LOCUS       NM_001134416            2428 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus integrator complex subunit 10 (Ints10), mRNA.
ACCESSION   NM_001134416 XM_001070525 XM_214334
VERSION     NM_001134416.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2428)
  AUTHORS   Jodoin JN, Sitaram P, Albrecht TR, May SB, Shboul M, Lee E,
            Reversade B, Wagner EJ and Lee LA.
  TITLE     Nuclear-localized Asunder regulates cytoplasmic dynein localization
            via its role in the integrator complex
  JOURNAL   Mol Biol Cell 24 (18), 2954-2965 (2013)
   PUBMED   23904267
REFERENCE   2  (bases 1 to 2428)
  AUTHORS   Baillat D, Hakimi MA, Naar AM, Shilatifard A, Cooch N and
            Shiekhattar R.
  TITLE     Integrator, a multiprotein mediator of small nuclear RNA
            processing, associates with the C-terminal repeat of RNA polymerase
            II
  JOURNAL   Cell 123 (2), 265-276 (2005)
   PUBMED   16239144
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB807605.1 and BC166856.1.
            
            [WARNING] On Mar 20, 2024 this sequence was replaced by
            NM_001134416.2.
            
            On or before Aug 29, 2008 this sequence version replaced
            XM_001070525.1, XM_214334.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166856.1, SRR8487227.338531.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-27                CB807605.1         1-27
            28-2428             BC166856.1         1-2401
FEATURES             Location/Qualifiers
     source          1..2428
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16p14"
     gene            1..2428
                     /gene="Ints10"
                     /gene_synonym="RGD1304711"
                     /note="integrator complex subunit 10"
                     /db_xref="GeneID:290679"
                     /db_xref="RGD:1304711"
     exon            1..155
                     /gene="Ints10"
                     /gene_synonym="RGD1304711"
                     /inference="alignment:Splign:2.1.0"
     CDS             27..2159
                     /gene="Ints10"
                     /gene_synonym="RGD1304711"
                     /codon_start=1
                     /product="integrator complex subunit 10"
                     /protein_id="NP_001127888.1"
                     /db_xref="GeneID:290679"
                     /db_xref="RGD:1304711"
                     /translation="MSAQGDCEFLVQRARELVPQDLWAAKAWLITARSLYPADFNIQY
                     EMYTIERNAERTATAGRLLYDMFVNFPDQPVVWREISIITSALRNDSQDKQTQFLRSL
                     FETLPGRVQCEMLLKVTEQCFNTLERSEMLLLLLRRFPETVVQHGVGLGEALLEAETI
                     EEQESPVNCFRKLFVCDVLPLIINNHDVRLPANLLYKYLNKAAEFYINYVTRSTQLEN
                     QHQGAPDTSDLMSPSKRSSQKYIIEGLTEKSSHIVDPWERLFKILNVVGMRCEWQMDK
                     GRRSCSDMLHRMKELCRYMNSFDSEAHTKYKNQVLYSTMLVLFKSAFQYISSIQPSLF
                     QGPNAPSQVPLVLLEDVANVYGDVEIDRSKHIHKKRKLAEGREKTMSSDDEECSAKGR
                     NRHIVVSKADLSNSIEVLESFKLARESWELLYSLEFLDKEFTRICLAWKTDTWLWLRI
                     FLTDMIIYQGQYKKAIASLHHLAALQGSLSQPQITGQGTLEHQRALIQLATCHFALGE
                     YRMTCEKVLDLMCYMVLPIQDGGKSQEEPSKVKPKCRKGLDLKLLPCTSKAIMPYCLH
                     LMLACFKLRAFTDNRDDMALGHVIVLLQQEWPRGENLFLKAISKICQQGNFQYENFFS
                     YVTNIDMLEEFAYLRTQEGGKIHLELLPNQGMLIKHHTVTRGITKGVKEDFRLAMERQ
                     VSRCGENLMVVLHRFCINEKILLLQTLT"
     exon            156..223
                     /gene="Ints10"
                     /gene_synonym="RGD1304711"
                     /inference="alignment:Splign:2.1.0"
     exon            224..327
                     /gene="Ints10"
                     /gene_synonym="RGD1304711"
                     /inference="alignment:Splign:2.1.0"
     exon            328..467
                     /gene="Ints10"
                     /gene_synonym="RGD1304711"
                     /inference="alignment:Splign:2.1.0"
     exon            468..549
                     /gene="Ints10"
                     /gene_synonym="RGD1304711"
                     /inference="alignment:Splign:2.1.0"
     exon            550..690
                     /gene="Ints10"
                     /gene_synonym="RGD1304711"
                     /inference="alignment:Splign:2.1.0"
     exon            691..862
                     /gene="Ints10"
                     /gene_synonym="RGD1304711"
                     /inference="alignment:Splign:2.1.0"
     exon            863..1032
                     /gene="Ints10"
                     /gene_synonym="RGD1304711"
                     /inference="alignment:Splign:2.1.0"
