LOCUS       NM_001007640            2983 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus integrator complex subunit 12 (Ints12), mRNA.
ACCESSION   NM_001007640 XM_006233321 XM_227687
VERSION     NM_001007640.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2983)
  AUTHORS   Jodoin,J.N., Sitaram,P., Albrecht,T.R., May,S.B., Shboul,M.,
            Lee,E., Reversade,B., Wagner,E.J. and Lee,L.A.
  TITLE     Nuclear-localized Asunder regulates cytoplasmic dynein localization
            via its role in the integrator complex
  JOURNAL   Mol Biol Cell 24 (18), 2954-2965 (2013)
   PUBMED   23904267
REFERENCE   2  (bases 1 to 2983)
  AUTHORS   Baillat,D., Hakimi,M.A., Naar,A.M., Shilatifard,A., Cooch,N. and
            Shiekhattar,R.
  TITLE     Integrator, a multiprotein mediator of small nuclear RNA
            processing, associates with the C-terminal repeat of RNA polymerase
            II
  JOURNAL   Cell 123 (2), 265-276 (2005)
   PUBMED   16239144
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On or before Dec 20, 2022 this sequence version replaced
            XM_006233321.4, NM_001007640.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ212179.1, SRR26643290.10079.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-42                JAXUCZ010000002.1  224265787-224265828
            43-207              JAXUCZ010000002.1  224270381-224270545
            208-360             JAXUCZ010000002.1  224271188-224271340
            361-545             JAXUCZ010000002.1  224273340-224273524
            546-705             JAXUCZ010000002.1  224275951-224276110
            706-852             JAXUCZ010000002.1  224280226-224280372
            853-2983            JAXUCZ010000002.1  224281393-224283523
FEATURES             Location/Qualifiers
     source          1..2983
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q43"
     gene            1..2983
                     /gene="Ints12"
                     /gene_synonym="Phf22"
                     /note="integrator complex subunit 12"
                     /db_xref="GeneID:295448"
                     /db_xref="RGD:1359136"
     exon            1..42
                     /gene="Ints12"
                     /gene_synonym="Phf22"
                     /inference="alignment:Splign:2.1.0"
     exon            43..207
                     /gene="Ints12"
                     /gene_synonym="Phf22"
                     /inference="alignment:Splign:2.1.0"
     CDS             52..1437
                     /gene="Ints12"
                     /gene_synonym="Phf22"
                     /note="int12; PHD finger protein 22"
                     /codon_start=1
                     /product="integrator complex subunit 12"
                     /protein_id="NP_001007641.1"
                     /db_xref="GeneID:295448"
                     /db_xref="RGD:1359136"
                     /translation="MAATVNLELDPIFLKALGFLHSKSKDSAEKLKTLLDESLARGID
                     ASYRPAQKDVEPPKISSTKSLSIKQEPKTSSSLPSGSSNGKVLAAEKLKKEAEKRPAD
                     KMKDATEGVDVPKKPRLEKPETRSSPITVQTSKDLAMADLSSFEETSADDFAMEMGLA
                     CVVCRQMTVASGNQLVECQECHNLYHQDCHKPQVTDKEVNDPRLVWYCARCTRQMKRM
                     AQKTQKPPQKPAPTVVSVAPTVKDPLVKKPETKLKQETTFLAFKRTEVKPSTVISGNS
                     SSNNVSSSVTSGLTGWAAFAAKTSSAGPSTAKLNSTAQNSSGKPAASSASQKPVGLTG
                     LATSSKGGIGSKIGSSNSTSPSVPLKPLPPLTLGKTGLSRSVSCDNVSKVGLPSPSSL
                     VPGGSSQLSGNGNSATAGPTGSITSKTTSETSSSTSASLKGPTSQESQLNAMKRLQMV
                     KKKAAQKKLKK"
     exon            208..360
                     /gene="Ints12"
                     /gene_synonym="Phf22"
                     /inference="alignment:Splign:2.1.0"
     exon            361..545
                     /gene="Ints12"
                     /gene_synonym="Phf22"
                     /inference="alignment:Splign:2.1.0"
     exon            546..705
                     /gene="Ints12"
                     /gene_synonym="Phf22"
                     /inference="alignment:Splign:2.1.0"
     exon            706..852
