LOCUS       NM_001033892            2036 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus integrator complex subunit 11 (Ints11), mRNA.
ACCESSION   NM_001033892 XM_216603
VERSION     NM_001033892.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2036)
  AUTHORS   Jodoin,J.N., Sitaram,P., Albrecht,T.R., May,S.B., Shboul,M.,
            Lee,E., Reversade,B., Wagner,E.J. and Lee,L.A.
  TITLE     Nuclear-localized Asunder regulates cytoplasmic dynein localization
            via its role in the integrator complex
  JOURNAL   Mol Biol Cell 24 (18), 2954-2965 (2013)
   PUBMED   23904267
REFERENCE   2  (bases 1 to 2036)
  AUTHORS   Bastos-Amador,P., Royo,F., Gonzalez,E., Conde-Vancells,J.,
            Palomo-Diez,L., Borras,F.E. and Falcon-Perez,J.M.
  TITLE     Proteomic analysis of microvesicles from plasma of healthy donors
            reveals high individual variability
  JOURNAL   J Proteomics 75 (12), 3574-3584 (2012)
   PUBMED   22516433
REFERENCE   3  (bases 1 to 2036)
  AUTHORS   Baillat,D., Hakimi,M.A., Naar,A.M., Shilatifard,A., Cooch,N. and
            Shiekhattar,R.
  TITLE     Integrator, a multiprotein mediator of small nuclear RNA
            processing, associates with the C-terminal repeat of RNA polymerase
            II
  JOURNAL   Cell 123 (2), 265-276 (2005)
   PUBMED   16239144
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1 and BC105303.1.
            
            On Jun 20, 2015 this sequence version replaced NM_001033892.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC105303.1, SRR26643429.22251.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-27                JAXUCZ010000005.1  171761405-171761431
            28-2036             BC105303.1         1-2009
FEATURES             Location/Qualifiers
     source          1..2036
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..2036
                     /gene="Ints11"
                     /gene_synonym="Cpsf3l; int11"
                     /note="integrator complex subunit 11"
                     /db_xref="GeneID:298688"
                     /db_xref="RGD:1306841"
     exon            1..138
                     /gene="Ints11"
                     /gene_synonym="Cpsf3l; int11"
                     /inference="alignment:Splign:2.1.0"
     CDS             108..1913
                     /gene="Ints11"
                     /gene_synonym="Cpsf3l; int11"
                     /EC_number="3.1.27.-"
                     /note="CPSF3-like protein; cleavage and
                     polyadenylation-specific factor 3-like protein; cleavage
                     and polyadenylation specific factor 3-like"
                     /codon_start=1
                     /product="integrator complex subunit 11"
                     /protein_id="NP_001029064.2"
                     /db_xref="GeneID:298688"
                     /db_xref="RGD:1306841"
                     /translation="MMPEIRVTPLGAGQDVGRSCILVSISGKNVMLDCGMHMGYNDDR
                     RFPDFSYITQSGRLTDFLDCVIISHFHLDHCGALPYFSEMVGYDGPIYMTHPTQAICP
                     ILLEDYRKIAVDKKGEANFFTSQMIKDCMKKVVAVHLHQTVQVDDELEIKAYYAGHVL
                     GAAMFQIKVGSESVVYTGDYNMTPDRHLGAAWIDKCRPNLLITESTYATTIRDSKRCR
                     ERDFLKKVHETVERGGKVLIPVFALGRAQELCILLETFWERMNLKVPIYFSTGLTEKA
                     NHYYKLFITWTNQKIRKTFVQRNMFEFKHIKAFDRTFADNPGPMVVFATPGMLHAGQS
                     LQIFRKWAGNEKNMVIMPGYCVQGTVGHKILSGQRKLEMEGRQMLEVKMQVEYMSFSA
                     HADAKGIMQLVGQAEPESVLLVHGEAKKMEFLRQKIEQEFRVSCYMPANGETVTLPTS
                     PSIPVGISLGLLKREMVQGLLPEAKKPRLLHGTLIMKDNNFRLVSSEQALKELGLAEH
                     QLRFTCRVHLQDTRKEQETALRVYSHLKSTLKDHCVQHLPDGSVTVESILIQAAAHSE
                     DPGTKVLLVSWTYQDEELGSFLTALLKNGLPQAPS"
     exon            139..236
                     /gene="Ints11"
                     /gene_synonym="Cpsf3l; int11"
                     /inference="alignment:Splign:2.1.0"
     exon            237..310
                     /gene="Ints11"
                     /gene_synonym="Cpsf3l; int11"
                     /inference="alignment:Splign:2.1.0"
     exon            311..539
                     /gene="Ints11"
                     /gene_synonym="Cpsf3l; int11"
                     /inference="alignment:Splign:2.1.0"
     exon            540..638
                     /gene="Ints11"
                     /gene_synonym="Cpsf3l; int11"
                     /inference="alignment:Splign:2.1.0"
     exon            639..673
                     /gene="Ints11"
                     /gene_synonym="Cpsf3l; int11"