     exon            1033..1166
                     /gene="Ints10"
                     /gene_synonym="RGD1304711"
                     /inference="alignment:Splign:2.1.0"
     exon            1167..1320
                     /gene="Ints10"
                     /gene_synonym="RGD1304711"
                     /inference="alignment:Splign:2.1.0"
     exon            1321..1403
                     /gene="Ints10"
                     /gene_synonym="RGD1304711"
                     /inference="alignment:Splign:2.1.0"
     exon            1404..1556
                     /gene="Ints10"
                     /gene_synonym="RGD1304711"
                     /inference="alignment:Splign:2.1.0"
     exon            1557..1665
                     /gene="Ints10"
                     /gene_synonym="RGD1304711"
                     /inference="alignment:Splign:2.1.0"
     exon            1666..1745
                     /gene="Ints10"
                     /gene_synonym="RGD1304711"
                     /inference="alignment:Splign:2.1.0"
     exon            1746..1908
                     /gene="Ints10"
                     /gene_synonym="RGD1304711"
                     /inference="alignment:Splign:2.1.0"
     exon            1909..2002
                     /gene="Ints10"
                     /gene_synonym="RGD1304711"
                     /inference="alignment:Splign:2.1.0"
     exon            2003..2392
                     /gene="Ints10"
                     /gene_synonym="RGD1304711"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caccggaagg gctggaagtc ggggccatgt cggcccaggg cgactgtgag tttctggtgc
       61 agcgagcccg ggagctagtg ccccaggacc tgtgggcagc caaggcgtgg ctgatcacag
      121 cccgcagcct ctacccggcc gacttcaaca tccagtatga gatgtacacc atcgaacgga
      181 atgcagagag gactgccacc gcagggaggt tgctgtatga catgtttgtg aatttcccag
      241 accagccggt ggtgtggaga gaaatcagta tcataacatc agcgttgagg aatgattcgc
      301 aagataagca aacccagttt ttaagaagtt tatttgaaac ccttccgggt cgggtccagt
      361 gtgaaatgct actgaaggtg actgagcagt gcttcaacac gctggagcga tcggagatgc
      421 tgctgctgct gctgaggcgt ttccctgaga cggtggtgca gcacggggtt ggccttgggg
      481 aggcactgct ggaagctgag accattgaag aacaagaatc ccctgttaac tgctttagaa
      541 agctgtttgt ctgcgacgtc cttcctctaa taatcaacaa ccatgatgtt cgcttgcctg
      601 ccaatctgtt atataaatac ttgaacaaag cagctgaatt ttacatcaac tatgtcactc
      661 ggtccacaca gttggaaaac cagcatcaag gtgcaccaga tacatctgac ttaatgtcac
      721 ctagcaaacg tagctctcag aagtacataa tagagggact gactgagaaa tcgtcccaca
      781 ttgtcgaccc ttgggagagg ttgtttaaga ttctgaatgt cgttggaatg agatgcgagt
      841 ggcagatgga taaaggaaga cgaagctgta gtgacatgct gcaccggatg aaggagctct
      901 gcagatacat gaacagcttc gacagcgaag ctcataccaa gtataaaaac caagtgctct
      961 actccaccat gctggtgctc ttcaagagtg cgttccagta catcagcagc atccagccat
     1021 ctctcttcca aggtcctaac gccccaagcc aggttccact agtccttctg gaagatgtag
     1081 ccaatgtgta tggtgatgta gaaattgacc gcagtaaaca catacacaag aagaggaagc
     1141 tagctgaggg aagagaaaaa accatgagct cagatgacga agagtgttca gcgaaaggca
     1201 gaaatcggca cattgttgtc agtaaggctg acctcagcaa ctccatcgaa gtgctggaga
     1261 gcttcaaact ggccagggag agctgggagt tactctactc tctggaattc cttgacaaag
     1321 aatttacaag aatttgtttg gcttggaaga cagacacctg gctatggctg agaatcttcc
     1381 tcacagatat gatcatctac cagggtcagt ataagaaggc aatagccagt ctgcatcact
     1441 tagcagctct ccaaggatcc ctttcccagc cacagatcac aggacagggg actttagaac
     1501 accagagggc gctcatccaa ctggcaacat gtcactttgc tctgggggag tacagaatga
     1561 catgtgagaa ggtcctggat ctgatgtgct acatggtgct ccccatacag gatggaggga
     1621 agtcgcagga agagccgtcc aaagtaaagc ccaagtgtag aaaaggtttg gatctgaagc
     1681 ttctgccctg taccagcaag gctattatgc cgtactgctt gcacttgatg ctggcctgct
     1741 ttaagctgag agcttttaca gacaacagag acgacatggc actgggccat gtgattgtcc
     1801 tgctccaaca ggagtggcca cggggagaga accttttcct gaaagccatc agtaagattt
     1861 gccagcaagg aaatttccag tatgagaact tcttcagcta tgttacaaac attgatatgc
     1921 tggaggaatt tgcttattta agaacccagg aaggagggaa gattcatctg gaattactcc
     1981 caaatcaagg aatgctgatc aagcaccaca cagtcactcg aggcatcacc aaaggtgtga
     2041 aggaggactt ccgcctggcc atggagcgcc aggtctcccg ctgtggtgag aacctgatgg
     2101 tggtcctgca tcgcttctgc attaatgaga agatcctgct cctgcagact ctgacctgat
     2161 cgacctccct cctggccacc agcagctcag ctgggacaag cgctgccaga ccagggctgg
     2221 ggaagaagga agacaccaag ttctaactcc cttagttgct tcaaagttat cccaagagtt
     2281 agggagttgt ttctattttt aagacttcgg gttttttaat ttgtacaaaa taagagtcaa
     2341 tccattttgt aaataaaaat cctaaaagtt tgaagtttgg aaaaaaacct taaaaaaaaa
     2401 aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//