                     /gene="Ints12"
                     /gene_synonym="Phf22"
                     /inference="alignment:Splign:2.1.0"
     exon            853..2983
                     /gene="Ints12"
                     /gene_synonym="Phf22"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaagagagct actgggaacc gaccgagtgc cggggcggag cggtgcttgc gatggctgcc
       61 actgtgaact tggaactcga tcccattttt ctgaaagcac taggtttctt acactcgaag
      121 agtaaagact ccgctgaaaa gctgaaaaca ctgctcgatg agtctctggc tcggggcatc
      181 gacgcaagtt accgtccagc tcaaaaggat gtggaaccgc ccaaaatttc aagtacaaaa
      241 tcgctttcta ttaagcaaga gcccaaaaca tcatccagcc tcccttctgg cagtagtaac
      301 ggcaaagtcc tcgcggctga gaagctaaag aaagaagccg agaagagacc tgcggacaaa
      361 atgaaagatg ccactgaagg agttgatgtt ccaaagaaac ctagattgga gaaaccagag
      421 acacgatcct ctcccatcac tgtccagacc agcaaggact tagctatggc tgacctctcc
      481 agctttgaag agaccagtgc tgatgacttt gccatggaga tgggattggc ctgtgttgtc
      541 tgtagacaaa tgacggtggc atctggaaac caattggttg aatgtcaaga gtgtcacaac
      601 ctctaccacc aagactgtca taagccccaa gtgacagaca aagaggtcaa tgaccctcgc
      661 ctggtgtggt attgtgcccg atgcaccaga caaatgaaga gaatggctca gaaaactcag
      721 aagccaccac agaaaccggc acccactgtt gtttctgtgg ctccgactgt caaggatcca
      781 ttagttaaga agccagaaac caaacttaaa caagagacaa ccttcctagc attcaagaga
      841 actgaagtta agccgtccac agttatttct ggaaattctt ctagtaacaa cgtgtcctct
      901 tcagtaacta gtggcctaac tggatgggca gcttttgcgg ccaaaacttc ttcagctggt
      961 ccatcaacag caaaattgaa ttcaacagcg caaaacagta gtggaaaacc tgctgcctca
     1021 tctgctagcc agaagcctgt gggtttgact ggtctggcaa cgtcatccaa aggtggaata
     1081 ggttccaaaa taggttctag taacagcact agcccctctg tcccgttgaa accgcttcct
     1141 cctctaacct taggcaagac tggcctgagt cgctcagtta gttgtgacaa cgtcagcaaa
     1201 gtgggacttc ctagccctag tagtttagtt cctggaggca gcagccaatt gagtgggaat
     1261 ggaaatagtg ccacagctgg gcccactgga agcatcacca gcaaaaccac atcagagacc
     1321 agcagcagca cctcagcgtc tcttaaaggt ccaacttccc aggaatctca gctcaacgca
     1381 atgaaacgat tacagatggt caagaagaaa gctgcccaaa agaaactcaa gaagtaatat
     1441 gggcagatag gtttttatat cctattacta taaaaaatta aaatctttac tgggacaaaa
     1501 gatgtaacat actgtaactt aataaaactc ttgatcaaat ctctattgtt tgttacatta
     1561 aaatgctaat atttagccaa acttggatct atttatttca gtctatttag catttttagt
     1621 ttccatagtg tgtgaaaaca gtgattataa tgactggtga cgagagcttc agaaaattga
     1681 tggcacatgc aaatgtaaag aaatggctct cctggtacct tatgggtggc agggaccact
     1741 caggagaaaa tgtcccagtg ttttatagta tctgaaatgt tcaatgtcag tcattgccct
     1801 tgtgtcagct gatctctctc tccaattact tcctctttta tcaaaattaa ttttgagaag
     1861 tgatttcccg tagctctcaa tcatgtcttt agctctcaat caccccttat cagttactta
     1921 gggagttatt tcttccagta gattatgaat gctcatgtct gcttaatact ttctcacgtt
     1981 ccccacttcc catacctgac cagtatgtgg atatgtgcac atatgtacat ttaataaatg
     2041 ctgactggac tcatcctggt tgcacattct gagaattaag aagagtatcc atttccaaga
     2101 ggttttgcag atgggaattt atgactagtt tatacacctt ccagtgaaag gacaggctgt
     2161 ttttaatact tcaagaatgt aataacattt taatgtggct taattatctt tgtatgaaag
     2221 aagctcctac caaattcttg agatttctat aagaaagtgt tcatgttttg aatattgtta
     2281 ggatatggat tgtctcctaa ggtttcatgt gttagaagca tgatccccag tacagttgga
     2341 gttggtggtt gacaggggga gcctgttcgg gggtcagaat gcccttggga aggattaatt
     2401 agttctcatg tgcccactga ctaatttggg caagagtggg gttataaaag gctatcccag
     2461 agttgactct tgggttactg tcttacggca aaatctctcc tctgaactgt tgccatgatg
     2521 caaacctata tgaggttgca tccagatcat tgtcttgtaa gctaacgaat tagccattag
     2581 tttacatata tatcccaaca gagaacagaa tgctttccgt atctgaccaa taaatgtact
     2641 acagcaaaat ggcatccttt cttttttaca atcaatgaat acctcatttt ttcccaaaac
     2701 tgaatcttgt gatttcctat attcgttgag ttgaattgtt ttaaatctaa tctcaatgtg
     2761 tctttttccc taggttttct aacatcatta tcctaaaata aattgataat tgttgtaaag
     2821 ttaaaattaa ttaactttta aattaagtgt gatctttttc tatggaaata ttttaaactg
     2881 taaaatagtg gcattaaatt gttcacaata aattagaagc caatattgaa ataaattgaa
     2941 aatttagaga tggaataaat atctatttat atacataaaa aaa
//