                     /inference="alignment:Splign:2.1.0"
     exon            674..812
                     /gene="Ints11"
                     /gene_synonym="Cpsf3l; int11"
                     /inference="alignment:Splign:2.1.0"
     exon            813..877
                     /gene="Ints11"
                     /gene_synonym="Cpsf3l; int11"
                     /inference="alignment:Splign:2.1.0"
     exon            878..1067
                     /gene="Ints11"
                     /gene_synonym="Cpsf3l; int11"
                     /inference="alignment:Splign:2.1.0"
     exon            1068..1151
                     /gene="Ints11"
                     /gene_synonym="Cpsf3l; int11"
                     /inference="alignment:Splign:2.1.0"
     exon            1152..1241
                     /gene="Ints11"
                     /gene_synonym="Cpsf3l; int11"
                     /inference="alignment:Splign:2.1.0"
     exon            1242..1404
                     /gene="Ints11"
                     /gene_synonym="Cpsf3l; int11"
                     /inference="alignment:Splign:2.1.0"
     exon            1405..1512
                     /gene="Ints11"
                     /gene_synonym="Cpsf3l; int11"
                     /inference="alignment:Splign:2.1.0"
     exon            1513..1574
                     /gene="Ints11"
                     /gene_synonym="Cpsf3l; int11"
                     /inference="alignment:Splign:2.1.0"
     exon            1575..1717
                     /gene="Ints11"
                     /gene_synonym="Cpsf3l; int11"
                     /inference="alignment:Splign:2.1.0"
     exon            1718..1847
                     /gene="Ints11"
                     /gene_synonym="Cpsf3l; int11"
                     /inference="alignment:Splign:2.1.0"
     exon            1848..2009
                     /gene="Ints11"
                     /gene_synonym="Cpsf3l; int11"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtcgcggtgg ctgggtgtca ggtttgattg cgcgcgaggt ctaaggcttt cctgcgggcg
       61 gtgcgcgcga gctgtggaaa cgtggtttga gactgcctgc ctcctcgatg atgcctgaaa
      121 ttagggtcac tcccttgggg gctggccagg atgtaggccg cagctgtatc ttagtctcca
      181 tttcgggcaa gaatgtcatg ttggactgtg ggatgcacat gggctacaat gatgacaggc
      241 gctttcctga cttttcttac atcacccaga gtggccgtct gactgacttt ctggactgtg
      301 taatcatcag ccacttccac ctggaccact gtggggcact cccttacttc agtgaaatgg
      361 tgggctacga tgggcccatc tatatgaccc accctaccca ggccatctgc cccatcctgt
      421 tggaagacta ccgcaagatc gcagtggaca agaagggcga ggccaacttc ttcacttctc
      481 agatgatcaa agactgcatg aagaaggtgg tggctgttca cttgcaccag acagttcagg
      541 tggatgatga actggaaatc aaggcgtact atgcaggcca tgtgttgggg gcagccatgt
      601 tccagattaa agtgggctca gagtctgtgg tctacacggg tgattataac atgactccag
      661 accggcattt gggggctgct tggattgaca agtgtcgtcc caacctgctc atcacagagt
      721 ccacatatgc cacaaccatc cgagattcca aacgctgcag agagcgagac ttcctgaaga
      781 aagttcatga gactgtggag cgtggcggaa aggtgctgat ccctgtgttt gcgctgggcc
      841 gagcacaaga actctgcatc ctgctggaga ccttctggga gcgcatgaac ctgaaggtgc
      901 ccatctactt ctctacgggc ctgacagaga aagccaacca ttattacaag ctcttcatca
      961 cctggaccaa ccagaagatc cggaagacat ttgtccagag gaacatgttt gagtttaagc
     1021 acatcaaagc ctttgaccgg acatttgctg acaacccagg acccatggtt gtatttgcta
     1081 cacctgggat gctgcacgct ggccaatccc tgcagatctt ccgaaaatgg gcaggaaatg
     1141 agaagaacat ggtcatcatg cctggctact gtgtgcaagg tactgtgggc cacaagatcc
     1201 ttagtgggca acgcaagctg gaaatggaag ggcgtcagat gctggaggta aagatgcaag
     1261 tggagtacat gtccttcagt gcccacgccg acgccaaggg catcatgcag ctggtggggc
     1321 aggcagagcc cgagagtgtg ctgctggtgc atggcgaggc caagaagatg gagttcctga
     1381 ggcagaagat tgagcaggaa ttccgggtca gctgctacat gccagccaac ggtgagacag
     1441 tgacgctgcc cacaagcccc agcatccctg tgggcatctc cctcggactg ctgaagcgcg
     1501 agatggtaca gggactgttg cctgaagcca aaaaacctag gcttttacat ggcaccctaa
     1561 ttatgaaaga caataatttc cggctggtat cctcggagca agccctcaag gagttgggcc
     1621 tggccgaaca ccaactgcgc ttcacctgtc gtgtgcacct gcaggacaca cgcaaagaac
     1681 aagaaacagc cctacgtgtg tacagccatc tcaagagcac cctcaaggac cactgtgtac
     1741 agcatctccc ggatggctct gtgaccgtgg agtccattct tatccaagct gctgcccact
     1801 cagaggatcc tggtactaaa gtgcttctgg tctcctggac ttaccaagat gaggagctgg
     1861 gaagctttct cacagcattg ctcaaaaatg gccttcccca ggctcccagc tgacatgtat
     1921 ccaccagtaa cccaccgctg tggtctcttt cagttttccc agcatcagag tcataggctg
     1981 gctaaagtaa taaacaggcc tttttgttca aaaaaaaaaa aaaaaaaaaa aaaaaa
//
