     3361 gaggcactgg tgcatgaagc acgatgagct gcttgcagag cacatcaagg ccttgctcat
     3421 caagaacaac agccttcccc gcaagaggca gagcctaaga agctctagca gcaagctggc
     3481 ccagctgacc ctggaacaga tcctggaaca cttggacaac ctaagactca acctagccaa
     3541 caccaagcag aactttttta gccagacacc gatcctccag gcgctgcagc atgtccaggc
     3601 aagctgtgac gaagctcaca agatgaagtt cagtgacctc ttctccctgg ccgaggaata
     3661 tgaggactct tccactaagc cacccaagag ccggcggaag gcagctctgt ccagccctcg
     3721 aagtcgaaag aatgctgccc agcctcccaa tgctgaagaa gagtcgggct ccagcagtgc
     3781 ctcggaggaa gaagacacaa agcctaagcc caccaaacga aaacgaaaag gctcctctgc
     3841 tgtgggttct gacagtgact gaggcctggc attcccaccc tgccccagcc tgagaaacgt
     3901 ccacgcagcc ccacccctcc tcttatccca gggcctccag ctccttttac ccctctccac
     3961 tgctgctccc actggtaggt actcacagca gccagacgct gtgcagaagc agatcatggt
     4021 ggaagatctt gcccctggct cctccccaag tctccaaaga gccattggac agagaaggga
     4081 gtgatgaaga ggcttctggg cagagaagct gggacggcgg cagatgctgt gtgagtgggc
     4141 actccttcct gcttcccttc agtctgcatt tgttctgaac agacacttgt agtctgtgga
     4201 cggcggtcac tacaccagtg tgaaatgggc atctgacctg gtgtgggcgg tgcccatctg
     4261 ggcaaatgcc acagccttca gaaaagaacc tgatgacagc gtaagaggct cttgctgcac
     4321 ctgggatgct tgggttggcc cagcattggc acttcaagct gagccggagc ccaggggagt
     4381 cccggaggca agttcctcag aactgtcaaa tggcctgatt tctgtggttc tgtttttgct
     4441 ttttcttttg gcaaagataa tcgagtttta aattgttttt aagtgataat gaaacaagcc
     4501 agaacatctt ttgtgcctga gttga
//
